review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Sergio Lavandero | Q30112219 |
Roberto Bravo | Q57015059 | ||
Valentina Parra | Q58907470 | ||
Natalia Torrealba | Q58907566 | ||
P2093 | author name string | Andrew F G Quest | |
Joseph A Hill | |||
Antonio Zorzano | |||
Enrique Jaimovich | |||
Andrea E Rodriguez | |||
Damián Gatica | |||
Zhao V Wang | |||
Felipe Paredes | |||
P2860 | cites work | Atlasin GTPases shape up ER networks | Q84418565 |
Autophagy eliminates a specific species of misfolded procollagen and plays a protective role in cell survival against ER stress | Q84725704 | ||
Cardioprotection by endoplasmic reticulum stress-induced autophagy | Q84778523 | ||
The potential of proteasome inhibitors in cancer therapy | Q94700475 | ||
A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome) | Q22003951 | ||
Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors | Q22008465 | ||
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 | ||
Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress | Q22254718 | ||
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress | Q24290818 | ||
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response | Q24290935 | ||
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78 | Q24293643 | ||
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle | Q24296412 | ||
Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER | Q24296860 | ||
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol | Q24297732 | ||
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation | Q24298757 | ||
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT | Q24299291 | ||
Luman is capable of binding and activating transcription from the unfolded protein response element | Q24300509 | ||
Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element | Q24301000 | ||
Dysregulation of HSG triggers vascular proliferative disorders | Q24301690 | ||
Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations | Q24301868 | ||
Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1 | Q24302464 | ||
ER stress and the unfolded protein response | Q35986601 | ||
Insulin gene mutations as a cause of permanent neonatal diabetes | Q36002587 | ||
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. | Q36119444 | ||
The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags | Q36153965 | ||
Isolation and characterization of the sarcoplasmic reticulum of skeletal muscle | Q36194383 | ||
Microtubules and the endoplasmic reticulum are highly interdependent structures | Q36215523 | ||
Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals | Q36241923 | ||
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities | Q36321572 | ||
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
Role of the unfolded protein response in cell death | Q36351719 | ||
From acute ER stress to physiological roles of the Unfolded Protein Response | Q36362397 | ||
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. | Q36393034 | ||
Remodelling Ca2+ signalling systems and cardiac hypertrophy | Q36424286 | ||
Etiology of insulin resistance | Q36431215 | ||
Calcium uptake by rat kidney mitochondria | Q36441249 | ||
Protein quality control in the early secretory pathway | Q36446833 | ||
Interaction of the smooth endoplasmic reticulum and mitochondria | Q36482062 | ||
Rough sheets and smooth tubules | Q36562472 | ||
Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus | Q36597501 | ||
A century of Alzheimer's disease | Q36643414 | ||
Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming | Q36702104 | ||
Methods for monitoring autophagy from yeast to human | Q36708691 | ||
The subcellular distribution of calnexin is mediated by PACS-2 | Q36739888 | ||
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients | Q36778260 | ||
ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo | Q36802449 | ||
Modulation of the ryanodine receptor and intracellular calcium | Q36824050 | ||
Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells. | Q36836856 | ||
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. | Q36870862 | ||
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells | Q36910693 | ||
Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? | Q36989869 | ||
Endoplasmic reticulum stress in the heart | Q36996959 | ||
Chemical induction of the unfolded protein response in the liver increases glucose production and is activated during insulin-induced hypoglycaemia in rats | Q37001677 | ||
Calcium dysregulation in Alzheimer's disease | Q37012642 | ||
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease | Q28854335 | ||
Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction | Q28854565 | ||
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
Regulation mechanisms and signaling pathways of autophagy | Q29547416 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
Autophagy is activated for cell survival after endoplasmic reticulum stress | Q29614485 | ||
Global and societal implications of the diabetes epidemic | Q29614551 | ||
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses | Q29615239 | ||
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress | Q29615495 | ||
IRE1 signaling affects cell fate during the unfolded protein response | Q29615502 | ||
The biology of vascular endothelial growth factor | Q29615946 | ||
Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses | Q29616076 | ||
mTOR regulation of autophagy | Q29616301 | ||
The Beclin 1 network regulates autophagy and apoptosis | Q29616539 | ||
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes | Q29616567 | ||
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis | Q29617644 | ||
Mitofusin 2 tethers endoplasmic reticulum to mitochondria | Q29619861 | ||
ER tubules mark sites of mitochondrial division | Q29619991 | ||
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus | Q29620179 | ||
SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production | Q30482542 | ||
Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport | Q30483267 | ||
Reduced translocation of nascent prion protein during ER stress contributes to neurodegeneration | Q30483989 | ||
STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. | Q30485016 | ||
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering | Q30496639 | ||
Overexpressed protein disulfide isomerase in brains of patients with sporadic Creutzfeldt-Jakob disease | Q30871448 | ||
PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice | Q30945763 | ||
The nuclear envelope; its structure and relation to cytoplasmic membranes | Q30983985 | ||
Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein | Q33253898 | ||
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response | Q33264844 | ||
Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation | Q33291107 | ||
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals | Q33345339 | ||
Transcriptional regulation of VEGF-A by the unfolded protein response pathway | Q33539754 | ||
Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes | Q33549736 | ||
Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers | Q24302559 | ||
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response | Q24303865 | ||
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha | Q24310536 | ||
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy | Q24312147 | ||
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response | Q24314664 | ||
Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis | Q24314799 | ||
A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response | Q24317491 | ||
DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation | Q24320231 | ||
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
A class of dynamin-like GTPases involved in the generation of the tubular ER network | Q24322595 | ||
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction | Q24324602 | ||
Interaction of ATF6 and serum response factor | Q24336048 | ||
BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer | Q24337349 | ||
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control | Q24522941 | ||
Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ. | Q24537406 | ||
Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. | Q24541469 | ||
Identification of TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: its autoregulation by stress and interaction with ATF6. | Q24550967 | ||
A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation | Q24600318 | ||
An ER-mitochondria tethering complex revealed by a synthetic biology screen | Q24618405 | ||
An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown | Q24628769 | ||
The nuclear envelope | Q24634678 | ||
Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis | Q24645884 | ||
MAM: more than just a housekeeper | Q24648220 | ||
Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells | Q24648786 | ||
Inhibition of p97-dependent protein degradation by Eeyarestatin I | Q24648805 | ||
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival | Q24653078 | ||
One step at a time: endoplasmic reticulum-associated degradation | Q24658302 | ||
Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins | Q24658387 | ||
Divergent effects of PERK and IRE1 signaling on cell viability | Q27438124 | ||
The structure of the PERK kinase domain suggests the mechanism for its activation | Q27667715 | ||
Sec61p is part of the endoplasmic reticulum-associated degradation machinery | Q27930621 | ||
Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins | Q27931299 | ||
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins | Q27932183 | ||
The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum | Q27932262 | ||
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins | Q27934337 | ||
IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae | Q27935778 | ||
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol | Q27936514 | ||
Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites | Q27937449 | ||
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response | Q27938493 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p | Q27938951 | ||
A class of membrane proteins shaping the tubular endoplasmic reticulum | Q27940194 | ||
In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human Diseases | Q28109625 | ||
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response | Q28139950 | ||
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD | Q28140882 | ||
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome | Q28142981 | ||
Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2 | Q28185092 | ||
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival | Q28255981 | ||
Calcium pumps of plasma membrane and cell interior | Q28257824 | ||
ERAD: the long road to destruction | Q28264823 | ||
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis | Q28275274 | ||
The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is selectively recognized by the 3F3A antibody within a subdomain of the endoplasmic reticulum | Q28276396 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
ER chaperones in mammalian development and human diseases | Q28300625 | ||
Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology | Q37860033 | ||
Role of calcium ions in regulation of mammalian intramitochondrial metabolism | Q37875647 | ||
Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress | Q38316703 | ||
Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response | Q38326929 | ||
Effect on tumor cells of blocking survival response to glucose deprivation | Q38337197 | ||
Regulation of autophagy by ATF4 in response to severe hypoxia. | Q38343634 | ||
Identification of a consensus element recognized and cleaved by IRE1 alpha. | Q38343711 | ||
AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1 | Q38348926 | ||
Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways | Q38394944 | ||
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival. | Q38431247 | ||
GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer | Q38436413 | ||
IRE1-dependent activation of AMPK in response to nitric oxide | Q38960360 | ||
Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK | Q39142751 | ||
Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 | Q39315996 | ||
The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte survival | Q39467135 | ||
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth | Q39470144 | ||
AMP-activated protein kinase activation during cardioplegia-induced hypoxia/reoxygenation injury attenuates cardiomyocytic apoptosis via reduction of endoplasmic reticulum stress | Q39592947 | ||
A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking. | Q39603113 | ||
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. | Q39676476 | ||
Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum | Q39776644 | ||
Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cells | Q39802567 | ||
Atlastin-1, the dynamin-like GTPase responsible for spastic paraplegia SPG3A, remodels lipid membranes and may form tubules and vesicles in the endoplasmic reticulum | Q39830086 | ||
Prolyl hydroxylase inhibition attenuates post-ischemic cardiac injury via induction of endoplasmic reticulum stress genes. | Q39838507 | ||
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis | Q39843795 | ||
Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis | Q39845179 | ||
Basal autophagy is involved in the degradation of the ERAD component EDEM1. | Q39876239 | ||
Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia | Q39881247 | ||
pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation. | Q39898784 | ||
Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance | Q39925487 | ||
c-Jun inhibits thapsigargin-induced ER stress through up-regulation of DSCR1/Adapt78. | Q39959228 | ||
Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. | Q39962425 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas | Q39981994 | ||
Endoplasmic reticulum stress responses | Q37014237 | ||
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium | Q37039595 | ||
Knockdown of p180 eliminates the terminal differentiation of a secretory cell line | Q37061525 | ||
Regulation of the cardiac muscle ryanodine receptor by O(2) tension and S-nitrosoglutathione | Q37085577 | ||
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum | Q37186859 | ||
Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection | Q37207734 | ||
Metabolic remodelling of the failing heart: beneficial or detrimental? | Q37293624 | ||
Membrane phospholipid synthesis and endoplasmic reticulum function | Q37308781 | ||
Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum. | Q37365629 | ||
Heat-shock proteins in infection-mediated inflammation-induced tumorigenesis | Q37381884 | ||
Dysregulation of calcium homeostasis in Alzheimer's disease | Q37428942 | ||
Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. | Q37429250 | ||
O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death. | Q37430909 | ||
The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2 | Q37433349 | ||
Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase | Q37456875 | ||
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease | Q37459062 | ||
Peripheral ER structure and function | Q37485204 | ||
Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities | Q37576204 | ||
Calcium pumps in health and disease | Q37605483 | ||
Membrane biogenesis: networking at the ER with atlastin | Q37613818 | ||
An emerging role of mTOR in lipid biosynthesis. | Q37641438 | ||
Calcium binding chaperones of the endoplasmic reticulum | Q37679566 | ||
Calcium dysregulation in amyotrophic lateral sclerosis | Q37684077 | ||
The fateful encounter of mitochondria with calcium: how did it happen? | Q37729378 | ||
Is Alzheimer's disease a disorder of mitochondria-associated membranes? | Q37737504 | ||
ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum | Q37784156 | ||
An intelligent sarco-endoplasmic reticulum Ca2+ store: release and leak channels have differential access to a concealed Ca2+ pool. | Q37785336 | ||
IP(3) receptors: toward understanding their activation. | Q37803478 | ||
Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease | Q37804650 | ||
Biology of Endoplasmic Reticulum Stress in the Heart | Q37808904 | ||
Modulation of cardiac ryanodine receptor activity by ROS and RNS. | Q37825162 | ||
Unfolded protein response in cancer: the physician's perspective | Q37846249 | ||
Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis | Q37849479 | ||
Interactions between mammalian cell DNA and inorganic platinum compounds. II. Interstrand cross-linking of isolated and cellular DNA by platinum(IV) compounds | Q47866082 | ||
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. | Q47942024 | ||
ER vesicles and mitochondria move and communicate at synapses | Q48370191 | ||
Ca2+ regulation of interactions between endoplasmic reticulum chaperones. | Q50520041 | ||
Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets. | Q51006407 | ||
Intricate links between ER stress and apoptosis. | Q51747417 | ||
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma. | Q51753373 | ||
Endoplasmic reticulum stress: a new pathway to induce autophagy. | Q51997673 | ||
Presenilins and Alzheimer disease: the calcium conspiracy. | Q53382538 | ||
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. | Q53616050 | ||
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. | Q53848758 | ||
mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome. | Q54351691 | ||
Apelin-13 protects the heart against ischemia-reperfusion injury through inhibition of ER-dependent apoptotic pathways in a time-dependent fashion. | Q54570712 | ||
Attenuation of CHOP-mediated myocardial apoptosis in pressure-overloaded dominant negative p38α mitogen-activated protein kinase mice. | Q54580126 | ||
Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis | Q54640151 | ||
Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone. | Q55474365 | ||
Climp-63-mediated binding of microtubules to the ER affects the lateral mobility of translocon complexes | Q56565426 | ||
Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation | Q57267080 | ||
Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes | Q64377708 | ||
Demonstration of a calcium requirement for secretory protein processing and export. Differential effects of calcium and dithiothreitol | Q67754688 | ||
Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response | Q73127387 | ||
The role of mitochondria in presynaptic calcium handling at a ribbon synapse | Q73523712 | ||
Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response | Q74359929 | ||
Cellular sensitization to cisplatin and carboplatin with decreased removal of platinum-DNA adduct by glucose-regulated stress | Q77878619 | ||
Ca ion uptake by rat kidney mitochondria and its dependence on respiration and phosphorylation | Q79434435 | ||
Cellular tolerance of prion protein PrP in yeast involves proteolysis and the unfolded protein response | Q79814435 | ||
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 | Q80553475 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II | Q81144490 | ||
Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6 | Q83118076 | ||
Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling | Q83300064 | ||
C/EBP homologous protein deficiency attenuates myocardial reperfusion injury by inhibiting myocardial apoptosis and inflammation | Q83433872 | ||
Infusion of glucose and lipids at physiological rates causes acute endoplasmic reticulum stress in rat liver | Q83810163 | ||
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis | Q40002274 | ||
Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells | Q40128062 | ||
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis | Q40144533 | ||
Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II). | Q40164655 | ||
Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy | Q40176298 | ||
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. | Q40179972 | ||
EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation. | Q40229528 | ||
Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. | Q40236795 | ||
Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells | Q40310345 | ||
The expression and functional characterization of sigma (sigma) 1 receptors in breast cancer cell lines | Q40334631 | ||
ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity | Q40386955 | ||
The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity. | Q40445820 | ||
Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response | Q40500396 | ||
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. | Q40519913 | ||
Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1-mediated nuclear factor (NF)-kappaB and AP-1 activation. | Q40526557 | ||
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress | Q40527936 | ||
Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo | Q40534877 | ||
Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4. | Q40595070 | ||
Molecular and cellular physiology of intracellular calcium stores | Q40674713 | ||
Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane | Q40792995 | ||
Calcium regulates the association between mitochondria and a smooth subdomain of the endoplasmic reticulum | Q40854212 | ||
In vitro formation of the endoplasmic reticulum occurs independently of microtubules by a controlled fusion reaction | Q40895705 | ||
Enzyme-membrane relationship in phenobarbital induction of synthesis of drug-metabolizing enzyme system and proliferation of endoplasmic membranes | Q41078705 | ||
Hypersensitivity to DNA cross-linking agents associated with up-regulation of glucose-regulated stress protein GRP78. | Q41078765 | ||
Mechanism of polypeptide translocation into the endoplasmic reticulum | Q41239618 | ||
Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. | Q41256595 | ||
Protein translocation across the membrane of the endoplasmic reticulum | Q41364028 | ||
The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation. | Q41465002 | ||
Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes | Q41609588 | ||
Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals | Q41700856 | ||
Protein translocation: tunnel vision | Q41708899 | ||
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis | Q41791624 | ||
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension | Q41829078 | ||
Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. | Q41844309 | ||
X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas. | Q41859494 | ||
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis | Q41904044 | ||
The endoplasmic reticulum. | Q41939884 | ||
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis | Q42004487 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
Prion pathogenesis is independent of caspase-12. | Q42068269 | ||
Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake | Q42118696 | ||
Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice | Q42173352 | ||
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease | Q42474769 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
CREB3 subfamily transcription factors are not created equal: Recent insights from global analyses and animal models. | Q42760035 | ||
Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum | Q42824803 | ||
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis. | Q42832143 | ||
ATF6 is important under both pathological and physiological states in the heart | Q43104574 | ||
Lead induces the expression of endoplasmic reticulum chaperones GRP78 and GRP94 in vascular endothelial cells via the JNK-AP-1 pathway | Q43195284 | ||
Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload | Q43207763 | ||
N-glycosylation of ATF6beta is essential for its proteolytic cleavage and transcriptional repressor function to ATF6alpha | Q43289215 | ||
Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling | Q44267711 | ||
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. | Q44393459 | ||
Regular exercise is associated with a protective metabolic phenotype in the rat heart | Q44856585 | ||
Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6. | Q45010270 | ||
Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on endoplasmic reticulum stress response gene expression and cell viability | Q45101812 | ||
Expression profiling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy | Q46534803 | ||
Gene expression profiling of the preclinical scrapie-infected hippocampus | Q46578942 | ||
Cardiac fatty acid metabolism is preserved in the compensated hypertrophic rat heart | Q46681807 | ||
ER-phagy: selective autophagy of the endoplasmic reticulum. | Q46683304 | ||
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. | Q46742618 | ||
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression | Q46955933 | ||
Functional characterization of Drosophila melanogaster PERK eukaryotic initiation factor 2alpha (eIF2alpha) kinase. | Q47071973 | ||
Endoplasmic reticulum membrane tubules are distributed by microtubules in living cells using three distinct mechanisms | Q47849817 | ||
Endoplasmic reticulum architecture: structures in flux. | Q34684405 | ||
Functional coupling between ryanodine receptors, mitochondria and Ca(2+) ATPases in rat submandibular acinar cells | Q34692023 | ||
Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis. | Q34695923 | ||
A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis | Q34803685 | ||
Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity | Q34854373 | ||
ER calcium and Alzheimer's disease: in a state of flux | Q34966217 | ||
Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease | Q34982214 | ||
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease | Q34988301 | ||
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress | Q35041282 | ||
Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy | Q35045900 | ||
The endoplasmic reticulum: a multifunctional signaling organelle | Q35051249 | ||
Mutant fibrinogen cleared from the endoplasmic reticulum via endoplasmic reticulum-associated protein degradation and autophagy: an explanation for liver disease | Q35088205 | ||
Lipid transfer and signaling at organelle contact sites: the tip of the iceberg | Q35141334 | ||
Cholesterol at the endoplasmic reticulum: roles of the sigma-1 receptor chaperone and implications thereof in human diseases | Q35163209 | ||
T-tubule biogenesis and triad formation in skeletal muscle and implication in human diseases | Q35166273 | ||
PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment | Q35192134 | ||
Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress | Q35221396 | ||
PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism | Q35229188 | ||
Atorvastatin inhibits myocardial cell apoptosis in a rat model with post-myocardial infarction heart failure by downregulating ER stress response | Q35233981 | ||
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress. | Q35551757 | ||
The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction | Q35572373 | ||
Regulation of apoptosis by endoplasmic reticulum pathways. | Q35591699 | ||
Organization of translocon complexes in ER membranes | Q35594198 | ||
Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes | Q35641724 | ||
Endoplasmic reticulum stress triggers autophagy | Q35690087 | ||
Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes | Q35748146 | ||
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy | Q35776381 | ||
Insulin receptor substrate proteins and diabetes | Q35793714 | ||
Inositol 1,4,5-trisphosphate receptors as signal integrators | Q35799975 | ||
Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes | Q35838612 | ||
The role of the unfolded protein response in tumour development: friend or foe? | Q35968425 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells | Q28513964 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver | Q28577788 | ||
Sarco/endoplasmic reticulum calcium ATPase-2 expression is regulated by ATF6 during the endoplasmic reticulum stress response: intracellular signaling of calcium stress in a cardiac myocyte model system | Q28578430 | ||
OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes | Q28580776 | ||
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway | Q28583302 | ||
ER-stress-inducible Herp, facilitates the degradation of immature nicastrin | Q28586218 | ||
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation | Q28587852 | ||
Reduction of spermatogenesis but not fertility in Creb3l4-deficient mice | Q28588285 | ||
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis | Q28591480 | ||
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
Gene-specific regulation by general translation factors | Q28611181 | ||
The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response | Q28646118 | ||
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. | Q33559643 | ||
Physical coupling supports the local Ca2+ transfer between sarcoplasmic reticulum subdomains and the mitochondria in heart muscle | Q33574066 | ||
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response | Q33631257 | ||
Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs | Q33654233 | ||
Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response | Q33713564 | ||
Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity | Q33733839 | ||
Detergent-resistant microdomains determine the localization of sigma-1 receptors to the endoplasmic reticulum-mitochondria junction | Q33754855 | ||
Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress | Q33786940 | ||
PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis | Q33868451 | ||
Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway | Q33891036 | ||
Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons | Q33966472 | ||
PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage | Q33977034 | ||
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics | Q33986242 | ||
SERCA pump isoforms: their role in calcium transport and disease | Q34002326 | ||
Cholesterol, the central lipid of mammalian cells | Q34021021 | ||
Ryanodine receptors: structure, expression, molecular details, and function in calcium release. | Q34024377 | ||
ER sliding dynamics and ER-mitochondrial contacts occur on acetylated microtubules | Q34069992 | ||
β-AR blockers suppresses ER stress in cardiac hypertrophy and heart failure | Q34071906 | ||
Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase | Q34119006 | ||
Coordination of ATF6-mediated transcription and ATF6 degradation by a domain that is shared with the viral transcription factor, VP16. | Q34120076 | ||
ER calcium and the functions of intracellular organelles | Q34132512 | ||
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling | Q34179244 | ||
Rab32 Modulates Apoptosis Onset and Mitochondria-associated Membrane (MAM) Properties | Q34181492 | ||
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis | Q34192744 | ||
Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death | Q34198372 | ||
IP(3) receptors: the search for structure. | Q34313146 | ||
Activation of mitochondrial energy metabolism protects against cardiac failure | Q34424919 | ||
The type III inositol 1,4,5-trisphosphate receptor preferentially transmits apoptotic Ca2+ signals into mitochondria | Q34455046 | ||
Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner | Q34568352 | ||
Adenylate Kinase 2 Links Mitochondrial Energy Metabolism to the Induction of the Unfolded Protein Response | Q34575683 | ||
Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk. | Q34582973 | ||
The oligomeric state of Derlin-1 is modulated by endoplasmic reticulum stress | Q34622014 | ||
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex | Q34673344 | ||
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 215-290 | |
P577 | publication date | 2013-01-01 | |
P1433 | published in | International Review of Cell and Molecular Biology | Q26842011 |
P1476 | title | Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration | |
P478 | volume | 301 |
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