| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M408466200 |
| P698 | PubMed publication ID | 15299016 |
| P50 | author | Jingshi Shen | Q59660759 |
| P2093 | author name string | Ron Prywes | |
| P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
| ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
| Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans | Q28145545 | ||
| Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis | Q28213796 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi | Q28217040 | ||
| Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease | Q28344251 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment | Q28644805 | ||
| ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
| Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER | Q29615171 | ||
| Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation | Q29618286 | ||
| A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6. | Q34202341 | ||
| Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain | Q34207965 | ||
| The SREBP pathway--insights from Insigs and insects | Q34223258 | ||
| The unfolding tale of the unfolded protein response | Q34486042 | ||
| The unfolded protein response in nutrient sensing and differentiation | Q34664763 | ||
| Transcriptional and translational control in the Mammalian unfolded protein response | Q34762452 | ||
| Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides | Q35057311 | ||
| YaeL proteolysis of RseA is controlled by the PDZ domain of YaeL and a Gln-rich region of RseA. | Q40323844 | ||
| Membrane topology of S2P, a protein required for intramembranous cleavage of sterol regulatory element-binding proteins | Q40939802 | ||
| Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release | Q43695967 | ||
| Reconstitution of gamma-secretase activity | Q44393107 | ||
| Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. | Q52583319 | ||
| Transport-Dependent Proteolysis of SREBP | Q54231898 | ||
| P433 | issue | 41 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 6 | |
| P304 | page(s) | 43046-43051 | |
| P577 | publication date | 2004-08-06 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6 | |
| P478 | volume | 279 |
| Q35354864 | A review of the mammalian unfolded protein response. |
| Q33500340 | Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation |
| Q35605031 | Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network |
| Q36068837 | An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy |
| Q51035119 | BINDING PROTEIN is a master regulator of the endoplasmic reticulum stress sensor/transducer bZIP28 in Arabidopsis. |
| Q42115604 | Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. |
| Q42410198 | Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress |
| Q40329235 | Discordant regulatory changes in monocrotaline-induced megalocytosis of lung arterial endothelial and alveolar epithelial cells |
| Q50528588 | Driving Cancer Tumorigenesis and Metastasis Through UPR Signaling. |
| Q36074357 | ENDOPLASMIC RETICULUM STRESS IN SEPSIS. |
| Q28078536 | ER Stress-Mediated Signaling: Action Potential and Ca(2+) as Key Players |
| Q92333949 | ERp18 regulates activation of ATF6α during unfolded protein response |
| Q40199093 | Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population |
| Q49890898 | Elucidating post-translational regulation of mouse CREB3 in Neuro2a cells. |
| Q35902352 | Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis |
| Q38073952 | Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration |
| Q40282765 | Endoplasmic reticulum stress as a pro-fibrotic stimulus |
| Q35882857 | Endoplasmic reticulum stress implicated in the development of renal fibrosis |
| Q52642205 | Endoplasmic reticulum stress in pulmonary fibrosis. |
| Q40421034 | Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. |
| Q36080483 | Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes |
| Q36844431 | Endoplasmic reticulum stress: signaling the unfolded protein response |
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| Q24302321 | GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis |
| Q34881229 | Heat induces the splicing by IRE1 of a mRNA encoding a transcription factor involved in the unfolded protein response in Arabidopsis |
| Q34982248 | How intramembrane proteases bury hydrolytic reactions in the membrane. |
| Q36363531 | Identification and characterization of five intramembrane metalloproteases in Anabaena variabilis |
| Q35676629 | Inhibition of regulated proteolysis by RseB. |
| Q26864403 | Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus |
| Q50296769 | MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) |
| Q50296770 | MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) |
| Q96230836 | MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6 |
| Q37788073 | New insights into S2P signaling cascades: regulation, variation, and conservation. |
| Q38346133 | Organelle autoregulation-stress responses in the ER, Golgi, mitochondria and lysosome |
| Q37739513 | Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM). |
| Q34024253 | PERK (EIF2AK3) regulates proinsulin trafficking and quality control in the secretory pathway |
| Q90612369 | Promotion of Axon Growth by the Secreted End of a Transcription Factor |
| Q37151090 | Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α. |
| Q42952040 | Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress |
| Q38149888 | Roles of regulated intramembrane proteolysis in virus infection and antiviral immunity |
| Q42871025 | Salt stress responses in Arabidopsis utilize a signal transduction pathway related to endoplasmic reticulum stress signaling |
| Q50603977 | Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis |
| Q37603972 | Stress sensing in plants by an ER stress sensor/transducer, bZIP28 |
| Q33330462 | Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways |
| Q90597572 | The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases |
| Q34576070 | The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and Cancer |
| Q89552648 | The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias |
| Q35551757 | The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress. |
| Q38201042 | The essential biology of the endoplasmic reticulum stress response for structural and computational biologists. |
| Q50506302 | The novel resveratrol derivative 3,5-diethoxy-3',4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro |
| Q26851197 | The site-2 protease |
| Q26852080 | The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein folding |
| Q33565770 | Translational control of gene expression in the gonadotrope |
| Q33320586 | Unfolded protein response and cell death after depletion of brefeldin A-inhibited guanine nucleotide-exchange protein GBF1 |
| Q28589308 | Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion |
| Q36759654 | YiQiFuMai Powder Injection Ameliorates Cerebral Ischemia by Inhibiting Endoplasmic Reticulum Stress-Mediated Neuronal Apoptosis |
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