scholarly article | Q13442814 |
P2093 | author name string | Arun J Sanyal | |
Sophie C Cazanave | |||
Bubu A Banini | |||
Manoela Mota | |||
P2860 | cites work | Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis | Q24625697 |
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. | Q24815740 | ||
Carbohydrate intake and nonalcoholic fatty liver disease: fructose as a weapon of mass destruction | Q26991952 | ||
Fructose as a key player in the development of fatty liver disease | Q27014596 | ||
Recent insights on the role of cholesterol in non-alcoholic fatty liver disease | Q28082693 | ||
Clinical utility of LC3 and p62 immunohistochemistry in diagnosis of drug-induced autophagic vacuolar myopathies: a case-control study | Q28482758 | ||
A lipidomic analysis of nonalcoholic fatty liver disease. | Q44931121 | ||
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease | Q44934521 | ||
Hepatospecific effects of fructose on c-jun NH2-terminal kinase: implications for hepatic insulin resistance | Q44938048 | ||
Poly(ADP‐ribose) polymerase 1 is involved in glucose toxicity through SIRT1 modulation in HepG2 hepatocytes | Q44965464 | ||
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway | Q44967749 | ||
No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial | Q44997998 | ||
Role of p53 in the cellular response following oleic acid accumulation in Chang liver cells | Q46718232 | ||
Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis | Q46751757 | ||
Hepatocyte autophagy is linked to C/EBP-homologous protein, Bcl2-interacting mediator of cell death, and BH3-interacting domain death agonist gene expression | Q50216534 | ||
Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection. | Q50448712 | ||
Changes in insulin action, triglycerides, and lipid composition during sucrose feeding in rats. | Q51578666 | ||
Hepatic inflammation induced by high-fructose diet is associated with altered 11βHSD1 expression in the liver of Wistar rats. | Q52646591 | ||
Statin use and non-alcoholic steatohepatitis in at risk individuals. | Q53504568 | ||
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. | Q53555710 | ||
A high fructose diet affects the early steps of insulin action in muscle and liver of rats. | Q54050337 | ||
Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent. | Q54334813 | ||
Fatty acid transporters involved in the palmitate and oleate induced insulin resistance in primary rat hepatocytes | Q62034066 | ||
Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1 | Q71743266 | ||
Comparison of the effects of sucrose and fructose on insulin action and glucose tolerance | Q72997993 | ||
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis | Q82677113 | ||
Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease | Q83067058 | ||
Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice | Q83677023 | ||
Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet | Q85274225 | ||
Omega-3 polyunsaturated fatty acids in treating non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial | Q85319932 | ||
Endoplasmic reticulum stress and Nrf2 repression in circulating cells of type 2 diabetic patients without the recommended glycemic goals | Q86298171 | ||
Standard short-term diet ameliorates the lipid profile altered by a fructose-rich diet in rats | Q87069709 | ||
Downregulating SOCS3 with siRNA ameliorates insulin signaling and glucose metabolism in hepatocytes of IUGR rats with catch-up growth | Q87369430 | ||
Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis | Q40960591 | ||
Effects of inhibitors of key enzymes of sphingolipid metabolism on insulin-induced glucose uptake and glycogen synthesis in liver cells of old rats | Q41261653 | ||
Individual CLA Isomers, c9t11 and t10c12, Prevent Excess Liver Glycogen Storage and Inhibit Lipogenic Genes Expression Induced by High-Fructose Diet in Rats. | Q41459356 | ||
Circulating phospholipid profiling identifies portal contribution to NASH signature in obesity | Q41755444 | ||
Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet-induced NASH model | Q41761778 | ||
Attenuation of oxidative stress, inflammation and insulin resistance by allium sativum in fructose-fed male rats | Q41932791 | ||
Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes | Q41985780 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress | Q42148009 | ||
Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity | Q42409618 | ||
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase | Q42563412 | ||
Sirt1 mediates the effect of the heme oxygenase inducer, cobalt protoporphyrin, on ameliorating liver metabolic damage caused by a high-fat diet | Q42701630 | ||
Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice | Q42717472 | ||
Oxidative stress induced by high-glucose diet in liver of C57BL/6J mice and its underlying mechanism | Q43136171 | ||
Insulin resistance induced by high-fructose diet potentiates carbon tetrachloride hepatotoxicity | Q43183517 | ||
Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities | Q43552270 | ||
Inhibition of ceramide de novo synthesis reduces liver lipid accumulation in rats with nonalcoholic fatty liver disease | Q44037507 | ||
Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis | Q44697151 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis | Q28547365 | ||
Mediators of endoplasmic reticulum stress-induced apoptosis | Q29615496 | ||
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1. | Q33420360 | ||
Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells | Q33684205 | ||
Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death | Q33840334 | ||
High fat diet induced hepatic steatosis and insulin resistance: Role of dysregulated ceramide metabolism | Q33896110 | ||
Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance. | Q34166238 | ||
Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. | Q34206288 | ||
Ceramides and glucosylceramides are independent antagonists of insulin signaling | Q34384118 | ||
Recent advances in the development of farnesoid X receptor agonists | Q34464043 | ||
The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity | Q34512981 | ||
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes | Q34594406 | ||
Bax inhibition protects against free fatty acid-induced lysosomal permeabilization | Q34665604 | ||
Triglyceride accumulation protects against fatty acid-induced lipotoxicity | Q34866329 | ||
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial | Q35031127 | ||
Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells | Q35107757 | ||
Evaluation of dietary effects on hepatic lipids in high fat and placebo diet fed rats by in vivo MRS and LC-MS techniques. | Q35123226 | ||
Proteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis | Q35159970 | ||
Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients | Q35228266 | ||
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress. | Q35551757 | ||
New evidence for the role of ceramide in the development of hepatic insulin resistance | Q35551917 | ||
Death receptor 5 signaling promotes hepatocyte lipoapoptosis | Q35604362 | ||
Liver injury and fibrosis induced by dietary challenge in the Ossabaw miniature Swine | Q35610499 | ||
Intermittent but not constant high glucose induces ER stress and inflammation in human retinal pericytes | Q35627455 | ||
Retracted: Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet | Q35670773 | ||
Hepatic oxidative stress in fructose-induced fatty liver is not caused by sulfur amino acid insufficiency | Q35671121 | ||
Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease | Q35904142 | ||
Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis | Q35939383 | ||
Role of ceramides in nonalcoholic fatty liver disease | Q36129432 | ||
Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis | Q36243417 | ||
Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways | Q36421523 | ||
Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains | Q36712468 | ||
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice | Q36723099 | ||
Activation of PPARα ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress. | Q36867522 | ||
Omega 3 - Omega 6: What is right for the liver? | Q36942356 | ||
A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis | Q37189403 | ||
Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease | Q37405640 | ||
The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease | Q37412003 | ||
Bcl-2 family on guard at the ER. | Q37412841 | ||
Mcl-1 degradation during hepatocyte lipoapoptosis | Q37431628 | ||
JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis | Q37446730 | ||
Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes | Q37625425 | ||
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver. | Q37643931 | ||
The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity | Q37680167 | ||
The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome | Q37724585 | ||
Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: mechanisms and pathophysiological role | Q37887977 | ||
Interaction domains of p62: a bridge between p62 and selective autophagy | Q38093208 | ||
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy. | Q38172752 | ||
Biomarkers of liver cell death | Q38177569 | ||
Glycogen synthase kinase 3-mediated voltage-dependent anion channel phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation | Q38323405 | ||
Fructose containing sugars modulate mRNA of lipogenic genes ACC and FAS and protein levels of transcription factors ChREBP and SREBP1c with no effect on body weight or liver fat. | Q38329583 | ||
Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH. | Q38356462 | ||
Islet β-cell failure in type 2 diabetes--Within the network of toxic lipids | Q38406600 | ||
Cell death induced by endoplasmic reticulum stress. | Q38639996 | ||
Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress. | Q38882240 | ||
All-trans retinoic acid induces p53-depenent apoptosis in human hepatocytes by activating p14 expression via promoter hypomethylation | Q38892523 | ||
Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity | Q38911401 | ||
Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis | Q39000961 | ||
Plasma membrane phospholipase A2 controls hepatocellular fatty acid uptake and is responsive to pharmacological modulation: implications for nonalcoholic steatohepatitis | Q39005663 | ||
Liquid fructose down-regulates liver insulin receptor substrate 2 and gluconeogenic enzymes by modifying nutrient sensing factors in rats | Q39032673 | ||
CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis | Q39709114 | ||
Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis | Q39731721 | ||
Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes | Q39885259 | ||
Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism | Q39928700 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes | Q40064603 | ||
Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis | Q40108223 | ||
Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity | Q40146370 | ||
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells | Q40313352 | ||
Oxysterols induce mitochondrial impairment and hepatocellular toxicity in non-alcoholic fatty liver disease | Q40438293 | ||
P433 | issue | 8 | |
P921 | main subject | metabolic dysfunction–associated steatotic liver disease | Q1546498 |
fatty liver disease | Q6058862 | ||
P304 | page(s) | 1049-1061 | |
P577 | publication date | 2016-03-03 | |
P1433 | published in | Metabolism | Q15764354 |
P1476 | title | Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease | |
P478 | volume | 65 |
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