Regulation of translation initiation in eukaryotes: mechanisms and biological targets (scientific article (publication date: 20 February 2009))

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Q39144259	Effect of siRNA-mediated knockdown of eIF3c gene on survival of colon cancer cells
Q35972381	Effects of Weaning on Intestinal Upper Villus Epithelial Cells of Piglets
Q34995333	Effects of different per translational kinetics on the dynamics of a core circadian clock model
Q98624989	Effects of inducing apoptosis and inhibiting proliferation of siRNA on polyadenylate-binding protein-interacting protein 1 in tongue cell carcinoma
Q37859076	Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease
Q55209127	Effects of single amino acid deficiency on mRNA translation are markedly different for methionine versus leucine.
Q31068103	Efficient Translation of Pelargonium line pattern virus RNAs Relies on a TED-Like 3´-Translational Enhancer that Communicates with the Corresponding 5´-Region through a Long-Distance RNA-RNA Interaction.
Q49231209	Efficient and Accurate Translation Initiation Directed by TISU Involves RPS3 and RPS10e Binding and Differential Eukaryotic Initiation Factor 1A Regulation.
Q37629045	Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma
Q37622295	Elongation factor 2 diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions.
Q64107829	Emerging Role of Eukaryote Ribosomes in Translational Control
Q38156017	Emerging roles for post-transcriptional regulation in circadian clocks
Q47252604	Emerging roles of RNA-binding proteins in diabetes and their therapeutic potential in diabetic complications.
Q28084013	Endoplasmic reticulum quality control and systemic amyloid disease: Impacting protein stability from the inside out
Q34173536	Endoplasmic reticulum stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) protects against pressure overload-induced heart failure and lung remodeling
Q28071440	Engineering Translation in Mammalian Cell Factories to Increase Protein Yield: The Unexpected Use of Long Non-Coding SINEUP RNAs
Q26752604	Enterovirus Control of Translation and RNA Granule Stress Responses
Q45324801	Epstein-Barr virus protein EB2 stimulates translation initiation of mRNAs through direct interactions with both PABP and eIF4G.
Q35172899	Equol, an isoflavone metabolite, regulates cancer cell viability and protein synthesis initiation via c-Myc and eIF4G.
Q35101922	Erk in kidney diseases
Q36435592	Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine
Q29147399	Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression
Q34776278	Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB.
Q93185934	Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1): a target for cancer therapeutic intervention?
Q53684290	Eukaryotic Translation Initiation Factor 4 Gamma 1 (eIF4G1) is upregulated during Prostate cancer progression and modulates cell growth and metastasis.
Q35914014	Eukaryotic Translation Initiation Factor 4E Is a Feed-Forward Translational Coactivator of Transforming Growth Factor β Early Protransforming Events in Breast Epithelial Cells.
Q37629201	Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.
Q37848543	Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion
Q36830383	Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.
Q37046975	Eukaryotic initiation factor 2α phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanism
Q36144955	Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila
Q38717560	Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis.
Q37448155	Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation
Q34020233	Eukaryotic initiator tRNA: finely tuned and ready for action
Q29619569	Eukaryotic stress granules: the ins and outs of translation
Q36174741	Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex.
Q61455095	Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer
Q64260773	Eukaryotic translation initiation factor 3 subunit G promotes human colorectal cancer
Q38857306	Eukaryotic translation initiation factor 3, subunit C is overexpressed and promotes cell proliferation in human glioma U-87 MG cells
Q37536589	Eukaryotic translation initiation factor 3B accelerates the progression of esophageal squamous cell carcinoma by activating β-catenin signaling pathway
Q90498972	Eukaryotic translation initiation factor 6 overexpression plays a major role in the translational control of gallbladder cancer
Q39400409	Eukaryotic translation initiation factors and cancer
Q24339523	Eukaryotic translation initiation is controlled by cooperativity effects within ternary complexes of 4E-BP1, eIF4E, and the mRNA 5' cap
Q41699665	Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting
Q64252262	Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections
Q38663736	Evidence for eIF2α phosphorylation-independent effects of GSK2656157, a novel catalytic inhibitor of PERK with clinical implications
Q42253597	Evidence of direct complementary interactions between messenger RNAs and their cognate proteins
Q64212176	Evolution of eIF4E-Interacting Proteins
Q35891688	Evolution of translation initiation sequences using in vitro yeast ribosome display.
Q45781464	Evolutionary conserved motifs constrain the RNA structure organization of picornavirus IRES.
Q89682233	Expanding Role of Ubiquitin in Translational Control
Q56495932	Experience-dependent translational state defined by cell type-specific ribosome profiling
Q26770055	Exploiting tRNAs to Boost Virulence
Q58698129	Exploring the Impact of Single-Nucleotide Polymorphisms on Translation
Q58101002	Exploring the Role of AUG Triplets in Human Cap-Independent Translation Enhancing Elements
Q33949966	Exploring the selective constraint on the sizes of insertions and deletions in 5' untranslated regions in mammals
Q36545784	Expression and activity of eIF6 trigger malignant pleural mesothelioma growth in vivo.
Q41457737	Expression of human Hemojuvelin (HJV) is tightly regulated by two upstream open reading frames in HJV mRNA that respond to iron overload in hepatic cells.
Q36036183	Extensive allele-specific translational regulation in hybrid mice.
Q34410728	Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei
Q41083717	Extensive translation of circular RNAs driven by N6-methyladenosine
Q42774596	Extensive translational regulation of gene expression in an allopolyploid (Glycine dolichocarpa).
Q34264546	Extensive translatome remodeling during ER stress response in mammalian cells
Q54506429	F-box proteins elongate translation during stress recovery.
Q57753454	FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation
Q47862483	FXR1a-associated microRNP: A driver of specialized non-canonical translation in quiescent conditions
Q39683229	Facilitated leaky scanning and atypical ribosome shunting direct downstream translation initiation on the tricistronic S1 mRNA of avian reovirus
Q93031811	Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors
Q34420914	Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer
Q36103590	Fibroblasts from long-lived mutant mice exhibit increased autophagy and lower TOR activity after nutrient deprivation or oxidative stress
Q37678004	Fibrotic extracellular matrix activates a profibrotic positive feedback loop
Q35168282	Fifteen novel EIF2B1-5 mutations identified in Chinese children with leukoencephalopathy with vanishing white matter and a long term follow-up
Q48518399	Fluorescently-tagged human eIF3 for single-molecule spectroscopy
Q27696897	Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch
Q28592763	Four translation initiation pathways employed by the leaderless mRNA in eukaryotes
Q36065888	From cis-regulatory elements to complex RNPs and back
Q36124036	From immunobiology to β-cell biology: the changing perspective on type 1 diabetes
Q37961791	Function and detection of 5-methylcytosine in eukaryotic RNA.
Q46856027	Functional 5' UTR mRNA structures in eukaryotic translation regulation and how to find them
Q91775725	Functional Translatome Proteomics Reveal Converging and Dose-Dependent Regulation by mTORC1 and eIF2α
Q36101573	Functional advantages of dynamic protein disorder
Q42587564	Functional and direct interaction between the RNA binding protein HuD and active Akt1.
Q35252903	Functional and structural analysis of maize hsp101 IRES.
Q28482125	Functional and structural analysis of the internal ribosome entry site present in the mRNA of natural variants of the HIV-1
Q41974670	Functional characterization of the role of the N-terminal domain of the c/Nip1 subunit of eukaryotic initiation factor 3 (eIF3) in AUG recognition.
Q91828935	Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo
Q35379160	G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases
Q90029587	G-quadruplex located in the 5'UTR of the BAG-1 mRNA affects both its cap-dependent and cap-independent translation through global secondary structure maintenance
Q40103157	G3BP1 interacts directly with the FMDV IRES and negatively regulates translation.
Q33720257	GCN2 phosphorylates HIV-1 integrase and decreases HIV-1 replication by limiting viral integration.
Q37625365	GCN2-like eIF2α kinase manages the amino acid starvation response in Toxoplasma gondii
Q24324687	GTP-independent tRNA delivery to the ribosomal P-site by a novel eukaryotic translation factor
Q44794276	GTPase ROP2 binds and promotes activation of target of rapamycin, TOR, in response to auxin
Q42054269	Gemin5 promotes IRES interaction and translation control through its C-terminal region
Q38433117	Gemin5: A Multitasking RNA-Binding Protein Involved in Translation Control.
Q27693182	Gene expression regulation by upstream open reading frames and human disease
Q38371376	Gene function prediction using semantic similarity clustering and enrichment analysis in the malaria parasite Plasmodium falciparum
Q30002378	Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels
Q35060175	Genes associated with thermosensitive genic male sterility in rice identified by comparative expression profiling.
Q34394800	Genetic influences on translation in yeast
Q92135927	Genetic variation and function of the HIV-1 Tat protein
Q35754676	Genome-Wide Analysis of PAPS1-Dependent Polyadenylation Identifies Novel Roles for Functionally Specialized Poly(A) Polymerases in Arabidopsis thaliana.
Q33718812	Genome-Wide Translational Profiling by Ribosome Footprinting
Q35939590	Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells
Q92737473	Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer
Q24620643	Genome-wide annotation and quantitation of translation by ribosome profiling
Q34122513	Genome-wide assessment of differential roles for p300 and CBP in transcription regulation
Q28595650	Genome-wide gene expression and RNA half-life measurements allow predictions of regulation and metabolic behavior in Methanosarcina acetivorans
Q47115752	Genome-wide identification and differential analysis of translational initiation
Q36466647	Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress
Q90364715	Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during Drosophila development
Q34774432	Genome-wide profiling of human cap-independent translation-enhancing elements
Q36354889	Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
Q38013735	Germ granules and the control of mRNA translation.
Q90391353	Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita
Q89865167	Global analysis of LARP1 translation targets reveals tunable and dynamic features of 5' TOP motifs
Q39145106	Global and local mechanisms sustain axonal proteostasis of transmembrane proteins.
Q34296372	Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution
Q28238103	Global quantification of mammalian gene expression control
Q33874396	Global signatures of protein and mRNA expression levels
Q92643357	Global translational repression induced by iron deficiency in yeast depends on the Gcn2/eIF2α pathway
Q45024786	Glutamate-dependent translational control in cultured Bergmann glia cells: eIF2α phosphorylation.
Q26783363	Glutamatergic Transmission: A Matter of Three
Q90516042	Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis
Q42115920	Granules harboring translationally active mRNAs provide a platform for P-body formation following stress.
Q21559400	Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3
Q26995758	Growing with the wind. Ribosomal protein hydroxylation and cell growth
Q27929828	Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae.
Q33897677	HDAC2 promotes eIF4E sumoylation and activates mRNA translation gene specifically
Q89039556	HIF Oxygen Sensing Pathways in Lung Biology
Q38273477	HIV-1 replication and latency are regulated by translational control of cyclin T1
Q35092875	HIV-1 transcripts use IRES-initiation under conditions where Cap-dependent translation is restricted by poliovirus 2A protease
Q30314863	HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins
Q92478425	Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer
Q64068138	Heat shock in C. elegans induces downstream of gene transcription and accumulation of double-stranded RNA
Q36015026	Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis
Q35762918	Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation
Q34362367	Herpes Simplex Virus is Akt-ing in translational control
Q92255602	Herpesviruses and the Unfolded Protein Response
Q88562596	Heterogeneity and specialized functions of translation machinery: from genes to organisms
Q41612643	Heterogeneous nuclear ribonucleoprotein (hnRNP) L promotes DNA damage-induced cell apoptosis by enhancing the translation of p53.
Q38910395	High Level of Nonsynonymous Changes in Common Bean Suggests That Selection under Domestication Increased Functional Diversity at Target Traits
Q51368667	High expression of cytoplasmic polyadenylation element-binding protein 4 correlates with poor prognosis of patients with colorectal cancer.
Q27934600	High-resolution view of the yeast meiotic program revealed by ribosome profiling
Q26829672	Homeostatic plasticity at the Drosophila neuromuscular junction
Q38649243	Homeostatic regulation of trace mineral transport by ubiquitination of membrane transporters
Q38048858	Host detection of pathogen-induced translational inhibition: a new pathogen-specific branch of the innate immune system?
Q52723247	Host translational control of a polydnavirus, Cotesia plutellae bracovirus, by sequestering host eIF4A to prevent formation of a translation initiation complex.
Q47782255	How Ribosomes Translate Cancer.
Q40920812	How do miRNAs mediate translational repression?
Q52326256	Hrp48 and eIF3d contribute to msl-2 mRNA translational repression.
Q39753679	HuD stimulates translation via eIF4A.
Q50209147	Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
Q26752742	Human Cytomegalovirus Strategies to Maintain and Promote mRNA Translation
Q42816046	Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1.
Q50990310	Human Keratinocyte Differentiation Requires Translational Control by the eIF2α Kinase GCN2.
Q33747830	Human SHBG mRNA translation is modulated by alternative 5'-non-coding exons 1A and 1B.
Q90191925	Human cytomegalovirus pTRS1 stimulates cap-independent translation
Q39330119	Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation
Q38732490	Hydroxylation and translational adaptation to stress: some answers lie beyond the STOP codon.
Q55419613	Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel-Lindau-Deficient Renal Cancer.
Q35237075	Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum.
Q49569525	Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo
Q42074359	IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex
Q34679101	IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans.
Q28594198	IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth
Q42134027	IRES-Dependent Translational Control during Virus-Induced Endoplasmic Reticulum Stress and Apoptosis
Q35868482	IRES-dependent translated genes in fungi: computational prediction, phylogenetic conservation and functional association.
Q36246640	IRES-dependent translation of egr2 is induced under inflammatory conditions
Q90028527	IRES-mediated cap-independent translation, a path leading to hidden proteome
Q35077557	IRES-mediated translation of membrane proteins and glycoproteins in eukaryotic cell-free systems
Q33600648	IRESite--a tool for the examination of viral and cellular internal ribosome entry sites
Q37360742	Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.
Q90673447	Identification of a 57S translation complex containing closed-loop factors and the 60S ribosome subunit
Q37241748	Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step
Q53282058	Identification of a new isoform of eEF2 whose phosphorylation is required for completion of cell division in sea urchin embryos.
Q33789786	Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery
Q36295318	Identification of global alteration of translational regulation in glioma in vivo
Q39770544	Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation
Q64104089	Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming
Q38420747	Identifying novel targets of oncogenic EGF receptor signaling in lung cancer through global phosphoproteomics.
Q35673642	Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin
Q38041908	Imaging translation in single cells using fluorescent microscopy
Q36730754	Imaging viral RNA using multiply labeled tetravalent RNA imaging probes in live cells
Q34808585	Immediate translation of Formin DIAPH1 mRNA after its exiting the nucleus is required for its perinuclear localization in fibroblasts
Q35864120	Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens
Q89550573	Impact of Prevalence Ratios of Chondroitin Sulfate (CS)- 4 and -6 Isomers Derived from Marine Sources in Cell Proliferation and Chondrogenic Differentiation Processes
Q97424773	Impact of mRNA chemistry and manufacturing process on innate immune activation
Q64092516	Impaired EIF2S3 function associated with a novel phenotype of X-linked hypopituitarism with glucose dysregulation
Q42267347	Impaired binding of standard initiation factors eIF3b, eIF4G and eIF4B to domain V of the live-attenuated coxsackievirus B3 Sabin3-like IRES--alternatives for 5'UTR-related cardiovirulence mechanisms
Q35864966	Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases
Q24306324	Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth
Q52729625	Importance of ERK1/2 in Regulation of Protein Translation during Oocyte Meiosis.
Q38633663	Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation.
Q35659976	In vivo and transcriptome-wide identification of RNA binding protein target sites
Q40343377	In-cell SHAPE uncovers dynamic interactions between the untranslated regions of the foot-and-mouth disease virus RNA.
Q30391587	Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice
Q90241057	Induction of immunoproteasomes in porcine kidney (PK)-15 cells by interferon-γ and tumor necrosis factor-α
Q59127567	Infection with flaviviruses requires BCLXL for cell survival
Q38657137	Inferring Methionine Sulfoxidation and serine Phosphorylation crosstalk from Phylogenetic analyses
Q28305723	Inflammatory conditions induce IRES-dependent translation of cyp24a1
Q36368265	Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma.
Q33829976	Inhibition of ERK1/2 Restores GSK3β Activity and Protein Synthesis Levels in a Model of Tuberous Sclerosis
Q90320013	Inhibition of MUC1-C regulates metabolism by AKT pathway in esophageal squamous cell carcinoma
Q36573991	Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin
Q47236736	Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice
Q35763016	Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence.
Q34120213	Inhibition of encephalomyocarditis virus and poliovirus replication by quinacrine: implications for the design and discovery of novel antiviral drugs
Q39326047	Inhibition of mTOR kinase as a therapeutic target for acute myeloid leukemia
Q93017718	Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer
Q41293411	Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury
Q47633362	Inhibition of translation initiation factor eIF4A is required for apoptosis mediated by Microplitis bicoloratus bracovirus
Q36344534	Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression
Q92709172	Inhibitory interneurons mediate autism-associated behaviors via 4E-BP2
Q35534370	Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome
Q39648806	Initiation of translation at an upstream non-AUG codon accounting for N-terminally extended minor forms of recombinant proteins expressed in insect cells
Q26779741	Insights into Eukaryotic Translation Initiation from Mass Spectrometry of Macromolecular Protein Assemblies
Q33710467	Insights into the architecture of the eIF2Bα/β/δ regulatory subcomplex
Q90294261	Insulin action on protein synthesis and its association with eIF5A expression and hypusination
Q37072648	Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism
Q37122759	Interaction between 25S rRNA A loop and eukaryotic translation initiation factor 5B promotes subunit joining and ensures stringent AUG selection
Q59351754	Interaction of rRNA with mRNA and tRNA in Translating Mammalian Ribosome: Functional Implications in Health and Disease
Q91617422	Intermittent bolus feeding promotes greater lean growth than continuous feeding in a neonatal piglet model
Q36443702	Internal translation initiation from HIV-1 transcripts is conferred by a common RNA structure
Q37645644	Interrelation between protein synthesis, proteostasis and life span
Q39088851	Intersections of post-transcriptional gene regulatory mechanisms with intermediary metabolism
Q55044473	Intracellular Regulome Variability Along the Organ of Corti: Evidence, Approaches, Challenges, and Perspective.
Q93020284	Intragenic regulation of SOCS3 isoforms
Q39066009	Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain
Q90160976	Inverted translational control of eukaryotic gene expression by ribosome collisions
Q38339133	Involvement of Arabidopsis RACK1 in protein translation and its regulation by abscisic acid
Q41269902	Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development.
Q92072498	Involvement of the eIF2α Kinase GCN2 in UV-B Responses
Q92121725	In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation
Q37164919	Iron depletion increases manganese uptake and potentiates apoptosis through ER stress
Q39433508	Key contribution of CPEB4-mediated translational control to cancer progression
Q36545515	Key contribution of eIF4H-mediated translational control in tumor promotion.
Q30616580	Kinetic pathway of 40S ribosomal subunit recruitment to hepatitis C virus internal ribosome entry site.
Q38543715	Knockdown of eukaryotic translation initiation factor 4E suppresses cell growth and invasion, and induces apoptosis and cell cycle arrest in a human lung adenocarcinoma cell line
Q38952061	L protease from foot and mouth disease virus confers eIF2-independent translation for mRNAs bearing picornavirus IRES.
Q47774083	L-Serine: a Naturally-Occurring Amino Acid with Therapeutic Potential
Q43763036	L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system
Q41412927	LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation
Q37124577	LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction
Q47290550	La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.
Q90284967	Length and secondary structure of the 5' non-coding regions of mouse p53 mRNA transcripts - mouse as a model organism for p53 gene expression studies
Q41901325	Length variants of the 5' untranslated region of p53 mRNA and their impact on the efficiency of translation initiation of p53 and its N-truncated isoform ΔNp53
Q38670994	Leucine Differentially Regulates Gene-Specific Translation in Mouse Skeletal Muscle
Q37142401	Leucine pulses enhance skeletal muscle protein synthesis during continuous feeding in neonatal pigs
Q98613805	Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span
Q34197008	Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans
Q49586225	Light-activated control of translation by enzymatic covalent mRNA labeling
Q47832962	Light-inducible activation of target mRNA translation in mammalian cells.
Q35655644	Light-regulated translational control of circadian behavior by eIF4E phosphorylation
Q48155681	Linking Cancer Cachexia-Induced Anabolic Resistance to Skeletal Muscle Oxidative Metabolism.
Q41211794	Local RNA flexibility perturbation of the IRES element induced by a novel ligand inhibits viral RNA translation
Q34199867	Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.
Q34359294	Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome
Q42242989	Long-term in vivo imaging of translated RNAs for gene therapy.
Q38977612	Long-term memory consolidation: The role of RNA-binding proteins with prion-like domains
Q34227565	Loss of 4E-BP1 function induces EMT and promotes cancer cell migration and invasion via cap-dependent translational activation of snail
Q47628356	Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects
Q47647133	Loss of eIF4E phosphorylation engenders depression-like behaviors via selective mRNA translation.
Q34035639	Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis
Q35304085	Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis
Q26864403	Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus
Q58748104	Lso2 is a conserved ribosome-bound protein required for translational recovery in yeast
Q91721378	Lupus-associated endogenous retroviral LTR polymorphism and epigenetic imprinting promote HRES-1/RAB4 expression and mTOR activation
Q93079012	MAPK- and glycogen synthase kinase 3-mediated phosphorylation regulates the DEAD-box protein modulator Gle1 for control of stress granule dynamics
Q90210539	MNK-eIF4E signalling is a highly conserved mechanism for sensory neuron axonal plasticity: evidence from Aplysia californica
Q37524253	MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas
Q47649072	MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma
Q47586759	MRF Family Genes Are Involved in Translation Control, Especially under Energy-Deficient Conditions, and Their Expression and Functions Are Modulated by the TOR Signaling Pathway.
Q34028756	MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice
Q39372689	MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors
Q38981600	Magnesium-dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction
Q34422487	Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response
Q37943416	Mammalian TOR signaling to the AGC kinases
Q90126017	Mammalian alternative translation initiation is mostly nonadaptive
Q38254758	Manipulation of host pathways by human cytomegalovirus: insights from genome-wide studies
Q36539764	Many lncRNAs, 5'UTRs, and pseudogenes are translated and some are likely to express functional proteins
Q38122222	Many roads from mTOR to eIF4F.
Q46942412	Mapping the translation initiation landscape of an S. cerevisiae gene using fluorescent proteins
Q64950497	Maternal corticotropin-releasing hormone is associated with LEP DNA methylation at birth and in childhood: an epigenome-wide study in Project Viva.
Q92891230	Measuring mRNA translation in neuronal processes and somata by tRNA-FRET
Q90192287	Mechanical Forces and Their Effect on the Ribosome and Protein Translation Machinery
Q89823740	Mechanical Regulation of Protein Translation in the Cardiovascular System
Q35636275	Mechanism of cytoplasmic mRNA translation
Q55091565	Mechanism of translation control of the alternative Drosophila melanogaster Voltage Dependent Anion-selective Channel 1 mRNAs.
Q26852197	Mechanisms and implications of programmed translational frameshifting
Q33665807	Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
Q38183979	Mechanisms of translation control underlying long-lasting synaptic plasticity and the consolidation of long-term memory.
Q37739649	Mechanisms of translational regulation in synaptic plasticity
Q89355484	Mechanistic Insights into MicroRNA-Mediated Gene Silencing
Q64075806	Mechanistic Target of Rapamycin Pathway in Epileptic Disorders
Q34544246	Mechanistic insights into mammalian stress granule dynamics.
Q37317515	Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress
Q39707338	Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth
Q35673328	Methylome Analysis in Chickens Immunized with Infectious Laryngotracheitis Vaccine
Q37036389	Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster
Q45875338	MicroRNA-based therapeutics in cardiovascular disease: screening and delivery to the target
Q37726449	MicroRNA-mediated gene silencing
Q94547397	Mitochondrial Quality Control Governed by Ubiquitin
Q36650395	Mitochondrial Sulfide Quinone Oxidoreductase Prevents Activation of the Unfolded Protein Response in Hydrogen Sulfide
Q36553656	Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis
Q37061433	Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A.
Q60228312	Modular 5'-UTR hexamers for context-independent tuning of protein expression in eukaryotes
Q38724763	Modulation of Intrinsically Disordered Protein Function by Post-translational Modifications
Q35912441	Modulation of gurken translation by insulin and TOR signaling in Drosophila
Q36509018	Modulation of inflammatory gene expression by the ribotoxin deoxynivalenol involves coordinate regulation of the transcriptome and translatome
Q37672756	Modulation of mTOR signaling as a strategy for the treatment of Pompe disease
Q36790304	Molecular Analysis of RNA-RNA Interactions between 5' and 3' Untranslated Regions during the Initiation of Translation of a Cardiovirulent and a Live-Attenuated Coxsackievirus B3 Strains
Q38908313	Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2α Phosphorylation in Caenorhabditis elegans
Q27680550	Molecular architecture of a eukaryotic translational initiation complex
Q27934341	Molecular architecture of the 40S⋅eIF1⋅eIF3 translation initiation complex
Q34626912	Molecular biology. The eukaryotic ribosome
Q42008913	Molecular biology: Entry signals control development
Q33797455	Molecular cloning, characterization and expression analysis of Frizzled 6 in the small intestine of pigs (Sus scrofa)
Q37170533	Molecular control of the amount, subcellular location, and activity state of translation elongation factor 2 in neurons experiencing stress
Q41888376	Molecular dynamics simulation of the allosteric regulation of eIF4A protein from the open to closed state, induced by ATP and RNA substrates
Q33649025	Molecular markers of paragangliomas/pheochromocytomas
Q35909996	Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1
Q37602836	Molecular signal networks and regulating mechanisms of the unfolded protein response
Q61801081	Molecular targets for modulating the protein translation vital to proteostasis and neuron degeneration in Parkinson's disease
Q33967297	Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiation
Q47142081	Monitoring the Temporal Expression of Genes Involved in Ochratoxin A Production of Aspergillus carbonarius under the Influence of Temperature and Water Activity
Q57784972	Montelukast enhances cytocidal effects of carfilzomib in multiple myeloma by inhibiting mTOR pathway
Q52715671	Montelukast inhibits hypoxia inducible factor-1α translation in prostate cancer cells.
Q39028088	More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer.
Q26778121	Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses
Q34883412	Multilayer regulatory mechanisms control cleavage factor I proteins in filamentous fungi.
Q54115773	Multiple Transceptors for Macro- and Micro-Nutrients Control Diverse Cellular Properties Through the PKA Pathway in Yeast: A Paradigm for the Rapidly Expanding World of Eukaryotic Nutrient Transceptors Up to Those in Human Cells.
Q34807963	Multiple mechanisms collaborate to repress nanos translation in the Drosophila ovary and embryo
Q90103694	Multisite rate control analysis identifies ribosomal scanning as the sole high-capacity/low-flux-control step in mRNA translation
Q46360777	Muscle metabolic alterations induced by genetic ablation of 4E-BP1 and 4E-BP2 in response to diet-induced obesity
Q38624981	Mutations in eIF5B confer thermosensitive and pleiotropic phenotypes via translation defects in Arabidopsis thaliana
Q37031640	Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers
Q24337939	N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency
Q38239267	N-terminomics and proteogenomics, getting off to a good start
Q33741117	N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density
Q50074810	N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
Q36466338	NAT1/DAP5/p97 and atypical translational control in the Drosophila Circadian Oscillator
Q42330675	NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer
Q35843515	Nanopore detachment kinetics of poly(A) binding proteins from RNA molecules reveals the critical role of C-terminus interactions
Q45558582	Natural occurrence and physiological role of a truncated eIF4E in the porcine endometrium during implantation
Q92646327	Ncl1-mediated metabolic rewiring critical during metabolic stress
Q28579871	New Hierarchical Phosphorylation Pathway of the Translational Repressor eIF4E-binding Protein 1 (4E-BP1) in Ischemia-Reperfusion Stress
Q48506350	New Insights Into the Role of mTOR Signaling in the Cardiovascular System.
Q33853235	New frontiers in translational control of the cancer genome
Q40948168	New insights into 4E-BP1-regulated translation in cancer progression and metastasis
Q37940386	No-go decay: a quality control mechanism for RNA in translation
Q47690525	Non-AUG translation: a new start for protein synthesis in eukaryotes
Q38692480	Non-canonical Translation in Plant RNA Viruses
Q96609280	Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition
Q26991938	Non-transcriptional interactions of Hox proteins: inventory, facts, and future directions
Q34485116	Noncytotoxic Inhibition of Viral Infection through eIF4F-Independent Suppression of Translation by 4EGi-1
Q35118819	Nonsense-mediated mRNA decay immunity can help identify human polycistronic transcripts
Q55068343	Novel C-4 heteroaryl 13-cis-retinamide Mnk/AR degrading agents inhibit cell proliferation and migration and induce apoptosis in human breast and prostate cancer cells and suppress growth of MDA-MB-231 human breast and CWR22Rv1 human prostate tumor x
Q51731770	Novel alleles of rice eIF4G generated by CRISPR/Cas9-targeted mutagenesis confer resistance to Rice tungro spherical virus.
Q27939840	Novel insights into the architecture and protein interaction network of yeast eIF3
Q38433959	Novel insights into the effect of nitrogen on storage protein biosynthesis and protein body development in wheat caryopsis.
Q37197950	Novel mechanism of cytokine-induced disruption of epithelial barriers: Janus kinase and protein kinase D-dependent downregulation of junction protein expression
Q37785105	Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases
Q57077664	Nucleotide recognition by the initiation factor aIF5B: Free energy simulations of a neoclassical GTPase
Q34075503	Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34.
Q37712052	Nutrient signaling in protein homeostasis: an increase in quantity at the expense of quality
Q42146110	Nutrient/TOR-dependent regulation of RNA polymerase III controls tissue and organismal growth in Drosophila.
Q35787711	Nutritional and hormonal regulation of the TOR effector 4E-binding protein (4E-BP) in the mosquito Aedes aegypti
Q43814314	Nutritional stress affects an atypical cap-binding protein in Leishmania
Q92357932	Nutritional stress targets LeishIF4E-3 to storage granules that contain RNA and ribosome components in Leishmania
Q39193091	OASL1 inhibits translation of the type I interferon-regulating transcription factor IRF7.
Q34292237	On the Diversification of the Translation Apparatus across Eukaryotes
Q39114297	Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress.
Q90721907	Oncogenic kinases and perturbations in protein synthesis machinery and energetics in neoplasia
Q39137817	One-step nucleic acid amplification (OSNA) for intraoperative evaluation of sentinel lymph node status in breast cancer: a comparative study between CK19 protein expression and CK19 mRNA level in primary tumors and lymph node metastasis.
Q39002246	Optimisation of the mRNA secondary structure to improve the expression of interleukin-24 (IL-24) in Escherichia coli
Q92002973	Optimization of 5' Untranslated Region of Modified mRNA for Use in Cardiac or Hepatic Ischemic Injury
Q38986620	Optimization of PAR-CLIP for transcriptome-wide identification of binding sites of RNA-binding proteins
Q88172857	Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA
Q35627819	Optimization of translation profiles enhances protein expression and solubility
Q35368205	Our changing view of the genomic landscape of cancer
Q39185396	Overexpressed-eIF3I interacted and activated oncogenic Akt1 is a theranostic target in human hepatocellular carcinoma
Q38708764	Overexpression of CPEB4 in glioma indicates a poor prognosis by promoting cell migration and invasion
Q37631808	Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation
Q37336923	Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation
Q54308363	Overexpression of eukaryotic initiation factor 5 rescues the translational defect of tpk1w in a manner that necessitates a novel phosphorylation site.
Q57292453	Overlapping motifs on the herpes viral proteins ICP27 and ORF57 mediate interactions with the mRNA export adaptors ALYREF and UIF
Q43294355	Oxidative stress perturbs cell proliferation in human K562 cells by modulating protein synthesis and cell cycle.
Q61800952	Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation
Q47177113	Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B.
Q57124052	PAINTing translation
Q47298405	PAR-CLIP for Discovering Target Sites of RNA-Binding Proteins
Q42143384	PAR-CLIP: A Method for Transcriptome-Wide Identification of RNA Binding Protein Interaction Sites
Q40124899	PD-1 Checkpoint Blockade in Combination with an mTOR Inhibitor Restrains Hepatocellular Carcinoma Growth Induced by Hepatoma Cell-Intrinsic PD-1.
Q37688853	PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells.
Q38861201	PHYSIOLOGY AND ENDOCRINOLOGY SYMPOSIUM: Roles for insulin-supported skeletal muscle growth.
Q48284853	PKA-dependent phosphorylation of ribosomal protein S6 does not correlate with translation efficiency in striatonigral and striatopallidal medium-sized spiny neurons
Q51072666	PKR activation and eIF2α phosphorylation mediate human globin mRNA splicing at spliceosome assembly.
Q37310632	PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease
Q91973677	PKZ, a Fish-Unique eIF2α Kinase Involved in Innate Immune Response
Q42058506	PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz.
Q92310282	PROTACs: great opportunities for academia and industry
Q38866978	PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas
Q48204069	PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs.
Q93185186	Paip1 overexpression is involved in the progression of gastric cancer and predicts shorter survival of diagnosed patients
Q53255717	Pancreatic tumours escape from translational control through 4E-BP1 loss.
Q42144710	Pbp1 is involved in Ccr4- and Khd1-mediated regulation of cell growth through association with ribosomal proteins Rpl12a and Rpl12b
Q92815846	Perception of double-stranded RNA in plant antiviral immunity
Q37137491	Pervasive isoform-specific translational regulation via alternative transcription start sites in mammals.
Q97568978	Phenotypic effects of paralogous ribosomal proteins bL31A and bL31B in E. coli
Q39128991	Phosphatidic acid: biosynthesis, pharmacokinetics, mechanisms of action and effect on strength and body composition in resistance-trained individuals.
Q45858586	Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
Q24310482	Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate
Q33492309	Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response
Q37538574	Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival
Q34719370	Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation
Q34123406	Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.
Q37162273	Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.
Q41894289	Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis
Q34182794	Phosphorylation of eukaryotic initiation factor-2α promotes the extracellular survival of obligate intracellular parasite Toxoplasma gondii
Q41579911	Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress
Q38823597	Physiological and pathophysiological role of nonsense-mediated mRNA decay
Q35709132	Phytochrome regulates translation of mRNA in the cytosol
Q38330880	Picornavirus IRES elements: RNA structure and host protein interactions.
Q90403574	Pleiotropic Effects of mTOR and Autophagy During Development and Aging
Q51747268	Pleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas.
Q35517170	Poly(A) binding protein 1 enhances cap-independent translation initiation of neurovirulence factor from avian herpesvirus
Q33842516	Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.
Q41874584	Poly(A)-binding protein facilitates translation of an uncapped/nonpolyadenylated viral RNA by binding to the 3' untranslated region
Q50107198	Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA.
Q40856139	Polypyrimidine tract-binding protein binds to the 5' untranslated region of the mouse mammary tumor virus mRNA and stimulates cap-independent translation initiation
Q36917797	Polysome Profiling Links Translational Control to the Radioresponse of Glioblastoma Stem-like Cells
Q42738454	Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale
Q37736003	Porcine Reproductive and Respiratory Syndrome Virus Infection Induces Stress Granule Formation Depending on Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK) in MARC-145 Cells
Q59358844	Porcine Reproductive and Respiratory Syndrome Virus Infection Induces both eIF2α Phosphorylation-Dependent and -Independent Host Translation Shutoff
Q36628432	Positional proteomics reveals differences in N-terminal proteoform stability
Q34175183	Post-transcriptional RNA regulons affecting cell cycle and proliferation
Q39436212	Post-transcriptional control of gene expression following stress: the role of RNA-binding proteins
Q38325596	Posttranscriptional control of photosynthetic mRNA decay under stress conditions requires 3' and 5' untranslated regions and correlates with differential polysome association in rice
Q36722453	Posttranscriptional methylation of transfer and ribosomal RNA in stress response pathways, cell differentiation, and cancer
Q37134683	Potential Metabolic Biomarkers to Identify Interstitial Lung Abnormalities
Q26799485	Potential extra-ribosomal functions of ribosomal proteins in Saccharomyces cerevisiae
Q40090965	Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis
Q90041936	Presence of protein production enhancers results in significantly higher methanol-induced protein production in Pichia pastoris
Q42364710	Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release
Q37863285	Processive ubiquitin chain formation by the anaphase-promoting complex.
Q28550947	Production of Infectious Dengue Virus in Aedes aegypti Is Dependent on the Ubiquitin Proteasome Pathway
Q35817942	Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR)
Q33845661	Promiscuity in post-transcriptional control of gene expression: Drosophila sex-lethal and its regulatory partnerships
Q42777637	Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward.
Q28550953	Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent Infection
Q27333486	Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2
Q42324571	Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress
Q42369948	Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity
Q39246100	Protein phosphatase 2A (PP2A)-specific ubiquitin ligase MID1 is a sequence-dependent regulator of translation efficiency controlling 3-phosphoinositide-dependent protein kinase-1 (PDPK-1).
Q37095424	Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1)
Q34082958	Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms
Q50066488	Protein translation in the nucleus accumbens is dysregulated during cocaine withdrawal and required for expression of incubation of cocaine craving.
Q92252377	Protein-RNA interactions important for Plasmodium transmission
Q36346212	Proteogenomic analysis reveals alternative splicing and translation as part of the abscisic acid response in Arabidopsis seedlings.
Q38954697	Proteome complexity and the forces that drive proteome imbalance.
Q33899503	Proteomic analysis of ribosomes: translational control of mRNA populations by glycogen synthase GYS1.
Q47836573	Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions.
Q33855707	Proteomic quantification and site-mapping of S-nitrosylated proteins using isobaric iodoTMT reagents
Q42378347	Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention
Q99350413	Proteomics provides insights into the inhibition of Chinese hamster V79 cell proliferation in the deep underground environment
Q91012681	Psp2, a novel regulator of autophagy that promotes autophagy-related protein translation
Q27674307	Pub1p C-Terminal RRM Domain Interacts with Tif4631p through a Conserved Region Neighbouring the Pab1p Binding Site
Q35672298	Punctuated cyclin synthesis drives early embryonic cell cycle oscillations
Q28084341	Quality control systems in cardiac aging
Q38196653	Quality control: Is there quality control of localized mRNAs?
Q36668847	Quantifying RNA-protein interactions in situ using modified-MTRIPs and proximity ligation
Q58548552	Quantifying Single mRNA Translation Kinetics in Living Cells
Q59327243	Quantifying post-transcriptional regulation in the development of Drosophila melanogaster
Q99595200	Quantifying the dynamics of IRES and cap translation with single-molecule resolution in live cells
Q35206433	Quantifying the effect of ribosomal density on mRNA stability
Q41834634	Quantitative Nucleotide Level Analysis of Regulation of Translation in Response to Depolarization of Cultured Neural Cells
Q35234645	Quantitative analysis of mammalian translation initiation sites by FACS-seq
Q35130077	Quantitative profiling of initiating ribosomes in vivo
Q49178955	Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
Q34667720	Quantitative proteomics reveals a "poised quiescence" cellular state after triggering the DNA replication origin activation checkpoint
Q85822839	Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal
Q28511972	RACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiency
Q26823908	RAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disorders
Q47313248	RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response
Q54212051	RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence.
Q92484228	RGG-motif self-association regulates eIF4G-binding translation repressor protein Scd6
Q91173398	RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity
Q39089972	RNA G-quadruplexes and their potential regulatory roles in translation.
Q47907249	RNA Nuclear Export: From Neurological Disorders to Cancer
Q38019544	RNA binding protein/RNA element interactions and the control of translation
Q37711032	RNA localization in neurite morphogenesis and synaptic regulation: current evidence and novel approaches
Q91713119	RNA modifications regulating cell fate in cancer
Q29615182	RNA processing and its regulation: global insights into biological networks
Q35159261	RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation
Q34085158	RNA sequencing: from tag-based profiling to resolving complete transcript structure
Q39603230	RNA targets of wild-type and mutant FET family proteins
Q37375354	RNA-binding proteins impacting on internal initiation of translation
Q40919209	RNA-binding proteins regulate the expression of the immune activating ligand MICB.
Q38542770	RNA-protein interaction methods to study viral IRES elements.
Q34047337	RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.
Q45095625	RNAs: regulators of bacterial virulence
Q42727298	RNase-assisted RNA chromatography
Q27490486	RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs
Q35634079	RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth
Q37317329	RSK-mediated down-regulation of PDCD4 is required for proliferation, survival, and migration in a model of triple-negative breast cancer
Q38820203	Rapamycin modulation of p70 S6 kinase signaling inhibits Rift Valley fever virus pathogenesis
Q54351819	Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.
Q91877813	Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity
Q27349418	Re-localization of cellular protein SRp20 during poliovirus infection: bridging a viral IRES to the host cell translation apparatus
Q48610359	Real-time quantification of single RNA translation dynamics in living cells
Q36967425	Receptor for activated C-kinase (RACK1) homolog Cpc2 facilitates the general amino acid control response through Gcn2 kinase in fission yeast
Q42146692	Recognition of viral RNA stem-loops by the tandem double-stranded RNA binding domains of PKR.
Q26861563	Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond
Q39405750	Recruitment of host translation initiation factor eIF4G by the Vaccinia Virus ssDNA-binding protein I3.
Q51820369	Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.
Q90161291	Reduced EGFR Level in eIF2α PhosphorylationDeficient Hepatocytes Is Responsible for Susceptibility to Oxidative Stress
Q33655715	Reductions in laminin beta2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose
Q37811200	Regulation and deregulation of mRNA translation during myeloid maturation
Q36281864	Regulation of PACT-Mediated Protein Kinase Activation by the OV20.0 Protein of Orf Virus
Q38852157	Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins.
Q38256715	Regulation of TFEB and V-ATPases by mTORC1.
Q38704999	Regulation of Tacaribe Mammarenavirus Translation: Positive 5' and Negative 3' Elements and Role of Key Cellular Factors
Q35669187	Regulation of Torpor in the Gray Mouse Lemur: Transcriptional and Translational Controls and Role of AMPK Signaling
Q38084833	Regulation of Translation Initiation under Biotic and Abiotic Stresses
Q35810804	Regulation of amino acid, nucleotide, and phosphate metabolism in Saccharomyces cerevisiae
Q60048594	Regulation of cellular gene expression by nanomaterials
Q41888766	Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.
Q55041787	Regulation of filial imprinting and structural plasticity by mTORC1 in newborn chickens.
Q26771382	Regulation of global and specific mRNA translation by the mTOR signaling pathway
Q33497920	Regulation of host translational machinery by African swine fever virus
Q39241455	Regulation of human immunodeficiency virus type 1 (HIV-1) mRNA translation.
Q38190098	Regulation of interferon-dependent mRNA translation of target genes
Q46818543	Regulation of mRNA Translation in Neurons-A Matter of Life and Death
Q38034202	Regulation of mRNA translation by signaling pathways
Q26764871	Regulation of mTORC1 by growth factors, energy status, amino acids and mechanical stimuli at a glance
Q40998372	Regulation of membrane protein degradation by starvation-response pathways
Q34239574	Regulation of polysome assembly on the endoplasmic reticulum by a coiled-coil protein, p180.
Q37797917	Regulation of protein synthesis and the role of eIF3 in cancer
Q30983909	Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin
Q42778545	Regulation of ubiquitin chain initiation to control the timing of substrate degradation.
Q38153592	Regulatory crosstalk within the mammalian unfolded protein response
Q58106909	Regulatory discrimination of mRNAs by FMRP controls mouse adult neural stem cell differentiation
Q37064617	Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates
Q26995087	Remote control of gene function by local translation
Q88264776	Removing 4E-BP Enables Synapses to Refine without Postsynaptic Activity
Q41048721	Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain
Q34543709	Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders
Q33851463	Repeat associated non-ATG translation initiation: one DNA, two transcripts, seven reading frames, potentially nine toxic entities!
Q89068599	Repeat-Associated Non-ATG Translation in Neurological Diseases
Q92607005	Repeat-Associated Non-ATG Translation: Molecular Mechanisms and Contribution to Neurological Disease
Q37576366	Repeated Exposure to D-Amphetamine Decreases Global Protein Synthesis and Regulates the Translation of a Subset of mRNAs in the Striatum
Q39139050	Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma
Q30853501	Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice
Q40147182	Requirement for eukaryotic translation initiation factors in cap-independent translation differs between bipartite genomic RNAs of red clover necrotic mosaic virus
Q34936880	Requirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis by hypertonic conditions and mTOR inhibition
Q39236670	Requirements for eIF4A and eIF2 during translation of Sindbis virus subgenomic mRNA in vertebrate and invertebrate host cells.
Q28540038	Resistance to mTOR kinase inhibitors in lymphoma cells lacking 4EBP1
Q100166036	Response of EIF2AK4 (GCN2) to amino acid deficiency
Q47124339	Response of Turkey Muscle Satellite Cells to Thermal Challenge. II. Transcriptome Effects in Differentiating Cells
Q35772025	Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain
Q35738555	Resveratrol up-regulates AMPA receptor expression via AMP-activated protein kinase-mediated protein translation
Q36572805	Reversible RNA adenosine methylation in biological regulation
Q34979422	Reversible and rapid transfer-RNA deactivation as a mechanism of translational repression in stress.
Q35758763	Ribavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia
Q36370867	RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes
Q37208276	Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation
Q36790234	Ribosomal Initiation Complex Assembly within the Wild-Strain of Coxsackievirus B3 and Live-Attenuated Sabin3-like IRESes during the Initiation of Translation
Q58587039	Ribosomal protein eL24, involved in two intersubunit bridges, stimulates translation initiation and elongation
Q38174514	Ribosomal proteins as novel players in tumorigenesis
Q41828740	Ribosome Footprint Profiling of Translation throughout the Genome
Q59793283	Ribosome Profiling Reveals HSP90 Inhibitor Effects on Stage-Specific Protein Synthesis in
Q64974388	Ribosome elongating footprints denoised by wavelet transform comprehensively characterize dynamic cellular translation events.
Q29617505	Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes
Q54998021	Ribosome profiling reveals changes in translational status of soybean transcripts during immature cotyledon development.
Q39169184	Ribosome profiling reveals dynamic translational landscape in maize seedlings under drought stress.
Q34435177	Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes
Q41845109	Ribosome profiling reveals post-transcriptional buffering of divergent gene expression in yeast.
Q38615964	Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress
Q44759418	Ribosome profiling: new views of translation, from single codons to genome scale
Q27319572	Ribosome synthesis and MAPK activity modulate ionizing radiation-induced germ cell apoptosis in Caenorhabditis elegans
Q55025357	Ribosome-dependent conformational flexibility changes and RNA dynamics of IRES domains revealed by differential SHAPE.
Q28591034	Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning
Q36512422	Ribosomes take control
Q34454066	Ribosomopathies: mechanisms of disease
Q88670916	Roadblocks and resolutions in eukaryotic translation
Q37099012	Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor
Q34358701	Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders
Q37548069	Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer Progression
Q91399335	Role of Paip1 on angiogenesis and invasion in pancreatic cancer
Q26999339	Role of amino acid transporters in amino acid sensing
Q47654911	Role of hypoxia in Diffuse Large B-cell Lymphoma: Metabolic repression and selective translation of HK2 facilitates development of DLBCL.
Q38165106	Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance
Q93340499	Role of the uS9/yS16 C-terminal tail in translation initiation and elongation in Saccharomyces cerevisiae
Q36807747	Roles of helicases in translation initiation: a mechanistic view
Q26753001	Roles of the Picornaviral 3C Proteinase in the Viral Life Cycle and Host Cells
Q34480209	Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex.
Q27936034	Rpl22 is required for IME1 mRNA translation and meiotic induction in S. cerevisiae
Q100467876	SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs
Q36378135	SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex
Q43100862	SHPRH regulates rRNA transcription by recognizing the histone code in an mTOR-dependent manner
Q40606104	SINEUPs are modular antisense long non-coding RNAs that increase synthesis of target proteins in cells.
Q33990712	SRp40 and SRp55 promote the translation of unspliced human immunodeficiency virus type 1 RNA
Q37019220	STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown
Q50026430	STING-dependent translation inhibition restricts RNA virus replication.
Q38899164	Sam68 Regulates S6K1 Alternative Splicing during Adipogenesis
Q34593770	Sapovirus translation requires an interaction between VPg and the cap binding protein eIF4E.
Q47094431	Sbp1 modulates the translation of Pab1 mRNA in a poly(A)- and RGG-dependent manner
Q27934779	Scd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins.
Q36506925	Selection of suitable reference genes for qRT-PCR normalization during leaf development and hormonal stimuli in tea plant (Camellia sinensis).
Q33649143	Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae
Q38502030	Selective mRNA translation in erythropoiesis
Q42520100	Selective regulation of GluA subunit synthesis and AMPA receptor-mediated synaptic function and plasticity by the translation repressor 4E-BP2 in hippocampal pyramidal cells.
Q36228623	Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules
Q34117251	Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.
Q41935373	Sequence features of viral and human Internal Ribosome Entry Sites predictive of their activity.
Q41643142	Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation
Q92518977	Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster
Q38700659	Signaling crosstalk between the mTOR complexes
Q54118148	Signaling pathways involved in the regulation of mRNA translation.
Q26777735	Signalling to eIF4E in cancer
Q35155330	Small Regulatory RNA and Legionella pneumophila.
Q34621731	Small molecule screen reveals regulation of survival motor neuron protein abundance by Ras proteins
Q42588340	Small, synthetic, GC-rich mRNA stem-loop modules 5' proximal to the AUG start-codon predictably tune gene expression in yeast
Q39006692	Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells.
Q47146730	Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1.
Q36164805	So you want to know if your message has an IRES?
Q37715121	Spatially restricting gene expression by local translation at synapses
Q90069159	Spatio-temporal expression of ANK2 promotes cytokinesis in oocytes
Q47423991	Specialized ribosomes and specific ribosomal protein paralogs control translation of mitochondrial proteins
Q33689623	Specialized ribosomes: a new frontier in gene regulation and organismal biology
Q34825723	Specialized yeast ribosomes: a customized tool for selective mRNA translation.
Q39390082	Specific Increase of Protein Levels by Enhancing Translation Using Antisense Oligonucleotides Targeting Upstream Open Frames
Q27339698	Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity
Q26796990	Specificity and nonspecificity in RNA-protein interactions
Q39814996	Starting too soon: upstream reading frames repress downstream translation
Q35567160	Stat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugs
Q39610258	Stationary phase in Trypanosoma cruzi epimastigotes as a preadaptive stage for metacyclogenesis
Q35948849	Stoichiometry and Change of the mRNA Closed-Loop Factors as Translating Ribosomes Transit from Initiation to Elongation
Q26747461	Stress Response and Translation Control in Rotavirus Infection
Q35689148	Stress granules, P-bodies and cancer.
Q38894741	Stress puts TIA on TOP.
Q36462460	Stress-induced inhibition of translation independently of eIF2α phosphorylation
Q37524374	Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation.
Q33726348	Stress-sensitive regulation of IFRD1 mRNA decay is mediated by an upstream open reading frame
Q30497757	Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae
Q38720884	Stress-specific differences in assembly and composition of stress granules and related foci
Q27676748	Structural Analysis of the DAP5 MIF4G Domain and Its Interaction with eIF4A
Q38459563	Structural Insights into tRNA Dynamics on the Ribosome
Q27676269	Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E
Q24300025	Structural analysis and functional implications of the negative mTORC1 regulator REDD1
Q55000801	Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.
Q67199185	Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor
Q27674684	Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation
Q35213072	Structural basis for regulation of RNA-binding proteins by phosphorylation
Q35088062	Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit
Q38830343	Structural basis for the biological relevance of the invariant apical stem in IRES-mediated translation.
Q27695601	Structural basis for the inhibition of the eukaryotic ribosome
Q34164918	Structural features of the Seneca Valley virus internal ribosome entry site (IRES) element: a picornavirus with a pestivirus-like IRES
Q27681329	Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes
Q27935687	Structural integrity of {alpha}-helix H12 in translation initiation factor eIF5B is critical for 80S complex stability.
Q44179324	Structural scaffold for eIF4E binding selectivity of 4E-BP isoforms: crystal structure of eIF4E binding region of 4E-BP2 and its comparison with that of 4E-BP1.
Q42276001	Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery
Q38844599	Structure of Ty1 Internally Initiated RNA Influences Restriction Factor Expression
Q38776106	Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation
Q27684744	Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations
Q40108796	Study of RNA-A Initiation Translation of The Infectious Pancreatic Necrosis Virus
Q42229837	Sumoylation of eIF4A2 affects stress granule formation.
Q38790535	Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells.
Q35970811	Survival motor neuron affects plastin 3 protein levels leading to motor defects
Q34438777	Sustained translational repression of lactate dehydrogenase 1 in Toxoplasma gondii bradyzoites is conferred by a small regulatory RNA hairpin
Q41728227	Switching Protein Localization by Site-Directed RNA Editing under Control of Light
Q37134074	Synchronized mitochondrial and cytosolic translation programs
Q34779422	Synergistic activation of eIF4A by eIF4B and eIF4G.
Q34020246	Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing
Q37327958	Synthesis and evaluation of fluorescent cap analogues for mRNA labelling
Q36796359	Synthesis of N²-modified 7-methylguanosine 5'-monophosphates as nematode translation inhibitors
Q38995037	Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein-protein interaction
Q36070860	Synthesis of two SAPAP3 isoforms from a single mRNA is mediated via alternative translational initiation
Q38383986	Synthetic biology approaches to biological containment: pre-emptively tackling potential risks
Q42174382	Synthetic human cell fate regulation by protein-driven RNA switches
Q63979742	Synthetic mRNA capping
Q36967232	Systematic analysis of the PTEN 5' leader identifies a major AUU initiated proteoform
Q57590461	Systemic IL-6 regulation of eccentric contraction-induced muscle protein synthesis
Q36593913	Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus
Q64060900	Systems based analysis of human embryos and gene networks involved in cell lineage allocation
Q37661871	TISdb: a database for alternative translation initiation in mammalian cells
Q42688874	TITER: predicting translation initiation sites by deep learning
Q38847261	TRM6/61 connects PKCα with translational control through tRNAi(Met) stabilization: impact on tumorigenesis.
Q48244721	Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression.
Q37622949	Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer
Q38624930	Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain
Q35208375	Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
Q28535212	Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide
Q39172901	Targeting of protein translation as a new treatment paradigm for prostate cancer
Q33922370	Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition
Q98567786	Targeting stress granules: A novel therapeutic strategy for human diseases
Q36237322	Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein
Q38368049	Targeting the translation machinery in cancer
Q33747291	Targeting the translational machinery as a novel treatment strategy for hematologic malignancies
Q27027284	Targeting translation initiation in breast cancer
Q102060901	Targeting translation regulators improves cancer therapy
Q38699320	Targeting translation: eIF4E as an emerging anticancer drug target
Q92035451	Targetome analysis of chaperone-mediated autophagy in cancer cells
Q57054052	Technique Development for Probing RNA Structure In Vivo and Genome-Wide
Q33614328	Temperature protects insect cells from infection by cricket paralysis virus
Q90640189	Testing Proximity of Genomic Regions to Transcription Start Sites and Enhancers Complements Gene Set Enrichment Testing
Q40721662	Tethered Function Assays as Tools to Elucidate the Molecular Roles of RNA-Binding Proteins
Q47830255	Tetracaine, a local anesthetic, preferentially induces translational inhibition with processing body formation rather than phosphorylation of eIF2α in yeast.
Q34261428	The 3' untranslated region of Pea Enation Mosaic Virus contains two T-shaped, ribosome-binding, cap-independent translation enhancers
Q42428083	The 3' untranslated region of the Andes hantavirus small mRNA functionally replaces the poly(A) tail and stimulates cap-dependent translation initiation from the viral mRNA.
Q35631534	The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation
Q37046035	The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes
Q41510614	The 5' UTR of HIV-1 full-length mRNA and the Tat viral protein modulate the programmed -1 ribosomal frameshift that generates HIV-1 enzymes
Q58740074	The 5' Untranslated Region of Human Bocavirus Capsid Transcripts Regulates Viral mRNA Biogenesis and Alternative Translation
Q33887817	The 5' untranslated region of the human T-cell lymphotropic virus type 1 mRNA enables cap-independent translation initiation
Q34155548	The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway.
Q33608842	The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation
Q38606851	The Ambystoma tigrinum virus (ATV) RNase III gene can modulate host PKR activation and interferon production
Q37582298	The Arc of synaptic memory
Q44017806	The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo
Q36776327	The Bin3 RNA methyltransferase targets 7SK RNA to control transcription and translation
Q35660035	The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation
Q42324171	The DDX6-4E-T interaction mediates translational repression and P-body assembly
Q36963199	The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA
Q24305010	The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes
Q35917446	The DHX33 RNA Helicase Promotes mRNA Translation Initiation
Q28728044	The Distribution of eIF4E-Family Members across Insecta
Q28116373	The EIF4G1 gene and Parkinson's disease
Q28397675	The Effect of Growth Hormone Administration on the Regulation of Mitochondrial Apoptosis in-Vivo
Q42989827	The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites
Q37112104	The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy.
Q39342221	The Growing Toolbox for Protein Synthesis Studies.
Q28535448	The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA
Q42957645	The Hsp90 inhibitor geldanamycin abrogates colocalization of eIF4E and eIF4E-transporter into stress granules and association of eIF4E with eIF4G.
Q54265402	The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells.
Q47985263	The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives.
Q61307023	The Leishmania PABP1–eIF4E4 interface: a novel 5′–3′ interaction architecture for trans-spliced mRNAs
Q47278597	The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain
Q48060988	The Molecular Mechanism of Glucagon-Like Peptide-1 Therapy in Alzheimer's Disease, Based on a Mechanistic Target of Rapamycin Pathway.
Q64924595	The Protozoan Parasite Toxoplasma gondii Selectively Reprograms the Host Cell Translatome.
Q33700385	The QKI-6 RNA Binding Protein Localizes with the MBP mRNAs in Stress Granules of Glial Cells
Q24308702	The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration
Q50117575	The Regulation of Translation in Alphavirus-Infected Cells.
Q46774762	The Role of Cytoplasmic mRNA Cap-Binding Protein Complexes in Trypanosoma brucei and Other Trypanosomatids.
Q88650023	The Role of RNA in Biological Phase Separations
Q35826346	The Role of Structural Elements of the 5'-Terminal Region of p53 mRNA in Translation under Stress Conditions Assayed by the Antisense Oligonucleotide Approach
Q59812449	The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders
Q28538729	The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2
Q107455687	The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation
Q27939958	The SESA network links duplication of the yeast centrosome with the protein translation machinery
Q50074822	The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression
Q92854518	The Tumor Suppressor Roles of MYBBP1A, a Major Contributor to Metabolism Plasticity and Stemness
Q47107470	The Unexpected Tuners: Are LncRNAs Regulating Host Translation during Infections?
Q34559697	The activity of the HIV-1 IRES is stimulated by oxidative stress and controlled by a negative regulatory element
Q27014321	The balance of protein expression and degradation: an ESCRTs point of view
Q28822098	The complete chemical structure of Saccharomyces cerevisiae rRNA: partial pseudouridylation of U2345 in 25S rRNA by snoRNA snR9
Q34882908	The conserved histone deacetylase Rpd3 and its DNA binding subunit Ume6 control dynamic transcript architecture during mitotic growth and meiotic development.
Q28116053	The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA
Q35551757	The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.
Q90113788	The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4
Q39606799	The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress
Q47215309	The eIF4E2-Directed Hypoxic Cap-Dependent Translation Machinery Reveals Novel Therapeutic Potential for Cancer Treatment
Q35960491	The eIF4F and eIFiso4F Complexes of Plants: An Evolutionary Perspective
Q34116590	The efficiency of selenocysteine incorporation is regulated by translation initiation factors
Q38221025	The emergence of proteome-wide technologies: systematic analysis of proteins comes of age.
Q36106977	The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase
Q34318188	The evolution of the TOR pathway and its role in cancer
Q39051259	The exon junction complex: a lifelong guardian of mRNA fate
Q27027797	The expanding role of mTOR in cancer cell growth and proliferation
Q37477468	The fate of the messenger is pre-determined: a new model for regulation of gene expression
Q37573886	The frontal cortex IGF system is down regulated in the term, intrauterine growth restricted fetal baboon.
Q33564231	The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis
Q42714131	The influence of physical exercise on the generation of TGF-β1, PDGF-AA, and VEGF-A in adipose tissue
Q41627594	The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma
Q37019305	The insulin receptor cellular IRES confers resistance to eIF4A inhibition
Q52612469	The integrated stress response regulates BMP signalling through effects on translation.
Q37565821	The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes
Q37254375	The kissing-loop T-shaped structure translational enhancer of Pea enation mosaic virus can bind simultaneously to ribosomes and a 5' proximal hairpin
Q35242019	The long non-coding RNA GAS5 cooperates with the eukaryotic translation initiation factor 4E to regulate c-Myc translation
Q41816418	The mRNA of human cytoplasmic arginyl-tRNA synthetase recruits prokaryotic ribosomes independently
Q35478977	The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability
Q37409754	The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells.
Q34278940	The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.
Q29547270	The mechanism of eukaryotic translation initiation and principles of its regulation
Q38904795	The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma.
Q36906415	The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication
Q26798135	The molecular mechanism of translational control via the communication between the microRNA pathway and RNA-binding proteins
Q39754200	The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases.
Q56797665	The natural compound silvestrol inhibits hepatitis E virus (HEV) replication in vitro and in vivo
Q33769223	The nematode eukaryotic translation initiation factor 4E/G complex works with a trans-spliced leader stem-loop to enable efficient translation of trimethylguanosine-capped RNAs
Q34980907	The new face of the old molecules: crustin Pm4 and transglutaminase type I serving as rnps down-regulate astakine-mediated hematopoiesis
Q34776644	The novel gene twenty-four defines a critical translational step in the Drosophila clock.
Q34426626	The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation
Q50200832	The p90 ribosomal S6 kinase-UBR5 pathway controls Toll-like receptor signaling via miRNA-induced translational inhibition of tumor necrosis factor receptor-associated factor 3.
Q36332325	The pharmacology of nociceptor priming
Q34130177	The pioneer round of translation: features and functions
Q34003878	The plausible reason why the length of 5' untranslated region is unrelated to organismal complexity
Q38255027	The proteome under translational control
Q50703682	The return of the nucleus: transcriptional and epigenetic control of autophagy.
Q36844633	The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs
Q38838979	The ribosome in action: Tuning of translational efficiency and protein folding
Q24634193	The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments
Q52315005	The ribosome, (slow) beating heart of cancer (stem) cell.
Q92972101	The role of CSDE1 in translational reprogramming and human diseases
Q37954130	The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β-cell mass: implications in the development of type-2 diabetes.
Q33800179	The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation
Q38026037	The role of protein phosphorylation in the gustatory cortex and amygdala during taste learning
Q41867949	The role of translation initiation regulation in haematopoiesis
Q94527307	The roles and mechanisms of YTH domain-containing proteins in cancer development and progression
Q28834524	The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha
Q39816699	The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing
Q60046032	The split protein phosphatase system
Q27022315	The structure and function of the eukaryotic ribosome
Q27675638	The structure of the eukaryotic ribosome at 3.0 Å resolution
Q35546455	The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206
Q30591171	The translation initiation factor eIF3i up-regulates vascular endothelial growth factor A, accelerates cell proliferation, and promotes angiogenesis in embryonic development and tumorigenesis
Q57176977	The translational landscape of Arabidopsis mitochondria
Q42215323	The translational repressor 4E-BP called to order by eIF4E: new structural insights by SAXS.
Q102063589	The translational repressor 4E-BP1 regulates RRM2 levels and functions as a tumor suppressor in Ewing sarcoma tumors
Q34212218	The tumor suppressive role of eIF3f and its function in translation inhibition and rRNA degradation
Q37274496	The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes
Q36473355	Therapeutic interventions to disrupt the protein synthetic machinery in melanoma
Q60680291	Therapeutic opportunities for pain medicines via targeting of specific translation signaling mechanisms
Q90288861	Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells
Q30624184	Three distinct ribosome assemblies modulated by translation are the building blocks of polysomes
Q34211540	Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity
Q38361655	Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state
Q35319555	To be or not to be: the regulation of mRNA fate as a survival strategy during mammalian hibernation
Q36629755	Toward a genome-wide landscape of translational control
Q36906420	Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss
Q31168602	Toxic-selenium and low-selenium transcriptomes in Caenorhabditis elegans: toxic selenium up-regulates oxidoreductase and down-regulates cuticle-associated genes
Q24297096	Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E
Q89661626	Trait differentiation and modular toxin expression in palm-pitvipers
Q33555634	Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.
Q94564366	Transcription and Translation Inhibitors in Cancer Treatment
Q91672709	Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition
Q36052441	Transcriptional repression of ATF4 gene by CCAAT/enhancer-binding protein β (C/EBPβ) differentially regulates integrated stress response
Q37672409	Transcriptome Analysis of Flowering Time Genes under Drought Stress in Maize Leaves
Q24630900	Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
Q38187430	Transcriptome-wide studies uncover the diversity of modes of mRNA recruitment to eukaryotic ribosomes.
Q53659772	Transfer RNA fragmentation and protein translation dynamics in the course of kidney injury.
Q34989523	Transimulation - protein biosynthesis web service
Q37698109	Translate to divide: control of the cell cycle by protein synthesis
Q90269368	Translating Translation to Mechanisms of Cardiac Hypertrophy
Q64244241	Translating the Hypoxic Response-the Role of HIF Protein Translation in the Cellular Response to Low Oxygen
Q26747114	Translating the epitranscriptome
Q58374805	Translation acrobatics: how cancer cells exploit alternate modes of translational initiation
Q52593667	Translation and Translational Control in Dinoflagellates.
Q37343526	Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells
Q47374105	Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs
Q37024596	Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3.
Q33814325	Translation control: a multifaceted regulator of inflammatory response
Q34525975	Translation directed by hepatitis A virus IRES in the absence of active eIF4F complex and eIF2
Q27330024	Translation dynamics of single mRNAs in live cells and neurons
Q46286420	Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames
Q38104237	Translation factors and ribosomal proteins control tumor onset and progression: how?
Q34549017	Translation from unconventional 5' start sites drives tumour initiation
Q92580474	Translation imaging of single mRNAs in established cell lines and primary cultured neurons
Q42240387	Translation initiation complex formation in the crenarchaeon Sulfolobus solfataricus
Q38776953	Translation initiation events on structured eukaryotic mRNAs generate gene expression noise.
Q30416020	Translation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonization
Q39383867	Translation initiation factor eIF4E is a target for tumor cell radiosensitization.
Q37993753	Translation initiation in colorectal cancer
Q38053243	Translation initiation is driven by different mechanisms on the HIV-1 and HIV-2 genomic RNAs.
Q38700670	Translation initiation of the HIV-1 mRNA.
Q37741908	Translation initiation of viral mRNAs
Q28298359	Translation initiation: variations in the mechanism can be anticipated
Q28247679	Translation initiator EIF4G1 mutations in familial Parkinson disease
Q40120228	Translation is actively regulated during the differentiation of CD8+ effector T cells.
Q28771734	Translation of 5' leaders is pervasive in genes resistant to eIF2 repression
Q33551532	Translation of CircRNAs
Q37604170	Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.
Q37421101	Translation of the FMR1 mRNA is not influenced by AGG interruptions
Q38782096	Translation of the human erythropoietin transcript is regulated by an upstream open reading frame in response to hypoxia
Q64271044	Translation of upstream open reading frames in a model of neuronal differentiation
Q28479039	Translation of viral mRNA without active eIF2: the case of picornaviruses
Q42282738	Translation of viral mRNAs that do not require eIF4E is blocked by the inhibitor 4EGI-1.
Q90629458	Translation regulation in skin cancer from a tRNA point of view
Q92587789	Translation regulation in the spinal dorsal horn - A key mechanism for development of chronic pain
Q34049312	Translation without eIF2 promoted by poliovirus 2A protease
Q35224421	Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1.
Q47220043	Translational Control Mechanisms in Persistent Pain
Q61448087	Translational Control in Stem Cells
Q90365771	Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
Q41123932	Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development
Q89882462	Translational Inhibition of α-Neurexin 2
Q92162430	Translational Regulation by Upstream Open Reading Frames and Human Diseases
Q37802038	Translational Regulation of Gene Expression during Conditions of Cell Stress
Q89944336	Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers
Q41813629	Translational control and autism-like behaviors
Q27002504	Translational control by 3'-UTR-binding proteins
Q38016101	Translational control by changes in poly(A) tail length: recycling mRNAs.
Q36673748	Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine
Q26865758	Translational control by heme-regulated eIF2α kinase during erythropoiesis
Q37178443	Translational control by negative-strand RNA viruses: methods for the study of a crucial virus/host interaction
Q33556172	Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
Q36555212	Translational control in cancer etiology
Q37717999	Translational control in cancer.
Q38008495	Translational control in cellular and developmental processes
Q34332753	Translational control in germline stem cell development
Q36487154	Translational control in synaptic plasticity and cognitive dysfunction
Q49790269	Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils
Q48089888	Translational control of ERK signaling through miRNA/4EHP-directed silencing
Q30365036	Translational control of auditory imprinting and structural plasticity by eIF2α.
Q37987280	Translational control of cell fate: from integration of environmental signals to breaching anticancer defense.
Q44915601	Translational control of cell growth and malignancy by the CPEBs
Q37377856	Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling
Q38212816	Translational control of immune responses: from transcripts to translatomes
Q36932559	Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells
Q35121843	Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α.
Q42348648	Translational control of mRNAs by 3'-Untranslated region binding proteins.
Q28551851	Translational control of nociception via 4E-binding protein 1
Q34458034	Translational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cells
Q38715693	Translational control of the fibroblast-extracellular matrix association: An application to pulmonary fibrosis
Q34302212	Translational control through eIF2alpha phosphorylation during the Leishmania differentiation process
Q35393305	Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR.
Q35056643	Translational profiling in childhood acute lymphoblastic leukemia: no evidence for glucocorticoid regulation of mRNA translation.
Q52660636	Translational profiling of B cells infected with the Epstein-Barr virus reveals 5' leader ribosome recruitment through upstream open reading frames.
Q35513475	Translational regulation during stage transitions in malaria parasites
Q35579583	Translational regulation in nutrigenomics
Q89115530	Translational regulation is a key determinant of the cellular response to benzo[a]pyrene
Q38194482	Translational regulator eIF2α in tumor
Q40041919	Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region
Q37710220	Translational reprogramming in cellular stress response
Q38266157	Translatome profiling: methods for genome-scale analysis of mRNA translation
Q46268150	TranslatomeDB: a comprehensive database and cloud-based analysis platform for translatome sequencing data
Q99711224	Treatment With Medicinal Mushroom Extract Mixture Inhibits Translation and Reprograms Metabolism in Advanced Colorectal Cancer Animal Model as Evidenced by Tandem Mass Tags Proteomics Analysis
Q36215289	Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway
Q37119721	Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action
Q94586244	Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice
Q37256287	Tumor cell survival dependence on the DHX9 DExH-box helicase
Q41392040	Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer
Q39759975	Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathway
Q36918294	Tumor suppressor p16(INK4a) inhibits cancer cell growth by downregulating eEF1A2 through a direct interaction.
Q39708546	Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA.
Q36545047	Twist1-mediated 4E-BP1 regulation through mTOR in non-small cell lung cancer
Q37467356	Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome
Q47147251	Two distinct nodes of translational inhibition in the Integrated Stress Response.
Q51553333	UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression.
Q47307244	USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1.
Q39517341	UVA, UVB and UVC induce differential response signaling pathways converged on the eIF2α phosphorylation
Q37309705	Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression
Q90019272	Unconventional Estrogen Signaling in Health and Disease
Q51825443	Uncovering the PKR pathway's potential for treatment of tumors.
Q38535203	Unique translation initiation of mRNAs-containing TISU element
Q39147692	Untranslated regions of mRNA and their role in regulation of gene expression in protozoan parasites.
Q57060633	Unusual dicistronic expression from closely spaced initiation codons in an umbravirus subgenomic RNA
Q39733957	Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1.
Q34384024	Upregulation of eIF5B controls cell-cycle arrest and specific developmental stages
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Q34603238	Upstream open reading frame in 5'-untranslated region reduces titin mRNA translational efficiency
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Q36432681	dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection
Q41510514	eIF1 modulates the recognition of suboptimal translation initiation sites and steers gene expression via uORFs
Q37228876	eIF1A/eIF5B interaction network and its functions in translation initiation complex assembly and remodeling
Q28833240	eIF2 interactions with initiator tRNA and eIF2B are regulated by post-translational modifications and conformational dynamics
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Q27933768	eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core
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Q37369248	eIF2α phosphorylation controls thermal nociception
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Q52445969	eIF3: a factor for human health and disease.
Q64889448	eIF3a mediates HIF1α-dependent glycolytic metabolism in hepatocellular carcinoma cells through translational regulation.
Q37261782	eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary
Q28749125	eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease
Q91272163	eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
Q35167618	eIF4A1 is a promising new therapeutic target in ER-negative breast cancer
Q64087037	eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS
Q36962884	eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants.
Q50326398	eIF4E Phosphorylation Influences Bdnf mRNA Translation in Mouse Dorsal Root Ganglion Neurons
Q53687330	eIF4E Phosphorylation in Prostate Cancer.
Q35160012	eIF4E as a control target for viruses
Q35096727	eIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells.
Q59136306	eIF4E-Dependent Translational Control: A Central Mechanism for Regulation of Pain Plasticity
Q38496498	eIF4E-binding protein regulation of mRNAs with differential 5'-UTR secondary structure: a polyelectrostatic model for a component of protein-mRNA interactions
Q51440892	eIF4G-an integrator of mRNA metabolism?
Q27931061	eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
Q100305048	eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer
Q37641772	eIF5B increases ASAP1 expression to promote HCC proliferation and invasion
Q28586333	eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription
Q92606664	eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons
Q64227724	hCLE/RTRAF-HSPC117-DDX1-FAM98B: A New Cap-Binding Complex That Activates mRNA Translation
Q36749030	ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans
Q47436391	m6A Facilitates eIF4F-Independent mRNA Translation
Q42115889	mRNA 3' tagging is induced by nonsense-mediated decay and promotes ribosome dissociation.
Q36506791	mRNA decay during herpes simplex virus (HSV) infections: mutations that affect translation of an mRNA influence the sites at which it is cleaved by the HSV virion host shutoff (Vhs) protein
Q37907202	mRNA export and cancer
Q37856199	mRNA helicases: the tacticians of translational control
Q41032742	mRNA modifications: Dynamic regulators of gene expression?
Q58600311	mRNAs and lncRNAs intrinsically form secondary structures with short end-to-end distances
Q36189835	mRNP granules. Assembly, function, and connections with disease
Q27007511	mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions
Q35878519	mTOR complex 2 signaling and functions
Q38156016	mTOR complexes in neurodevelopmental and neuropsychiatric disorders
Q36156993	mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.
Q41716371	mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation
Q27851707	mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors
Q47141803	mTOR-sensitive translation: Cleared fog reveals more trees
Q50142087	mTORC1 Balances Cellular Amino Acid Supply with Demand for Protein Synthesis through Post-transcriptional Control of ATF4.
Q97529121	mTORC1 Enhances Early Phase Ribosome Processivity
Q42321289	mTORC1 and -2 Coordinate Transcriptional and Translational Reprogramming in Resistance to DNA Damage and Replicative Stress in Breast Cancer Cells.
Q36768697	mTORC1 and CK2 coordinate ternary and eIF4F complex assembly
Q27012468	mTORC1 signaling activates NRF1 to increase cellular proteasome levels
Q39243905	mTORC1 signaling and the metabolic control of cell growth
Q47986450	mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.
Q37395961	mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors.
Q58764425	mTORC1/2 inhibition re-sensitizes platinum-resistant ovarian cancer by disrupting selective translation of DNA damage and survival mRNAs
Q24305343	mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
Q38845695	miR-34c-3p functions as a tumour suppressor by inhibiting eIF4E expression in non-small cell lung cancer
Q34299534	microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion
Q41215687	nRC: non-coding RNA Classifier based on structural features.
Q35960087	nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
Q38985225	p53-directed translational control can shape and expand the universe of p53 target genes.
Q24306090	p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity
Q39204379	p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability
Q42638077	uORF, a regulatory mechanism of the Arabidopsis polyamine oxidase 2.
Q27012671	βA3/A1-crystallin: more than a lens protein

review article	Q7318358
scholarly article	Q13442814

P356	DOI	10.1016/J.CELL.2009.01.042
P3181	OpenCitations bibliographic resource ID	566739
P932	PMC publication ID	3610329
P698	PubMed publication ID	19239892
P5875	ResearchGate publication ID	24037492

P50	author	Nahum Sonenberg	Q904654
P2093	author name string	Alan G Hinnebusch
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P433	issue	4
P407	language of work or name	English	Q1860
P304	page(s)	731-45
P577	publication date	2009-02-20
P1433	published in	Cell	Q655814
P1476	title	Regulation of translation initiation in eukaryotes: mechanisms and biological targets
P478	volume	136

Q107603118	Eukaryotic translation initiation factor 4F, EIF4A1 and EIF4G1 variant
Q107603121	Eukaryotic translation initiation factor 4F, EIF4A1 and EIF4G3 variant
Q107603116	Eukaryotic translation initiation factor 4F, EIF4A2 and EIF4G1 variant
Q107603120	Eukaryotic translation initiation factor 4F, EIF4A2 and EIF4G3 variant

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

scientific article (publication date: 20 February 2009)

Reverse relations