| scholarly article | Q13442814 |
| P50 | author | Nehal Thakor | Q89914840 |
| P2093 | author name string | Divya Khandige Sharma | |
| Harshil Patel | |||
| Nirujah Balasingam | |||
| Kamiko Bressler | |||
| P2860 | cites work | Mutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the beta subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivo | Q22254065 |
| Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation | Q24290282 | ||
| Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product | Q24291248 | ||
| An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells | Q24293077 | ||
| The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins | Q24293745 | ||
| The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro | Q24302384 | ||
| Assembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decay | Q24310190 | ||
| Human DDX3 functions in translation and interacts with the translation initiation factor eIF3 | Q24313521 | ||
| Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors | Q24317336 | ||
| Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase | Q24317685 | ||
| Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation | Q24336547 | ||
| A directed protein interaction network for investigating intracellular signal transduction | Q24337382 | ||
| CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression | Q24535320 | ||
| mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin | Q24543920 | ||
| Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translation | Q24554132 | ||
| Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms | Q24558492 | ||
| Mechanisms of translational regulation by a human eIF5-mimic protein | Q24634138 | ||
| Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions | Q24657441 | ||
| Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans | Q24658225 | ||
| Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells | Q24805438 | ||
| Could the eIF2α-Independent Translation Be the Achilles Heel of Cancer? | Q26774488 | ||
| The translational factor eIF3f: the ambivalent eIF3 subunit | Q27016102 | ||
| eIF2-dependent and eIF2-independent modes of initiation on the CSFV IRES: a common role of domain II | Q27485879 | ||
| PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains | Q27649928 | ||
| Gene expression regulation by upstream open reading frames and human disease | Q27693182 | ||
| The joining of ribosomal subunits in eukaryotes requires eIF5B. | Q27876221 | ||
| Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation | Q27940095 | ||
| Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells | Q27940265 | ||
| Regulation of translation initiation in eukaryotes: mechanisms and biological targets | Q28111696 | ||
| eIF3 targets cell-proliferation messenger RNAs for translational activation or repression | Q28115960 | ||
| The mechanism of translation initiation on Type 1 picornavirus IRESs | Q28116162 | ||
| Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome | Q28117731 | ||
| La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1) | Q28118644 | ||
| eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation | Q28118876 | ||
| The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr | Q28187615 | ||
| Global quantification of mammalian gene expression control | Q28238103 | ||
| Initiation factor eIF3 and regulation of mRNA translation, cell growth, and cancer | Q28250946 | ||
| mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events | Q28281590 | ||
| Schwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor subunit c (eIF3c) | Q28298948 | ||
| The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation | Q28504536 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide | Q28535212 | ||
| Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway | Q28580284 | ||
| Interaction with eIF5B is essential for Vasa function during development. | Q50797471 | ||
| Characterization of translation initiation factor 5 (eIF5) from Saccharomyces cerevisiae. Functional homology with mammalian eIF5 and the effect of depletion of eIF5 on protein synthesis in vivo and in vitro. | Q52193428 | ||
| Cell cycle and activation of CK2. | Q53464398 | ||
| Effect of a natural mutation in the 5' untranslated region on the translational control of p53 mRNA. | Q54480499 | ||
| Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach | Q61872982 | ||
| Levels, phosphorylation status and cellular localization of translational factor eIF2 in gastrointestinal carcinomas | Q73859285 | ||
| Nuclear localization of protein kinase CK2 catalytic subunit (CK2alpha) is associated with poor prognostic factors in human prostate cancer | Q79699288 | ||
| DAP5 and IRES-mediated translation during programmed cell death | Q81628766 | ||
| Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein | Q36237322 | ||
| Translation initiation: structures, mechanisms and evolution | Q36272181 | ||
| Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway | Q36313774 | ||
| Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response | Q36322641 | ||
| The PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells | Q36426519 | ||
| RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation. | Q36445265 | ||
| Physical evidence supporting a ribosomal shunting mechanism of translation initiation for BACE1 mRNA | Q36477544 | ||
| Translational control in cancer etiology | Q36555212 | ||
| Nucleotide composition of cellular internal ribosome entry sites defines dependence on NF45 and predicts a posttranscriptional mitotic regulon | Q36559689 | ||
| Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability. | Q36618993 | ||
| Phosphorylated 4EBP1 is associated with tumor progression and poor prognosis in Xp11.2 translocation renal cell carcinoma | Q36741509 | ||
| Mechanisms of action of Bcl-2 family proteins | Q36932838 | ||
| Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation | Q36949719 | ||
| Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish | Q36960187 | ||
| Cap-independent regulation of gene expression in apoptosis | Q37000364 | ||
| Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity | Q37104055 | ||
| Canonical initiation factor requirements of the Myc family of internal ribosome entry segments | Q37110582 | ||
| Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3. | Q37162273 | ||
| Eukaryotic initiation factors (eIF) 2alpha and 4E expression, localization, and phosphorylation in brain tumors | Q37174030 | ||
| Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation | Q37336923 | ||
| Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs | Q37379400 | ||
| Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells | Q37621199 | ||
| Role of translation initiation factor 4G in lifespan regulation and age-related health | Q37663839 | ||
| Translational control in cancer. | Q37717999 | ||
| Stress management at the ER: regulators of ER stress-induced apoptosis | Q37990288 | ||
| Translational control in cellular and developmental processes | Q38008495 | ||
| Targeting the ATF4 pathway in cancer therapy | Q38046235 | ||
| Eukaryotic translation initiation factors in cancer development and progression | Q38119725 | ||
| IRES mediated translational regulation of p53 isoforms | Q38171767 | ||
| Translational regulator eIF2α in tumor | Q38194482 | ||
| Stress-mediated translational control in cancer cells | Q38281204 | ||
| Regulation of Eukaryotic Initiation Factor 4E (eIF4E) Phosphorylation by Mitogen-Activated Protein Kinase Occurs through Modulation of Mnk1-eIF4G Interaction | Q38341049 | ||
| Int6/eIF3e is essential for proliferation and survival of human glioblastoma cells. | Q38344755 | ||
| Targeting the translation machinery in cancer | Q38368049 | ||
| Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells | Q34706800 | ||
| Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion | Q34754654 | ||
| Heterogeneous nuclear ribonucleoprotein C modulates translation of c-myc mRNA in a cell cycle phase-dependent manner | Q34811629 | ||
| Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of EIF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma. | Q34894379 | ||
| Determinants of translation efficiency and accuracy | Q35006962 | ||
| The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment | Q35032545 | ||
| An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation | Q35065850 | ||
| RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer | Q35216351 | ||
| DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation | Q35476384 | ||
| Starting the protein synthesis machine: eukaryotic translation initiation. | Q35591866 | ||
| IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress. | Q35672175 | ||
| Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response | Q35677479 | ||
| Subcellular relocalization of a trans-acting factor regulates XIAP IRES-dependent translation. | Q35723781 | ||
| eIF4E--from translation to transformation | Q35750110 | ||
| Eukaryotic Translation Initiation Factor 4E Is a Feed-Forward Translational Coactivator of Transforming Growth Factor β Early Protransforming Events in Breast Epithelial Cells. | Q35914014 | ||
| Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2. | Q35943987 | ||
| OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. | Q35964463 | ||
| Internal ribosome entry sites in cellular mRNAs: mystery of their existence. | Q36062950 | ||
| Internal ribosome entry segment-mediated translation during apoptosis: the role of IRES-trans-acting factors | Q36131048 | ||
| The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation | Q28589397 | ||
| Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis | Q28593886 | ||
| The role of PKR/eIF2α signaling pathway in prognosis of non-small cell lung cancer | Q28742943 | ||
| Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression | Q29147399 | ||
| The mechanism of eukaryotic translation initiation and principles of its regulation | Q29547270 | ||
| Molecular mechanisms of translational control | Q29614568 | ||
| Translational control in stress and apoptosis | Q29615497 | ||
| The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice | Q30435990 | ||
| Loss of the eukaryotic initiation factor 3f in pancreatic cancer | Q33301656 | ||
| eIF4E expression in tumors: its possible role in progression of malignancies | Q33601639 | ||
| Biochemical quantitation of the eIF5A hypusination in Arabidopsis thaliana uncovers ABA-dependent regulation | Q33658033 | ||
| Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels. | Q33714013 | ||
| Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia | Q33772948 | ||
| c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis. | Q33961819 | ||
| The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection | Q33962536 | ||
| An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation | Q34002645 | ||
| Structural and functional diversity of viral IRESes | Q34018630 | ||
| Translation of TRAF1 is regulated by IRES-dependent mechanism and stimulated by vincristine | Q34020258 | ||
| eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression | Q34069836 | ||
| Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations | Q34200605 | ||
| Regulation of interferon pathway in 2-methoxyestradiol-treated osteosarcoma cells | Q34202110 | ||
| The tumor suppressive role of eIF3f and its function in translation inhibition and rRNA degradation | Q34212218 | ||
| Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells. | Q34294150 | ||
| HuR controls mitochondrial morphology through the regulation of BclxL translation. | Q34349781 | ||
| Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation | Q34375074 | ||
| Upregulation of eIF5B controls cell-cycle arrest and specific developmental stages | Q34384024 | ||
| The role of eIF1 in translation initiation codon selection in Caenorhabditis elegans | Q34386878 | ||
| The role of eIF3 and its individual subunits in cancer | Q34450907 | ||
| Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry | Q34459802 | ||
| The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2. | Q34462937 | ||
| A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer | Q34518559 | ||
| Interaction of the RNP1 motif in PRT1 with HCR1 promotes 40S binding of eukaryotic initiation factor 3 in yeast | Q34563179 | ||
| Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states. | Q34624747 | ||
| Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor β1-3 (TGF-β1-3). | Q34634172 | ||
| eIF3j is located in the decoding center of the human 40S ribosomal subunit | Q34641203 | ||
| Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis | Q38428730 | ||
| CK2α phosphorylates DBC1 and is involved in the progression of gastric carcinoma and predicts poor survival of gastric carcinoma patients | Q38437053 | ||
| Role of hypoxia and vascular endothelial growth factors in lymphangiogenesis. | Q38866652 | ||
| Knockdown of eIF3d inhibits cell proliferation through G2/M phase arrest in non-small cell lung cancer | Q38871165 | ||
| Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis | Q38917874 | ||
| hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling. | Q38946989 | ||
| The integrated stress response. | Q38954583 | ||
| The ERK/eIF4F/Bcl-XL pathway mediates SGP-2 induced osteosarcoma cells apoptosis in vitro and in vivo | Q38975221 | ||
| LMP1 stimulates the transcription of eIF4E to promote the proliferation, migration and invasion of human nasopharyngeal carcinoma | Q38996496 | ||
| Effect of siRNA-mediated knockdown of eIF3c gene on survival of colon cancer cells | Q39144259 | ||
| Decreased eIF3e/Int6 expression causes epithelial-to-mesenchymal transition in breast epithelial cells | Q39294219 | ||
| Effect of mutations on the p53 IRES RNA structure: implications for de-regulation of the synthesis of p53 isoforms. | Q39593054 | ||
| Int6 regulates both proteasomal degradation and translation initiation and is critical for proper formation of acini by human mammary epithelium | Q39648518 | ||
| Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1. | Q39733957 | ||
| Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. | Q39761567 | ||
| Identification of cellular factors binding to acetylated HIV-1 integrase. | Q39762216 | ||
| Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases | Q39969349 | ||
| DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis | Q39986438 | ||
| Interaction of heterogeneous nuclear ribonucleoprotein C1/C2 with a novel cis-regulatory element within p53 mRNA as a response to cytostatic drug treatment | Q40009471 | ||
| Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation. | Q40039212 | ||
| Individual overexpression of five subunits of human translation initiation factor eIF3 promotes malignant transformation of immortal fibroblast cells | Q40196128 | ||
| Unr, a cytoplasmic RNA-binding protein with cold-shock domains, is involved in control of apoptosis in ES and HuH7 cells | Q40211693 | ||
| The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation | Q40240022 | ||
| Inhibition of eukaryotic translation initiation factor 5A (eIF5A) hypusination impairs melanoma growth | Q40253790 | ||
| Externalization and recognition by macrophages of large subunit of eukaryotic translation initiation factor 3 in apoptotic cells | Q40404891 | ||
| Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growth | Q40565127 | ||
| Ornithine decarboxylase: an indicator for growth of NIH 3T3 fibroblasts and their c-Ha-ras transformants | Q41334285 | ||
| MD11-mediated delivery of recombinant eIF3f induces melanoma and colorectal carcinoma cell death | Q41371446 | ||
| A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism | Q41698817 | ||
| Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas | Q41822752 | ||
| The BCL-2 5′ Untranslated Region Contains an RNA G-Quadruplex-Forming Motif That Modulates Protein Expression | Q42008941 | ||
| Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2 | Q42094437 | ||
| Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression | Q42136215 | ||
| Problem-solving test: the mechanism of poliovirus-induced block of host protein synthesis in human cells | Q42233512 | ||
| An evolutionarily conserved interaction of tumor suppressor protein Pdcd4 with the poly(A)-binding protein contributes to translation suppression by Pdcd4. | Q42286555 | ||
| Implications of the Use of Eukaryotic Translation Initiation Factor 5A (eIF5A) for Prognosis and Treatment of Hepatocellular Carcinoma | Q42639936 | ||
| Phosphorylation of eIF4E attenuates its interaction with mRNA 5' cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein | Q43166736 | ||
| Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway | Q43240324 | ||
| Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial-mesenchymaltransition. | Q43931495 | ||
| Internal ribosome entry site-mediated translational regulation of ATF4 splice variant in mammalian unfolded protein response | Q44251998 | ||
| Ribosome profiling: new views of translation, from single codons to genome scale | Q44759418 | ||
| Elevated snoRNA biogenesis is essential in breast cancer | Q45093679 | ||
| An oncogenic role of eIF3e/INT6 in human breast cancer | Q45384502 | ||
| The eIF2alpha kinases inhibit vesicular stomatitis virus replication independently of eIF2alpha phosphorylation | Q45392345 | ||
| Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription. | Q47801872 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 8235121 | |
| P577 | publication date | 2016-12-19 | |
| P1433 | published in | Journal of Nucleic Acids | Q26853953 |
| P1476 | title | Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer Progression | |
| P478 | volume | 2016 |
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