| scholarly article | Q13442814 |
| P50 | author | Justin Kale | Q47155592 |
| David William Andrews | Q37838821 | ||
| P2093 | author name string | Brian Leber | |
| Aisha Shamas-Din | |||
| P2860 | cites work | Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist | Q40088689 |
| Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex | Q40237169 | ||
| Bcl-2 changes conformation to inhibit Bax oligomerization | Q40287064 | ||
| A role for proapoptotic BID in the DNA-damage response | Q40381562 | ||
| The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA. | Q40485961 | ||
| During apoptosis bcl-2 changes membrane topology at both the endoplasmic reticulum and mitochondria | Q40554731 | ||
| The super anti-apoptotic factor Bcl-xFNK constructed by disturbing intramolecular polar interactions in rat Bcl-xL. | Q40749844 | ||
| Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms | Q40976477 | ||
| Cytosolic factor- and TOM-independent import of C-tail-anchored mitochondrial outer membrane proteins | Q41092707 | ||
| Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence. | Q41509622 | ||
| Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis | Q41822569 | ||
| BH3-triggered structural reorganization drives the activation of proapoptotic BAX. | Q41884328 | ||
| Reconstitution of proapoptotic BAK function in liposomes reveals a dual role for mitochondrial lipids in the BAK-driven membrane permeabilization process | Q41975085 | ||
| Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers | Q42156839 | ||
| Reversible membrane interaction of BAD requires two C-terminal lipid binding domains in conjunction with 14-3-3 protein binding | Q42803499 | ||
| Molecular details of Bax activation, oligomerization, and membrane insertion. | Q42910802 | ||
| Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices | Q43235008 | ||
| Membrane promotes tBID interaction with BCL(XL). | Q45815145 | ||
| To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions. | Q46142204 | ||
| Proapoptotic BID is an ATM effector in the DNA-damage response | Q46669145 | ||
| Bax activation and stress-induced apoptosis delayed by the accumulation of cholesterol in mitochondrial membranes | Q46847162 | ||
| Non-apoptotic role of BID in inflammation and innate immunity | Q50521157 | ||
| Assembly of Bcl-2 into microsomal and outer mitochondrial membranes | Q72331978 | ||
| Cardiolipin provides specificity for targeting of tBid to mitochondria | Q73062575 | ||
| Nonionic detergents induce dimerization among members of the Bcl-2 family | Q73343305 | ||
| Helix 6 of tBid is necessary but not sufficient for mitochondrial binding activity | Q73436542 | ||
| Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies | Q79370601 | ||
| Phylogenomics of life-or-death switches in multicellular animals: Bcl-2, BH3-Only, and BNip families of apoptotic regulators | Q81043167 | ||
| Structure assembly of Bcl-x(L) through alpha5-alpha5 and alpha6-alpha6 interhelix interactions in lipid membranes | Q84569267 | ||
| The Bax carboxy-terminal hydrophobic helix does not determine organelle-specific targeting but is essential for maintaining Bax in an inactive state and for stable mitochondrial membrane insertion | Q84654319 | ||
| Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC | Q22009974 | ||
| PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 | ||
| Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis | Q24291662 | ||
| Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers | Q24292693 | ||
| Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function | Q24293924 | ||
| The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death | Q24294863 | ||
| Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis | Q24296781 | ||
| Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol | Q24298758 | ||
| Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization | Q24300125 | ||
| Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins | Q24302494 | ||
| Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis | Q24306444 | ||
| Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors | Q24310559 | ||
| Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis | Q24310597 | ||
| Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death | Q24312211 | ||
| BID: a novel BH3 domain-only death agonist | Q24320091 | ||
| Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands | Q24321449 | ||
| Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax | Q24323186 | ||
| Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members | Q24337108 | ||
| Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel | Q24523479 | ||
| harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L) | Q24532147 | ||
| Bim: a novel member of the Bcl-2 family that promotes apoptosis | Q24532974 | ||
| Post-transcriptional and post-translational regulation of Bcl2. | Q37813761 | ||
| BH3-only proteins: Orchestrators of apoptosis | Q37819153 | ||
| Autophagy and cancer | Q37967998 | ||
| Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. | Q38268983 | ||
| A unified model of mammalian BCL-2 protein family interactions at the mitochondria. | Q39292731 | ||
| Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells | Q39371756 | ||
| Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival | Q39761203 | ||
| Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. | Q39905589 | ||
| Conformation of the Bax C-terminus regulates subcellular location and cell death | Q24534099 | ||
| Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival | Q24635383 | ||
| Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis | Q24669892 | ||
| An internal EELD domain facilitates mitochondrial targeting of Mcl-1 via a Tom70-dependent pathway | Q24670136 | ||
| Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis | Q24670370 | ||
| Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity | Q24675444 | ||
| Movement of Bax from the Cytosol to Mitochondria during Apoptosis | Q24677881 | ||
| The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity | Q24683846 | ||
| A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast | Q24685400 | ||
| Solution structure of BID, an intracellular amplifier of apoptotic signaling | Q27617719 | ||
| Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists | Q27617723 | ||
| Structure of Bax: coregulation of dimer formation and intracellular localization | Q27628839 | ||
| The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site | Q27640443 | ||
| The structure of a Bcl-xL/Bim fragment complex: implications for Bim function | Q27642185 | ||
| Structural insights into the degradation of Mcl-1 induced by BH3 domains | Q27644256 | ||
| BAX activation is initiated at a novel interaction site | Q27652635 | ||
| Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands | Q27657282 | ||
| Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes | Q27658925 | ||
| The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer | Q27662487 | ||
| X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death | Q27733156 | ||
| Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis | Q27734734 | ||
| Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis | Q28144256 | ||
| BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria | Q28205892 | ||
| Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death | Q28242641 | ||
| BH3 Domain of BAD Is Required for Heterodimerization with BCL-XL and Pro-apoptotic Activity | Q28249553 | ||
| Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K | Q28299861 | ||
| Induction of apoptosis by the Bcl-2 homologue Bak | Q28299871 | ||
| Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak | Q28299882 | ||
| Barrel-stave model or toroidal model? A case study on melittin pores. | Q28346167 | ||
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
| Role of Bax and Bak in mitochondrial morphogenesis | Q28591724 | ||
| MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria | Q28594262 | ||
| Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets | Q28910218 | ||
| Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line | Q29399117 | ||
| Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane | Q29616354 | ||
| BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly | Q29617135 | ||
| Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics | Q29620467 | ||
| Structure of transmembrane pore induced by Bax-derived peptide: evidence for lipidic pores. | Q30157467 | ||
| Pivotal role of Harakiri in the induction and prevention of gentamicin-induced hearing loss | Q30476336 | ||
| Bcl-XL inhibits membrane permeabilization by competing with Bax. | Q33343021 | ||
| Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis | Q33854131 | ||
| Bax forms an oligomer via separate, yet interdependent, surfaces | Q33885192 | ||
| BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions | Q34078104 | ||
| Regulation of Bcl-xL: a little bit of this and a little bit of STAT. | Q34086142 | ||
| The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes | Q34160226 | ||
| Multiple Functions of BCL-2 Family Proteins | Q34326024 | ||
| Mitochondrial carriers and pores: key regulators of the mitochondrial apoptotic program? | Q34621961 | ||
| Measuring and Modeling Apoptosis in Single Cells | Q34921455 | ||
| Bcl-2-family proteins and the role of mitochondria in apoptosis | Q35595911 | ||
| Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl. | Q35687120 | ||
| Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins. | Q35880175 | ||
| A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax. | Q35917067 | ||
| BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins | Q36118310 | ||
| Autophagy and Neuronal Cell Death in Neurological Disorders | Q36329444 | ||
| The permeability transition pore complex in cancer cell death | Q36558006 | ||
| Role of the mitochondrial membrane permeability transition in cell death | Q36669154 | ||
| Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes | Q36799170 | ||
| Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins | Q37068553 | ||
| Regulation of Bcl-2 family proteins by posttranslational modifications. | Q37108448 | ||
| Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation | Q37158414 | ||
| Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members | Q37237621 | ||
| The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor | Q37308429 | ||
| C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1. | Q37431712 | ||
| The autophagy effector Beclin 1: a novel BH3-only protein | Q37566206 | ||
| BAD: undertaker by night, candyman by day. | Q37566231 | ||
| Noxa: at the tip of the balance between life and death. | Q37566236 | ||
| Bid: a Bax-like BH3 protein. | Q37566240 | ||
| Still embedded together binding to membranes regulates Bcl-2 protein interactions. | Q37773789 | ||
| P433 | issue | 4 | |
| P304 | page(s) | a008714 | |
| P577 | publication date | 2013-04-01 | |
| P1433 | published in | Cold Spring Harbor Perspectives in Biology | Q3927509 |
| P1476 | title | Mechanisms of action of Bcl-2 family proteins | |
| P478 | volume | 5 |
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