| scholarly article | Q13442814 |
| P50 | author | Dawid Krokowski | Q70112860 |
| P2093 | author name string | Maria Hatzoglou | |
| Randal J Kaufman | |||
| Anton A Komar | |||
| Mithu Majumder | |||
| Junichi Tanaka | |||
| Martin D Snider | |||
| Charlie Huang | |||
| P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20 | Q24291673 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| All roads lead to ATF4 | Q24299679 | ||
| DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization | Q24302100 | ||
| Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements | Q24310021 | ||
| AU-rich elements and associated factors: are there unifying principles? | Q24535929 | ||
| Endoplasmic reticulum stress: cell life and death decisions. | Q24536108 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing | Q27649529 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| Regulation of translation initiation in eukaryotes: mechanisms and biological targets | Q28111696 | ||
| Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Stress granules: sites of mRNA triage that regulate mRNA stability and translatability | Q28215404 | ||
| Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
| Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation | Q28591523 | ||
| Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
| Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
| Stress-induced gene expression requires programmed recovery from translational repression | Q39735685 | ||
| The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex | Q39751132 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation | Q39897560 | ||
| Regulation of apoptosis by the unfolded protein response. | Q42159220 | ||
| Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. | Q47942024 | ||
| Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies | Q57279989 | ||
| ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum | Q80935578 | ||
| Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II | Q81144490 | ||
| That which does not kill me makes me stronger: adapting to chronic ER stress | Q81405125 | ||
| Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress | Q29615495 | ||
| Translational control in stress and apoptosis | Q29615497 | ||
| The enzymes and control of eukaryotic mRNA turnover | Q29616563 | ||
| Coping with stress: eIF2 kinases and translational control | Q29619787 | ||
| The cap-to-tail guide to mRNA turnover | Q29619835 | ||
| Poly(A) and translation: development control | Q30465625 | ||
| Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering | Q30496639 | ||
| eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress | Q33883278 | ||
| Polysome analysis and RNA purification from sucrose gradients | Q34152997 | ||
| Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise | Q34353133 | ||
| Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2alpha phosphorylation and cap-independent translation. | Q34514695 | ||
| Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function | Q34658630 | ||
| Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation | Q34719370 | ||
| Transcriptional and translational control in the Mammalian unfolded protein response | Q34762452 | ||
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
| The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress. | Q35551757 | ||
| Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response | Q35663586 | ||
| Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR. | Q35962822 | ||
| Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response | Q36322641 | ||
| Protein quality control in the early secretory pathway | Q36446833 | ||
| Hypoxic inhibition of nonsense-mediated RNA decay regulates gene expression and the integrated stress response | Q36711234 | ||
| In a tight spot: ARE-mRNAs at processing bodies. | Q36763439 | ||
| Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the | Q36825517 | ||
| Translational control and the unfolded protein response | Q36924278 | ||
| Temporal regulation of Cat-1 (cationic amino acid transporter-1) gene transcription during endoplasmic reticulum stress | Q36934435 | ||
| The endoplasmic reticulum and the unfolded protein response | Q37006310 | ||
| Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development | Q37100863 | ||
| Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow | Q37176759 | ||
| Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells | Q37388595 | ||
| Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors | Q37622077 | ||
| XBP1: the last two decades | Q37649065 | ||
| Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase | Q37726811 | ||
| Cytoplasmic deadenylation: regulation of mRNA fate | Q37813750 | ||
| Cutting the nonsense: the degradation of PTC-containing mRNAs | Q37813770 | ||
| Inhibition of nonsense-mediated RNA decay by the tumor microenvironment promotes tumorigenesis | Q38284709 | ||
| Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA. | Q39608147 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| cooperation | Q380962 | ||
| P304 | page(s) | 992-1003 | |
| P577 | publication date | 2012-01-03 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation | |
| P478 | volume | 32 |
| Q92626367 | 12-h clock regulation of genetic information flow by XBP1s |
| Q47315154 | A Unique ISR Program Determines Cellular Responses to Chronic Stress. |
| Q26828355 | A molecular mechanism for glaucoma: endoplasmic reticulum stress and the unfolded protein response |
| Q36928959 | A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux |
| Q33743668 | Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress |
| Q35859494 | Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity |
| Q37120369 | Deleterious assembly of the lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy |
| Q53025676 | ER Stress Response in Human Cellular Models of Senescence. |
| Q53825300 | Effect of the unfolded protein response on ER protein export: a potential new mechanism to relieve ER stress. |
| Q36466647 | Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress |
| Q37729222 | Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E. |
| Q92255602 | Herpesviruses and the Unfolded Protein Response |
| Q47236958 | Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance |
| Q37645644 | Interrelation between protein synthesis, proteostasis and life span |
| Q37512312 | Intricately Regulated: A Cellular Toolbox for Fine-Tuning XBP1 Expression and Activity |
| Q27015015 | Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases |
| Q36063732 | Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status |
| Q35841763 | MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response |
| Q37602836 | Molecular signal networks and regulating mechanisms of the unfolded protein response |
| Q53108114 | PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress. |
| Q34995137 | Regulation of sumo mRNA during endoplasmic reticulum stress |
| Q38153592 | Regulatory crosstalk within the mammalian unfolded protein response |
| Q41823803 | Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human |
| Q37692466 | Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer |
| Q34807567 | The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells |
| Q92288072 | The role of the XBP-1/AGR2 signaling pathway in the regulation of airway Mucin5ac hypersecretion under hypoxia |
| Q33556172 | Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α. |
| Q64100162 | Widespread PERK-dependent repression of ER targets in response to ER stress |
| Q41195914 | eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet |
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