| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Rong Wu | |
| Guang-Hui Yi | |||
| Qing-Hai Zhang | |||
| Kun Ren | |||
| Yan-Ju Lu | |||
| P2860 | cites work | X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes | Q43156368 |
| Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver | Q43194435 | ||
| Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats | Q43274869 | ||
| Molecular analysis of endoplasmic reticulum stress response after global forebrain ischemia/reperfusion in rats: effect of neuroprotectant simvastatin. | Q43712349 | ||
| Regulated IRE1-dependent decay participates in curtailing immunoglobulin secretion from plasma cells | Q45387412 | ||
| Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. | Q47942024 | ||
| Protective effects of XBP1 against oxygen and glucose deprivation/reoxygenation injury in rat primary hippocampal neurons | Q48516313 | ||
| Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARα axis signalling. | Q51324999 | ||
| In situ hybridization studies suggest a role for the basic region‐leucine zipper protein hXBP‐1 in exocrine gland and skeletal development during mouse embryogenesis | Q52224944 | ||
| Mild endoplasmic reticulum stress augments the proinflammatory effect of IL-1β in pancreatic rat β-cells via the IRE1α/XBP1s pathway. | Q54515304 | ||
| Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes | Q64377708 | ||
| Sarcalumenin plays a critical role in age-related cardiac dysfunction due to decreases in SERCA2a expression and activity | Q82690537 | ||
| Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development | Q24292104 | ||
| The unfolded protein response: integrating stress signals through the stress sensor IRE1α | Q24293771 | ||
| pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response | Q24303865 | ||
| XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation | Q24304996 | ||
| A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response | Q24305069 | ||
| SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth | Q24309283 | ||
| Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis | Q24337309 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| Ligand-independent activation of estrogen receptor alpha by XBP-1 | Q24678871 | ||
| The unfolded protein response signals through high-order assembly of Ire1 | Q27653139 | ||
| Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA. | Q39608147 | ||
| XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum | Q39659690 | ||
| Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation | Q39770218 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis | Q39843795 | ||
| pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation. | Q39898784 | ||
| Compartmentalized expression of three novel sarco/endoplasmic reticulum Ca2+ATPase 3 isoforms including the switch to ER stress, SERCA3f, in non-failing and failing human heart. | Q39926129 | ||
| XBP-1 increases ERalpha transcriptional activity through regulation of large-scale chromatin unfolding | Q40518478 | ||
| XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. | Q40519913 | ||
| A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism | Q41762089 | ||
| A stress signaling pathway in adipose tissue regulates hepatic insulin resistance | Q41811449 | ||
| ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis. | Q41948428 | ||
| Estrogen regulation of X-box binding protein-1 and its role in estrogen induced growth of breast and endometrial cancer cells | Q42180992 | ||
| The unfolded protein response is an important regulator of inflammatory genes in endothelial cells | Q42500350 | ||
| Oxidized low density lipoprotein induces macrophage endoplasmic reticulum stress via CD36 | Q42859537 | ||
| Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeast | Q27936119 | ||
| A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter | Q28119099 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation | Q28240596 | ||
| JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity | Q28256254 | ||
| Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis | Q28275274 | ||
| Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
| Maturational disturbance of chondrocytes in Cbfa1-deficient mice | Q28506259 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver | Q28577788 | ||
| Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex | Q28585312 | ||
| The role of adipocyte XBP1 in metabolic regulation during lactation | Q28587096 | ||
| XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
| Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
| Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts | Q29547605 | ||
| A central role for JNK in obesity and insulin resistance | Q29619778 | ||
| Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic program | Q30426645 | ||
| Prevention of steatosis by hepatic JNK1 | Q33580974 | ||
| BRD7 regulates XBP1s' activity and glucose homeostasis through its interaction with the regulatory subunits of PI3K | Q33838482 | ||
| SLC33A1/AT-1 protein regulates the induction of autophagy downstream of IRE1/XBP1 pathway | Q34287569 | ||
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
| Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1. | Q34575640 | ||
| Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN. | Q34882666 | ||
| Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
| Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro. | Q35088080 | ||
| Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress | Q35213294 | ||
| p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis | Q35419603 | ||
| Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice | Q35709954 | ||
| A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation | Q35807258 | ||
| The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance | Q35856767 | ||
| Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy | Q35909430 | ||
| The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells. | Q35981133 | ||
| Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
| XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells | Q36402768 | ||
| The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism | Q36497151 | ||
| IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis | Q36600595 | ||
| ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice | Q36709748 | ||
| XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells | Q36739979 | ||
| Potential for therapeutic manipulation of the UPR in disease | Q36809416 | ||
| Activation of PPARα ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress. | Q36867522 | ||
| X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function | Q37015048 | ||
| IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Q37091581 | ||
| Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages | Q37170709 | ||
| GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
| Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow | Q37176759 | ||
| From endoplasmic-reticulum stress to the inflammatory response | Q37225354 | ||
| Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
| A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size | Q37368338 | ||
| Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila | Q37381743 | ||
| Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection. | Q37418550 | ||
| The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response | Q37430626 | ||
| Unfolded protein response signaling and metabolic diseases | Q37488392 | ||
| Endoplasmic reticulum stress promotes macrophage-derived foam cell formation by up-regulating cluster of differentiation 36 (CD36) expression | Q37583467 | ||
| Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis | Q37597070 | ||
| Emerging roles for XBP1, a sUPeR transcription factor | Q37808199 | ||
| Stressed out about obesity: IRE1α-XBP1 in metabolic disorders | Q37894253 | ||
| Adiponectin: mechanistic insights and clinical implications | Q38017897 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| Identification of a consensus element recognized and cleaved by IRE1 alpha. | Q38343711 | ||
| Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification. | Q38768448 | ||
| Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells | Q39148101 | ||
| Activating transcription factor 6 mediates oxidized LDL-induced cholesterol accumulation and apoptosis in macrophages by up-regulating CHOP expression | Q39265612 | ||
| Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress | Q39321586 | ||
| Minimally modified low-density lipoprotein induces macrophage endoplasmic reticulum stress via toll-like receptor 4. | Q39368723 | ||
| IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. | Q39422225 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6-18 | |
| P577 | publication date | 2015-01-01 | |
| P1433 | published in | DNA and Cell Biology | Q5205740 |
| P1476 | title | Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases | |
| P478 | volume | 34 |
| Q61451234 | Berberine, a Traditional Chinese Medicine, Reduces Inflammation in Adipose Tissue, Polarizes M2 Macrophages, and Increases Energy Expenditure in Mice Fed a High-Fat Diet |
| Q38785751 | Critical role of X-box binding protein 1 in NADPH oxidase 4-triggered cardiac hypertrophy is mediated by receptor interacting protein kinase 1. |
| Q36026996 | Dendritic cells are stressed out in tumor |
| Q64258921 | Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance |
| Q53816612 | Expression of XBP1s in fibroblasts is critical for TiAl6 V4 particle-induced RANKL expression and osteolysis. |
| Q92932318 | Foie gras and liver regeneration: a fat dilemma |
| Q57288911 | IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages |
| Q42677134 | IRE1α/XBP1s branch of UPR links HIF1α activation to mediate ANGII-dependent endothelial dysfunction under particulate matter (PM) 2.5 exposure |
| Q90074418 | Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation |
| Q33838535 | Knockdown of XBP1 by RNAi in Mouse Granulosa Cells Promotes Apoptosis, Inhibits Cell Cycle, and Decreases Estradiol Synthesis |
| Q47256903 | Real-Time and Non-invasive Monitoring of the Activation of the IRE1α-XBP1 Pathway in Individuals with Hemodynamic Impairment |
| Q89805218 | Regulation of Adipsin Expression by Endoplasmic Reticulum Stress in Adipocytes |
| Q48708732 | Systemic effects of AGEs in ER stress induction in vivo |
| Q89552648 | The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias |
| Q38777795 | Tumor-derived factors modulating dendritic cell function |
| Q91690530 | Upregulation of miR-34a by Inhibition of IRE1α Has Protective Effect against Aβ-Induced Injury in SH-SY5Y Cells by Targeting Caspase-2 |
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