| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Ling Qi | Q37375214 |
| P2093 | author name string | Haibo Sha | |
| Liu Yang | |||
| Yin He | |||
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
| A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells | Q24297587 | ||
| ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
| Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation | Q24303825 | ||
| A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response | Q24305069 | ||
| SUMO modification regulates the transcriptional activity of XBP1 | Q24307512 | ||
| BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha | Q24310536 | ||
| Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
| Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages | Q24594623 | ||
| Endoplasmic reticulum stress and the inflammatory basis of metabolic disease | Q24633352 | ||
| XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy | Q24655821 | ||
| The protein kinase IKKepsilon regulates energy balance in obese mice | Q24658201 | ||
| IRE1-independent gain control of the unfolded protein response | Q24798921 | ||
| Autophagy in the Pathogenesis of Disease | Q27860558 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307) | Q28139056 | ||
| Signal transduction by the JNK group of MAP kinases | Q28142592 | ||
| JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity | Q28256254 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| An initial blueprint for myogenic differentiation | Q28588060 | ||
| IKK-beta links inflammation to obesity-induced insulin resistance | Q29614285 | ||
| Autophagy is activated for cell survival after endoplasmic reticulum stress | Q29614485 | ||
| Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
| TLR4 links innate immunity and fatty acid-induced insulin resistance | Q29617577 | ||
| A central role for JNK in obesity and insulin resistance | Q29619778 | ||
| Regulated increase in folding capacity prevents unfolded protein stress in the ER. | Q30977675 | ||
| Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance | Q33556664 | ||
| Prevention of steatosis by hepatic JNK1 | Q33580974 | ||
| A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress | Q33641274 | ||
| Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance | Q33673551 | ||
| An essential role for XBP-1 in host protection against immune activation in C. elegans | Q33710158 | ||
| Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. | Q33896647 | ||
| XBP-1 couples endoplasmic reticulum stress to augmented IFN-beta induction via a cis-acting enhancer in macrophages. | Q34047912 | ||
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
| Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
| Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN. | Q34882666 | ||
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
| The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance | Q35856767 | ||
| XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
| Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1 | Q36366273 | ||
| Functionality of unspliced XBP1 is required to explain evolution of overlapping reading frames | Q36620957 | ||
| Innate host defense: Nox and Duox on phox's tail | Q36835213 | ||
| Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity | Q36981204 | ||
| GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
| Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
| Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis | Q37465347 | ||
| Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome | Q37596032 | ||
| ER stress in pancreatic beta cells: the thin red line between adaptation and failure | Q37697386 | ||
| Toll-like receptors: linking inflammation to metabolism | Q37796144 | ||
| Emerging roles for XBP1, a sUPeR transcription factor | Q37808199 | ||
| The binary switch that controls the life and death decisions of ER stressed β cells | Q37822114 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| Identification of a consensus element recognized and cleaved by IRE1 alpha. | Q38343711 | ||
| Detecting and quantitating physiological endoplasmic reticulum stress | Q39789909 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis | Q39843795 | ||
| Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
| The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes. | Q40453939 | ||
| A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism | Q41762089 | ||
| The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis | Q41791624 | ||
| A stress signaling pathway in adipose tissue regulates hepatic insulin resistance | Q41811449 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Irs1 serine 307 promotes insulin sensitivity in mice | Q42563623 | ||
| Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver | Q43194435 | ||
| Involvement of endoplasmic reticulum stress in insulin resistance and diabetes | Q45127777 | ||
| Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 | ||
| Direct monitoring of in vivo ER stress during the development of insulin resistance with ER stress-activated indicator transgenic mice. | Q46857277 | ||
| P433 | issue | 9 | |
| P921 | main subject | obesity | Q12174 |
| P304 | page(s) | 374-381 | |
| P577 | publication date | 2011-06-22 | |
| P1433 | published in | Trends in Endocrinology and Metabolism | Q15265727 |
| P1476 | title | Stressed out about obesity: IRE1α-XBP1 in metabolic disorders | |
| P478 | volume | 22 |
| Q64980705 | Abnormal Glucose Metabolism and Insulin Resistance Are Induced via the IRE1α/XBP-1 Pathway in Subclinical Hypothyroidism. |
| Q37597070 | Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis |
| Q35196985 | Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy |
| Q36634922 | Elimination of endoplasmic reticulum stress and cardiovascular, type 2 diabetic, and other metabolic diseases |
| Q47232868 | Embedded in the Membrane: How Lipids Confer Activity and Specificity to Intramembrane Proteases |
| Q38385700 | Endoplasmic reticulum quality control in cancer: Friend or foe. |
| Q27027733 | Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases |
| Q53816612 | Expression of XBP1s in fibroblasts is critical for TiAl6 V4 particle-induced RANKL expression and osteolysis. |
| Q52718679 | Glucose-regulated protein 78 is essential for cardiac myocyte survival. |
| Q39986343 | IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma |
| Q40321206 | IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes |
| Q36040437 | IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis |
| Q27015015 | Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases |
| Q64248921 | Mechanisms of Acupuncture Therapy for Simple Obesity: An Evidence-Based Review of Clinical and Animal Studies on Simple Obesity |
| Q33699810 | Mechanisms of inflammatory responses in obese adipose tissue |
| Q90421228 | Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress |
| Q39107838 | New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation |
| Q36540356 | Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. |
| Q37670086 | Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance |
| Q36832660 | Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner. |
| Q33653691 | Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease |
| Q56396155 | Role of autophagy in a model of obesity: A long‑term high fat diet induces cardiac dysfunction |
| Q92035617 | Role of ghrelin isoforms in the mitigation of hepatic inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress after bariatric surgery in rats |
| Q90435275 | Rotavirus Infection Alters Splicing of the Stress-Related Transcription Factor XBP1 |
| Q42334839 | Sigmar1 regulates endoplasmic reticulum stress-induced C/EBP-homologous protein expression in cardiomyocytes |
| Q36330343 | Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. |
| Q40258446 | Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes |
| Q39446306 | The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development |
| Q57792065 | The cyclic phosphodiesterase CNP and RNA cyclase RtcA fine-tune noncanonical XBP1 splicing during ER stress |
| Q58185753 | The nucleotide exchange factor SIL1 is required for glucose-stimulated insulin secretion from mouse pancreatic beta cells in vivo |
| Q58702700 | The unfolded protein response signaling and retinal Müller cell metabolism |
| Q28589300 | Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis |
| Q102206214 | Winter is coming: Regulation of cellular metabolism by enzyme polymerization in dormancy and disease |
| Q42820945 | X-box binding protein 1 enhances adipogenic differentiation of 3T3-L1 cells through the downregulation of Wnt10b expression |
| Q42835425 | X-box binding protein 1 is a novel key regulator of peroxisome proliferator-activated receptor γ2. |
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