SUMO modification regulates the transcriptional activity of XBP1

scientific article

SUMO modification regulates the transcriptional activity of XBP1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ20100193
P932PMC publication ID2964647
P698PubMed publication ID20408817
P5875ResearchGate publication ID43246038

P50authorLing QiQ37375214
P2093author name stringHui Chen
P2860cites workSUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisationQ22008651
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
Plasma cell differentiation requires the transcription factor XBP-1Q24291453
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans developmentQ24292104
The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT coreQ24317656
Histone sumoylation is associated with transcriptional repressionQ24656259
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein responseQ24672592
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
System-wide changes to SUMO modifications in response to heat shockQ27865236
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleusQ27930818
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein responseQ27933479
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein responseQ27938493
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinaseQ27938837
tRNA ligase is required for regulated mRNA splicing in the unfolded protein responseQ27940124
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activityQ28117824
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
SUMO: a history of modificationQ28243325
PIAS proteins: pleiotropic interactors associated with SUMOQ28248545
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1Q28507338
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glandsQ28510479
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
An essential role in liver development for transcription factor XBP-1Q28593777
Protein modification by SUMOQ29547919
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunitiesQ29617768
SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targetingQ29619527
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.Q33777806
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiationQ34345459
ER stress and diseases.Q36731474
Targeted disruption of CRE-binding factor TREB5 gene leads to cellular necrosis in cardiac myocytes at the embryonic stageQ38322371
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesisQ39843795
SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-deltaQ39979150
SUMO promotes HDAC-mediated transcriptional repressionQ48017954
p300 Transcriptional Repression Is Mediated by SUMO ModificationQ60304936
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
Histone deacetylase 5Q5773160
transcription factor bindingQ14817982
Protein inhibitor of activated STAT 2Q21115153
Protein inhibitor of activated STAT 2Q21981323
P304page(s)95-102
P577publication date2010-07-01
P1433published inBiochemical JournalQ864221
P1476titleSUMO modification regulates the transcriptional activity of XBP1
P478volume429

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cites work (P2860)
Q33641274A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress
Q35183001A conserved structural determinant located at the interdomain region of mammalian inositol-requiring enzyme 1alpha
Q42164082An atypical unfolded protein response in heat shocked cells
Q37848749Ca2+-signaling, alternative splicing and endoplasmic reticulum stress responses
Q37808199Emerging roles for XBP1, a sUPeR transcription factor
Q42350805Erratum: Proteostasis control by the unfolded protein response
Q91720997Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies
Q47133560Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response.
Q37512312Intricately Regulated: A Cellular Toolbox for Fine-Tuning XBP1 Expression and Activity
Q35841763MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response
Q38540196Proteostasis control by the unfolded protein response
Q34995137Regulation of sumo mRNA during endoplasmic reticulum stress
Q24303825Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation
Q90435275Rotavirus Infection Alters Splicing of the Stress-Related Transcription Factor XBP1
Q47614965SUMOylation represses the transcriptional activity of the Unfolded Protein Response transducer ATF6.
Q37894253Stressed out about obesity: IRE1α-XBP1 in metabolic disorders
Q39107046Sub-cellular localization specific SUMOylation in the heart
Q38535130Sumo and the cellular stress response
Q47799714Sumoylation: Implications for Neurodegenerative Diseases
Q91807286The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation
Q38093057The role of the unfolded protein response in diabetes mellitus
Q29615499The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Q24293771The unfolded protein response: integrating stress signals through the stress sensor IRE1α
Q35122358UPR, autophagy, and mitochondria crosstalk underlies the ER stress response
Q34047912XBP-1 couples endoplasmic reticulum stress to augmented IFN-beta induction via a cis-acting enhancer in macrophages.
Q26998690Xenobiotic perturbation of ER stress and the unfolded protein response

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