review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1177/0192623312470764 |
P8608 | Fatcat ID | release_uqui6ttlzndybjkiqrqwcl5qz4 |
P698 | PubMed publication ID | 23334697 |
P5875 | ResearchGate publication ID | 234702387 |
P2093 | author name string | J. L. Stevens | |
J. W. Lawrence | |||
M. A. Lafleur | |||
P2860 | cites work | HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction | Q21145793 |
CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins | Q22010670 | ||
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta | Q22011091 | ||
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 | ||
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity | Q24290192 | ||
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress | Q24291026 | ||
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK | Q24296386 | ||
Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress | Q24296809 | ||
A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells | Q24297587 | ||
Proapoptotic BAX and BAK control multiple initiator caspases | Q24298402 | ||
JAB1 participates in unfolded protein responses by association and dissociation with IRE1 | Q24298558 | ||
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells | Q24299603 | ||
Luman is capable of binding and activating transcription from the unfolded protein response element | Q24300509 | ||
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12 | Q24300914 | ||
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells | Q24301679 | ||
Roles of CHOP/GADD153 in endoplasmic reticulum stress | Q24302185 | ||
Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation | Q24303825 | ||
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response | Q24303865 | ||
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response | Q24304232 | ||
SUMO modification regulates the transcriptional activity of XBP1 | Q24307512 | ||
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha | Q24310536 | ||
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response | Q24314664 | ||
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha | Q24320638 | ||
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer | Q24337349 | ||
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death | Q24338605 | ||
CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P. | Q24338672 | ||
Endoplasmic reticulum stress: cell life and death decisions. | Q24536108 | ||
Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. | Q24541469 | ||
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma | Q24600346 | ||
ER stress controls iron metabolism through induction of hepcidin | Q24630714 | ||
Ca(2+) transfer from the ER to mitochondria: when, how and why | Q24647997 | ||
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival | Q24653078 | ||
XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells | Q24658399 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
Oxidative protein folding in eukaryotes: mechanisms and consequences | Q24676827 | ||
Road to ruin: targeting proteins for degradation in the endoplasmic reticulum | Q26866096 | ||
Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations. | Q38361754 | ||
Upregulation and overexpression of human X-box binding protein 1 (hXBP-1) gene in primary breast cancers | Q38449959 | ||
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1. | Q38947838 | ||
Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK | Q39142751 | ||
IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. | Q39422225 | ||
Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition | Q39435523 | ||
Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cells | Q39495353 | ||
Salubrinal, an eIF2α dephosphorylation inhibitor, enhances cisplatin-induced oxidative stress and nephrotoxicity in a mouse model. | Q39535847 | ||
Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction | Q39642134 | ||
XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum | Q39659690 | ||
Apigenin protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis | Q39701311 | ||
Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets. | Q39751051 | ||
Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferation | Q39769768 | ||
MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP. | Q39772786 | ||
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation. | Q39898784 | ||
Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis | Q39958648 | ||
Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. | Q39962425 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins | Q40015897 | ||
Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition | Q40120317 | ||
Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines | Q40148265 | ||
Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes | Q40176269 | ||
SIRT1 associates with eIF2-alpha and regulates the cellular stress response | Q40184948 | ||
Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response | Q40210691 | ||
Assays for detecting the unfolded protein response. | Q54617608 | ||
Measurement of ER stress response and inflammation in the mouse model of nonalcoholic fatty liver disease. | Q54617615 | ||
Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells. | Q55475244 | ||
Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes | Q59167170 | ||
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells | Q28513964 | ||
Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain | Q28572076 | ||
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons | Q28573805 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis | Q28576685 | ||
Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells | Q28578375 | ||
Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner | Q28580378 | ||
OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes | Q28580776 | ||
The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers | Q28581980 | ||
Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex | Q28582404 | ||
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway | Q28583302 | ||
Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus | Q28584118 | ||
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis | Q28586997 | ||
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress | Q28592598 | ||
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
The mammalian unfolded protein response | Q29547400 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls | Q29547730 | ||
Autophagy is activated for cell survival after endoplasmic reticulum stress | Q29614485 | ||
Impairment of the ubiquitin-proteasome system by protein aggregation | Q29614556 | ||
IRE1 signaling affects cell fate during the unfolded protein response | Q29615502 | ||
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
Translocation of proteins into mitochondria | Q29616478 | ||
ER stress triggers apoptosis by activating BH3-only protein Bim | Q29617730 | ||
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities | Q29617768 | ||
Setting the standards: quality control in the secretory pathway | Q29620321 | ||
Protein import into mitochondria | Q29620420 | ||
Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces | Q30039723 | ||
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering | Q30496639 | ||
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins | Q33262919 | ||
Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway | Q33264756 | ||
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response | Q33264844 | ||
Small molecule regulators of autophagy identified by an image-based high-throughput screen | Q33306309 | ||
Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94 | Q33397723 | ||
In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation | Q33583065 | ||
IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level | Q33707431 | ||
The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans | Q33757350 | ||
Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response | Q33838972 | ||
How an inhibitor of the HIV-I protease modulates proteasome activity | Q33882609 | ||
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. | Q33960826 | ||
Hyperthermia induces the ER stress pathway | Q34005542 | ||
Ryanodine receptors: structure, expression, molecular details, and function in calcium release. | Q34024377 | ||
Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine | Q34103511 | ||
Wolcott-Rallison syndrome | Q34148057 | ||
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis | Q34169287 | ||
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling | Q34179244 | ||
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis | Q34192744 | ||
Mitochondrial calcium signaling driven by the IP3 receptor | Q34478937 | ||
Drug-related hepatotoxicity | Q34495071 | ||
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. | Q34626231 | ||
Divergent effects of PERK and IRE1 signaling on cell viability | Q27438124 | ||
Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P | Q27681837 | ||
Autophagy in the Pathogenesis of Disease | Q27860558 | ||
RNA-mediated response to heat shock in mammalian cells | Q28118457 | ||
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex | Q28118708 | ||
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response | Q28139601 | ||
Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis | Q28142928 | ||
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells | Q28155919 | ||
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis | Q28189945 | ||
Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
Mechanisms of hepatotoxicity | Q28216749 | ||
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis | Q28258427 | ||
A molecular chaperone inducer protects neurons from ER stress | Q28259344 | ||
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms | Q28260472 | ||
N-glycan processing in ER quality control | Q28271200 | ||
Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis | Q28277961 | ||
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase | Q28280649 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
The dsRNA protein kinase PKR: virus and cell control | Q28298945 | ||
Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase | Q28299534 | ||
The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group | Q28299691 | ||
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress | Q28306995 | ||
ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells | Q28307506 | ||
Regulation of HSF1 function in the heat stress response: implications in aging and disease | Q28307651 | ||
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice | Q28359871 | ||
Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload | Q28506232 | ||
Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress | Q28506667 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells | Q28508342 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
The unfolded protein response in nutrient sensing and differentiation | Q34664763 | ||
Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo | Q34676901 | ||
Regulation of ER stress proteins by valproate: therapeutic implications. | Q34692778 | ||
Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress | Q34698161 | ||
HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress. | Q34714150 | ||
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response | Q35170906 | ||
A review of the mammalian unfolded protein response. | Q35354864 | ||
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis | Q35419603 | ||
Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression | Q35552863 | ||
Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells. | Q35681914 | ||
Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells | Q35838863 | ||
Β-adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis | Q35872556 | ||
ER chaperone functions during normal and stress conditions | Q35885336 | ||
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability | Q35916071 | ||
The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress | Q35950143 | ||
The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells. | Q35981133 | ||
Endoplasmic reticulum stress in liver disease | Q36031838 | ||
Membrane biogenesis during B cell differentiation: most endoplasmic reticulum proteins are expressed coordinately | Q36383421 | ||
Quality control of mitochondria: protection against neurodegeneration and ageing | Q36446844 | ||
The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control | Q36598776 | ||
An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses | Q36638199 | ||
Activating transcription factor 4. | Q36805075 | ||
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Q36861224 | ||
Endoplasmic reticulum stress as a novel therapeutic target in heart diseases | Q36952146 | ||
Antioxidants reduce endoplasmic reticulum stress and improve protein secretion | Q36985084 | ||
Endoplasmic reticulum stress and liver injury | Q36989688 | ||
The endoplasmic reticulum and the unfolded protein response | Q37006310 | ||
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy | Q37075287 | ||
Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli. | Q37112625 | ||
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review | Q37130104 | ||
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells | Q37181198 | ||
From endoplasmic-reticulum stress to the inflammatory response | Q37225354 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase | Q37314375 | ||
Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. | Q37433487 | ||
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis | Q37465347 | ||
Caspases and kinases in a death grip | Q37593693 | ||
Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome | Q37596032 | ||
Endoplasmic reticulum stress in proteinuric kidney disease | Q37610753 | ||
Endoplasmic reticulum stress and the unfolded protein response | Q37612124 | ||
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2 | Q37622629 | ||
Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia | Q37627091 | ||
Endoplasmic reticulum stress as a progression factor for kidney injury | Q37666123 | ||
Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM). | Q37739513 | ||
An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin | Q37786866 | ||
The heat shock factor family and adaptation to proteotoxic stress | Q37800068 | ||
Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms. | Q37802039 | ||
The mitochondrial UPR - protecting organelle protein homeostasis | Q37806885 | ||
Bax inhibitor 1 in apoptosis and disease. | Q37836378 | ||
Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressor. | Q37877541 | ||
A diversity of SERCA Ca2+ pump inhibitors | Q37877759 | ||
Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis | Q37878020 | ||
Mechanisms of ER stress-induced apoptosis in atherosclerosis | Q37957844 | ||
Role of endoplasmic reticulum stress in metabolic disease and other disorders. | Q37976132 | ||
Activation of the unfolded protein response is an early event in Alzheimer's and Parkinson's disease. | Q37981067 | ||
Sensing endoplasmic reticulum stress | Q37991599 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Effect on tumor cells of blocking survival response to glucose deprivation | Q38337197 | ||
Regulation of autophagy by ATF4 in response to severe hypoxia. | Q38343634 | ||
Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder | Q38350959 | ||
Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells | Q40310345 | ||
Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis | Q40339610 | ||
Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells | Q40339637 | ||
Heat shock protein 72 protects insulin-secreting beta cells from lipopolysaccharide-induced endoplasmic reticulum stress | Q40371176 | ||
Modulating the endoplasmic reticulum stress response with trans-4,5-dihydroxy-1,2-dithiane prevents chemically induced renal injury in vivo | Q40375854 | ||
Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. | Q40483325 | ||
Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis | Q40558204 | ||
Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response | Q40590374 | ||
Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions. | Q40632735 | ||
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion | Q40669445 | ||
Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation | Q40793113 | ||
Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells | Q41092630 | ||
Caspases: intracellular signaling by proteolysis | Q41656258 | ||
A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response | Q41711854 | ||
Measuring ER stress and the unfolded protein response using mammalian tissue culture system | Q41898554 | ||
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis | Q41904044 | ||
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis | Q42004487 | ||
Human immunodeficiency virus protease inhibitors modulate Ca2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes | Q42037562 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling | Q42045464 | ||
Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL. | Q42115123 | ||
Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress | Q42163338 | ||
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | Q42451739 | ||
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells | Q42500350 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion | Q42588208 | ||
cis-acting sequences involved in the translational control of GCN4 expression | Q42633634 | ||
The antioxidant edaravone attenuates ER-stress-mediated cardiac apoptosis and dysfunction in rats with autoimmune myocarditis | Q42918164 | ||
Inhibition of hepatic carnitine palmitoyl-transferase I (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis | Q43255616 | ||
Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats | Q43274869 | ||
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis | Q43579795 | ||
Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK. | Q43627961 | ||
Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation | Q44015045 | ||
Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation | Q44135113 | ||
Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons | Q44258606 | ||
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis | Q44485247 | ||
A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice | Q46070173 | ||
Up regulation of the GRP-78 and GADD-153 and down regulation of Bcl-2 proteins in primary glomerular diseases: a possible involvement of the ER stress pathway in glomerulonephritis | Q46184114 | ||
Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression. | Q46184567 | ||
Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: a role for endothelial phenotypic changes and death | Q46262369 | ||
Cyclosporine-induced endoplasmic reticulum stress triggers tubular phenotypic changes and death | Q46373887 | ||
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis | Q46434986 | ||
Presence of the functional CASPASE-12 allele in Indian subpopulations | Q46562085 | ||
Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis | Q46695184 | ||
Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells | Q46736495 | ||
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity | Q46765805 | ||
CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury | Q46823993 | ||
ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans | Q47069058 | ||
The unfolded protein response in health and disease | Q47682274 | ||
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. | Q47942024 | ||
Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin. | Q50797144 | ||
The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development. | Q51899074 | ||
Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis. | Q52569822 | ||
Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells. | Q53227756 | ||
Endoplasmic reticulum stress in the kidney as a novel mediator of kidney injury. | Q53402529 | ||
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. | Q53616050 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 235-62 | |
P577 | publication date | 2013-02-01 | |
P1433 | published in | Toxicologic Pathology | Q7830407 |
P1476 | title | Xenobiotic perturbation of ER stress and the unfolded protein response | |
P478 | volume | 41 |
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