scholarly article | Q13442814 |
P2093 | author name string | Joseph W Brewer | |
Andrew E Byrd | |||
P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response | Q24290935 | ||
Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development | Q24292104 | ||
Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation | Q24303825 | ||
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response | Q24303865 | ||
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response | Q24305069 | ||
SUMO modification regulates the transcriptional activity of XBP1 | Q24307512 | ||
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response | Q24316572 | ||
ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum | Q80935578 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control | Q24522941 | ||
MicroRNAs: target recognition and regulatory functions | Q24609584 | ||
A CHOP-regulated microRNA controls rhodopsin expression | Q24632859 | ||
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease | Q24633352 | ||
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter | Q28119099 | ||
Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells | Q28155919 | ||
Comprehensive identification of human bZIP interactions with coiled-coil arrays | Q28178993 | ||
Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
SUMO: a history of modification | Q28243325 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 | Q28507338 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
The transcription factor XBP-1 is essential for the development and survival of dendritic cells | Q28512302 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
Cloning of mammalian Ire1 reveals diversity in the ER stress responses | Q28587224 | ||
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response | Q28589998 | ||
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress | Q29615495 | ||
Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation | Q34148249 | ||
ER stress negatively modulates the expression of the miR-199a/214 cluster to regulates tumor survival and progression in human hepatocellular cancer | Q34168267 | ||
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes. | Q34224697 | ||
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
The role of FoxO in the regulation of metabolism. | Q34768157 | ||
Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses | Q35169632 | ||
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis | Q35419603 | ||
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation | Q35770614 | ||
A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation | Q35807258 | ||
MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response | Q35841763 | ||
Targeting XBP-1 as a novel anti-cancer strategy. | Q36544398 | ||
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2 | Q37622629 | ||
XBP1: the last two decades | Q37649065 | ||
Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA. | Q39608147 | ||
Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation | Q39770218 | ||
pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation. | Q39898784 | ||
Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress | Q40286509 | ||
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. | Q40519913 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. | Q47942024 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 4 | |
P304 | page(s) | 738-753 | |
P577 | publication date | 2012-10-15 | |
P1433 | published in | Cells | Q27724621 |
P1476 | title | Intricately Regulated: A Cellular Toolbox for Fine-Tuning XBP1 Expression and Activity | |
P478 | volume | 1 |
Q43431148 | Crosstalk between the unfolded protein response and pathways that regulate pathogenic development in Ustilago maydis. |
Q92188856 | ER Stress and the UPR in Shaping Intestinal Tissue Homeostasis and Immunity |
Q37564660 | Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways |
Q89743106 | Repression of viral gene expression and replication by the unfolded protein response effector XBP1u |
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