Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis

scientific article

Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2337/DB13-1067
P932PMC publication ID3931404
P698PubMed publication ID24241534
P5875ResearchGate publication ID258636679

P50authorLing QiQ37375214
Sander KerstenQ38320639
P2093author name stringFeng Liu
Yong Liu
Haibo Sha
Liu Yang
Sheng Xia
Meilian Liu
P2860cites workXBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
Plasma cell differentiation requires the transcription factor XBP-1Q24291453
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
The unfolded protein response: integrating stress signals through the stress sensor IRE1αQ24293771
Endoplasmic reticulum stress and the inflammatory basis of metabolic diseaseQ24633352
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagyQ24655821
Adiponectin, driver or passenger on the road to insulin sensitivity?Q26827971
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
Endogenous glucose production is inhibited by the adipose-derived protein Acrp30Q28366672
The adipocyte-secreted protein Acrp30 enhances hepatic insulin actionQ28505765
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesityQ28506782
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1Q28507338
Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30)Q28507473
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocationQ28510062
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glandsQ28510479
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
The role of adipocyte XBP1 in metabolic regulation during lactationQ28587096
Regulation of glucose homeostasis through a XBP-1-FoxO1 interactionQ28592129
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
The unfolded protein response: controlling cell fate decisions under ER stress and beyondQ29615499
Biological and chemical approaches to diseases of proteostasis deficiencyQ29616633
Regulated increase in folding capacity prevents unfolded protein stress in the ER.Q30977675
A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stressQ33641274
DsbA-L alleviates endoplasmic reticulum stress-induced adiponectin downregulationQ34237653
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.Q35041384
Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention.Q35856946
Obesity-associated improvements in metabolic profile through expansion of adipose tissueQ35945161
Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha.Q35948127
The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissueQ35976791
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.Q36330343
The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolismQ36497151
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasisQ36600595
ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in miceQ36709748
DsbA-L is a versatile player in adiponectin secretionQ36985048
A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerizationQ36985272
Mechanisms of adiponectin regulation and use as a pharmacological targetQ37784586
Stressed out about obesity: IRE1α-XBP1 in metabolic disordersQ37894253
Adiponectin: mechanistic insights and clinical implicationsQ38017897
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosisQ38361016
Detecting and quantitating physiological endoplasmic reticulum stressQ39789909
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesisQ39843795
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivityQ40681900
Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.Q42798975
Introduction of DNA into 3T3-L1 adipocytes by electroporationQ42804557
X-box binding protein 1 enhances adipogenic differentiation of 3T3-L1 cells through the downregulation of Wnt10b expressionQ42820945
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivityQ42832775
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivityQ42834758
Adipocyte CREB promotes insulin resistance in obesityQ43065389
Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetesQ44909485
Serum high molecular weight complex of adiponectin correlates better with glucose tolerance than total serum adiponectin in Indo-Asian malesQ46497673
Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjectsQ47287460
Comparison of serum high-molecular weight (HMW) adiponectin with total adiponectin concentrations in type 2 diabetic patients with coronary artery disease using a novel enzyme-linked immunosorbent assay to detect HMW adiponectinQ47331999
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
P1104number of pages13
P304page(s)867-879
P577publication date2013-11-15
P1433published inDiabetesQ895262
P1476titleAdipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis
P478volume63

Reverse relations

cites work (P2860)
Q51245026Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.
Q90537548Adipose tissue dendritic cells in steady-state
Q33921242Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice
Q42362670Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease
Q27015015Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases
Q39014996Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance
Q28594858The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism
Q58778511The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity
Q28084054The cell biology of fat expansion

Search more.