| scholarly article | Q13442814 |
| P50 | author | Laurie Glimcher | Q6501587 |
| Vera M Ruda | Q79184785 | ||
| Takao Iwawaki | Q80174205 | ||
| Victor E. Koteliansky | Q96203215 | ||
| Ann-Hwee Lee | Q124214884 | ||
| P2093 | author name string | Andrew H Lichtman | |
| Margarite Tarrio | |||
| Kevin Fitzgerald | |||
| Jae-Seon So | |||
| Kyu Yeon Hur | |||
| Maria Frank-Kamenetsky | |||
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response | Q24305069 | ||
| Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase | Q24316661 | ||
| Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins | Q24601354 | ||
| Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates | Q24646644 | ||
| Molecular biology of PCSK9: its role in LDL metabolism | Q27488922 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
| Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
| Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia | Q28295479 | ||
| Tunicamycin induces ubiquitination and degradation of apolipoprotein B in HepG2 cells | Q28347626 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
| Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure | Q28510354 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| Angptl3 regulates lipid metabolism in mice | Q28586080 | ||
| Cloning of mammalian Ire1 reveals diversity in the ER stress responses | Q28587224 | ||
| XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
| Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
| The mammalian unfolded protein response | Q29547400 | ||
| The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells | Q33320542 | ||
| Lipid-like materials for low-dose, in vivo gene silencing | Q33583399 | ||
| IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level | Q33707431 | ||
| The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. | Q33777806 | ||
| Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice | Q33852162 | ||
| Inflammation and endoplasmic reticulum stress in obesity and diabetes | Q33913657 | ||
| A status report on RNAi therapeutics | Q34013891 | ||
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
| Proatherogenic immune responses are regulated by the PD-1/PD-L pathway in mice. | Q34582934 | ||
| siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids | Q34955791 | ||
| Intersection of the unfolded protein response and hepatic lipid metabolism | Q34985745 | ||
| Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
| Rat carboxylesterase ES-4 enzyme functions as a major hepatic neutral cholesteryl ester hydrolase. | Q35562853 | ||
| Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice | Q35709954 | ||
| IRE1α activation protects mice against acetaminophen-induced hepatotoxicity | Q35760821 | ||
| Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy | Q36254323 | ||
| Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. | Q36377266 | ||
| Mouse models for atherosclerosis and pharmaceutical modifiers. | Q36836487 | ||
| Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. | Q37036119 | ||
| Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
| Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability | Q37377347 | ||
| Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1. | Q37670368 | ||
| Role of endoplasmic reticulum neutral lipid hydrolases | Q37870490 | ||
| Stressed out about obesity: IRE1α-XBP1 in metabolic disorders | Q37894253 | ||
| Endoplasmic reticulum stress, obesity and diabetes | Q37926034 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| Identification of a consensus element recognized and cleaved by IRE1 alpha. | Q38343711 | ||
| Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice | Q38354947 | ||
| IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. | Q39422225 | ||
| XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum | Q39659690 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis | Q41904044 | ||
| Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease | Q44934521 | ||
| Involvement of endoplasmic reticulum stress in insulin resistance and diabetes | Q45127777 | ||
| Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule. | Q53591929 | ||
| Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity | Q82688246 | ||
| P433 | issue | 4 | |
| P921 | main subject | lipid | Q11367 |
| gene silencing | Q1431332 | ||
| P304 | page(s) | 487-499 | |
| P577 | publication date | 2012-10-01 | |
| P1433 | published in | Cell Metabolism | Q1254684 |
| P1476 | title | Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice | |
| P478 | volume | 16 |
| Q91725869 | 24(S)-Hydroxycholesterol induces ER dysfunction-mediated unconventional cell death |
| Q54379648 | A RIDDle solved: why an intact IRE1α/XBP-1 signaling relay is key for humoral immune responses. |
| Q42914308 | A new RIDDle in DC-mediated cross-presentation |
| Q37597070 | Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis |
| Q49850608 | Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE1α signaling |
| Q36596344 | C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver |
| Q39414484 | Carboxylesterases in lipid metabolism: from mouse to human |
| Q90119301 | Cellular adaptation to hypoxia through hypoxia inducible factors and beyond |
| Q38241810 | Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview. |
| Q35626096 | Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress |
| Q91894003 | Contribution of the Unfolded Protein Response (UPR) to the Pathogenesis of Proteasome-Associated Autoinflammatory Syndromes (PRAAS) |
| Q47813504 | Coordinating Organismal Metabolism During Protein Misfolding in the ER Through the Unfolded Protein Response |
| Q92255067 | Coupling of COPII vesicle trafficking to nutrient availability by the IRE1α-XBP1s axis |
| Q50987952 | Cross-Talk Between FSH and Endoplasmic Reticulum Stress: A Mutually Suppressive Relationship. |
| Q91759847 | Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress |
| Q37066974 | Deregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophy in vivo. |
| Q54123115 | Dual role for inositol-requiring enzyme 1α in promoting the development of hepatocellular carcinoma during diet-induced obesity in mice. |
| Q47894399 | ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras. |
| Q42199386 | ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development |
| Q36777229 | ER stress: Autophagy induction, inhibition and selection. |
| Q58756411 | ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes |
| Q45874593 | Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease |
| Q37673642 | Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in Mice |
| Q64057135 | Endoplasmic Reticulum Stress in Metabolic Liver Diseases and Hepatic Fibrosis |
| Q38925531 | Endoplasmic reticulum proteostasis in hepatic steatosis. |
| Q38385700 | Endoplasmic reticulum quality control in cancer: Friend or foe. |
| Q97522970 | Endoplasmic reticulum stress and liver diseases |
| Q40051888 | Endoplasmic reticulum stress and unfolded protein response in infection by intracellular parasites. |
| Q38989169 | Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA. |
| Q38218597 | Endoplasmic reticulum stress response in yeast and humans. |
| Q57243233 | Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications |
| Q26996783 | Energy metabolism in the liver |
| Q53716840 | Exercise, heat shock proteins and insulin resistance. |
| Q28818754 | Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression |
| Q88537974 | Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice |
| Q51324999 | Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARα axis signalling. |
| Q58616116 | Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH |
| Q39048675 | Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice |
| Q36382065 | Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet |
| Q102220441 | Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α |
| Q37282044 | IRE1: ER stress sensor and cell fate executor |
| Q48519557 | IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers. |
| Q64999429 | IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs. |
| Q50129802 | IRE1α siRNA relieves endoplasmic reticulum stress-induced apoptosis and alleviates diabetic peripheral neuropathy in vivo and in vitro |
| Q35868391 | IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis |
| Q57285558 | IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity |
| Q47104419 | Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice |
| Q26827218 | Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway |
| Q49884225 | Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs |
| Q37597073 | Insulin regulates the unfolded protein response in human adipose tissue. |
| Q34077404 | Insulin resistance is associated with diminished endoplasmic reticulum stress responses in adipose tissue of healthy and diabetic subjects |
| Q36607027 | Integration of Downstream Signals of Insulin-like Growth Factor-1 Receptor by Endoplasmic Reticulum Stress for Estrogen-Induced Growth or Apoptosis in Breast Cancer Cells |
| Q27015015 | Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases |
| Q36063732 | Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status |
| Q34380313 | Lack of XBP-1 impedes murine cytomegalovirus gene expression. |
| Q64067098 | Leaf Extract Reverts Hypertriglyceridemia via Downregulation of the Hepatic XBP-1s/PDI/MTP Axis in Monosodium L-Glutamate-Induced Obese Rats |
| Q60909527 | Linking Endoplasmic Reticular Stress and Alternative Splicing |
| Q34107296 | Lipase maturation factor 1 (lmf1) is induced by endoplasmic reticulum stress through activating transcription factor 6α (Atf6α) signaling. |
| Q49843619 | Liver function and dysfunction - a unique window into the physiological reach of ER stress and the unfolded protein response |
| Q55288034 | Liver transcriptome analysis reveals extensive transcriptional plasticity during acclimation to low salinity in Cynoglossus semilaevis. |
| Q37286045 | Liver-specific cholesteryl ester hydrolase deficiency attenuates sterol elimination in the feces and increases atherosclerosis in ldlr-/- mice |
| Q37665470 | Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr-/- mice |
| Q38748145 | Metabolic Control of Plasma Cell Differentiation- What We Know and What We Don't Know |
| Q36286532 | MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivo |
| Q90484369 | MicroRNAs: Unfolding the Link Between Inositol-Requiring Enzyme 1α and Fatty Liver |
| Q38076705 | Minireview: endoplasmic reticulum stress: control in protein, lipid, and signal homeostasis. |
| Q92538749 | Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain |
| Q28393599 | Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment |
| Q33755566 | Molecular mechanisms and new treatment strategies for non-alcoholic steatohepatitis (NASH) |
| Q38467774 | Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death |
| Q36540356 | Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. |
| Q36379500 | PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response. |
| Q97636448 | Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming |
| Q54122859 | Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization. |
| Q38209331 | Physiological roles of regulated Ire1 dependent decay |
| Q38704807 | Protein misfolding in the endoplasmic reticulum as a conduit to human disease |
| Q57294850 | RNA Splicing in the Transition from B Cells to Antibody-Secreting Cells: The Influences of ELL2, Small Nuclear RNA, and Endoplasmic Reticulum Stress |
| Q45387412 | Regulated IRE1-dependent decay participates in curtailing immunoglobulin secretion from plasma cells |
| Q34995137 | Regulation of sumo mRNA during endoplasmic reticulum stress |
| Q37352508 | Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences. |
| Q54397189 | Role of the unfolded protein response in organ physiology: lessons from mouse models. |
| Q37463911 | SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease |
| Q41876369 | Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells |
| Q38202500 | Signaling pathways from the endoplasmic reticulum and their roles in disease |
| Q34002255 | Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition |
| Q27640568 | Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors |
| Q27681927 | Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response |
| Q37512024 | Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α |
| Q48708732 | Systemic effects of AGEs in ER stress induction in vivo |
| Q37682288 | Targeting IRE1 with small molecules counteracts progression of atherosclerosis |
| Q38074493 | Targeting endoplasmic reticulum stress in metabolic disease |
| Q38489729 | Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases |
| Q38132652 | Targeting the unfolded protein response in disease. |
| Q42970598 | Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network |
| Q52583601 | The Role of IRE1 Signaling in Central Nervous System Diseases. |
| Q37583530 | The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis |
| Q38825911 | The role of ER stress in lipid metabolism and lipotoxicity |
| Q93350086 | The role of X-box binding protein 1 in the hepatic response to refeeding in mice |
| Q61455138 | The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1 |
| Q36866561 | The unfolded protein response and gastrointestinal disease |
| Q38162132 | The unfolded protein response in fatty liver disease |
| Q38784676 | The unfolded protein response in skeletal development and homeostasis |
| Q33569654 | Thyroid dysfunction associated with follicular cell steatosis in obese male mice and humans |
| Q89944336 | Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers |
| Q91809029 | Understanding the Role of the Unfolded Protein Response Sensor IRE1 in the Biology of Antigen Presenting Cells |
| Q41997586 | Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish |
| Q92795478 | Unravel the molecular mechanism of XBP1 in regulating the biology of cancer cells |
| Q104073438 | XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis |
| Q90257841 | [Effects of sera of rats fed with Huganqingzhi tablets on endoplasmic reticulum stress in a HepG2 cell model of nonalcoholic fatty liver disease] |
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