scholarly article | Q13442814 |
P2093 | author name string | Harmeet Malhi | |
Jessica L Maiers | |||
P2860 | cites work | Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors | Q22008465 |
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells | Q37388595 | ||
The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy | Q37519318 | ||
Role of Protein Quality Control Failure in Alcoholic Hepatitis Pathogenesis | Q37729414 | ||
The role of MAPK signalling pathways in the response to endoplasmic reticulum stress | Q38179717 | ||
Kupffer cells: increasingly significant role in nonalcoholic fatty liver disease | Q38242840 | ||
XBP1s Is an Anti-lipogenic Protein | Q38291938 | ||
METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction. | Q38297313 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response | Q38326929 | ||
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice | Q38354947 | ||
Lysophosphatidylcholine and lysophosphatidylinosiol--novel promissing signaling molecules and their possible therapeutic activity | Q38368661 | ||
4μ8C Inhibits Insulin Secretion Independent of IRE1α RNase Activity | Q38742646 | ||
Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway. | Q38772620 | ||
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Q38845249 | ||
Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways | Q38981604 | ||
Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis | Q39049164 | ||
CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis | Q39709114 | ||
C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis. | Q39726227 | ||
Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis | Q39731721 | ||
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes | Q40064603 | ||
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells | Q40313352 | ||
Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2. | Q40966919 | ||
Physiological/pathological ramifications of transcription factors in the unfolded protein response | Q41583320 | ||
Increased synthesis of secreted proteins induces expression of glucose-regulated proteins in butyrate-treated Chinese hamster ovary cells | Q41758613 | ||
Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing. | Q41811106 | ||
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice | Q41825121 | ||
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis | Q41904044 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development | Q42199386 | ||
Autophagy mediated by endoplasmic reticulum stress enhances the caffeine-induced apoptosis of hepatic stellate cells | Q42280211 | ||
ER Stress-induced Inflammasome Activation Contributes to Hepatic Inflammation and Steatosis | Q42355577 | ||
Synthesis of all plasma protein fractions except gamma globulins by the liver; the use of zone electrophoresis and lysine-epsilon-C14 to define the plasma proteins synthesized by the isolated perfused liver | Q42926854 | ||
Pioglitazone reduces ER stress in the liver: direct monitoring of in vivo ER stress using ER stress-activated indicator transgenic mice. | Q43269505 | ||
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease | Q44934521 | ||
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. | Q45345766 | ||
An unfolded protein-induced conformational switch activates mammalian IRE1. | Q46020686 | ||
Current and Future Therapeutic Regimens for Non-alcoholic Fatty Liver Disease (NAFLD) and Non-alcoholic Steatohepatitis (NASH). | Q46057830 | ||
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice. | Q46228637 | ||
Fatty acid cycling in human hepatoma cells and the effects of troglitazone | Q46508430 | ||
The effect of oleic and palmitic acid on induction of steatosis and cytotoxicity on rat hepatocytes in primary culture | Q46623219 | ||
Acyl chain-dependent effect of lysophosphatidylcholine on human neutrophils | Q46989306 | ||
In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stress | Q47230349 | ||
Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum | Q47388417 | ||
Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. | Q47863231 | ||
The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity | Q48043703 | ||
The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization | Q49545301 | ||
Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE1α signaling | Q49850608 | ||
The synthesis rates of total liver protein and plasma albumin determined simultaneously in vivo in humans | Q50161065 | ||
Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins | Q50336381 | ||
Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis. | Q50485855 | ||
The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice. | Q51224682 | ||
Quercetin stimulates mitochondrial apoptosis dependent on activation of endoplasmic reticulum stress in hepatic stellate cells. | Q51544437 | ||
Attenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency. | Q51767284 | ||
Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress. | Q52582464 | ||
Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation. | Q52657397 | ||
Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance. | Q53181684 | ||
Endoplasmic reticulum stress of Kupffer cells involved in the conversion of natural regulatory T cells to Th17 cells in liver ischemia-reperfusion injury. | Q53336916 | ||
Ischemia-reperfusion injury of the liver with special reference to calcium-dependent mechanisms | Q34548138 | ||
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
The RtcB RNA ligase is an essential component of the metazoan unfolded protein response | Q34691382 | ||
The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells | Q34807567 | ||
Triglyceride accumulation protects against fatty acid-induced lipotoxicity | Q34866329 | ||
Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy | Q35152201 | ||
Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein | Q35330939 | ||
Death receptor 5 signaling promotes hepatocyte lipoapoptosis | Q35604362 | ||
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway | Q35723848 | ||
Hepatocyte transplantation into diseased mouse liver. Kinetics of parenchymal repopulation and identification of the proliferative capacity of tetraploid and octaploid hepatocytes | Q35829671 | ||
Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin | Q35930512 | ||
Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis | Q35939383 | ||
Structural Insights into IRE1 Functions in the Unfolded Protein Response | Q36148938 | ||
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents | Q36183590 | ||
A quantitative stereological description of the ultrastructure of normal rat liver parenchymal cells | Q36189494 | ||
ER stress induces NLRP3 inflammasome activation and hepatocyte death. | Q36293033 | ||
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response | Q36322641 | ||
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection | Q36365792 | ||
Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet | Q36382065 | ||
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis | Q36600595 | ||
Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains | Q36712468 | ||
The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes | Q36861041 | ||
Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy | Q36941185 | ||
C/EBP homologous protein-induced macrophage apoptosis protects mice from steatohepatitis | Q36967242 | ||
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Q37091581 | ||
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss | Q37105351 | ||
Liver Injury and the Activation of the Hepatic Myofibroblasts | Q37109402 | ||
ATF4 protein deficiency protects against high fructose-induced hypertriglyceridemia in mice. | Q37132127 | ||
ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading. | Q37188851 | ||
ATF6 modulates SREBP2-mediated lipogenesis. | Q37260315 | ||
Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress | Q37294234 | ||
Membrane phospholipid synthesis and endoplasmic reticulum function | Q37308781 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress | Q58545168 | ||
IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs. | Q64999429 | ||
Betaine effects on hepatic methionine metabolism elicited by short-term ethanol feeding | Q71721014 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis | Q81441036 | ||
ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosis | Q84283864 | ||
Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis | Q89115325 | ||
IRE1α aggravates ischemia reperfusion injury of fatty liver by regulating phenotypic transformation of kupffer cells | Q89406106 | ||
Alcoholic liver disease | Q90988810 | ||
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate | Q91004301 | ||
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 | ||
Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response | Q24292966 | ||
A synthetic biology approach identifies the mammalian UPR RNA ligase RtcB | Q24301555 | ||
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation | Q24302539 | ||
Palmitoylated calnexin is a key component of the ribosome-translocon complex | Q24304833 | ||
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway | Q24537844 | ||
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis | Q24554008 | ||
Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis | Q27333658 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network | Q27933904 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response | Q28589998 | ||
Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly | Q28624200 | ||
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress | Q29615495 | ||
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner | Q30701525 | ||
A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice | Q33604576 | ||
Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study | Q33814559 | ||
Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death | Q33840334 | ||
Regulation of basal cellular physiology by the homeostatic unfolded protein response | Q33886820 | ||
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. | Q33960826 | ||
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity | Q34181503 | ||
Extensive translatome remodeling during ER stress response in mammalian cells | Q34264546 | ||
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding | Q34524224 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 235-248 | |
P577 | publication date | 2019-05-01 | |
P1433 | published in | Seminars in Liver Disease | Q15724477 |
P1476 | title | Endoplasmic Reticulum Stress in Metabolic Liver Diseases and Hepatic Fibrosis | |
P478 | volume | 39 |
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