XBP1s Is an Anti-lipogenic Protein

scientific article

XBP1s Is an Anti-lipogenic Protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M116.728949
P932PMC publication ID5016136
P698PubMed publication ID27325692

P50authorGerald I. ShulmanQ52509909
Dongyan ZhangQ96683972
P2093author name stringJustin Lee
Umut Ozcan
Yingjiang Zhou
Mario Andres Salazar Hernandez
Hilde Herrema
P2860cites workCurrent efforts and trends in the treatment of NASHQ28261339
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Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocationQ28510062
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Autophagy regulates lipid metabolismQ29547421
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Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
BRD7 regulates XBP1s' activity and glucose homeostasis through its interaction with the regulatory subunits of PI3KQ33838482
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.Q33896647
GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagyQ34034795
Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalenceQ34321390
Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2Q34804981
Cellular mechanism of insulin resistance in nonalcoholic fatty liver diseaseQ35239565
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasisQ35419603
Human fatty liver disease: old questions and new insightsQ35588477
Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out miceQ35709954
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetesQ35811523
The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolismQ36497151
Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adultsQ36566370
CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistanceQ36583167
Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjectsQ36588248
Endoplasmic reticulum stress sensing in the unfolded protein responseQ36626672
Spectrum of liver disease in type 2 diabetes and management of patients with diabetes and liver diseaseQ36747007
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight lossQ37105351
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1aQ37360326
Unfolded protein response signaling and metabolic diseasesQ37488392
Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic diseaseQ38250379
Tackling of unhealthy diets, physical inactivity, and obesity: health effects and cost-effectivenessQ39817685
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
P4510describes a project that usesImageJQ1659584
P433issue33
P407language of work or nameEnglishQ1860
P304page(s)17394-17404
P577publication date2016-06-20
P1433published inJournal of Biological ChemistryQ867727
P1476titleXBP1s Is an Anti-lipogenic Protein
P478volume291

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cites work (P2860)
Q49884136Cyclophilin D Deficiency Attenuates Mitochondrial Perturbation and Ameliorates Hepatic Steatosis.
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