Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing.

scientific article published on 25 May 2016

Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15252/EMMM.201505925
P932PMC publication ID4931288
P698PubMed publication ID27226027

P50authorKrista RomboutsQ39605190
Joey LauQ80959878
Johan KreugerQ89288413
Pär GerwinsQ89288415
Femke HeindryckxQ100996447
P2093author name stringMarkella Ponticos
François Binet
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MicroRNAs inhibit the translation of target mRNAs on the endoplasmic reticulum in ArabidopsisQ33355753
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Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease?Q34058302
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Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1.Q34650822
Endoplasmic reticulum stress implicated in the development of renal fibrosisQ35882857
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Pathologic Regulation of Collagen I by an Aberrant Protein Phosphatase 2A/Histone Deacetylase C4/MicroRNA-29 Signal Axis in Idiopathic Pulmonary Fibrosis FibroblastsQ36049259
Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver DiseaseQ36102239
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IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.Q37091581
The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in miceQ37115015
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Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lungQ37370914
SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver diseaseQ37463911
Endoplasmic reticulum stress contributes to aortic stiffening via proapoptotic and fibrotic signaling mechanismsQ37731726
Fibroblasts and myofibroblasts: what are we talking about?Q37836316
MicroRNAs, transforming growth factor beta-1, and tissue fibrosis.Q38050081
Stressed to death - mechanisms of ER stress-induced cell death.Q38134017
Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease.Q38134341
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.Q38311676
Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts.Q38471220
Seven steps to stellate cellsQ38759262
A decrease in miR-150 regulates the malignancy of pancreatic cancer by targeting c-Myb and MUC4.Q38927350
Activation of hepatic stellate cells is suppressed by microRNA-150.Q39162909
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.Q39299575
c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic developmentQ39955779
Endoplasmic reticulum stress as a pro-fibrotic stimulusQ40282765
Transformation-associated gene regulation by ATF6alpha during hepatocarcinogenesisQ40338640
Failed degradation of JunB contributes to overproduction of type I collagen and development of dermal fibrosis in patients with systemic sclerosisQ42077845
TGF-beta1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesisQ42470383
miR-150 down-regulation contributes to the constitutive type I collagen overexpression in scleroderma dermal fibroblasts via the induction of integrin β3.Q45712471
Comparison of three research models of portal hypertension in mice: macroscopic, histological and portal pressure evaluationQ46420455
Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1.Q48134071
Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic miceQ49064298
MARCKS actin-binding capacity mediates actin filament assembly during mitosis in human hepatic stellate cells.Q53171098
Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye DiseaseQ57983635
Hepatic expression of c-Myb in chronic human liver diseaseQ73939852
Quantification of histochemical staining by color deconvolutionQ74448733
ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulumQ80935578
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-IIQ81144490
P4510describes a project that usesImageJQ1659584
P433issue7
P921main subjectendoplasmic reticulumQ79927
P304page(s)729-744
P577publication date2016-07-01
P1433published inEMBO Molecular MedicineQ15817279
P1476titleEndoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing
P478volume8

Reverse relations

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