ER stress induces NLRP3 inflammasome activation and hepatocyte death.

scientific article

ER stress induces NLRP3 inflammasome activation and hepatocyte death. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/CDDIS.2015.248
P932PMC publication ID4650444
P698PubMed publication ID26355342
P5875ResearchGate publication ID281682981

P50authorRodolphe AntyQ56587840
Jean GugenheimQ56587846
Stéphanie PatourauxQ57080158
Carole RovereQ57080162
Cynthia LebeaupinQ59676716
Philippe GualQ43082600
Antonio IannelliQ48030177
Béatrice Bailly-MaitreQ37376962
Vanessa LavallardQ37382537
P2093author name stringG Adam
A Tran
D Rousseau
M C Saint-Paul
E Proics
A S Schneck
S Bonnafous
C H D de Bieville
O Le Thuc
P2860cites workAttenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency.Q51767284
Hepatocyte Apoptosis, Expression of Death Receptors, and Activation of NF-κB in the Liver of Nonalcoholic and Alcoholic Steatohepatitis PatientsQ57760193
TrueQ60877360
Pattern of progression in liver injury following jejunoileal bypass for morbid obesityQ69479817
Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.Q37726154
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.Q38268983
Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8.Q38339644
NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice.Q39164863
Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasomeQ39299566
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.Q39299575
CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosisQ39709114
Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis modelQ39850608
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC developmentQ42199386
Dexamethasone inhibits spontaneous apoptosis in primary cultures of human and rat hepatocytes via Bcl-2 and Bcl-xL inductionQ43586550
Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgeryQ43637450
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver diseaseQ44934521
Involvement of endoplasmic reticulum stress in insulin resistance and diabetesQ45127777
Pathology of nonalcoholic steatohepatitisQ46743666
Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53Q24300781
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1Q24302166
Roles of CHOP/GADD153 in endoplasmic reticulum stressQ24302185
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alphaQ24322072
Endoplasmic reticulum stress: cell life and death decisions.Q24536108
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesityQ28512778
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox stateQ28572472
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Metabolic endotoxemia initiates obesity and insulin resistanceQ29547720
Steatohepatitis: a tale of two "hits"?Q29547771
Design and validation of a histological scoring system for nonalcoholic fatty liver diseaseQ29614930
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistanceQ29616026
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012Q29616161
TLR4 links innate immunity and fatty acid-induced insulin resistanceQ29617577
Nonalcoholic fatty liver diseaseQ29619354
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.Q30408769
The inflammasomes.Q33521252
Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intoleranceQ33673551
Osteopontin deficiency aggravates hepatic injury induced by ischemia-reperfusion in miceQ33720224
Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expressionQ34199861
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injuryQ34479417
Lipopolysaccharide-binding protein plasma levels and liver TNF-alpha gene expression in obese patients: evidence for the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitisQ34713484
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.Q35041384
Inflammasome is a central player in the induction of obesity and insulin resistanceQ35216914
Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitisQ36050135
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivityQ36931760
C/EBP homologous protein-induced macrophage apoptosis protects mice from steatohepatitisQ36967242
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight lossQ37105351
Inflammasomes: guardians of cytosolic sanctityQ37361455
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P921main subjectinflammasome complexQ412405
P304page(s)e1879
P577publication date2015-09-10
P1433published inCell Death and DiseaseQ2197222
P1476titleER stress induces NLRP3 inflammasome activation and hepatocyte death
P478volume6

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