Exercise, heat shock proteins and insulin resistance.

scientific article

Exercise, heat shock proteins and insulin resistance. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1098/RSTB.2016.0529
P932PMC publication ID5717529
P698PubMed publication ID29203714

P50authorAlex T Von SchulzeQ59681333
Paige C GeigerQ89479081
P2093author name stringAshley E Archer
P2860cites workHSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interactionQ21145793
Resistance training increases heat shock protein levels in skeletal muscle of young and old ratsQ23924233
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunctionQ24632414
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1Q24679555
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesisQ27860471
Inflammation and metabolic disordersQ27860923
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1Q28131760
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IkkbetaQ28188643
Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetesQ28251174
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractionsQ28576573
Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed ratsQ28581524
Exercise training and experimental diabetes modulate heat shock protein response in brainQ28583889
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscleQ43990155
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.Q44240302
Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and releaseQ44394452
Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesityQ44563999
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetesQ29614548
The unfolded protein response: controlling cell fate decisions under ER stress and beyondQ29615499
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulatorsQ29618401
A central role for JNK in obesity and insulin resistanceQ29619778
Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic programQ30426645
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington diseaseQ30474580
cDNA Cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised ratsQ30656428
Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signalingQ30856517
In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformationQ33583065
The transcriptional coactivator PGC1α protects against hyperthermic stress via cooperation with the heat shock factor HSF1.Q33586827
Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistanceQ33646728
Glucose ingestion attenuates the exercise-induced increase in circulating heat shock protein 72 and heat shock protein 60 in humansQ33716811
Exercise induces the release of heat shock protein 72 from the human brain in vivoQ33716849
Activation of the heat shock transcription factor by hypoxia in mammalian cellsQ33746641
CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) miceQ33943164
The PPARα-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathwayQ34143232
Effect of the volume and intensity of exercise training on insulin sensitivityQ34230270
Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinaseQ34271504
Clinical implications of thermal therapy in lifestyle-related diseases.Q34275863
Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarctionQ34353028
Acute heat treatment improves insulin-stimulated glucose uptake in aged skeletal muscleQ34598478
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complexQ34673344
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistanceQ34708975
The chaperone balance hypothesis: the importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical managementQ35169987
Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemiaQ35602950
Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal levelQ35616052
JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failureQ35783613
Inducing Muscle Heat Shock Protein 70 Improves Insulin Sensitivity and Muscular Performance in Aged MiceQ35784862
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetesQ35837720
Divergence of intracellular and extracellular HSP72 in type 2 diabetes: does fat matter?Q35854610
Identification of matrine as a promising novel drug for hepatic steatosis and glucose intolerance with HSP72 as an upstream targetQ36016417
Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistanceQ36222221
Genetics of aerobic and anaerobic performances.Q36292345
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.Q36330343
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanismQ44564039
Vitamin E isoform-specific inhibition of the exercise-induced heat shock protein 72 expression in humansQ44834214
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver diseaseQ44934521
Hsp70 release from peripheral blood mononuclear cells.Q45098360
Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue-specific fashionQ45182784
Influence of exercise on NA- and Hsp72-induced release of IFNγ by the peritoneal suspension of macrophages and lymphocytes from genetically obese Zucker rats.Q45365434
The repeated bout effect and heat shock proteins: intramuscular HSP27 and HSP70 expression following two bouts of eccentric exercise in humansQ45711233
Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injuryQ46112159
Inducible isoform of HSP70 is constitutively expressed in a muscle fiber type specific patternQ46116553
Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trialQ47234529
Exercise training modulates heat shock protein response in diabetic ratsQ47788938
Aerobic capacity mediates susceptibility for the transition from steatosis to steatohepatitisQ47886086
Waon Therapy for Managing Chronic Heart Failure - Results From a Multicenter Prospective Randomized WAON-CHF StudyQ48820102
The effects of repeated thermal therapy on quality of life in patients with type II diabetes mellitusQ49160062
Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis.Q50938481
Mycobacterium tuberculosis- induced neutrophil extracellular traps activate human macrophages.Q51026879
Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP.Q51584140
Dysregulation of muscle lipid metabolism in rats selectively bred for low aerobic running capacity.Q52576851
Trained men display increased basal heat shock protein content of skeletal muscle.Q52587689
Obesity depresses the anti-inflammatory HSP70 pathway, contributing to NAFLD progression.Q53013442
Chia (Salvia hispanica L.) enhances HSP, PGC-1α expressions and improves glucose tolerance in diet-induced obese rats.Q53273182
Oral supplementations with L-glutamine or L-alanyl-L-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance.Q53810787
HSP72 as a complementary protection against oxidative stress induced by exercise in the soleus muscle of rats.Q54032435
Repeated high-force eccentric exercise: effects on muscle pain and damage.Q54398932
Role of extracellular HSP72 in acute stress-induced potentiation of innate immunity in active rats.Q54536327
Exercise induces hepatosplanchnic release of heat shock protein 72 in humansQ59326285
Absolute amounts and diffusibility of HSP72, HSP25, and αB-crystallin in fast- and slow-twitch skeletal muscle fibers of ratQ61427797
Adaptation to exercise-induced muscle damageQ69420685
Similar dose response of heat shock protein synthesis and intracellular pH change in yeastQ69904222
Splanchnic and peripheral disposal of oral glucose in manQ71763755
HSP70 induction during exercise and heat stress in rats: role of internal temperatureQ72492783
Hot-tub therapy for type 2 diabetes mellitusQ73023044
Muscle fibre stress in response to exercise: synthesis, accumulation and isoform transitions of 70-kDa heat-shock proteinsQ73068032
Previous hyperthermic treatment increases mitochondria oxidative enzyme activity and exercise capacity in ratsQ73286491
HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokineQ73606601
Human skeletal muscle HSP70 response to physical training depends on exercise intensityQ74196108
Exercise-induced elevation of HSP70 is intensity dependentQ74499881
Different skeletal muscle HSP70 responses to high-intensity strength training and low-intensity endurance trainingQ79243441
Artificial selection for high-capacity endurance running is protective against high-fat diet-induced insulin resistanceQ79886735
Effect of training and detraining on the expression of heat shock proteins in m. triceps brachii of untrained males and femalesQ80149735
CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitisQ80229577
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosisQ81441036
Divergent selection for aerobic capacity in rats as a model for complex diseaseQ84370922
Daily heat stress treatment rescues denervation-activated mitochondrial clearance and atrophy in skeletal muscleQ87164788
HSP72 protects against obesity-induced insulin resistanceQ36446531
Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis.Q36497621
Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylationQ36567657
Heat shock protein 72: release and biological significance during exercise.Q36992110
Effects of heated hydrotherapy on muscle HSP70 and glucose metabolism in old and young vervet monkeysQ37004619
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight lossQ37105351
Differential response of heat shock proteins to uphill and downhill exercise in heart, skeletal muscle, lung and kidney tissuesQ37169410
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammationQ37330051
Exercise reduces cellular stress related to skeletal muscle insulin resistanceQ37601126
HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscleQ37715573
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injuryQ38291198
Preheating accelerates mitogen-activated protein (MAP) kinase inactivation post-heat shock via a heat shock protein 70-mediated increase in phosphorylated MAP kinase phosphatase-1.Q38331326
HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress.Q38393668
Heat shock proteins and exercise adaptations. Our knowledge thus far and the road still aheadQ38672562
Cytosolic proteostasis through importing of misfolded proteins into mitochondriaQ38714671
Glucose regulates heat shock factor 1 transcription activity via mTOR pathway in HCC cell linesQ38870931
Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicityQ38911401
Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded viewQ38923148
Obese type 2 diabetics have a blunted hypotensive response to acute hyperthermia therapy that does not affect the perception of thermal stress or physiological strain compared to healthy adults.Q39445117
Oleate blocks palmitate-induced abnormal lipid distribution, endoplasmic reticulum expansion and stress, and insulin resistance in skeletal muscleQ39556161
The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesisQ39700372
Passive heat therapy improves endothelial function, arterial stiffness and blood pressure in sedentary humans.Q39704359
An acute bout of whole body passive hyperthermia increases plasma leptin, but does not alter glucose or insulin responses in obese type 2 diabetics and healthy adults.Q39708135
Different effect of glutamine on macrophage tumor necrosis factor-alpha release and heat shock protein 72 expression in vitro and in vivoQ39885616
JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell deathQ40138480
Modeling type 2 diabetes-like hyperglycemia in C. elegans on a microdeviceQ40220341
JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cellsQ40278269
Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteinsQ40436107
Effects of heat stress and mechanical stretch on protein expression in cultured skeletal muscle cellsQ40627735
c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascadeQ40692121
Characterization of a receptor for heat shock protein 70 on macrophages and monocytesQ40824757
The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones.Q40839196
Sounding the alarm: protein kinase cascades activated by stress and inflammationQ41106742
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle.Q42447512
Mild heat stress induces mitochondrial biogenesis in C2C12 myotubes.Q42621761
Deficiency in the Heat Stress Response Could Underlie Susceptibility to Metabolic DiseaseQ42718222
An acylic polyisoprenoid derivative, geranylgeranylacetone protects against visceral adiposity and insulin resistance in high-fat-fed mice.Q42934822
The relationship between heat shock protein 72 expression in skeletal muscle and insulin sensitivity is dependent on adiposity.Q43143948
Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat dietQ43177148
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulinQ43566795
Suppression of tumor necrosis factor-alpha production and neutrophil infiltration during ischemia-reperfusion injury of the liver after heat shock preconditioningQ43787167
Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistanceQ43935456
P433issue1738
P407language of work or nameEnglishQ1860
P921main subjectinsulin resistanceQ1053470
P577publication date2018-01-01
P1433published inPhilosophical Transactions of the Royal Society BQ2153239
P1476titleExercise, heat shock proteins and insulin resistance
P478volume373

Reverse relations

cites work (P2860)
Q60931008Acquired Resilience: An Evolved System of Tissue Protection in Mammals
Q90247545Chaperone-Based Therapeutic Target Innovation: Heat Shock Protein 70 (HSP70) for Type 2 Diabetes Mellitus
Q52761284Heat shock proteins as modulators and therapeutic targets of chronic disease: an integrated perspective.
Q64063455Passive heating and glycaemic control in non-diabetic and diabetic individuals: A systematic review and meta-analysis
Q92670282The Sleep-Immune Crosstalk in Health and Disease
Q57820855The effects of coenzyme Q10 on oxidative stress and heat shock proteins in rats subjected to acute and chronic exercise
Q52689970Turning Up the Heat: An Evaluation of the Evidence for Heating to Promote Exercise Recovery, Muscle Rehabilitation and Adaptation.
Q90093988lncRNA-mRNA competing endogenous RNA network in IR-hepG2 cells ameliorated by APBBR decreasing ROS levels: a systematic analysis

Search more.