scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.JCMGH.2016.11.006 |
P8608 | Fatcat ID | release_ivdfe5en4vcrlgw3us2u7zjhay |
P932 | PMC publication ID | 5331781 |
P698 | PubMed publication ID | 28275692 |
P2093 | author name string | Richard M Green | |
Shantel Olivares | |||
Anne S Henkel | |||
Brian LeCuyer | |||
P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors | Q24290397 | ||
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response | Q24305069 | ||
Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response | Q24316572 | ||
Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression | Q24336351 | ||
The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter | Q24531357 | ||
Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter | Q24534978 | ||
Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway | Q24537844 | ||
ER stress controls iron metabolism through induction of hepcidin | Q24630714 | ||
Bile acid transporters | Q24652624 | ||
Bile acids: regulation of synthesis | Q24658139 | ||
The enzymes, regulation, and genetics of bile acid synthesis | Q28204726 | ||
Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP | Q28208653 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine | Q28242281 | ||
Cytochrome P450s and cholesterol homeostasis | Q28254484 | ||
Endoplasmic reticulum stress activates the hepatic activator protein 1 complex via mitogen activated protein kinase-dependent signaling pathways | Q28391490 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver | Q28571688 | ||
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat | Q28577847 | ||
Obstructive cholestasis induces TNF-alpha- and IL-1 -mediated periportal downregulation of Bsep and zonal regulation of Ntcp, Oatp1a4, and Oatp1b2 | Q28579409 | ||
IRE1 signaling affects cell fate during the unfolded protein response | Q29615502 | ||
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability | Q30665173 | ||
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis | Q33553744 | ||
Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia. | Q44138937 | ||
Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis | Q44626804 | ||
Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat. | Q45108263 | ||
Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver | Q46463048 | ||
FGF19 (fibroblast growth factor 19) as a novel target gene for activating transcription factor 4 in response to endoplasmic reticulum stress | Q46735156 | ||
CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury | Q46823993 | ||
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. | Q52541251 | ||
Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers. | Q53543252 | ||
Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents | Q71235032 | ||
Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription | Q73643139 | ||
Interleukin-6 regulates hepatic transporters during acute-phase response | Q80457063 | ||
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis | Q81441036 | ||
Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis | Q33566678 | ||
Contribution of cholesterol 7alpha-hydroxylase to the regulation of lipoprotein metabolism | Q33730842 | ||
Inflammation-induced cholestasis | Q33756581 | ||
A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice | Q34503382 | ||
Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells | Q34550486 | ||
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress | Q34801719 | ||
Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells | Q34894300 | ||
Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes | Q35013686 | ||
Death Receptor-Mediated Cell Death and Proinflammatory Signaling in Nonalcoholic Steatohepatitis | Q35122049 | ||
Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure | Q35128295 | ||
IRE1α activation protects mice against acetaminophen-induced hepatotoxicity | Q35760821 | ||
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. | Q35763029 | ||
Dysregulated intrahepatic CD4(+) T-cell activation drives liver inflammation in ileitis-prone SAMP1/YitFc mice | Q35880725 | ||
Endoplasmic reticulum stress in liver disease | Q36031838 | ||
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
Hepatic Xbp1 Gene Deletion Promotes Endoplasmic Reticulum Stress-induced Liver Injury and Apoptosis | Q36444262 | ||
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis | Q36600595 | ||
Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration | Q36732805 | ||
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Q37091581 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Role of bile acids and bile acid receptors in metabolic regulation | Q37363616 | ||
Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter | Q37375465 | ||
Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors | Q37381843 | ||
Getting RIDD of RNA: IRE1 in cell fate regulation | Q38198370 | ||
Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice | Q38289975 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice | Q38354947 | ||
Effects of triglyceride on ER stress and insulin resistance | Q40080488 | ||
Bile Salt Binding to Serum Components. Taurocholate Incorporation into High-Density Lipoprotein Revealed by Photoaffinity Labelling | Q40280260 | ||
Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene. | Q40490287 | ||
Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate | Q40931435 | ||
Hepatocyte nuclear factor 1 binds to and transactivates the human but not the rat CYP7A1 promoter | Q41678786 | ||
Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice | Q42110387 | ||
Endotoxin, TNF, and IL-1 decrease cholesterol 7 alpha-hydroxylase mRNA levels and activity | Q42529069 | ||
Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway | Q43559873 | ||
Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver | Q43563069 | ||
The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by | Q43636951 | ||
Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet | Q44119079 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 2 | |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 261-271 | |
P577 | publication date | 2016-12-10 | |
P1433 | published in | Cellular and molecular gastroenterology and hepatology | Q27726289 |
P1476 | title | Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in Mice | |
P478 | volume | 3 |
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Q55344969 | Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid-Induced Injury. |
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