Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers.

scientific article

Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/LABINVEST.3700603
P698PubMed publication ID17607300
P5875ResearchGate publication ID6230970

P50authorRavi R. JhaveriQ45422146
P2093author name stringLiu Yang
Anna Mae Diehl
Jiawen Huang
Yi Qi
P2860cites workTwo classes of CD1 genesQ24293259
Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1cQ24324512
Murine CD1d-restricted T cell recognition of cellular lipidsQ40894441
Mouse CD1 is distinct from and co-exists with TL in the same thymusQ41092898
Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells.Q41411454
The influence of CD1d in postselection NKT cell maturation and homeostasisQ42483693
Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the targetQ42942508
Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramerQ46482007
Size of the population of CD4+ natural killer T cells in the liver is maintained without supply by the thymus during adult lifeQ47199809
CD1d function is regulated by microsomal triglyceride transfer proteinQ47703480
NKT cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine NKT cellsQ47710143
The rabbit CD1 and the evolutionary conservation of the CD1 gene familyQ48308062
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infectionsQ50092191
NF-kappaB activation in Kupffer cells after partial hepatectomy.Q50767519
Interplay of cytokines and microbial signals in regulation of CD1d expression and NKT cell activation.Q53658171
Natural T cells in the human liver: cytotoxic lymphocytes with dual T cell and natural killer cell phenotype and function are phenotypically heterogenous and include Vα24-JαQ and γδ T cell receptor bearing cellsQ58143624
CD1d-Restricted NKT Cells: An Interstrain ComparisonQ62230429
NK1.1+ CD4+ CD8- thymocytes with specific lymphokine secretionQ70527039
Discrimination of two subsets of CD1 molecules in the sheepQ71734860
Intensive generation of NK1.1- extrathymic T cells in the liver by injection of bone marrow cells isolated from mice with a mutation of polymorphic major histocompatibility complex antigensQ73818977
In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasiaQ73835503
Pathogenesis of autoimmune hepatitisQ78322634
Favored T helper 1 response in a mouse model of hepatosteatosis is associated with enhanced T cell-mediated hepatitisQ79788192
A thymic precursor to the NK T cell lineageQ95783850
Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigensQ24628447
Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoidsQ24806047
Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding grooveQ27740401
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
CD1: antigen presentation and T cell functionQ28251508
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramidesQ28254991
Troglitazone action is independent of adipose tissueQ28379255
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stressQ28506667
NKT cells derive from double-positive thymocytes that are positively selected by CD1dQ28508188
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4Q28594577
The liver as a crucial organ in the first line of host defense: the roles of Kupffer cells, natural killer (NK) cells and NK1.1 Ag+ T cells in T helper 1 immune responsesQ33916569
A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6.Q34165704
Collagen measured in primary cultures of normal rat hepatocytes derives from lipocytes within the monolayerQ34559156
Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatographyQ34722878
Transcriptional and translational control in the Mammalian unfolded protein responseQ34762452
The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansionQ35978664
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cellsQ36096376
A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.Q36228473
Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cellQ36300615
Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramersQ36368804
Presentation of the same glycolipid by different CD1 moleculesQ36370124
A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stageQ36370202
Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer stainingQ36370359
The liver as an immunological organQ36382243
The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognitionQ37484801
NK T cell activation promotes Chlamydia trachomatis infection in vivoQ37864144
Hepatic expression of microsomal triglyceride transfer protein and in vivo secretion of triglyceride-rich lipoproteins are increased in obese diabetic miceQ38290816
Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damageQ38314701
Adoptive transfer of regulatory NKT lymphocytes ameliorates non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice and is associated with intrahepatic CD8 trappingQ38315752
Amelioration of non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice by oral immune regulation towards liver-extracted proteins is associated with elevated intrahepatic NKT lymphocytes and serum IL-10 levelsQ38319270
Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver diseaseQ38320784
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed miceQ38354947
P433issue9
P921main subjectendoplasmic reticulumQ79927
P304page(s)927-937
P577publication date2007-07-02
P1433published inLaboratory InvestigationQ6467260
P1476titleEndoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers.
P478volume87

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cites work (P2860)
Q42824021A protective role for CD154 in hepatic steatosis in mice
Q34060210Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease.
Q35982680Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice
Q37191048Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production.
Q36669223Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis
Q47820461CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation
Q28587279CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver
Q36866122Contribution of lipid-reactive natural killer T cells to obesity-associated inflammation and insulin resistance
Q35122049Death Receptor-Mediated Cell Death and Proinflammatory Signaling in Nonalcoholic Steatohepatitis
Q33902002Dietary fatty acids modulate antigen presentation to hepatic NKT cells in nonalcoholic fatty liver disease.
Q42787200Direct identification of rat iNKT cells reveals remarkable similarities to human iNKT cells and a profound deficiency in LEW rats
Q36800154Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury
Q37411006Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride
Q37673642Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in Mice
Q48312436Endoplasmic Reticulum Stress in Mice Increases Hepatic Expression of Genes Carrying a Premature Termination Codon via a Nutritional Status-Independent GRP78-Dependent Mechanism
Q38557011Endoplasmic reticulum stress and Oxidative stress in the pathogenesis of Non-alcoholic fatty liver disease
Q28279152Endoplasmic reticulum stress and atherosclerosis
Q45200756Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor
Q45955316Fructose-induced steatosis in mice: role of plasminogen activator inhibitor-1, microsomal triglyceride transfer protein and NKT cells.
Q33553744Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis
Q34043282Impact of CD1d deficiency on metabolism.
Q28395856Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice
Q44913257Invariant NKT cells and CD1d(+) cells amass in human omentum and are depleted in patients with cancer and obesity.
Q91198621Key features and homing properties of NK cells in the liver are shaped by activated iNKT cells
Q34025822Lipid antigens in immunity
Q26750478Liver immunology and its role in inflammation and homeostasis
Q37326768Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases
Q33933019Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity
Q37495662Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding
Q52603306NKT cells in liver diseases.
Q64252541Oxidative Stress and Antioxidant Biomarkers in Clinical and Experimental Models of Non-Alcoholic Fatty Liver Disease
Q35747483Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation
Q34028751Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function
Q35061420Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death
Q27487853Recombinant adenoviruses expressing Steatosis-associated Hepatitis C virus genotype 3 Core protein produce intracellular lipid accumulation in cultured and primary hepatocytes
Q37802379Redox Balance in the Pathogenesis of Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities
Q33974369Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells
Q26741191Role of NK, NKT cells and macrophages in liver transplantation
Q41873565Role of NKT Cells in the Pathogenesis of NAFLD.
Q26853645Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease
Q34128069Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway
Q61798677The Differential Roles of T Cells in Non-alcoholic Fatty Liver Disease and Obesity
Q41865644The benefits of restraint: a pivotal role for IL-13 in hepatic glucose homeostasis
Q36954679The endoplasmic reticulum as a potential therapeutic target in nonalcoholic fatty liver disease
Q37581353The microbiota maintain homeostasis of liver-resident γδT-17 cells in a lipid antigen/CD1d-dependent manner
Q27023425The regulatory role of invariant NKT cells in tumor immunity
Q41904044The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis
Q37825926The unfolded protein response: how protein folding became a restrictive aspect for innate immunity and B lymphocytes
Q38894017Type II NKT cells: a distinct CD1d-restricted immune regulatory NKT cell subset.
Q33904744α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes