scholarly article | Q13442814 |
P50 | author | Laurie Glimcher | Q6501587 |
Juan R Cubillos-Ruiz | Q89307921 | ||
Sarah E Bettigole | Q125299143 | ||
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Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma | Q24598483 | ||
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Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease | Q24628936 | ||
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy | Q24655821 | ||
Ligand-independent activation of estrogen receptor alpha by XBP-1 | Q24678871 | ||
Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors | Q27640568 | ||
Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity | Q27702249 | ||
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells | Q28155919 | ||
ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis | Q28389316 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis | Q28589300 | ||
An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering | Q29615505 | ||
Molecular mechanisms of human IRE1 activation through dimerization and ligand binding | Q30404387 | ||
Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma | Q30496396 | ||
Paneth cells as a site of origin for intestinal inflammation. | Q30559414 | ||
IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level | Q33707431 | ||
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway | Q33926690 | ||
Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells. | Q34104084 | ||
The transcription factor XBP1 is selectively required for eosinophil differentiation | Q34483620 | ||
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. | Q34572339 | ||
Nanomolecular targeting of dendritic cells for ovarian cancer therapy | Q34663940 | ||
Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
Ovarian cancer progression is controlled by phenotypic changes in dendritic cells | Q35826026 | ||
Lipid peroxidation product 4-hydroxy-trans-2-nonenal causes endothelial activation by inducing endoplasmic reticulum stress | Q35879593 | ||
Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy | Q35909430 | ||
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer. | Q36643661 | ||
The role of X-box binding protein-1 in tumorigenicity. | Q37553966 | ||
Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway | Q37648367 | ||
Targeting the unfolded protein response in disease. | Q38132652 | ||
Endoplasmic reticulum stress in immunity | Q38286013 | ||
Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic | Q38873500 | ||
Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival | Q38996766 | ||
Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines. | Q40101179 | ||
Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability | Q41884011 | ||
Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer | Q46665995 | ||
Cytochemical and immunocytochemical characterization of blood cells and immunohistochemical analysis of spleen cells from 2 species of frog, Rana (Aquarana) catesbeiana and Xenopus laevis | Q46669350 | ||
Trierixin, a novel Inhibitor of ER stress-induced XBP1 activation from Streptomyces sp. 1. Taxonomy, fermentation, isolation and biological activities | Q46965775 | ||
Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis | Q83392806 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | dendritic cell | Q506253 |
P304 | page(s) | 2121-6 | |
P577 | publication date | 2016-05-01 | |
P1433 | published in | Clinical Cancer Research | Q332253 |
P1476 | title | Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment | |
P478 | volume | 22 |
Q98778664 | Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma |
Q91738709 | Application of a New Multiplexed Array for Rapid, Sensitive, Simultaneous and Quantitative Assessment of Spliced and Unspliced XBP1 |
Q90129866 | Generation of in situ sequencing based OncoMaps to spatially resolve gene expression profiles of diagnostic and prognostic markers in breast cancer |
Q42319225 | Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression |
Q30252210 | Recent insights into the implications of metabolism in plasmacytoid dendritic cell innate functions: Potential ways to control these functions |
Q47738152 | Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies |
Q90080201 | Type I interferons and endoplasmic reticulum stress in health and disease |
Q64883325 | Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells. |
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