| scholarly article | Q13442814 |
| P2093 | author name string | D Thomas Rutkowski | |
| Heather M Tyra | |||
| Diane DeZwaan McCabe | |||
| Madhusudana R Chikka | |||
| P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
| Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding | Q22065896 | ||
| Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response | Q24290935 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development | Q24292104 | ||
| Roles of CHOP/GADD153 in endoplasmic reticulum stress | Q24302185 | ||
| C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene | Q24336614 | ||
| Atf4 regulates obesity, glucose homeostasis, and energy expenditure | Q24648259 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
| Proteasome inhibitors disrupt the unfolded protein response in myeloma cells | Q28155919 | ||
| Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance | Q28244602 | ||
| A simple method for the rapid generation of recombinant adenovirus vectors | Q40871252 | ||
| The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis | Q41791624 | ||
| Endoplasmic reticulum stress promotes LIPIN2-dependent hepatic insulin resistance | Q41889666 | ||
| The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis | Q41904044 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | Q42451739 | ||
| ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
| A feedback transcriptional mechanism controls the level of the arginine/lysine transporter cat-1 during amino acid starvation | Q42976044 | ||
| Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance | Q61993990 | ||
| Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
| Involvement of endoplasmic stress protein C/EBP homologous protein in arteriosclerosis acceleration with augmented biological stress responses | Q84654008 | ||
| Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase | Q28280649 | ||
| Physical and functional association between GADD153 and CCAAT/enhancer-binding protein beta during cellular stress | Q28281869 | ||
| CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription | Q28287446 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes | Q28506402 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
| Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element | Q28570085 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis | Q28586997 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
| Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress | Q29615495 | ||
| Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins | Q33262919 | ||
| Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway | Q33264756 | ||
| ER stress-inducible factor CHOP affects the expression of hepcidin by modulating C/EBPalpha activity | Q33492751 | ||
| Regulation of basal cellular physiology by the homeostatic unfolded protein response | Q33886820 | ||
| Glycogen synthase kinase 3 is an insulin-regulated C/EBPalpha kinase | Q33960787 | ||
| Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis | Q33963803 | ||
| Transcriptional regulation of metabolism | Q34511703 | ||
| Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stress | Q35790896 | ||
| Endoplasmic reticulum stress in liver disease | Q36031838 | ||
| Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
| Bortezomib: proteasome inhibition as an effective anticancer therapy | Q36366801 | ||
| gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3. | Q36573685 | ||
| IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis | Q36600595 | ||
| Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents | Q36761728 | ||
| Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the | Q36825517 | ||
| Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Q36861224 | ||
| CHOP and the endoplasmic reticulum stress response in myelinating glia | Q37455379 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| Gene expression profiling identifies a role for CHOP during inhibition of the mitochondrial respiratory chain | Q38355681 | ||
| Expression and function of C/EBP homology protein (GADD153) in podocytes | Q38404766 | ||
| Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 | Q39315996 | ||
| Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| P1104 | number of pages | 11 | |
| P304 | page(s) | 4405-4415 | |
| P577 | publication date | 2012-12-31 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver | |
| P478 | volume | 288 |
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| Q41552256 | Avian reovirus S1133-induced apoptosis is associated with Bip/GRP79-mediated Bim translocation to the endoplasmic reticulum |
| Q39726227 | C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis. |
| Q35067403 | CCAAT/enhancer-binding protein homologous (CHOP) protein promotes carcinogenesis in the DEN-induced hepatocellular carcinoma model |
| Q52939905 | CHOP deficiency prevents methylglyoxal-induced myocyte apoptosis and cardiac dysfunction. |
| Q38608106 | CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy |
| Q45067747 | CHOP-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury |
| Q50968208 | ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis. |
| Q33620277 | ER stress and hepatic lipid metabolism |
| Q36954378 | ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. |
| Q51015129 | Endoplasmic Reticulum Stress-Induced CHOP Inhibits PGC-1α and Causes Mitochondrial Dysfunction in Diabetic Embryopathy. |
| Q94678393 | Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver |
| Q37132517 | Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression |
| Q28818754 | Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression |
| Q54115847 | GCN2 deficiency ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and myocardial oxidative stress. |
| Q47724506 | Hepatic Amiodarone Lipotoxicity Is Ameliorated by Genetic and Pharmacological Inhibition of Endoplasmatic Reticulum Stress |
| Q91857317 | Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration |
| Q49843619 | Liver function and dysfunction - a unique window into the physiological reach of ER stress and the unfolded protein response |
| Q34203031 | Liver transcriptome analysis in gilthead sea bream upon exposure to low temperature |
| Q40041724 | Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene. |
| Q37027025 | Overexpression of CHOP in Myelinating Cells Does Not Confer a Significant Phenotype under Normal or Metabolic Stress Conditions. |
| Q36224716 | PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma. |
| Q91740491 | Regulation of the homeostasis of hepatic endoplasmic reticulum and cytochrome P450 enzymes by autophagy |
| Q37352508 | Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences. |
| Q26765518 | Role of endoplasmic reticulum stress in drug-induced toxicity |
| Q59654517 | Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not w |
| Q37512024 | Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α |
| Q58694274 | TFAP2 transcription factors are regulators of lipid droplet biogenesis |
| Q46533109 | Taurine protects cisplatin induced cardiotoxicity by modulating inflammatory and endoplasmic reticulum stress responses |
| Q42970598 | Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network |
| Q38904460 | The effect of glucose concentration and sodium phenylbutyrate treatment on mitochondrial bioenergetics and ER stress in 3T3-L1 adipocytes |
| Q27319729 | The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis |
| Q38162132 | The unfolded protein response in fatty liver disease |
| Q28087036 | Tumor progression and the different faces of the PERK kinase |
| Q28551023 | XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease |
| Q35184221 | piggyBac-mediated phenotypic correction of factor VIII deficiency |
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