ER stress and hepatic lipid metabolism

scientific article

ER stress and hepatic lipid metabolism is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FGENE.2014.00112
P932PMC publication ID4023072
P698PubMed publication ID24847353
P5875ResearchGate publication ID262532581

P2093author name stringHuiping Zhou
Runping Liu
P2860cites workEndoplasmic reticulum stress: a new pathway to induce autophagy.Q51997673
GRP78 overproduction in pancreatic beta cells protects against high-fat-diet-induced diabetes in mice.Q53117103
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1Q80979487
ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosisQ84283864
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPsQ24290776
Roles of CHOP/GADD153 in endoplasmic reticulum stressQ24302185
Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ERQ24305459
Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein responseQ24548363
Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesisQ24554492
Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesisQ24631468
Endoplasmic reticulum stress and the inflammatory basis of metabolic diseaseQ24633352
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to InsigQ24683936
Endoplasmic reticulum stress and inflammationQ26825586
The interaction of hepatic lipid and glucose metabolism in liver diseasesQ26827770
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signalingQ27008029
The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesisQ27319729
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the GolgiQ28217040
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factorQ28238069
Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1Q28276509
SREBP transcription factors: master regulators of lipid homeostasisQ28297603
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulumQ28512249
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networksQ28591575
Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studiesQ28611460
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein responseQ28611502
Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genesQ28646418
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liverQ29547646
Autophagy is activated for cell survival after endoplasmic reticulum stressQ29614485
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stressQ29615495
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
Autophagy and Regulation of Lipid MetabolismQ33738505
The UPR and cell fate at a glanceQ33748582
Hepatic insig-1 or -2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rats and in fasted/refed normal ratsQ33782820
The emerging role of autophagy in alcoholic liver disease.Q33894424
Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathwayQ34128069
The SREBP pathway--insights from Insigs and insectsQ34223258
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feedingQ34524224
HIV protease inhibitors disrupt lipid metabolism by activating endoplasmic reticulum stress and inhibiting autophagy activity in adipocytesQ34637857
Endoplasmic reticulum architecture: structures in flux.Q34684405
The contribution of endoplasmic reticulum stress to liver diseasesQ34860549
Autophagy in nonalcoholic steatohepatitisQ35014344
SREBPs: transcriptional mediators of lipid homeostasisQ35176927
Endoplasmic reticulum stress triggers autophagyQ35690087
Inflammation, endoplasmic reticulum stress, autophagy, and the monocyte chemoattractant protein-1/CCR2 pathwayQ35691449
Lipid metabolism in hepatic steatosisQ35872185
The unfolded protein response--a stress signaling pathway of the endoplasmic reticulumQ35885345
Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model.Q35907138
Fatty acid regulation of hepatic lipid metabolismQ35975409
Endoplasmic reticulum stress in liver diseaseQ36031838
Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.Q36065244
Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis.Q36366205
Signalling mechanisms linking hepatic glucose and lipid metabolismQ36485655
The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in miceQ36592437
C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liverQ36596344
The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox controlQ36598776
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasisQ36600595
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.Q36870862
Functions of autophagy in hepatic and pancreatic physiology and diseaseQ36948885
Endoplasmic reticulum stress and liver injuryQ36989688
Identification of a novel endoplasmic reticulum stress response element regulated by XBP1.Q37012441
Endoplasmic reticulum stress responsesQ37014237
How IRE1 reacts to ER stressQ37055568
ATF4 protein deficiency protects against high fructose-induced hypertriglyceridemia in mice.Q37132127
Liver lipid metabolismQ37162701
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stressQ37275199
Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD).Q37281827
The evolution of plasma cholesterol: direct utility or a "spandrel" of hepatic lipid metabolism?Q37339419
The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein responseQ37430626
GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.Q37714508
Bile acids as regulators of hepatic lipid and glucose metabolismQ37749352
Endoplasmic Reticulum Stress and Inflammation in Obesity and DiabetesQ37784942
Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases.Q37804462
FoxO1 and hepatic lipid metabolismQ37805344
From chronic overfeeding to hepatic injury: role of endoplasmic reticulum stress and inflammationQ37833343
Endoplasmic reticulum stress and lipid dysregulationQ37834712
Endoplasmic reticulum stress, obesity and diabetesQ37926034
The interplay between endoplasmic reticulum stress and inflammation.Q37976265
Autophagy, signaling and obesityQ38043856
Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitisQ38064611
Cholesterol biosynthesis and ER stress in peroxisome deficiencyQ38161255
GRP78 suppresses lipid peroxidation and promotes cellular antioxidant levels in glial cells following hydrogen peroxide exposure.Q39029371
Does endoplasmic reticulum stress participate in APD-induced hepatic metabolic dysregulation?Q39472674
Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cellsQ39640835
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Glucose regulation of GRP78 gene expressionQ40999351
Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafishQ41764630
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cellsQ41962104
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Regulation of apoptosis by the unfolded protein response.Q42159220
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stressQ42451739
Hepatic autophagy mediates endoplasmic reticulum stress-induced degradation of misfolded apolipoprotein B.Q42484587
Tauroursodeoxycholate (TUDCA), chemical chaperone, enhances function of islets by reducing ER stressQ43028677
Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver diseaseQ44106485
HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes.Q44922052
Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptorQ45200756
Regulation of hepatic Insig-2 by the farnesoid X receptorQ46146959
Lipid metabolism: reviews of HDL and cholesterol efflux, ethanol and hepatic lipid metabolism and lipid disorders during childhoodQ46184346
CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injuryQ46823993
Attenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency.Q51767284
P304page(s)112
P577publication date2014-05-09
P1433published inFrontiers in GeneticsQ2499875
P1476titleER stress and hepatic lipid metabolism
P478volume5

Reverse relations

cites work (P2860)
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