| scholarly article | Q13442814 |
| P50 | author | Arya M Sharma | Q91790562 |
| P2093 | author name string | Richard C Austin | |
| Sárka Lhoták | |||
| Sana Basseri | |||
| P2860 | cites work | Medical Consequences of Obesity | Q22241663 |
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade | Q28211233 | ||
| The retinoblastoma-histone deacetylase 3 complex inhibits PPARgamma and adipocyte differentiation | Q28217285 | ||
| Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment | Q28235209 | ||
| Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress | Q28302176 | ||
| A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress | Q28306995 | ||
| Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 | Q28507338 | ||
| PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| The mammalian unfolded protein response | Q29547400 | ||
| Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
| Adipocyte insensitivity syndromes -- novel approach to nutritional metabolic problems including obesity and obesity related disorders | Q33340847 | ||
| Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals | Q33345339 | ||
| Secretory, endocrine and autocrine/paracrine function of the adipocyte | Q34101093 | ||
| Role of endoplasmic reticulum stress in acrolein-induced endothelial activation | Q34113288 | ||
| Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter. | Q34487321 | ||
| An established preadipose cell line and its differentiation in culture II. Factors affecting the adipose conversion | Q34509691 | ||
| Translational control of gene expression and disease | Q35019684 | ||
| The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response | Q35170906 | ||
| Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: a dose escalation and pharmacologic study | Q35800437 | ||
| The unfolded protein response--a stress signaling pathway of the endoplasmic reticulum | Q35885345 | ||
| Signal sequence mutation in autosomal dominant form of hypoparathyroidism induces apoptosis that is corrected by a chemical chaperone | Q36288999 | ||
| Histone deacetylase inhibitors: a novel target of anticancer therapy (review). | Q36360003 | ||
| Endoplasmic reticulum stress signaling in disease | Q36610455 | ||
| The epidemic of obesity in children and adolescents in the world. | Q36715623 | ||
| Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease | Q36910684 | ||
| Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects | Q36971939 | ||
| Wnt/beta-catenin signaling in adipogenesis and metabolism. | Q36998616 | ||
| Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss | Q37105351 | ||
| The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences | Q37147602 | ||
| GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
| Adipose tissue: a motor for the inflammation associated with obesity | Q37225314 | ||
| The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia | Q37325272 | ||
| Adipose tissue inflammation and liver pathology in human obesity | Q37386088 | ||
| Adipose conversion of 3T3 cells depends on a serum factor | Q37596763 | ||
| Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice | Q38292063 | ||
| Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation | Q38303256 | ||
| Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex | Q39756473 | ||
| Endoplasmic reticulum stress induces leptin resistance | Q39945899 | ||
| Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
| Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation | Q40108203 | ||
| Arginase induction by sodium phenylbutyrate in mouse tissues and human cell lines | Q40239125 | ||
| Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors | Q40277377 | ||
| AMPK activation regulates apoptosis, adipogenesis, and lipolysis by eIF2alpha in adipocytes | Q40336306 | ||
| ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity | Q40386955 | ||
| The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes. | Q40453939 | ||
| Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). | Q40789492 | ||
| Endocrinopathies in the family of endoplasmic reticulum (ER) storage diseases: disorders of protein trafficking and the role of ER molecular chaperones | Q41756384 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Down-regulation of histone deacetylases stimulates adipocyte differentiation | Q42806234 | ||
| Unexpected blockade of adipocyte differentiation by K-7174: implication for endoplasmic reticulum stress. | Q42824612 | ||
| Hormonal regulation of stearoyl coenzyme A desaturase activity and lipogenesis during adipose conversion of 3T3-L1 cells. | Q42824720 | ||
| Distinct transcriptional profiles of adipogenesis in vivo and in vitro | Q42827325 | ||
| Inhibition of histone deacetylase activity by valproic acid blocks adipogenesis | Q42831163 | ||
| NF-kappaB is involved in the TNF-alpha induced inhibition of the differentiation of 3T3-L1 cells by reducing PPARgamma expression | Q42833478 | ||
| Induction of fetal hemoglobin synthesis in children with sickle cell anemia on low-dose oral sodium phenylbutyrate therapy | Q44240572 | ||
| A chemical chaperone 4-PBA ameliorates palmitate-induced inhibition of glucose-stimulated insulin secretion (GSIS). | Q44449038 | ||
| Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids | Q44932422 | ||
| Sodium 4-phenylbutyrate protects against cerebral ischemic injury. | Q44958776 | ||
| Understanding adipocyte differentiation | Q46119331 | ||
| Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 | ||
| Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice | Q46526611 | ||
| Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice | Q46663069 | ||
| Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis | Q46695184 | ||
| Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder. | Q46696120 | ||
| BAX inhibitor-1 modulates endoplasmic reticulum stress-mediated programmed cell death in Arabidopsis | Q46881376 | ||
| Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone. | Q48188803 | ||
| Combination of cytotoxic-differentiation therapy with 5-fluorouracil and phenylbutyrate in patients with advanced colorectal cancer. | Q50457804 | ||
| Obesity, inflammation, and macrophages. | Q51734587 | ||
| Pulsed-dosing with oral sodium phenylbutyrate increases hemoglobin F in a patient with sickle cell anemia. | Q53575121 | ||
| Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR | Q73426609 | ||
| Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate | Q77556982 | ||
| Sodium 4-phenylbutyrate upregulates ENaC and sodium absorption in T84 cells | Q79349169 | ||
| Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 | Q80553475 | ||
| Stability of extemporaneously prepared sodium phenylbutyrate oral suspensions | Q80581945 | ||
| Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats | Q80984872 | ||
| The ER function BiP is a master regulator of ER function | Q81006325 | ||
| P433 | issue | 12 | |
| P921 | main subject | molecular chaperones | Q422496 |
| adipogenesis | Q2824461 | ||
| P304 | page(s) | 2486-2501 | |
| P577 | publication date | 2009-12-01 | |
| P1433 | published in | Journal of Lipid Research | Q6295449 |
| P1476 | title | The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response | |
| P478 | volume | 50 |
| Q51454891 | 4-Phenyl butyric acid prevents glucocorticoid-induced osteoblast apoptosis by attenuating endoplasmic reticulum stress. |
| Q39035105 | 4-Phenylbutyrate inhibits tunicamycin-induced acute kidney injury via CHOP/GADD153 repression |
| Q58591803 | 4-Phenylbutyric Acid Protects Ethanol-induced Damage in the Developing Mouse Brain |
| Q33641274 | A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress |
| Q34200776 | A role for phospholipase D3 in myotube formation |
| Q28477818 | A therapeutic chemical chaperone inhibits cholera intoxication and unfolding/translocation of the cholera toxin A1 subunit |
| Q42804891 | Activating transcription factor 4 regulates adipocyte differentiation via altering the coordinate expression of CCATT/enhancer binding protein β and peroxisome proliferator-activated receptor γ. |
| Q35913725 | Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. |
| Q36283676 | Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress. |
| Q34575683 | Adenylate Kinase 2 Links Mitochondrial Energy Metabolism to the Induction of the Unfolded Protein Response |
| Q35895767 | Amelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a "chemical chaperone" in human THP-1 monocytes |
| Q39012545 | An update on the use of benzoate, phenylacetate and phenylbutyrate ammonia scavengers for interrogating and modifying liver nitrogen metabolism and its implications in urea cycle disorders and liver disease |
| Q64951696 | Angiotensin II Increases Endoplasmic Reticulum Stress in Adipose Tissue and Adipocytes. |
| Q61456219 | Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions |
| Q36384602 | Attenuation of ER stress prevents post-infarction-induced cardiac rupture and remodeling by modulating both cardiac apoptosis and fibrosis |
| Q92561679 | Bardet-Biedl syndrome obesity: BBS4 regulates cellular ER stress in early adipogenesis |
| Q34387568 | Beta-mecaptoethanol suppresses inflammation and induces adipogenic differentiation in 3T3-F442A murine preadipocytes |
| Q36191602 | Blockade of Interplay between IL-17A and Endoplasmic Reticulum Stress Attenuates LPS-Induced Lung Injury |
| Q36630651 | Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription |
| Q36843284 | CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development. |
| Q28540631 | Chaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpression |
| Q89138157 | Chemical chaperone treatment improves levels and distributions of connexins in Cx50D47A mouse lenses |
| Q28080433 | Crosstalk between the unfolded protein response and NF-κB-mediated inflammation in the progression of chronic kidney disease |
| Q49189635 | Crystal structure analysis of human serum albumin complexed with sodium 4-phenylbutyrate |
| Q39655608 | Cyclin G2 regulates adipogenesis through PPAR gamma coactivation |
| Q28389108 | Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver |
| Q39789909 | Detecting and quantitating physiological endoplasmic reticulum stress |
| Q90024736 | Diet-induced hepatic steatosis abrogates cell-surface LDLR by inducing de novo PCSK9 expression in mice |
| Q38980237 | Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells |
| Q33950008 | Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition |
| Q38584194 | Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions |
| Q33620277 | ER stress and hepatic lipid metabolism |
| Q36709748 | ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice |
| Q39139204 | Endoplasmic Reticulum (ER) Stress and Endocrine Disorders. |
| Q47171631 | Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells |
| Q40445739 | Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism. |
| Q35614922 | Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential |
| Q24633352 | Endoplasmic reticulum stress and the inflammatory basis of metabolic disease |
| Q50643277 | Endoplasmic reticulum stress is increased after spontaneous labor in human fetal membranes and myometrium where it regulates the expression of prolabor mediators. |
| Q35306325 | Endoplasmic reticulum stress is increased in adipose tissue of women with gestational diabetes |
| Q26795753 | Essential roles of four-carbon backbone chemicals in the control of metabolism |
| Q60922858 | Exploring Novel Functions of the Small GTPase Ypt1p under Heat-Shock by Characterizing a Temperature-Sensitive Mutant Yeast Strain, |
| Q47175573 | Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. |
| Q39804171 | GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis. |
| Q38802501 | Gene regulation and genetics in neurochemistry, past to future. |
| Q38729322 | Glucosamine induces ER stress by disrupting lipid-linked oligosaccharide biosynthesis and N-linked protein glycosylation |
| Q33556664 | Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance |
| Q34358474 | Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis |
| Q51509652 | Heat stress in pigs is accompanied by adipose tissue-specific responses that favor increased triglyceride storage. |
| Q91062570 | Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases |
| Q41324853 | High content screening for non-classical peroxisome proliferators |
| Q60195653 | Histone Deacetylase Inhibitor (HDACi) Conjugated Polycaprolactone for Combination Cancer Therapy |
| Q59336511 | In vitro culture expansion impairs chondrogenic differentiation and the therapeutic effect of mesenchymal stem cells by regulating the unfolded protein response |
| Q35563335 | Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells |
| Q27015015 | Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases |
| Q35845602 | Label-free profiling of white adipose tissue of rats exhibiting high or low levels of intrinsic exercise capacity. |
| Q34978988 | Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways. |
| Q36680938 | Leptin-based adjuvants: an innovative approach to improve vaccine response |
| Q36477235 | Loss of TDAG51 results in mature-onset obesity, hepatic steatosis, and insulin resistance by regulating lipogenesis |
| Q33899037 | Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance |
| Q37724014 | Modulation of adipocyte differentiation by omega-3 polyunsaturated fatty acids involves the ubiquitin-proteasome system |
| Q38605323 | Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors |
| Q39996279 | No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease. |
| Q49358405 | Nonthermal plasma treated solution inhibits adipocyte differentiation and lipogenesis in 3T3-L1 preadipocytes via ER stress signal suppression |
| Q41248481 | Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue |
| Q37282863 | Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol |
| Q36087653 | Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells |
| Q26769765 | Pharmacological Modulators of Endoplasmic Reticulum Stress in Metabolic Diseases |
| Q50014672 | Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases |
| Q39282297 | Phenylbutyrate and β-cell function: contribution of histone deacetylases and ER stress inhibition. |
| Q28472833 | Phenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cells |
| Q34328371 | Role of ER stress in ventricular contractile dysfunction in type 2 diabetes |
| Q28397185 | Role of fatty-acid synthesis in dendritic cell generation and function |
| Q58611393 | Selenate Prevents Adipogenesis through Induction of Selenoprotein S and Attenuation of Endoplasmic Reticulum Stress |
| Q41345156 | Sodium 4-phenylbutyrate ameliorates the effects of cataract-causing mutant gammaD-crystallin in cultured cells. |
| Q53028251 | Sodium 4-phenylbutyrate reduces myofiber damage in a mouse model of Duchenne muscular dystrophy. |
| Q34257693 | Sodium phenylbutyrate decreases plasma branched-chain amino acids in patients with urea cycle disorders |
| Q30401515 | Species Differences in the Binding of Sodium 4-Phenylbutyrate to Serum Albumin |
| Q38792057 | Stage-dependent effects of exogenous TRAIL on atherogenesis: role of ER stress-mediated sensitization of macrophage apoptosis |
| Q37679694 | Strategies for treating idiopathic pulmonary fibrosis |
| Q40258446 | Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes |
| Q48231735 | Supra-pharmacological concentration of capsaicin stimulates brown adipogenesis through induction of endoplasmic reticulum stress |
| Q39037381 | Sustained endoplasmic reticulum stress inhibits hepatocyte proliferation via downregulation of c-Met expression |
| Q41688608 | The Unfolded Protein Response in Amelogenesis and Enamel Pathologies |
| Q38904460 | The effect of glucose concentration and sodium phenylbutyrate treatment on mitochondrial bioenergetics and ER stress in 3T3-L1 adipocytes |
| Q36062081 | The impact of the unfolded protein response on human disease |
| Q33660253 | The quality control theory of aging |
| Q28587096 | The role of adipocyte XBP1 in metabolic regulation during lactation |
| Q36905171 | The zebrafish as a model to study polycystic liver disease |
| Q39759924 | Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R alphaA-crystallin |
| Q38811051 | Tubby-like protein superfamily member PLSCR3 functions as a negative regulator of adipogenesis in mouse 3T3-L1 preadipocytes by suppressing induction of late differentiation stage transcription factors |
| Q55025358 | Tumor Necrosis Factor-α Attenuates the Osteogenic Differentiation Capacity of Periodontal Ligament Stem Cells by Activating PERK Signaling. |
| Q89296168 | Tyrosine411 and Arginine410 of Human Serum Albumin Play an Important Role in the Binding of Sodium 4-Phenylbutyrate to Site II |
| Q42820945 | X-box binding protein 1 enhances adipogenic differentiation of 3T3-L1 cells through the downregulation of Wnt10b expression |
| Q42835425 | X-box binding protein 1 is a novel key regulator of peroxisome proliferator-activated receptor γ2. |
| Q36865120 | miR-148a is a downstream effector of X-box-binding protein 1 that silences Wnt10b during adipogenesis of 3T3-L1 cells. |
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