| scholarly article | Q13442814 |
| P2093 | author name string | Richard C Austin | |
| Sana Basseri | |||
| P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
| Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta | Q22011091 | ||
| ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis | Q24554492 | ||
| A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood | Q24614744 | ||
| Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis | Q27489896 | ||
| Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins | Q27932183 | ||
| Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
| Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1 | Q28276509 | ||
| Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c | Q28297047 | ||
| SREBP transcription factors: master regulators of lipid homeostasis | Q28297603 | ||
| Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways | Q28365886 | ||
| Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice | Q28476015 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
| Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice. | Q51021977 | ||
| Metabolic syndrome and acute hyperglycemia are associated with endoplasmic reticulum stress in human mononuclear cells. | Q51372559 | ||
| Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 | Q80553475 | ||
| Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
| The ER function BiP is a master regulator of ER function | Q81006325 | ||
| Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis | Q81441036 | ||
| ATF4 regulates lipid metabolism and thermogenesis | Q82468721 | ||
| Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes | Q42828051 | ||
| Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis. | Q42832143 | ||
| Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress | Q42906567 | ||
| Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells | Q43206333 | ||
| Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease | Q43648215 | ||
| Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells | Q44892719 | ||
| Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways | Q44927719 | ||
| Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids | Q44932422 | ||
| Sodium 4-phenylbutyrate protects against cerebral ischemic injury. | Q44958776 | ||
| Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 | ||
| Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. | Q46442905 | ||
| Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis | Q46695184 | ||
| The unfolded protein response in health and disease | Q47682274 | ||
| Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone. | Q48188803 | ||
| Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid beta-peptide-induced apoptosis. | Q48521410 | ||
| Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
| Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells | Q40313352 | ||
| Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c | Q40507727 | ||
| Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12. | Q40575348 | ||
| Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). | Q40789492 | ||
| The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis | Q41058776 | ||
| PPARγ and the control of adipogenesis | Q41519414 | ||
| Leptin, leptin receptors, and the control of body weight. | Q41752514 | ||
| The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis | Q41904044 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | Q42451739 | ||
| ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles | Q28581484 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
| Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes | Q28646399 | ||
| Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls | Q29547730 | ||
| Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
| Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals | Q33345339 | ||
| Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex | Q33553700 | ||
| A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress | Q33641274 | ||
| The cellular response to protein misfolding in the endoplasmic reticulum. | Q33706901 | ||
| APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation | Q34001437 | ||
| Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. | Q34024266 | ||
| Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity | Q34181503 | ||
| On the mechanism of sensing unfolded protein in the endoplasmic reticulum | Q34230593 | ||
| Inhibitors of histone deacetylase as new anticancer agents | Q34372944 | ||
| Influence of molecular and chemical chaperones on protein folding | Q34432453 | ||
| Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans | Q34615491 | ||
| Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts | Q34667420 | ||
| Intersection of the unfolded protein response and hepatic lipid metabolism | Q34985745 | ||
| Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis | Q35003607 | ||
| Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease | Q35055531 | ||
| Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress | Q35120044 | ||
| Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma. | Q35187142 | ||
| Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi | Q35644888 | ||
| The unfolded protein response--a stress signaling pathway of the endoplasmic reticulum | Q35885345 | ||
| Phenylbutyric acid suppresses protein accumulation-mediated ER stress in retrovirus-infected astrocytes and delays onset of paralysis in infected mice | Q36108977 | ||
| Store-operated calcium entry in physiology and pathology of mammalian cells. | Q36149611 | ||
| Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents | Q36183590 | ||
| XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
| Role of cholesterol and lipid organization in disease | Q36327808 | ||
| Lipid metabolism in the liver. | Q36712398 | ||
| Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects | Q36971939 | ||
| Endoplasmic reticulum stress and liver injury | Q36989688 | ||
| Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss | Q37105351 | ||
| Liver lipid metabolism | Q37162701 | ||
| GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
| The endoplasmic reticulum stress response in immunity and autoimmunity | Q37231726 | ||
| Transcriptional regulation of hepatic fatty acid metabolism | Q37254287 | ||
| ATF6 modulates SREBP2-mediated lipogenesis. | Q37260315 | ||
| Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression | Q37277355 | ||
| Mechanisms of disease progression in nonalcoholic fatty liver disease | Q37310288 | ||
| The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts | Q37328439 | ||
| Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions | Q37335994 | ||
| Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a | Q37360326 | ||
| Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. | Q37382401 | ||
| The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response | Q37430626 | ||
| Molecular mechanisms involved in NAFLD progression | Q37437295 | ||
| Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis | Q37465347 | ||
| Endoplasmic reticulum stress and renal disease | Q37512291 | ||
| Endoplasmic reticulum stress in disease: mechanisms and therapeutic opportunities | Q37603369 | ||
| ER stress in cardiovascular disease | Q37632850 | ||
| Cytochrome P450 proteins: retention and distribution from the endoplasmic reticulum. | Q37666936 | ||
| Sterol metabolism and SREBP activation | Q37764477 | ||
| Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases. | Q37804462 | ||
| Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease | Q37844020 | ||
| Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice | Q38290693 | ||
| SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease | Q38292429 | ||
| Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis | Q38298207 | ||
| Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis. | Q38309701 | ||
| PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes. | Q38332175 | ||
| Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes | Q38349877 | ||
| Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Q38845249 | ||
| IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. | Q39422225 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis | Q39843795 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| P304 | page(s) | 841362 | |
| P577 | publication date | 2011-12-13 | |
| P1433 | published in | Biochemistry Research International | Q26841801 |
| P1476 | title | Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential | |
| P478 | volume | 2012 |
| Q26774351 | A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis |
| Q64229238 | Astragaloside IV ameliorates endoplasmic reticulum stress‑induced apoptosis of Aβ25‑35‑treated PC12 cells by inhibiting the p38 MAPK signaling pathway |
| Q36597272 | C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4 |
| Q46409576 | Changes in lipidomic profile of aqueous humour in Fuchs endothelial dystrophy |
| Q47813504 | Coordinating Organismal Metabolism During Protein Misfolding in the ER Through the Unfolded Protein Response |
| Q35994348 | Defective triglyceride biosynthesis in CETP-deficient SW872 cells |
| Q39418523 | Drosophila melanogaster activating transcription factor 4 regulates glycolysis during endoplasmic reticulum stress |
| Q36678823 | ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons. |
| Q61796567 | ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness" |
| Q58692697 | Effects of Antioxidants in Reducing Accumulation of Fat in Hepatocyte |
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| Q35729234 | Endoplasmic reticulum membrane potassium channel dysfunction in high fat diet induced stress in rat hepatocytes. |
| Q38989169 | Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA. |
| Q91724597 | Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production |
| Q55004119 | Epigenetics of Subcellular Structure Functioning in the Origin of Risk or Resilience to Comorbidity of Neuropsychiatric and Cardiometabolic Disorders. |
| Q35288559 | Epithelial Xbp1 is required for cellular proliferation and differentiation during mammary gland development |
| Q38069459 | FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival |
| Q92508950 | GRP94 Is Involved in the Lipid Phenotype of Brain Metastatic Cells |
| Q42237860 | GSK-3-mediated phosphorylation couples ER-Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretion |
| Q42657454 | HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD. |
| Q47594156 | Hepatoprotective effect of peony total glucosides and the underlying mechanisms in diabetic rats |
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| Q90311160 | Increased Expression of Lipid Metabolism Genes in Early Stages of Wooden Breast Links Myopathy of Broilers to Metabolic Syndrome in Humans |
| Q44616132 | Indomethacin suppresses LAMP-2 expression and induces lipophagy and lipoapoptosis in rat enterocytes via the ER stress pathway. |
| Q92081629 | Inhibition of endoplasmic reticulum stress ameliorates cardiovascular injury in a rat model of metabolic syndrome |
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| Q36139130 | Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in Mice |
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