scholarly article | Q13442814 |
P356 | DOI | 10.1007/S12035-018-1451-8 |
P698 | PubMed publication ID | 30569418 |
P50 | author | Othman Ghribi | Q61140797 |
P2093 | author name string | Gurdeep Marwarha | |
Jonah Lund | |||
Kate Claycombe-Larson | |||
P2860 | cites work | Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE | Q22010705 |
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism | Q24298588 | ||
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta | Q24598068 | ||
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor | Q28238069 | ||
Alzheimer's disease: the amyloid cascade hypothesis | Q29547160 | ||
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Q29547646 | ||
Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells | Q31582971 | ||
Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation | Q33556064 | ||
Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle | Q33584772 | ||
Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons | Q33762153 | ||
Regulation of hepatic gene expression by saturated fatty acids | Q33816670 | ||
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model | Q33915820 | ||
Dietary n-6 and n-3 polyunsaturated fatty acids: from biochemistry to clinical implications in cardiovascular prevention. | Q34014760 | ||
Dietary fat intake and the risk of incident dementia in the Rotterdam Study | Q34065622 | ||
Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices | Q34075070 | ||
β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway | Q34267894 | ||
In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling | Q34322474 | ||
Insulin reverses the high-fat diet-induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease | Q34428494 | ||
Dietary links to Alzheimer's disease: 1999 update. | Q34817678 | ||
Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells | Q34947624 | ||
Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus | Q35063700 | ||
Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap? | Q35225919 | ||
Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential | Q35614922 | ||
The Effect of a High-Fat Diet on Brain Plasticity, Inflammation and Cognition in Female ApoE4-Knockin and ApoE-Knockout Mice | Q36015429 | ||
Dietary fatty acids intake: possible role in cognitive decline and dementia | Q36093759 | ||
Studies of the effects of high fat diets on cognitive function in a rat model | Q36283934 | ||
Leptin signaling and Alzheimer's disease | Q36576492 | ||
Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR. | Q36683297 | ||
A model for fatty acid transport into the brain. | Q36954182 | ||
Dietary influences on cognitive function with aging: from high-fat diets to healthful eating | Q36994819 | ||
APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease. | Q37078850 | ||
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes | Q37209459 | ||
Liver X receptors in lipid metabolism: opportunities for drug discovery | Q38212170 | ||
Saturated and trans fats and dementia: a systematic review | Q38219298 | ||
SREBP-1 dimerization specificity maps to both the helix-loop-helix and leucine zipper domains: use of a dominant negative | Q38346363 | ||
27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer. | Q38674529 | ||
Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response. | Q38781680 | ||
NF-κB - a friend, a foe, or a bystander - in the neurodegenerative cascade and pathogenesis of Alzheimer's disease. | Q39459051 | ||
Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol | Q39461274 | ||
Dysregulation of SREBP2 induces BACE1 expression. | Q39513077 | ||
ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity | Q40386955 | ||
High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. | Q41881815 | ||
Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway | Q42037546 | ||
High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 mice | Q42123847 | ||
Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets | Q42403132 | ||
Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases | Q42589440 | ||
Fatty acid binding profile of the liver X receptor α. | Q43089720 | ||
Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats | Q43596109 | ||
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease | Q44060098 | ||
Effects of diets enriched in saturated (palmitic), monounsaturated (oleic), or trans (elaidic) fatty acids on insulin sensitivity and substrate oxidation in healthy adults | Q44081081 | ||
Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease | Q44132132 | ||
Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain. | Q46714697 | ||
Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease. | Q46945608 | ||
Palmitate induced C/EBP homologous protein activation leads to NF-κB -mediated increase in BACE1 activity and Amyloid beta genesis. | Q47218201 | ||
Maternal low-protein diet decreases brain-derived neurotrophic factor expression in the brains of the neonatal rat offspring | Q47785961 | ||
The effects of high fat diets and environmental influences on cognitive performance in rats | Q48184315 | ||
Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer's disease. | Q48424176 | ||
Palmitic acid-treated astrocytes induce BACE1 upregulation and accumulation of C-terminal fragment of APP in primary cortical neurons | Q48448879 | ||
High fat diet induces brain insulin resistance and cognitive impairment in mice. | Q48463842 | ||
Caloric intake and the risk of Alzheimer disease | Q48520005 | ||
High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model | Q48877805 | ||
Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice. | Q50976712 | ||
Impact of enriched environment on production of tau, amyloid precursor protein and, amyloid-β peptide in high-fat and high-sucrose-fed rats. | Q51283041 | ||
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. | Q51556346 | ||
Fat intake at midlife and risk of dementia and Alzheimer's disease: a population-based study. | Q53277940 | ||
Cellular model of Alzheimer's disease--relevance to therapeutic testing. | Q53324170 | ||
Leptin decreases lipogenic enzyme gene expression through modification of SREBP-1c gene expression in white adipose tissue of aging rats | Q81039358 | ||
P433 | issue | 7 | |
P304 | page(s) | 5256-5269 | |
P577 | publication date | 2018-12-19 | |
P1433 | published in | Molecular Neurobiology | Q15716645 |
P1476 | title | Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis | |
P478 | volume | 56 |
Q89964410 | Polyunsaturated Fatty Acid Composition of Cerebrospinal Fluid Fractions Shows Their Contribution to Cognitive Resilience of a Pre-symptomatic Alzheimer's Disease Cohort | cites work | P2860 |
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