IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes

scientific article published on 16 November 2015

IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SREP16580
P932PMC publication ID4644985
P698PubMed publication ID26568450
P5875ResearchGate publication ID284022802

P50authorMasayuki KanekoQ55344521
P2093author name stringMin Cui
Xiang Cui
Kazunori Imaizumi
Koji Matsuhisa
Rie Asada
Soshi Kanemoto
Kenta Hino
P2860cites workIdentification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factorsQ22008465
ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1Q22254333
Plasma cell differentiation requires the transcription factor XBP-1Q24291453
Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimersQ24302559
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cellsQ24309442
Classification of human B-ZIP proteins based on dimerization propertiesQ24540084
Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificityQ24562832
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small moleculeQ24596804
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleusQ27930818
Chondrocyte proliferation regulated by secreted luminal domain of ER stress transducer BBF2H7/CREB3L2.Q54448789
Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and InsulinQ60714047
Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiationQ61207006
A time-dependent phase shift in the mammalian unfolded protein responseQ72997174
beta(3)-adrenergic stimulation differentially inhibits insulin signaling and decreases insulin-induced glucose uptake in brown adipocytesQ73212077
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1Q80979487
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinaseQ27938837
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradationQ28131669
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein responseQ28139950
Scissors-grip model for DNA recognition by a family of leucine zipper proteinsQ28272775
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinaseQ28296183
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocationQ28510062
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Cloning of mammalian Ire1 reveals diversity in the ER stress responsesQ28587224
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formationQ28587852
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesisQ28591480
Regulation of glucose homeostasis through a XBP-1-FoxO1 interactionQ28592129
Brown adipose tissue: function and physiological significanceQ29547448
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 geneQ33199648
Towards a molecular understanding of adaptive thermogenesisQ33892351
Thermogenic activation induces FGF21 expression and release in brown adipose tissue.Q34787051
Orchestrating the unfolded protein response in health and diseaseQ35001604
PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolismQ35229188
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasisQ35419603
Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potentialQ35614922
The endoplasmic reticulum stress transducer OASIS is involved in the terminal differentiation of goblet cells in the large intestineQ35868198
ER stress and the unfolded protein responseQ35986601
The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality controlQ36342502
Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domainsQ36712468
Brown fat and the myth of diet-induced thermogenesisQ37726542
Stressed out about obesity: IRE1α-XBP1 in metabolic disordersQ37894253
Brown adipose tissue and its therapeutic potential.Q38203348
Lipid-dependent regulation of the unfolded protein responseQ38301758
Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes.Q39213423
Brown Adipose Tissue: The Dominant Site of Nonshivering Thermogenesis in the RatQ40528983
Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2Q42094437
Adrenergic activation of vascular endothelial growth factor mRNA expression in rat brown adipose tissue: implication in cold-induced angiogenesisQ42159553
Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutationsQ43733971
Cold elicits the simultaneous induction of fatty acid synthesis and beta-oxidation in murine brown adipose tissue: prediction from differential gene expression and confirmation in vivo.Q43871232
The mitochondrial uncoupling-protein homologuesQ50308475
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
P304page(s)16580
P577publication date2015-11-16
P1433published inScientific ReportsQ2261792
P1476titleIRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes
P478volume5

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cites work (P2860)
Q39063540Fibroblast growth factor 21 and its novel association with oxidative stress
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Q38891681White Adipose Tissue Browning: A Double-edged Sword

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