Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model.

scientific article published on 5 March 2012

Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TOXLET.2012.02.017
P932PMC publication ID3334434
P698PubMed publication ID22414386
P5875ResearchGate publication ID221892347

P50authorKezhong ZhangQ64604817
P2093author name stringYouming Xie
Seung-Wook Ha
Ze Zheng
Roberto Mendez
Jin-Sook Lee
P2860cites workEndoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory responseQ24304232
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genesQ24534395
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1Q28276509
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathwaysQ28365886
Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissuesQ28383992
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiationQ28507769
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulumQ28512249
The mammalian unfolded protein responseQ29547400
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liverQ29547646
Steatohepatitis: a tale of two "hits"?Q29547771
Protein folding in the cellQ29547792
Design and validation of a histological scoring system for nonalcoholic fatty liver diseaseQ29614930
Growth of human hepatoma cells lines with differentiated functions in chemically defined mediumQ29617962
Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cellsQ31582971
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteinsQ33262919
Evaluation of real-time PCR endogenous control genes for analysis of gene expression in bovine endometriumQ33514147
Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesionsQ33731663
Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cellsQ33974369
Nonalcoholic steatohepatitis: definition and pathologyQ34215155
Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liverQ34664294
SREBPs: transcriptional mediators of lipid homeostasisQ35176927
Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formationQ35747483
Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in miceQ35870151
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered miceQ36479005
Update on non-alcoholic fatty liver disease in childrenQ36797874
Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and futureQ36895509
Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD).Q37281827
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2Q37622629
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cellsQ40313352
Identification and characterization of endoplasmic reticulum stress-induced apoptosis in vivoQ40385723
Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesisQ40548006
Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factorsQ41208203
Effect of tunicamycin on epidermal glycoprotein and glycosaminoglycan synthesis in vitroQ41879507
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stressQ42451739
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophagesQ44542540
Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factorsQ45219986
Measurement of ER stress response and inflammation in the mouse model of nonalcoholic fatty liver disease.Q54617615
Enzymatic determination of total serum cholesterolQ69744405
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2Q80553475
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosisQ81441036
P433issue1
P921main subjectsteatohepatitisQ2335423
non-alcoholic steatohepatitisQ28692677
P304page(s)29-38
P577publication date2012-03-05
P1433published inToxicology LettersQ1796854
P1476titlePharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model
P478volume211

Reverse relations

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