Docosahexaenoic Acid Ameliorates Fructose-Induced Hepatic Steatosis Involving ER Stress Response in Primary Mouse Hepatocytes

scientific article published on 20 January 2016

Docosahexaenoic Acid Ameliorates Fructose-Induced Hepatic Steatosis Involving ER Stress Response in Primary Mouse Hepatocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/NU8010055
P932PMC publication ID4728666
P698PubMed publication ID26805874
P5875ResearchGate publication ID291368063

P2093author name stringHeng Wang
Jibin Li
Xiaoqiu Xiao
Chuan Peng
Yanbiao Ai
Jinying Zheng
P2860cites workXBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
Fructose consumption as a risk factor for non-alcoholic fatty liver diseaseQ24657933
Fructose as a key player in the development of fatty liver diseaseQ27014596
Evidence against the peroxisome proliferator-activated receptor alpha (PPARalpha) as the mediator for polyunsaturated fatty acid suppression of hepatic L-pyruvate kinase gene transcriptionQ28378046
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
High prevalence of non-alcoholic fatty liver disease in the Chinese - results from the Hong Kong liver health census.Q50468924
Effects of fish oil feeding and fasting on LXRalpha/RXRalpha binding to LXRE in the SREBP-1c promoter in mouse liver.Q51512150
Mitochondrial carnitine palmitoyltransferase I isoform switching in the developing rat heartQ72167695
Mechanisms for the acute effect of fructose on postprandial lipemiaQ80447618
How common is non-alcoholic fatty liver disease in the Asia-Pacific region and are there local differences?Q80470863
Rats fed fructose-enriched diets have characteristics of nonalcoholic hepatic steatosisQ84582749
Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: a randomized controlled trialQ87408172
Atorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase AQ28571317
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoidsQ28728625
What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?Q30361645
Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver diseaseQ34069352
Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.Q34166238
Non-alcoholic steatohepatitis: a microbiota-driven disease.Q34798884
The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.Q35090215
Association of fructose consumption and components of metabolic syndrome in human studies: a systematic review and meta-analysis.Q35139058
Dietary docosahexaenoic acid and eicosapentaenoic acid influence liver triacylglycerol and insulin resistance in rats fed a high-fructose dietQ35548829
Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model.Q35907138
Nonalcoholic fatty liver disease: from steatosis to cirrhosisQ36382279
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered miceQ36479005
Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implicationsQ36617551
Beneficial effects of flaxseed oil and fish oil diet are through modulation of different hepatic genes involved in lipid metabolism in streptozotocin-nicotinamide induced diabetic ratsQ36803841
Dietary sugars stimulate fatty acid synthesis in adultsQ36898127
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humansQ37170824
Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosisQ37229854
Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectinsQ37233208
Non-Alcoholic Fatty Liver Disease (NAFLD): new challenge for general practitioners and important burden for health authorities?Q37714169
The therapeutic potential of long-chain omega-3 fatty acids in nonalcoholic fatty liver diseaseQ37771506
The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver diseaseQ37963122
Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppressionQ38347368
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Malonyl-CoA and carnitine palmitoyltransferase I: an expanding partnershipQ40948900
A rapid two-step method for isolation of functional primary mouse hepatocytes: cell characterization and asialoglycoprotein receptor based assay developmentQ41120756
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stressQ42451739
Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed miceQ42717472
Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): a population based studyQ44451078
Endoplasmic reticulum stress plays a central role in development of leptin resistanceQ46178586
'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognitionQ48585200
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectsteatosisQ1365091
P577publication date2016-01-20
P1433published inNutrientsQ7070485
P1476titleDocosahexaenoic Acid Ameliorates Fructose-Induced Hepatic Steatosis Involving ER Stress Response in Primary Mouse Hepatocytes
P478volume8

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cites work (P2860)
Q91797295Alpha-tocopherol in intravenous lipid emulsions imparts hepatic protection in a murine model of hepatosteatosis induced by the enteral administration of a parenteral nutrition solution
Q37337438Carrot Juice Administration Decreases Liver Stearoyl-CoA Desaturase 1 and Improves Docosahexaenoic Acid Levels, but Not Steatosis in High Fructose Diet-Fed Weanling Wistar Rats
Q58127233Docosahexaenoic Acid Reduces Palmitic Acid-Induced Endoplasmic Reticulum Stress in Pancreatic Β Cells
Q90079540Docosahexaenoic and Eicosapentaenoic Acids Prevent Altered-Muc2 Secretion Induced by Palmitic Acid by Alleviating Endoplasmic Reticulum Stress in LS174T Goblet Cells
Q60950066Effective Food Ingredients for Fatty Liver: Soy Protein β-Conglycinin and Fish Oil
Q45869235FOXA2 alleviates CCl4-induced liver fibrosis by protecting hepatocytes in mice
Q33616674Homocysteine Induces Hepatic Steatosis Involving ER Stress Response in High Methionine Diet-Fed Mice
Q47877023Omega-3 PUFA ameliorates hyperhomocysteinemia-induced hepatic steatosis in mice by inhibiting hepatic ceramide synthesis
Q91971001Potential role of endoplasmic reticulum stress is involved in the protection of fish oil on neonatal rats with necrotizing enterocolitis

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