Stress management: How the unfolded protein response impacts fatty liver disease

scientific article

Stress management: How the unfolded protein response impacts fatty liver disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JHEP.2012.06.018
P3181OpenCitations bibliographic resource ID2480611
P932PMC publication ID3872997
P698PubMed publication ID22732510
P5875ResearchGate publication ID228065785

P2093author name stringDru Imrie
Kirsten C. Sadler
P2860cites workInduction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stressQ42451739
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C.Q44332232
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver diseaseQ44934521
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-IIQ81144490
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistanceQ33556664
Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.Q34024266
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesityQ34181503
Sarco(endo)plasmic reticulum Ca 2+ -ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesityQ34320510
Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humansQ34615491
Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allograftsQ34667420
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.Q35551757
Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model.Q35907138
Endoplasmic reticulum stress in liver diseaseQ36031838
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver diseaseQ37310283
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed miceQ38354947
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Hepatitis C virus, ER stress, and oxidative stressQ40432170
Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafishQ41764630
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in miceQ41825121
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectliver diseaseQ929737
fatty liver diseaseQ6058862
P304page(s)1147-51
P577publication date2012-11-01
P1433published inJournal of HepatologyQ15724402
P1476titleStress management: How the unfolded protein response impacts fatty liver disease
P478volume57

Reverse relations

cites work (P2860)
Q38381594Alcoholic liver disease: mechanisms of injury and targeted treatment
Q33858526Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion.
Q34546956Approaches to imaging unfolded secretory protein stress in living cells
Q33922493Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy
Q36764959Association between betatrophin/ANGPTL8 and non-alcoholic fatty liver disease: animal and human studies
Q54402713Coffee enhances the expression of chaperones and antioxidant proteins in rats with nonalcoholic fatty liver disease.
Q37288073Endoplasmic reticulum stress: its role in disease and novel prospects for therapy
Q37137783Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease
Q60044667Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease
Q34203031Liver transcriptome analysis in gilthead sea bream upon exposure to low temperature
Q33814245Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish
Q57054615New insights into the cellular temporal response to proteostatic stress
Q26796338Zebrafish: an important tool for liver disease research
Q27305199trappc11 is required for protein glycosylation in zebrafish and humans

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