Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors

scientific article published on 11 January 2005

Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00518.2004
P698PubMed publication ID15644462
P5875ResearchGate publication ID8087886

P50authorGrant N. PierceQ39601044
Yaw L. SiowQ42369422
P2093author name stringPatrick C Choy
Gerald Y Minuk
Connie W H Woo
Karmin O
David Mymin
P2860cites workHerp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stressQ22254718
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
DyslipidaemiaQ28205109
Homocysteine and cardiovascular diseaseQ28265188
Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated by cellular redoxQ28296315
Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genesQ28297991
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathwaysQ28365886
Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemiaQ28506932
A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase geneQ28646525
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liverQ29547646
Complete chromogen separation and analysis in double immunohistochemical stains using Photoshop-based image analysisQ31951969
A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.Q34202341
Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine StudyQ34288393
Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM.Q34610932
Advances in the Understanding and Treatment of Nonalcoholic Fatty Liver DiseaseQ35580451
Nutrient regulation of gene expression by the sterol regulatory element binding proteins: increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivoQ35770031
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.Q37382401
Nuclear factor-kappa B and mitogen-activated protein kinases mediate nitric oxide-enhanced transcriptional expression of interferon-betaQ38359315
Kinetic analysis of the individual reductive steps catalyzed by β-hydroxy-β-methylglutaryl-coenzyme A reductase obtained from yeastQ39111871
Regenerating livers of old rats contain high levels of C/EBPalpha that correlate with altered expression of cell cycle associated proteinsQ39724437
Homocysteine stimulates the production and secretion of cholesterol in hepatic cellsQ41006862
Isolation and characterization of hepatocytes and Kupffer cellsQ41689087
Insulin stimulates cAMP-response element binding protein activity in HepG2 and 3T3-L1 cell lines.Q42832527
Relative roles of albumin and ceruloplasmin in the formation of homocystine, homocysteine-cysteine-mixed disulfide, and cystine in circulationQ43761093
A role for cyclic AMP response element-binding protein (CREB) but not the highly similar ATF-2 protein in sterol regulation of the promoter for 3-hydroxy-3-methylglutaryl coenzyme A reductaseQ44058458
Effect of hyperhomocysteinemia on plasma or tissue adenosine levels and renal functionQ44123762
Regulation of endothelin-A receptor sensitivity by cyclic adenosine monophosphate in rat hepatic stellate cellsQ44151762
Increased serum homocysteine and sudden death resulting from coronary atherosclerosis with fibrous plaquesQ44212454
Hyperhomocysteinemia activates nuclear factor-kappaB in endothelial cells via oxidative stress.Q44664001
P433issue5
P304page(s)E1002-10
P577publication date2005-01-11
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleHyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors
P478volume288

Reverse relations

cites work (P2860)
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