Deregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophy in vivo.

scientific article published on May 2016

Deregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophy in vivo. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/ACEL.12460
P932PMC publication ID4933664
P698PubMed publication ID27133203

P50authorZhejun CaiQ40927807
P2093author name stringChen Chen
Lei Yang
Wei Gong
Li Ni
Dao Wen Wang
Ming-Hui Zou
Peihua Wang
Ben Ma
Quanlu Duan
P2860cites workXBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanismQ24298728
XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activationQ24304996
Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesisQ24337309
MicroRNA-214 Is Upregulated in Heart Failure Patients and Suppresses XBP1-Mediated Endothelial Cells AngiogenesisQ28115504
Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumorsQ28254136
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosisQ28275274
Transcriptional regulation of VEGFA by the endoplasmic reticulum stress transducer OASIS in ARPE-19 cellsQ28485361
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocationQ28510062
The study of ISO induced heart failure rat modelQ28572698
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Regulation of glucose homeostasis through a XBP-1-FoxO1 interactionQ28592129
Regulation of cardiac hypertrophy by intracellular signalling pathwaysQ29615166
Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature developmentQ30434991
Transcriptional regulation of VEGF-A by the unfolded protein response pathwayQ33539754
Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein responseQ33686864
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathwayQ33926690
Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.Q35025591
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.Q35041384
Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overloadQ35095396
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasisQ35419603
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac functionQ35895986
MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivoQ36286532
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.Q36330343
VEGF function in vascular pathogenesisQ36331954
In search of new therapeutic targets and strategies for heart failure: recent advances in basic scienceQ36364300
Targeting XBP-1 as a novel anti-cancer strategy.Q36544398
Response of the coronary vasculature to myocardial hypertrophyQ36558638
Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flowQ37176759
miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophyQ37274522
Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathwayQ37648367
XBP1: the last two decadesQ37649065
Biology of Endoplasmic Reticulum Stress in the HeartQ37808904
Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failureQ39904074
Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cellsQ40024663
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.Q40519913
X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas.Q41859494
Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failureQ42928039
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophyQ43110528
X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytesQ43156368
Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in ratsQ45863064
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overloadQ57396501
Remodelling of Cardiac Extracellular Matrix duringβ-adrenergic Stimulation: Upregulation of SPARC in the Myocardium of Adult Rats,Q60442048
Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic DysfunctionQ60686997
Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytesQ64377708
Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanismsQ73035986
miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1Q83034995
P433issue4
P921main subjectendotheliumQ111140
angiogenesisQ539568
P304page(s)625-633
P577publication date2016-05-01
P1433published inAging CellQ2221073
P1476titleDeregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophy in vivo
P478volume15

Reverse relations

cites work (P2860)
Q511541174PBA strongly attenuates endoplasmic reticulum stress, fibrosis, and mitochondrial apoptosis markers in cyclosporine treated human gingival fibroblasts.
Q92324411Broken heart: A matter of the endoplasmic reticulum stress bad management?
Q38785751Critical role of X-box binding protein 1 in NADPH oxidase 4-triggered cardiac hypertrophy is mediated by receptor interacting protein kinase 1.
Q57236093Ethyl Acetate Extract of cf. Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress
Q42677134IRE1α/XBP1s branch of UPR links HIF1α activation to mediate ANGII-dependent endothelial dysfunction under particulate matter (PM) 2.5 exposure
Q33653691Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease
Q39335880Role of Endoplasmic Reticulum Stress, Autophagy, and Inflammation in Cardiovascular Disease
Q89848670Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model
Q92166012Unfolded Protein Response as a Therapeutic Target in Cardiovascular Disease
Q41817053XBP1 splicing triggers miR-150 transfer from smooth muscle cells to endothelial cells via extracellular vesicles
Q40985672XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells

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