scholarly article | Q13442814 |
P50 | author | Ann-Hwee Lee | Q85270146 |
P2093 | author name string | Scot R Kimball | |
Jae-Seon So | |||
Sang-Hyun Min | |||
Sungyun Cho | |||
P2860 | cites work | The unfolded protein response: integrating stress signals through the stress sensor IRE1α | Q24293771 |
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress | Q28306995 | ||
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas | Q28505821 | ||
Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells | Q28513964 | ||
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
The mammalian unfolded protein response | Q29547400 | ||
Tripartite management of unfolded proteins in the endoplasmic reticulum | Q33941135 | ||
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis | Q34169287 | ||
Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response | Q34236755 | ||
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
IRE1α activation protects mice against acetaminophen-induced hepatotoxicity | Q35760821 | ||
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation | Q36418004 | ||
Endoplasmic reticulum stress sensing in the unfolded protein response | Q36626672 | ||
Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism. | Q36830383 | ||
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development | Q37100863 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability | Q37377347 | ||
New insights into translational regulation in the endoplasmic reticulum unfolded protein response | Q38005599 | ||
Getting RIDD of RNA: IRE1 in cell fate regulation | Q38198370 | ||
The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells. | Q38309617 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Identification of a consensus element recognized and cleaved by IRE1 alpha. | Q38343711 | ||
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress | Q42163338 | ||
Initiation of protein synthesis in a cell-free system prepared from rat hepatocytes. | Q45901355 | ||
Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1. | Q48134071 | ||
PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation. | Q51951390 | ||
PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. | Q52000258 | ||
GCN2 phosphorylation of eIF2alpha activates NF-kappaB in response to UV irradiation | Q80540867 | ||
P433 | issue | 16 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2761-2770 | |
P577 | publication date | 2015-06-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis | |
P478 | volume | 35 |
Q51038542 | 5,7,3',4'-Tetramethoxyflavone protects chondrocytes from ER stress-induced apoptosis through regulation of the IRE1α pathway. |
Q36483172 | An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response. |
Q42156227 | Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response |
Q28548490 | Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation |
Q35867141 | Endoplasmic Reticulum-Associated rht-PA Processing in CHO Cells: Influence of Mild Hypothermia and Specific Growth Rates in Batch and Chemostat Cultures |
Q38925531 | Endoplasmic reticulum proteostasis in hepatic steatosis. |
Q102220441 | Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α |
Q60909527 | Linking Endoplasmic Reticular Stress and Alternative Splicing |
Q52308796 | Preemptive activation of the integrated stress response protects mice from diet-induced obesity and insulin resistance via fibroblast growth factor 21 induction. |
Q47104159 | Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival. |
Q37282125 | Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. |
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