Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.

scientific article published in May 2017

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NCB3518
P932PMC publication ID5563826
P698PubMed publication ID28459443

P50authorBart LambrechtQ18402373
Gert Van IsterdaelQ42853542
Fabiola OsorioQ57339909
Nele VanlangenakkerQ81260251
Juan R Del ValleQ88395651
P2093author name stringRiet De Rycke
Eef Parthoens
Chih-Chi Andrew Hu
Takao Iwawaki
Sophie Janssens
Simon J Tavernier
Lianne van de Laar
Karl Vergote
Jessica Vetters
Lana Vandersarren
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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
Plasma cell differentiation requires the transcription factor XBP-1Q24291453
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
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Translational control is required for the unfolded protein response and in vivo glucose homeostasisQ28204066
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XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glandsQ28510479
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alphaQ28512201
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulumQ28512249
The transcription factor XBP-1 is essential for the development and survival of dendritic cellsQ28512302
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox stateQ28572472
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networksQ28591575
Regulation of glucose homeostasis through a XBP-1-FoxO1 interactionQ28592129
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An integrated stress response regulates amino acid metabolism and resistance to oxidative stressQ29547441
Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-beta induction via X-box binding protein 1.Q39620175
ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stressQ40006517
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosisQ42207479
Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergenQ43468956
A composite tissue‐engineered trachea using sheep nasal chondrocyte and epithelial cellsQ44425148
The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient miceQ44489907
A transgenic mouse model for monitoring endoplasmic reticulum stressQ44711192
Regulated IRE1-dependent decay participates in curtailing immunoglobulin secretion from plasma cellsQ45387412
Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow.Q47687570
Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo.Q50885261
IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.Q51002504
PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development.Q53316753
Maintaining dendritic cell viability in culture.Q54333739
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stressQ29615495
Translational control in stress and apoptosisQ29615497
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed settingQ29618424
Paneth cells as a site of origin for intestinal inflammation.Q30559414
Haematopoietic stem cells require a highly regulated protein synthesis rateQ33588717
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathwayQ33926690
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathwayQ33943895
Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection.Q34277045
The transcription factor XBP1 is selectively required for eosinophil differentiationQ34483620
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.Q34572339
CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cellsQ34734057
ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells.Q35168302
Genetic vaccines to potentiate the effective CD103+ dendritic cell-mediated cross-priming of antitumor immunity.Q35691240
IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein SynthesisQ35868391
Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational statusQ36063732
Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen.Q36229473
GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cellsQ36398839
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.Q36954378
Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunityQ36955782
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.Q37091581
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian developmentQ37100863
Examination of a second node of translational control in the unfolded protein responseQ37168900
Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and SpeciesQ37293474
Regulated Ire1-dependent decay of messenger RNAs in mammalian cellsQ37309146
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viabilityQ37377347
Cloning of Ly-5 cDNAQ37553735
L-Myc expression by dendritic cells is required for optimal T-cell primingQ37638439
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Getting RIDD of RNA: IRE1 in cell fate regulationQ38198370
IRF4 and IRF8 Act in CD11c+ Cells To Regulate Terminal Differentiation of Lung Tissue Dendritic CellsQ38275291
The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells.Q38309617
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.Q38311676
Proteostasis control by the unfolded protein responseQ38540196
Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survivalQ38996766
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.Q39299575
P433issue6
P921main subjectdendritic cellQ506253
P304page(s)698-710
P577publication date2017-05-01
P1433published inNature Cell BiologyQ1574111
P1476titleRegulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival
P478volume19

Reverse relations

cites work (P2860)
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Q41997586Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish

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