scholarly article | Q13442814 |
P50 | author | Xu Xu | Q88483439 |
P2093 | author name string | David E Cohen | |
Ann-Hwee Lee | |||
Jesper Gromada | |||
Jae-Seon So | |||
Curtis J Bare | |||
Christopher Krumm | |||
Corey Holman | |||
P2860 | cites work | FGF-21 as a novel metabolic regulator | Q24523933 |
Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor | Q45200756 | ||
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Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation. | Q51362717 | ||
Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency. | Q51597834 | ||
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine | Q63609769 | ||
ATF4 and the integrated stress response are induced by ethanol and cytochrome P450 2E1 in human hepatocytes | Q64380059 | ||
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis | Q81441036 | ||
Recombineering-based procedure for creating Cre/loxP conditional knockouts in the mouse | Q83240169 | ||
ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosis | Q84283864 | ||
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress | Q28306995 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells | Q28513964 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Fibroblast growth factor 21 is induced by endoplasmic reticulum stress | Q28581415 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
A highly efficient recombineering-based method for generating conditional knockout mutations | Q29615157 | ||
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states | Q29615208 | ||
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21 | Q29615209 | ||
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic | Q30525662 | ||
Stress-induced translation of ATF5 mRNA is regulated by the 5'-untranslated region | Q34720944 | ||
Fibroblast growth factor 21 corrects obesity in mice | Q34805555 | ||
The contribution of endoplasmic reticulum stress to liver diseases | Q34860549 | ||
DNA Damage Regulates Translation through β-TRCP Targeting of CReP | Q35668793 | ||
An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α. | Q35845921 | ||
IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis | Q35868391 | ||
Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet | Q36114917 | ||
An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response. | Q36483172 | ||
The transcription factor network associated with the amino acid response in mammalian cells | Q36830376 | ||
Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver. | Q36849447 | ||
Translational control and the unfolded protein response | Q36924278 | ||
CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis | Q37005595 | ||
Metabolic Responses to Dietary Protein Restriction Require an Increase in FGF21 that Is Delayed by the Absence of GCN2 | Q37116027 | ||
ATF4 protein deficiency protects against high fructose-induced hypertriglyceridemia in mice. | Q37132127 | ||
Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21. | Q37594100 | ||
FGF21-based pharmacotherapy--potential utility for metabolic disorders | Q38202720 | ||
Liver-specific Gene Inactivation of the Transcription Factor ATF4 Alleviates Alcoholic Liver Steatosis in Mice | Q38758523 | ||
FGF21-receptor agonists: an emerging therapeutic class for obesity-related diseases | Q39318225 | ||
The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR | Q39593058 | ||
Fasting induced up-regulation of activating transcription factor 5 in mouse liver | Q39859438 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism | Q41909224 | ||
Stress Signaling in the Methionine-Choline–Deficient Model of Murine Fatty Liver Disease | Q42391560 | ||
Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions | Q42523594 | ||
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice | Q43224118 | ||
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease | Q44934521 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | insulin resistance | Q1053470 |
P304 | page(s) | 2167-2181 | |
P577 | publication date | 2018-11-05 | |
P1433 | published in | Hepatology | Q15724398 |
P1476 | title | Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction | |
P478 | volume | 68 |
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Q92003593 | Effects of XIAP on high fat diet-induced hepatic steatosis: a mechanism involving NLRP3 inflammasome and oxidative stress |
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Q90025468 | Harnessing the Integrated Stress Response to Counteract Metabolic Disease |
Q92146409 | Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity |
Q93192737 | Metabolic remodeling induced by mitokines in heart failure |
Q101574061 | PPARα agonist and metformin co-treatment ameliorates NASH in mice induced by a choline-deficient, amino acid-defined diet with 45% fat |
Q58696918 | Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements |
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