| scholarly article | Q13442814 |
| P2093 | author name string | James P. Grenert | |
| Jacquelyn J. Maher | |||
| Russell K. Soon | |||
| Jim S. Yan | |||
| P2860 | cites work | Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase | Q22010589 |
| Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 | ||
| Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress | Q24291026 | ||
| TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death | Q24298384 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance | Q28244602 | ||
| CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription | Q28287446 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes | Q28506402 | ||
| PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
| Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
| Design and validation of a histological scoring system for nonalcoholic fatty liver disease | Q29614930 | ||
| Mediators of endoplasmic reticulum stress-induced apoptosis | Q29615496 | ||
| Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
| Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. | Q30488194 | ||
| Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins | Q33262919 | ||
| Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding | Q34524224 | ||
| The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane | Q34673029 | ||
| eIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver | Q35209983 | ||
| Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents | Q36183590 | ||
| Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet | Q36558384 | ||
| Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). | Q36561426 | ||
| Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Q36861224 | ||
| Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance | Q37038490 | ||
| GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
| Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis | Q37337488 | ||
| Mechanisms of clofibrate-induced apoptosis in Yoshida AH-130 hepatoma cells. | Q39921446 | ||
| Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
| Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). | Q40789492 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver | Q43194435 | ||
| Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice | Q44493750 | ||
| The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages | Q44542540 | ||
| Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury | Q44680230 | ||
| Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease | Q44934521 | ||
| The role of CHOP messenger RNA expression in the link between oxidative stress and apoptosis | Q46243190 | ||
| Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1. | Q46254429 | ||
| JNK1 but not JNK2 promotes the development of steatohepatitis in mice | Q46865809 | ||
| Quantitative trait loci analysis of mice administered the methionine-choline deficient dietary model of experimental steatohepatitis. | Q50716558 | ||
| Chop-deficient mice showed increased adiposity but no glucose intolerance. | Q51745940 | ||
| The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid. | Q53579178 | ||
| Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver | Q57016669 | ||
| Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1730-9, 1739.e1 | |
| P577 | publication date | 2010-08-01 | |
| P1433 | published in | Gastroenterology | Q4039279 |
| P1476 | title | Stress signaling in the methionine-choline-deficient model of murine fatty liver disease | |
| Stress Signaling in the Methionine-Choline–Deficient Model of Murine Fatty Liver Disease | |||
| P478 | volume | 139 |
| Q39726227 | C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis. |
| Q36967242 | C/EBP homologous protein-induced macrophage apoptosis protects mice from steatohepatitis |
| Q46606674 | CHOP-mediated hepcidin suppression modulates hepatic iron load. |
| Q35938040 | Cell death and cell death responses in liver disease: mechanisms and clinical relevance |
| Q36251478 | Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency |
| Q36695961 | Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression |
| Q58750358 | Complex Network of NKT Cell Subsets Controls Immune Homeostasis in Liver and Gut |
| Q28468698 | Defining hepatic dysfunction parameters in two models of fatty liver disease in zebrafish larvae |
| Q54291501 | Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition. |
| Q35490178 | Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis |
| Q42199386 | ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development |
| Q47103055 | FXR controls CHOP expression in steatohepatitis |
| Q36345406 | Hedgehog controls hepatic stellate cell fate by regulating metabolism |
| Q82798287 | Hepatic endoplasmic reticulum stress in obesity: deeper insights into processes, but are they relevant to nonalcoholic steatohepatitis? |
| Q37323927 | IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner |
| Q37726154 | Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. |
| Q37944211 | JNKs, insulin resistance and inflammation: A possible link between NAFLD and coronary artery disease |
| Q37070333 | Liver and diabetes. A vicious circle |
| Q35132916 | Mechanisms of lipotoxicity in NAFLD and clinical implications |
| Q35931190 | NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications. |
| Q92587283 | Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood |
| Q41583320 | Physiological/pathological ramifications of transcription factors in the unfolded protein response |
| Q52308796 | Preemptive activation of the integrated stress response protects mice from diet-induced obesity and insulin resistance via fibroblast growth factor 21 induction. |
| Q36114917 | Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet |
| Q36592437 | The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice |
| Q41864276 | Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease |
| Q38020432 | Traditional Chinese medicines benefit to nonalcoholic fatty liver disease: a systematic review and meta-analysis. |
| Q42592098 | Who pulls the trigger: JNK activation in liver lipotoxicity? |
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