| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/IUB.1224 |
| P698 | PubMed publication ID | 24227223 |
| P2093 | author name string | Claudio Hetz | |
| Víctor Hugo Cornejo | |||
| Philippe Pihán | |||
| René Luis Vidal | |||
| P2860 | cites work | Activation of the unfolded protein response enhances motor recovery after spinal cord injury | Q42143560 |
| Cell-nonautonomous control of the UPR. | Q42322674 | ||
| Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | Q42451739 | ||
| ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
| Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice | Q43076742 | ||
| Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH. | Q43106855 | ||
| AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease | Q45306832 | ||
| Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 | ||
| CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury | Q46823993 | ||
| Chop-deficient mice showed increased adiposity but no glucose intolerance. | Q51745940 | ||
| PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation. | Q51951390 | ||
| Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres. | Q52178375 | ||
| Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice. | Q52545083 | ||
| Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance. | Q53181684 | ||
| ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis | Q57267073 | ||
| Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 | ||
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expression | Q24291231 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
| Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response | Q24304232 | ||
| Atf4 regulates obesity, glucose homeostasis, and energy expenditure | Q24648259 | ||
| XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy | Q24655821 | ||
| XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells | Q24658399 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis | Q27313877 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter | Q28119099 | ||
| Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis | Q28258427 | ||
| Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
| Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice | Q28359871 | ||
| The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas | Q28505821 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes | Q28506402 | ||
| Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 | Q28507338 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2 | Q42094437 | ||
| The transcription factor XBP-1 is essential for the development and survival of dendritic cells | Q28512302 | ||
| CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism | Q28579022 | ||
| OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes | Q28580776 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA | Q28587767 | ||
| Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation | Q28587852 | ||
| Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis | Q28591480 | ||
| XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
| Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
| Gene-specific regulation by general translation factors | Q28611181 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
| Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress | Q29615495 | ||
| Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility. | Q30465575 | ||
| Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. | Q30488194 | ||
| Increased intestinal lipid absorption caused by Ire1β deficiency contributes to hyperlipidemia and atherosclerosis in apolipoprotein E-deficient mice. | Q30518782 | ||
| Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits | Q30543820 | ||
| PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice | Q30945763 | ||
| PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice | Q33295459 | ||
| The ER stress transducer IRE1β is required for airway epithelial mucin production | Q33652759 | ||
| IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level | Q33707431 | ||
| Regulation of basal cellular physiology by the homeostatic unfolded protein response | Q33886820 | ||
| Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway | Q33943895 | ||
| C/EBP homologous protein (CHOP) deficiency aggravates hippocampal cell apoptosis and impairs memory performance | Q34345215 | ||
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
| Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding | Q34524224 | ||
| PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites | Q34541337 | ||
| The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex | Q34673344 | ||
| Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. | Q34820742 | ||
| Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
| IRE1α activation protects mice against acetaminophen-induced hepatotoxicity | Q35760821 | ||
| Deletion of the pro-apoptotic endoplasmic reticulum stress response effector CHOP does not result in improved locomotor function after severe contusive spinal cord injury | Q35764147 | ||
| The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis | Q35830099 | ||
| Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice | Q35870151 | ||
| Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy | Q35909430 | ||
| Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation | Q35986635 | ||
| Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
| Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. | Q36393034 | ||
| XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells | Q36402768 | ||
| PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis | Q36435206 | ||
| Negative feedback by IRE1β optimizes mucin production in goblet cells | Q36637632 | ||
| ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo | Q36640055 | ||
| ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice | Q36709748 | ||
| Activating transcription factor 4. | Q36805075 | ||
| Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis | Q36845177 | ||
| Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Q36861224 | ||
| X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function | Q37015048 | ||
| IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Q37091581 | ||
| Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments | Q37124391 | ||
| ATF4 protein deficiency protects against high fructose-induced hypertriglyceridemia in mice. | Q37132127 | ||
| Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
| The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts | Q37328439 | ||
| Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells | Q37343526 | ||
| Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability | Q37377347 | ||
| XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development | Q37377432 | ||
| Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. | Q37429758 | ||
| PERK in beta cell biology and insulin biogenesis | Q37789918 | ||
| Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factors | Q37857795 | ||
| Targeting the unfolded protein response in disease. | Q38132652 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1. | Q38360645 | ||
| XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity | Q38681055 | ||
| ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1. | Q38947838 | ||
| IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. | Q39422225 | ||
| XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum | Q39659690 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
| The ER stress pathway involving CHOP is activated in the lungs of LPS-treated mice | Q40354362 | ||
| Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. | Q41087457 | ||
| P433 | issue | 12 | |
| P921 | main subject | physiology | Q521 |
| P304 | page(s) | 962-975 | |
| P577 | publication date | 2013-11-13 | |
| P1433 | published in | IUBMB Life | Q15764029 |
| P1476 | title | Role of the unfolded protein response in organ physiology: lessons from mouse models. | |
| P478 | volume | 65 |
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| Q36610939 | Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury |
| Q38241810 | Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview. |
| Q28509073 | Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1 |
| Q38195215 | Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases |
| Q40070040 | ER Stress and Neurodegenerative Disease: A Cause or Effect Relationship? |
| Q38653861 | ER stress and the unfolded protein response in neurodegeneration |
| Q45874593 | Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease |
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