| scholarly article | Q13442814 |
| P356 | DOI | 10.2337/DB12-1747 |
| P8608 | Fatcat ID | release_hlb2eoibanhhrcxmja4sraboci |
| P932 | PMC publication ID | 3712068 |
| P698 | PubMed publication ID | 23493568 |
| P5875 | ResearchGate publication ID | 236048023 |
| P50 | author | Robert T. Kennedy | Q37377296 |
| P2093 | author name string | Chong Wee Liew | |
| Rohit N Kulkarni | |||
| Jiang Hu | |||
| Masaru Akiyama | |||
| Rachael Martinez | |||
| Shusheng Lu | |||
| Ben Hambro | |||
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
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| Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea | Q57214866 | ||
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| Immunohistochemical and ultrastructural study of adult porcine endocrine pancreas during the different steps of islet isolation | Q71848699 | ||
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| The Role of Glucagon in the Endogenous Hyperglycemia of Diabetes Mellitus | Q39622363 | ||
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| Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells. | Q40416559 | ||
| Normalization of fasting hyperglucagonemia and excessive glucagon responses to intravenous arginine in human diabetes mellitus by prolonged infusion of insulin | Q42448743 | ||
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| Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3. | Q44909452 | ||
| Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 | ||
| Abnormal response of pancreatic glucagon to glycemic changes in diabetes mellitus | Q51665235 | ||
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Upstream and downstream of mTOR | Q28277365 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
| The mammalian unfolded protein response | Q29547400 | ||
| A central role for JNK in obesity and insulin resistance | Q29619778 | ||
| The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
| The cumate gene-switch: a system for regulated expression in mammalian cells | Q33262655 | ||
| The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. | Q33300966 | ||
| Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line | Q33848718 | ||
| The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells. | Q34028623 | ||
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
| Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels | Q34453916 | ||
| FoxO1 is required for the regulation of preproglucagon gene expression by insulin in pancreatic alphaTC1-9 cells | Q34576322 | ||
| Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
| Studies of pancreatic alpha cell function in normal and diabetic subjects | Q35576866 | ||
| Glucose- and hormone-induced cAMP oscillations in α- and β-cells within intact pancreatic islets | Q35797008 | ||
| XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
| Glucolipotoxicity: fuel excess and beta-cell dysfunction. | Q36861036 | ||
| The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes | Q36861041 | ||
| The role for endoplasmic reticulum stress in diabetes mellitus | Q37019672 | ||
| Insulin signaling in alpha cells modulates glucagon secretion in vivo | Q37223046 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported | Q19125045 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | preproinsulin | Q7240673 |
| cell function | Q95674809 | ||
| P1104 | number of pages | 11 | |
| P304 | page(s) | 2439-2449 | |
| P577 | publication date | 2013-03-14 | |
| P1433 | published in | Diabetes | Q895262 |
| P1476 | title | X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function | |
| P478 | volume | 62 |
| Q38241810 | Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview. |
| Q35196985 | Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy |
| Q57243233 | Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications |
| Q64941368 | Exendin-4 protects INS-1 cells against palmitate-induced apoptosis through the IRE1α-Xbp1 signaling pathway. |
| Q91330151 | Fast, sensitive and accurate integration of single-cell data with Harmony |
| Q33585517 | Glucotoxicity induces abnormal glucagon secretion through impaired insulin signaling in InR1G cells |
| Q61512382 | Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress |
| Q92255602 | Herpesviruses and the Unfolded Protein Response |
| Q42415245 | High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice |
| Q37063923 | IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation. |
| Q37597046 | Insulin resistance alters islet morphology in nondiabetic humans |
| Q27015015 | Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases |
| Q33858456 | JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway |
| Q98778489 | Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas |
| Q35003800 | Obesity promotes alterations in iron recycling |
| Q35799671 | Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes |
| Q36837405 | Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes |
| Q54397189 | Role of the unfolded protein response in organ physiology: lessons from mouse models. |
| Q47099163 | Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function. |
| Q89965069 | Stathmin-2 Mediates Glucagon Secretion From Pancreatic α-Cells |
| Q64084909 | The Involvement of Renin-Angiotensin System in Lipopolysaccharide-Induced Behavioral Changes, Neuroinflammation, and Disturbed Insulin Signaling |
| Q37319994 | The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions |
| Q38211528 | The regulation of pre- and post-maturational plasticity of mammalian islet cell mass. |
| Q42835425 | X-box binding protein 1 is a novel key regulator of peroxisome proliferator-activated receptor γ2. |
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