Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

scientific journal article

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1 is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PNAS..111.6804V
P356DOI10.1073/PNAS.1321845111
P932PMC publication ID4020088
P698PubMed publication ID24753614
P5875ResearchGate publication ID261772411

P50authorBernard L. SchneiderQ37377455
Danny GalleguillosQ39957300
P2093author name stringClaudio Hetz
Felipe A Court
Gabriela Mercado
Claudia Molina
Rene L Vidal
Pamela Valdés
Donna Armentano
Alexis Martinez
Geoffrey Parsons
P2860cites workXBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
The unfolded protein response: integrating stress signals through the stress sensor IRE1αQ24293771
Protective effect against Parkinson's disease-related insults through the activation of XBP1Q24314837
Homocysteine-induced endoplasmic reticulum protein (herp) is up-regulated in parkinsonian substantia nigra and present in the core of Lewy bodiesQ24319400
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagyQ24655821
Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neuronsQ40669010
Scaleable chromatographic purification process for recombinant adeno-associated virus (rAAV).Q40825421
The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal deathQ41767754
Transmissible proteins: expanding the prion heresyQ42080116
Activation of the unfolded protein response enhances motor recovery after spinal cord injuryQ42143560
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.Q44251931
AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's diseaseQ45306832
Activation of the unfolded protein response in Parkinson's diseaseQ48297659
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synucleinQ48581887
Role of the unfolded protein response in organ physiology: lessons from mouse models.Q54397189
Cardioprotection by endoplasmic reticulum stress-induced autophagyQ84778523
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein responseQ24672592
When ER stress reaches a dead endQ26998580
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonismQ28579022
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
Autophagy and the Integrated Stress ResponseQ29547398
Parkinson's disease: mechanisms and modelsQ29547424
Epidemiology of Parkinson's diseaseQ29614901
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stressQ29615495
The unfolded protein response: controlling cell fate decisions under ER stress and beyondQ29615499
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteinsQ33262919
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neuronsQ33616462
Recent advances in the genetics of Parkinson's diseaseQ34189660
Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response MachineryQ34190184
ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson's diseaseQ34462449
Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1.Q34575640
Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signalingQ35858131
Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagyQ35909430
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.Q36000128
The impact of the unfolded protein response on human diseaseQ36062081
ER stress inhibits neuronal death by promoting autophagyQ36187772
Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivoQ36289970
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.Q36393034
Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.Q36543608
ER stress protects from retinal degenerationQ37194635
Mitophagy: the latest problem for Parkinson's diseaseQ37819135
Mitochondria, calcium, and endoplasmic reticulum stress in Parkinson's diseaseQ37889815
Endoplasmic reticulum dysfunction in neurological diseaseQ38067205
An ERcentric view of Parkinson's diseaseQ38076982
Targeting the unfolded protein response in disease.Q38132652
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseasesQ38195215
Hormesis: protecting neurons against cellular stress in Parkinson diseaseQ39575131
Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathologyQ40518177
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
X-box binding protein 1Q21992827
dopaminergic neuronQ66591220
P304page(s)6804-6809
P577publication date2014-04-21
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleControl of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
P478volume111

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