review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1048097684 |
P356 | DOI | 10.1186/1750-1326-9-35 |
P932 | PMC publication ID | 4166022 |
P698 | PubMed publication ID | 25216759 |
P5875 | ResearchGate publication ID | 265607272 |
P50 | author | Eric Duplan | Q38321066 |
Frédéric Checler | Q38321085 | ||
P2093 | author name string | Julie Dunys | |
P2860 | cites work | XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 |
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase | Q22254584 | ||
Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response | Q24305069 | ||
Protective effect against Parkinson's disease-related insults through the activation of XBP1 | Q24314837 | ||
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism | Q24321359 | ||
The ER stress factor XBP1s prevents amyloid-beta neurotoxicity | Q24598012 | ||
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy | Q24655821 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. | Q27860836 | ||
S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease | Q28116512 | ||
A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter | Q28119099 | ||
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response | Q28139601 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration | Q28242222 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1 | Q28509073 | ||
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation | Q28510062 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response | Q28589998 | ||
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction | Q28592129 | ||
An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
The unfolded protein response: controlling cell fate decisions under ER stress and beyond | Q29615499 | ||
Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice | Q30494698 | ||
Identification of an expanded CAG repeat in the Huntington's disease gene (IT15) in a family reported to have benign hereditary chorea | Q33596088 | ||
The cellular response to protein misfolding in the endoplasmic reticulum. | Q33706901 | ||
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway | Q33926690 | ||
IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux | Q34033567 | ||
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. | Q34189618 | ||
The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response | Q35170906 | ||
Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy | Q35909430 | ||
XBP1 activates the transcription of its target genes via an ACGT core sequence under ER stress. | Q53676823 | ||
Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice. | Q54328614 | ||
Mechanisms underlying hypertriglyceridemia in rats with monosodium L-glutamate-induced obesity: evidence of XBP-1/PDI/MTP axis activation. | Q54447692 | ||
Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo | Q83323941 | ||
The other sweet face of XBP-1 | Q83557676 | ||
Differential activation of the ER stress factor XBP1 by oligomeric assemblies | Q36070065 | ||
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis | Q36600595 | ||
XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells | Q36739979 | ||
The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus | Q37164517 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Activation and clinical significance of the unfolded protein response in breast cancer | Q37424111 | ||
The role of X-box binding protein-1 in tumorigenicity. | Q37553966 | ||
p53 in neurodegenerative diseases and brain cancers | Q38167220 | ||
Lipid landscapes and pipelines in membrane homeostasis | Q38217765 | ||
Human HRD1 promoter carries a functional unfolded protein response element to which XBP1 but not ATF6 directly binds | Q38288841 | ||
Targeted disruption of CRE-binding factor TREB5 gene leads to cellular necrosis in cardiac myocytes at the embryonic stage | Q38322371 | ||
IRE1alpha controls cyclin A1 expression and promotes cell proliferation through XBP-1. | Q38347956 | ||
Overexpression of human X-box binding protein 1 (XBP-1) in colorectal adenomas and adenocarcinomas. | Q38433525 | ||
Upregulation and overexpression of human X-box binding protein 1 (hXBP-1) gene in primary breast cancers | Q38449959 | ||
Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival | Q38996766 | ||
Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease. | Q39069488 | ||
ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1. | Q39187400 | ||
TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes | Q39306114 | ||
Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation | Q39726471 | ||
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis | Q39843795 | ||
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. | Q40254780 | ||
Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease | Q40414917 | ||
The natural history of motoneuron loss in amyotrophic lateral sclerosis | Q41434654 | ||
Splicing: HACking into the unfolded-protein response | Q41720776 | ||
Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity | Q42042260 | ||
Polymorphism -116C/G of human X-box-binding protein 1 promoter is associated with risk of Alzheimer's disease | Q43574936 | ||
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. | Q44251931 | ||
CAG repeat size and clinical presentation in Huntington's disease | Q45290140 | ||
AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease | Q45306832 | ||
Activation of the unfolded protein response in Parkinson's disease | Q48297659 | ||
The unfolded protein response is activated in Alzheimer's disease. | Q48839954 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | transcription factor | Q407384 |
regulation of gene expression | Q411391 | ||
neurodegeneration | Q1755122 | ||
DNA-binding protein | Q2252764 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 35 | |
P577 | publication date | 2014-09-12 | |
P1433 | published in | Molecular Neurodegeneration | Q15817329 |
P1476 | title | The transcription factor X-box binding protein-1 in neurodegenerative diseases | |
P478 | volume | 9 |
Q47831348 | Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer's Disease Treatment. |
Q47596098 | Are sigma receptor modulators a weapon against multiple sclerosis disease? |
Q48211267 | Association of the AURKA and AURKC gene polymorphisms with an increased risk of gastric cancer |
Q42053390 | Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1. |
Q27022552 | Diabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stress |
Q47098483 | Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer |
Q38713406 | High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-reticulum-stress. |
Q38463463 | Molecular mechanisms of diabetic retinopathy: potential therapeutic targets |
Q88442029 | Neurodegenerative diseases have genetic hallmarks of autoinflammatory disease |
Q90435275 | Rotavirus Infection Alters Splicing of the Stress-Related Transcription Factor XBP1 |
Q36887309 | The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease. |
Q41828232 | The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease |
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