Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1.

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Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1. is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.199729
P932PMC publication ID3039327
P698PubMed publication ID21138840

P2093author name stringSarah X Zhang
Joshua J Wang
Jingming Li
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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
IRE1 signaling affects cell fate during the unfolded protein responseQ29615502
Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient miceQ30304058
Pharmacological approach to diabetic retinopathy.Q33200037
Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathyQ33303988
Association of vitreous inflammatory factors with diabetic macular edemaQ33396882
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Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expressionQ34563098
Differential roles of ICAM-1 and VCAM-1 in leukocyte-endothelial cell interactions in skin and brain of MRL/faslpr miceQ35227677
Epidemiology of proliferative diabetic retinopathyQ35594913
Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid.Q35798412
Preconditioning with endoplasmic reticulum stress ameliorates mesangioproliferative glomerulonephritisQ36662140
Contributions of inflammatory processes to the development of the early stages of diabetic retinopathyQ37084522
Immunological mechanisms in the pathogenesis of diabetic retinopathyQ37109989
Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathyQ37214899
Novel potential mechanisms for diabetic macular edema: leveraging new investigational approachesQ37217856
The endoplasmic reticulum stress response in immunity and autoimmunityQ37231726
Genetic difference in susceptibility to the blood-retina barrier breakdown in diabetes and oxygen-induced retinopathyQ38585087
Acquisition of anergy to proinflammatory cytokines in nonimmune cells through endoplasmic reticulum stress response: a mechanism for subsidence of inflammationQ39898399
Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell linesQ40148265
Protection of Renal Epithelial Cells against Oxidative Injury by Endoplasmic Reticulum Stress Preconditioning Is Mediated by ERK1/2 ActivationQ40648961
Vascular endothelial growth factor in ocular neovascularization and proliferative diabetic retinopathy.Q41457787
Systemic administration of HMG-CoA reductase inhibitor protects the blood-retinal barrier and ameliorates retinal inflammation in type 2 diabetesQ41810320
TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterationsQ42592010
Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathyQ43160577
Quantitative assessment of the integrity of the blood-retinal barrier in miceQ44046031
The role of adhesion molecules (ICAM-1 and E-selectin) in development of diabetic microangiopathiesQ44075919
A central role for inflammation in the pathogenesis of diabetic retinopathyQ44961996
SAR study of a novel triene-ansamycin group compound, quinotrierixin, and related compounds, as inhibitors of ER stress-induced XBP1 activationQ46463468
Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalphaQ46656235
Systemic and periocular deliveries of plasminogen kringle 5 reduce vascular leakage in rat models of oxygen-induced retinopathy and diabetesQ46658213
Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling.Q46886403
Blunted activation of NF-kappaB and NF-kappaB-dependent gene expression by geranylgeranylacetone: involvement of unfolded protein response.Q46923208
Macular and peripheral distribution of ICAM-1 in the human choriocapillaris and retinaQ58547926
Activated T lymphocytes in epiretinal membranes from eyes of patients with proliferative diabetic retinopathyQ72165945
The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XV. The long-term incidence of macular edemaQ72432533
Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetesQ80510725
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
inflammationQ101991
endotheliumQ111140
P304page(s)4912-4921
P577publication date2010-12-07
P1433published inJournal of Biological ChemistryQ867727
P1476titlePreconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1.
P478volume286

Reverse relations

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