| scholarly article | Q13442814 |
| P50 | author | Megan E. Capozzi | Q56998851 |
| P2093 | author name string | Gary W McCollum | |
| John S Penn | |||
| Sandra S Hammer | |||
| P2860 | cites work | Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications | Q24616753 |
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| Soluble epoxide hydrolase inhibition modulates vascular remodeling | Q28394250 | ||
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| The biological actions of 11,12-epoxyeicosatrienoic acid in endothelial cells are specific to the R/S-enantiomer and require the G(s) protein | Q33773518 | ||
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| The role of cytochrome P450 epoxygenases in retinal angiogenesis | Q33901500 | ||
| Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy | Q33930304 | ||
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| A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity | Q34000354 | ||
| Endogenous epoxygenases are modulators of monocyte/macrophage activity | Q34058704 | ||
| The antiinflammatory effect of laminar flow: the role of PPARgamma, epoxyeicosatrienoic acids, and soluble epoxide hydrolase | Q34116662 | ||
| Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids | Q34287840 | ||
| The factor in EDHF: Cytochrome P450 derived lipid mediators and vascular signaling. | Q34518126 | ||
| Diabetic Retinopathy | Q57232741 | ||
| DiscrEET regulators of homeostasis: epoxyeicosatrienoic acids, cytochrome P450 epoxygenases and vascular inflammation | Q60760045 | ||
| Arachidonic acid metabolism by retinas of rats with streptozotocin-induced diabetes | Q70501562 | ||
| Docosahexaenoic acid is a major n-3 polyunsaturated fatty acid in bovine retinal microvessels | Q71464628 | ||
| Serum factor from diabetic patients with or without retinopathy stimulates superoxide anion production by normal polymorphonuclear leukocytes | Q71662882 | ||
| Integrin-mediated neutrophil adhesion and retinal leukostasis in diabetes | Q73640405 | ||
| Diabetic retinopathy | Q75217418 | ||
| Increased vasodilatory prostaglandin production in the diabetic rat retinal vasculature | Q77387245 | ||
| Mechanisms of selective leukocyte recruitment from whole blood on cytokine-activated endothelial cells under flow conditions | Q77404936 | ||
| Comparison of serum NO, TNF-alpha, IL-1beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus | Q78040840 | ||
| Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy | Q81473347 | ||
| Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension | Q82272822 | ||
| Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects | Q83663079 | ||
| Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels | Q83986866 | ||
| Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization | Q34527211 | ||
| Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1. | Q34575640 | ||
| 12/15-Lipoxygenase-derived lipid metabolites induce retinal endothelial cell barrier dysfunction: contribution of NADPH oxidase | Q34600290 | ||
| Modulation of VEGF-induced retinal vascular permeability by peroxisome proliferator-activated receptor-β/δ. | Q34741796 | ||
| TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis | Q35005977 | ||
| Overexpression of G-protein-coupled receptor 40 enhances the mitogenic response to epoxyeicosatrienoic acids | Q35094877 | ||
| A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase. | Q35120919 | ||
| EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells | Q35649907 | ||
| Epoxyeicosatrienoic acids regulate macrophage polarization and prevent LPS-induced cardiac dysfunction | Q35742804 | ||
| Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo | Q35829191 | ||
| Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid | Q35989359 | ||
| Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo | Q36445448 | ||
| Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia | Q36625899 | ||
| Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis | Q36782159 | ||
| Immunological mechanisms in the pathogenesis of diabetic retinopathy | Q37109989 | ||
| CYP450-derived oxylipins mediate inflammatory resolution. | Q37183722 | ||
| Transcriptional regulation of the human soluble epoxide hydrolase gene EPHX2 | Q37236533 | ||
| Müller glia cells regulate Notch signaling and retinal angiogenesis via the generation of 19,20-dihydroxydocosapentaenoic acid. | Q37576699 | ||
| Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells. | Q37709772 | ||
| Inflammation in diabetic retinopathy | Q37884176 | ||
| Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-alpha | Q38339357 | ||
| Serum inflammatory cytokines IL-1beta, IL-6, TNF-alpha and VEGF have influence on the development of diabetic retinopathy. | Q39723909 | ||
| 11,12-epoxyeicosatrienoic acid attenuates synthesis of prostaglandin E2 in rat monocytes stimulated with lipopolysaccharide | Q40553922 | ||
| Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues | Q40575921 | ||
| Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition | Q40816487 | ||
| Epoxyeicosanoid Signaling Provides Multi-target Protective Effects on Neurovascular Unit in Rats After Focal Ischemia | Q40919308 | ||
| Diabetic retinopathy and inflammation: novel therapeutic targets. | Q41012046 | ||
| Role of inflammation in the pathogenesis of diabetic retinopathy | Q41012127 | ||
| PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells | Q42267879 | ||
| NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis. | Q43191572 | ||
| Structural refinement of inhibitors of urea-based soluble epoxide hydrolases | Q43990736 | ||
| Cytochrome p-450 epoxygenase metabolites of docosahexaenoate potently dilate coronary arterioles by activating large-conductance calcium-activated potassium channels | Q44186101 | ||
| Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model | Q44264318 | ||
| Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation | Q44328998 | ||
| Dyslipidemia, but Not Hyperglycemia, Induces Inflammatory Adhesion Molecules in Human Retinal Vascular Endothelial Cells | Q44632017 | ||
| 11,12-epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression | Q44638682 | ||
| A central role for inflammation in the pathogenesis of diabetic retinopathy | Q44961996 | ||
| Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats | Q45042343 | ||
| Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors | Q46410871 | ||
| Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways | Q46446028 | ||
| Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids | Q46939863 | ||
| Homocysteine and diabetic retinopathy | Q46980069 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | fatty acid | Q61476 |
| inflammation | Q101991 | ||
| P304 | page(s) | 39211 | |
| P577 | publication date | 2016-12-14 | |
| P1433 | published in | Scientific Reports | Q2261792 |
| P1476 | title | Epoxygenated Fatty Acids Inhibit Retinal Vascular Inflammation | |
| P478 | volume | 6 |
| Q94948624 | Association of Arachidonic Acid-derived Lipid Mediators with Subsequent Onset of Acute Myocardial Infarction in Patients with Coronary Artery Disease |
| Q46028902 | Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling. |
| Q50175494 | Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target. |
| Q92105332 | New Lipid Mediators in Retinal Angiogenesis and Retinopathy |
| Q64241468 | Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future |
| Q93073795 | Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity |
| Q38762998 | The role of dyslipidemia in diabetic retinopathy |
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