Immunological mechanisms in the pathogenesis of diabetic retinopathy

scientific article published on 14 March 2008

Immunological mechanisms in the pathogenesis of diabetic retinopathy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00281-008-0111-X
P698PubMed publication ID18340447

P2093author name stringAnthony P Adamis
Adrienne J Berman
P2860cites workMigration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1Q24323317
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CD4-CD8 and CD28 expression in T cells infiltrating the vitreous fluid in patients with proliferative diabetic retinopathy: a flow cytometric analysis.Q47623063
Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.Q47681650
Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1.Q48024877
A prize catch for diabetic retinopathyQ48331968
Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage.Q50464660
Glial reactivity, an early feature of diabetic retinopathy.Q50511477
Expression of CD18 on the neutrophils of patients with diabetic retinopathy.Q53610983
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[TNF-alpha level in the vitreous body. Increase in neovascular eye diseases and proliferative diabetic retinopathy]Q72173190
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Catalogue of soluble proteins in human vitreous humor by one-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis and electrospray ionization mass spectrometry including seven angiogenesis-regulating factorsQ73580396
The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularizationQ73587530
Integrin-mediated neutrophil adhesion and retinal leukostasis in diabetesQ73640405
Intracellular pool of vascular endothelial growth factor in human neutrophilsQ73838822
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DIABETIC RETINOPATHY AND RHEUMATOID ARTHRITISQ76819514
Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structuresQ78570627
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Erythropoietin is expressed in the human retina and it is highly elevated in the vitreous fluid of patients with diabetic macular edemaQ80175166
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Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathyQ81473347
Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alphaQ81512331
Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetesQ82097295
Platelets accumulate in the diabetic retinal vasculature following endothelial death and suppress blood-retinal barrier breakdownQ35791582
Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid.Q35798412
Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by intercellular adhesion molecule-1 (ICAM-1).Q35810089
Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage.Q35885116
Tumour necrosis factor alpha as a therapeutic target for immune-mediated inflammatory diseasesQ35961215
Inhibitors of ocular neovascularization: promises and potential problems.Q36077697
Neutrophil-derived cytokines: potential therapeutic targets in inflammation.Q36230445
Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctionsQ36237571
Hereditary angioedemaQ36282895
VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization.Q36371399
Intravitreal triamcinolone acetonide: a change in a paradigmQ36500994
Intravitreal injection of bevacizumab (Avastin) as adjunctive treatment of proliferative diabetic retinopathyQ36608675
Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degenerationQ36619213
The role of TNF-alpha in diabetic nephropathy: pathogenic and therapeutic implicationsQ36657215
Clinical pharmacokinetics and use of infliximabQ36892770
Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cellsQ37101882
Distribution of TNF alpha and its reactive vascular adhesion molecules in fibrovascular membranes of proliferative diabetic retinopathyQ37318352
Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathyQ37356613
Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivoQ37360588
Advanced glycation end products increase retinal vascular endothelial growth factor expressionQ37379211
Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulinQ37384532
Macrophages in proliferative vitreoretinopathy and proliferative diabetic retinopathy: differentiation of subpopulationsQ39697208
Vascular endothelial growth factor reduced and connective tissue growth factor induced by triamcinolone in ARPE19 cells under oxidative stress.Q40454968
VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.Q40595312
Modulation of permeability and adhesion molecule expression by human choroidal endothelial cells.Q40707728
Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relationQ40937602
Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis.Q41295542
Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migrationQ41711674
Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factorQ42503628
Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathyQ42756254
Angiopoietin concentrations in diabetic retinopathyQ43007236
Increased prevalence of microthromboses in retinal capillaries of diabetic individualsQ43618953
VEGF-initiated blood-retinal barrier breakdown in early diabetes.Q43723423
In vivo retinal gene expression in early diabetes.Q43785508
Extensive deposits of complement C3d and C5b-9 in the choriocapillaris of eyes of patients with diabetic retinopathyQ43940024
Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with diabetic macular edema and other retinal disordersQ43946490
Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathyQ44230956
Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetesQ44244855
Immunocytochemical localization of vascular endothelial growth factor in neurons and glial cells of human retinaQ44390940
VEGF164Is Proinflammatory in the Diabetic RetinaQ44417311
Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in diseaseQ44429660
Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edemaQ44586436
P433issue2
P921main subjectpathogenesisQ372016
P304page(s)65-84
P577publication date2008-03-14
P1433published inSeminars in ImmunopathologyQ15724576
P1476titleImmunological mechanisms in the pathogenesis of diabetic retinopathy
P478volume30

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