| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Wayne I. Lencer | Q38328140 |
| P2093 | author name string | Jin Ah Cho | |
| Michael J Grey | |||
| Heidi DeLuca | |||
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress | Q24290818 | ||
| Peroxisomes are signaling platforms for antiviral innate immunity | Q24310723 | ||
| Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
| Structure, function and diversity of the healthy human microbiome | Q24626370 | ||
| Emerging functions of the unfolded protein response in immunity | Q26827965 | ||
| The unfolded protein response signals through high-order assembly of Ire1 | Q27653139 | ||
| Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1 | Q27660827 | ||
| Structural and functional basis for RNA cleavage by Ire1 | Q27670676 | ||
| Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1 | Q27670678 | ||
| Innate immune recognition | Q27860721 | ||
| RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates | Q27861007 | ||
| Host-bacterial mutualism in the human intestine | Q27861037 | ||
| A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
| Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins | Q27932183 | ||
| Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention | Q41829978 | ||
| A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. | Q41854293 | ||
| RIG-I "sees" the 5'-triphosphate | Q41966734 | ||
| Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins | Q50336381 | ||
| RNase domains determine the functional difference between IRE1alpha and IRE1beta. | Q50336397 | ||
| AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. | Q53595113 | ||
| A hybrid protein kinase-RNase in an interferon-induced pathway? | Q56918740 | ||
| Genetic control of the murine immune response to cholera toxin | Q69950633 | ||
| Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin | Q72815583 | ||
| The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
| Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
| 5'-Triphosphate RNA is the ligand for RIG-I | Q28131726 | ||
| Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast | Q28140422 | ||
| The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 | Q28185796 | ||
| Plant pathogens and integrated defence responses to infection | Q28207107 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Structural basis of the unfolded protein response | Q28276836 | ||
| Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice | Q28359871 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Cloning of mammalian Ire1 reveals diversity in the ER stress responses | Q28587224 | ||
| Worlds within worlds: evolution of the vertebrate gut microbiota | Q28754891 | ||
| Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| Decoding the patterns of self and nonself by the innate immune system | Q29618448 | ||
| Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering | Q30496639 | ||
| Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways | Q33330462 | ||
| The ER stress transducer IRE1β is required for airway epithelial mucin production | Q33652759 | ||
| An essential role for XBP-1 in host protection against immune activation in C. elegans | Q33710158 | ||
| Regulation of basal cellular physiology by the homeostatic unfolded protein response | Q33886820 | ||
| Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway | Q33891036 | ||
| Immune responses to the microbiota at the intestinal mucosal surface | Q34019457 | ||
| The SKIV2L RNA exosome limits activation of the RIG-I-like receptors | Q34071054 | ||
| The unfolded protein response triggers selective mRNA release from the endoplasmic reticulum | Q34175060 | ||
| On the mechanism of sensing unfolded protein in the endoplasmic reticulum | Q34230593 | ||
| Direct association of unfolded proteins with mammalian ER stress sensor, IRE1β | Q34510834 | ||
| Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
| Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. | Q34572339 | ||
| Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum | Q34590456 | ||
| Messenger RNA targeting to endoplasmic reticulum stress signalling sites. | Q34903088 | ||
| Cytomegalovirus downregulates IRE1 to repress the unfolded protein response | Q34945470 | ||
| Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
| The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response | Q35029280 | ||
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
| Vibrio cholerae O1 infection induces proinflammatory CD4+ T-cell responses in blood and intestinal mucosa of infected humans | Q35138715 | ||
| Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Q38845249 | ||
| Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome | Q38985852 | ||
| Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome | Q39299566 | ||
| IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. | Q39299575 | ||
| IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. | Q39422225 | ||
| Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production | Q39774272 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity | Q39821844 | ||
| Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B. | Q39869036 | ||
| Small self-RNA generated by RNase L amplifies antiviral innate immunity | Q40180990 | ||
| Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD. | Q41585784 | ||
| Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus | Q35197999 | ||
| Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
| Endoplasmic reticulum stress sensing in the unfolded protein response | Q36626672 | ||
| Negative feedback by IRE1β optimizes mucin production in goblet cells | Q36637632 | ||
| Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains | Q36712468 | ||
| Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. | Q36763166 | ||
| Endoplasmic reticulum structure and interconnections with other organelles | Q36932847 | ||
| Cholera toxin, E. coli heat-labile toxin, and non-toxic derivatives induce dendritic cell migration into the follicle-associated epithelium of Peyer's patches | Q37038072 | ||
| IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Q37091581 | ||
| RETRACTED: The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling | Q37154230 | ||
| Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation | Q37191414 | ||
| From endoplasmic-reticulum stress to the inflammatory response | Q37225354 | ||
| The endoplasmic reticulum stress response in immunity and autoimmunity | Q37231726 | ||
| Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
| Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system | Q37555597 | ||
| Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome | Q37596032 | ||
| Signalling pathways in the unfolded protein response: development from yeast to mammals | Q37622607 | ||
| Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals | Q37639817 | ||
| Shiga toxins--from cell biology to biomedical applications | Q37659792 | ||
| Protein disulfide isomerase A6 controls the decay of IRE1α signaling via disulfide-dependent association | Q37687467 | ||
| Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells | Q37811174 | ||
| PAMPer and tRIGer: ligand-induced activation of RIG-I. | Q37865780 | ||
| How viruses and toxins disassemble to enter host cells | Q37891079 | ||
| The ER in 3D: a multifunctional dynamic membrane network | Q37928796 | ||
| The interplay between endoplasmic reticulum stress and inflammation. | Q37976265 | ||
| The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress. | Q37977999 | ||
| Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins | Q38037553 | ||
| Mapping the crossroads of immune activation and cellular stress response pathways | Q38098884 | ||
| Quality control: ER-associated degradation: protein quality control and beyond | Q38196654 | ||
| Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview. | Q38241810 | ||
| Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes? | Q38298375 | ||
| The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells. | Q38309617 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response | Q38614162 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 401-409 | |
| P577 | publication date | 2015-06-17 | |
| P1433 | published in | Trends in Immunology | Q15265730 |
| P1476 | title | Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway | |
| P478 | volume | 36 |
| Q47614555 | Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses. |
| Q26800781 | Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases |
| Q40051888 | Endoplasmic reticulum stress and unfolded protein response in infection by intracellular parasites. |
| Q38989169 | Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA. |
| Q38763648 | Epithelial ER Stress in Crohn's Disease and Ulcerative Colitis |
| Q64100174 | Expression of inositol-requiring enzyme 1β is downregulated in azoxymethane/dextran sulfate sodium-induced mouse colonic tumors |
| Q38727217 | Herpes Simplex Virus 1 UL41 Protein Suppresses the IRE1/XBP1 Signal Pathway of the Unfolded Protein Response via Its RNase Activity |
| Q55283549 | IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases. |
| Q39986343 | IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma |
| Q47242810 | Lower temperatures reduce type I interferon activity and promote alphaviral arthritis |
| Q92538749 | Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain |
| Q40077398 | NOD1 and NOD2: Beyond Peptidoglycan Sensing. |
| Q52674409 | PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD-RIG-I-NF-κB axis. |
| Q48768902 | Peroxisome proliferator-activated receptor alpha mediates C/EBP homologous protein to protect mice from acute liver failure |
| Q37343623 | Putative RNA-Directed Adaptive Mutations in Cancer Evolution |
| Q92451979 | Reactive oxygen species-mediated endoplasmic reticulum stress response induces apoptosis of Mycobacterium avium-infected macrophages by activating regulated IRE1-dependent decay pathway |
| Q39139037 | The role of the unfolded protein response in dengue virus pathogenesis. |
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