Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

scientific article

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production is …
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scholarly articleQ13442814

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P356DOI10.1038/NI.1824
P698PubMed publication ID19915568
P5875ResearchGate publication ID38091486

P50authorShizuo AkiraQ2279629
Gunther HartmannQ14467203
Stefan EndresQ16007075
Veit HornungQ16295222
Winfried BarchetQ30502596
Manuele RebsamenQ42121092
Jürgen RulandQ57773701
Martin SchleeQ84979057
P2093author name stringHiroki Kato
Christian Peschel
Satoshi Inoue
Simon Rothenfusser
Hendrik Poeck
Susanne Roth
Michael Bscheider
Olaf Gross
Katrin Finger
Nicole Hannesschläger
P2860cites workA Toll-like receptor recognizes bacterial DNAQ24290668
Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa BQ24290946
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8Q24310398
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virusQ24310706
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon inductionQ24318426
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASCQ24319706
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNAQ24319765
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasomeQ24319799
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusQ24336255
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogensQ24338114
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoterQ24558779
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silicaQ24649598
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1Q24650268
5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-IQ24653786
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA virusesQ27860455
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responsesQ27860685
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3Q27860854
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphatesQ27861007
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3Q27861127
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activityQ28118562
5'-Triphosphate RNA is the ligand for RIG-IQ28131726
Differential activation of the inflammasome by caspase-1 adaptors ASC and IpafQ28266417
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunityQ28504584
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNAQ28585347
Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNAQ28608975
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirusQ29615029
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expressionQ29615589
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentrationQ29615596
Requirement for caspase-8 in NF-kappaB activation by antigen receptor.Q34399988
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activationQ34920323
Signalling through C-type lectin receptors: shaping immune responsesQ34986405
Type I interferon signaling is required for activation of the inflammasome during Francisella infectionQ36229342
The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytesQ36634002
Innate recognition of virusesQ36950601
Inflammasome recognition of influenza virus is essential for adaptive immune responsesQ37061831
The caspase-1 inflammasome: a pilot of innate immune responsesQ37263621
Differential use of CARD9 by dectin-1 in macrophages and dendritic cellsQ37283130
Toll-like receptor and RIG-I-like receptor signalingQ37348422
CARD9 versus CARMA1 in innate and adaptive immunityQ37440232
RIG-I-like receptors: sensing and responding to RNA virus infectionQ37524808
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.Q39861713
The IFN regulatory factor 7-dependent type I IFN response is not essential for early resistance against murine cytomegalovirus infectionQ39873461
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanomaQ39922356
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulationQ41888241
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defenceQ46064734
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasomeQ51751254
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17Q56880713
TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral PathwayQ57018246
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptorsQ57184686
All roads lead to CARD9Q57265323
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
inflammasome complexQ412405
P304page(s)63-69
P577publication date2009-11-15
P1433published inNature ImmunologyQ1071725
P1476titleRecognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
P478volume11

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