Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

scientific article (publication date: 27 May 2011)

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.IMMUNI.2011.05.006
P3181OpenCitations bibliographic resource ID248654
P698PubMed publication ID21616434
P5875ResearchGate publication ID51168855

P2093author name stringAkira S
Kawai T
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)637-50
P577publication date2011-05-27
P1433published inImmunityQ6005457
P1476titleToll-like receptors and their crosstalk with other innate receptors in infection and immunity
P478volume34

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cites work (P2860)
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Q41025089Effector responses of bovine blood neutrophils against Escherichia coli: Role of NOD1/NF-κB signalling pathway
Q52585912Effects of Lactobacillus reuteri LR1 on the growth performance, intestinal morphology and intestinal barrier function in weaned pigs.
Q57016056Effects of different principles of Traditional Chinese Medicine treatment on TLR7/NF-κB signaling pathway in influenza virus infected mice
Q34452601Effects of over-expression of TLR2 in transgenic goats on pathogen clearance and role of up-regulation of lysozyme secretion and infiltration of inflammatory cells
Q54202535Efficient Uptake of Recombinant Lipidated Survivin by Antigen-Presenting Cells Initiates Antigen Cross-Presentation and Antitumor Immunity.
Q50045989Emerging Roles for Epigenetic Programming in the Control of Inflammatory Signaling Integration in Heath and Disease.
Q35802197Emerging roles for multipotent, bone marrow-derived stromal cells in host defense
Q38325712Emerging roles of innate immune signaling and toll-like receptors in fibrosis and systemic sclerosis
Q36527353Encephalitozoon intestinalis Inhibits Dendritic Cell Differentiation through an IL-6-Dependent Mechanism
Q38301981Endogenous intracellular cathelicidin enhances TLR9 activation in dendritic cells and macrophages.
Q36566594Endometriosis, a disease of the macrophage
Q40543475Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia
Q27027733Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases
Q39267904Endoplasmic reticulum stress regulates the innate immunity critical transcription factor IRF3.
Q38946746Endosomal sensing of fungi: current understanding and emerging concepts.
Q42152351Endosomes are specialized platforms for bacterial sensing and NOD2 signalling
Q36711988Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases
Q36510868Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis.
Q36921721Enhanced Dendritic Cell-Mediated Antigen-Specific CD4+ T Cell Responses: IFN-Gamma Aids TLR Stimulation
Q37584293Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M.
Q36246023Enhanced susceptibility to lipopolysaccharide-induced arthritis and endotoxin shock in interleukin-32 alpha transgenic mice through induction of tumor necrosis factor alpha
Q54249868Enteric Virome Sensing-Its Role in Intestinal Homeostasis and Immunity.
Q92301856Enterohemorrhagic Escherichia coli Tir inhibits TAK1 activation and mediates immune evasion
Q48163302Entomopathogenicity and Biological Attributes of Himalayan Treasured Fungus Ophiocordyceps sinensis (Yarsagumba).
Q40518541Environment impacts innate immune ontogeny
Q36200357Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling
Q38886548Epigenetic Mechanisms Governing Innate Inflammatory Responses.
Q90018727Epigenetic regulation of Toll-like receptors and its roles in type 1 diabetes
Q40720458Epithelial Cell-Derived Secreted and Transmembrane 1a Signals to Activated Neutrophils during Pneumococcal Pneumonia.
Q40337014Epithelial Myeloid-Differentiation Factor 88 Is Dispensable during Klebsiella Pneumonia
Q89901094Epithelial Toll-like receptors and their role in gut homeostasis and disease
Q99237928Establishment of a Stable β-Casein Protein-Secreted Laoshan Dairy Goat Mammary Epithelial Cell Line
Q91711356Evaluating the Causal Role of Gut Microbiota in Type 1 Diabetes and Its Possible Pathogenic Mechanisms
Q89286883Evaluation of tool-like receptor-2 and 4 and interleukin-6 gene expressions in Turkish rheumatoid arthritis patients
Q39767650Evaluation of various adjuvant nanoparticulate formulations for meningococcal capsular polysaccharide-based vaccine.
Q38061423Evasion of influenza A viruses from innate and adaptive immune responses.
Q41539920Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection
Q41174284Exploiting Antitumor Immunotherapeutic Novel Strategies by Deciphering the Cross Talk between Invariant NKT Cells and Dendritic Cells
Q47933664Expression of Toll-Like Receptors in Chronic Histiocytic Intervillositis of the Placenta
Q47855388Expression of human cathelicidin peptide LL-37 in inflammatory bowel disease.
Q35195258Expression of inhibitory regulators of innate immunity in patients with active tuberculosis
Q35161931Expression of olfactory signaling genes in the eye
Q50871361Extracellular Hsp70 inhibits pro-inflammatory cytokine production by IL-10 driven down-regulation of C/EBPβ and C/EBPδ.
Q39196702Extracellular Vesicles Deliver Host and Virus RNA and Regulate Innate Immune Response
Q39388118Extracellular Vesicles Including Exosomes Regulate Innate Immune Responses to Hepatitis B Virus Infection.
Q31083760Extracellular polysaccharides produced by Ganoderma formosanum stimulate macrophage activation via multiple pattern-recognition receptors
Q36764697FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Q39301452FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights
Q34974190FSL-1, a Toll-like Receptor 2/6 Agonist, Induces Expression of Interleukin-1α in the Presence of 27-hydroxycholesterol
Q51847569Feasibility of Applying Helper-Dependent Adenoviral Vectors for Cancer Immunotherapy.
Q94562552Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity
Q28546726Fever Is Mediated by Conversion of Endocannabinoid 2-Arachidonoylglycerol to Prostaglandin E2
Q47780784Ficolin-1 is up-regulated in leukocytes and glomeruli from microscopic polyangiitis patients
Q91620661Flaming and fanning: The Spectrum of inflammatory influences in myelodysplastic syndromes
Q39467732For Whom the Bell Tolls (and Nods): Spit-acular Saliva.
Q34290672Formal modelling of toll like receptor 4 and JAK/STAT signalling pathways: insight into the roles of SOCS-1, interferon-β and proinflammatory cytokines in sepsis
Q35184964Formation of NET, phagocytic activity, surface architecture, apoptosis and expression of toll like receptors 2 and 4 (TLR2 and TLR4) in neutrophils of mastitic cows.
Q43047786Formation of membrane-defined compartments by tick-borne encephalitis virus contributes to the early delay in interferon signaling.
Q34359869From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation
Q88576669From allergen to oral vaccine carrier: A new face of ragweed pollen
Q87966506Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation
Q57008273Functional Polymorphisms in Are Related to Hepatocellular Carcinoma Risk in Chinese Population
Q39123215Functional characterization of porcine LSm14A in IFN-β induction.
Q37971025Fungal surface and innate immune recognition of filamentous fungi
Q90281584GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses
Q54340493GHIP in Streptococcus pneumoniae is involved in antibacterial resistance and elicits a strong innate immune response through TLR2 and JNK/p38MAPK.
Q37676303Gene Deletion in Barley Mediated by LTR-retrotransposon BARE.
Q59807319Gene Regulatory Network Modeling of Macrophage Differentiation Corroborates the Continuum Hypothesis of Polarization States
Q34708456Gene expression analysis of peripheral blood cells reveals Toll-like receptor pathway deregulation in colorectal cancer
Q30100964Gene expression patterns induced at different stages of rhinovirus infection in human alveolar epithelial cells
Q99240231Gene expression profiles of the small intestine of village chickens from an Ascaridia galli infested environment
Q28081911Gene therapy for hemophilia
Q40541173General, but not myeloid or type II lung epithelial cell, myeloid differentiation factor 88 deficiency abrogates house dust mite induced allergic lung inflammation.
Q51253926Generation of Immunostimulating 130 nm Protamine-RNA nanoparticles.
Q38726846Genetic Variability as a Regulator of TLR4 and NOD Signaling in Response to Bacterial Driven DNA Damage Response (DDR) and Inflammation: Focus on the Gastrointestinal (GI) Tract
Q38537340Genetic susceptibility to invasive Salmonella disease
Q35973321Genipin attenuates sepsis by inhibiting Toll-like receptor signaling
Q35234300Genome and infection characteristics of human parechovirus type 1: the interplay between viral infection and type I interferon antiviral system
Q37042841Genome-wide transcriptional analysis of differentially expressed genes in flagellin-pretreated mouse corneal epithelial cells in response to Pseudomonas aeruginosa: involvement of S100A8/A9.
Q37335980Global transcriptome analysis of Staphylococcus aureus biofilms in response to innate immune cells
Q91782691Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
Q35677343Gut Microbiota and Immunity: Possible Role in Sudden Infant Death Syndrome
Q51144461Gut Microbiota and Type 1 Diabetes.
Q26795634Gut microbiota and allogeneic transplantation
Q100946013Gut microbiota in pancreatic diseases: possible new therapeutic strategies
Q38371533Gut-liver axis: role of inflammasomes
Q35745385HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1
Q41492683HIV-1 single-stranded RNA induces CXCL13 secretion in human monocytes via TLR7 activation and plasmacytoid dendritic cell-derived type I IFN.
Q38234190HIV-1 translation and its regulation by cellular factors PKR and PACT.
Q40513220HIV-1-derived single-stranded RNA acts as activator of human neutrophils
Q40561877HIV-1-neutrophil interactions trigger neutrophil activation and Toll-like receptor expression
Q60949697HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways
Q37746179Harnessing RNA sequencing for global, unbiased evaluation of two new adjuvants for dendritic-cell immunotherapy.
Q35021728Helicobacter pylori cag pathogenicity island (cagPAI) involved in bacterial internalization and IL-8 induced responses via NOD1- and MyD88-dependent mechanisms in human biliary epithelial cells
Q34257461Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis
Q36132799Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses
Q91942492Hepatitis B Core Antigen Impairs the Polarization While Promoting the Production of Inflammatory Cytokines of M2 Macrophages via the TLR2 Pathway
Q104461548Hepatitis B virus exploits C-type lectin receptors to hijack cDC1s, cDC2s and pDCs
Q35270150Hepatitis C virus and antiviral innate immunity: who wins at tug-of-war?
Q37546397Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6
Q28115766Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1
Q38032237Herpesviral infection and Toll-like receptor 2
Q64125300Hes1 attenuates type I IFN responses via VEGF-C and WDFY1
Q37304605High-Level Expression of Toll-Like Receptors on Dendritic Cells in Adult Patients with Burns on ≥90% of Total Body Surface Area (TBSA)
Q36446942Histo-cytometry: a method for highly multiplex quantitative tissue imaging analysis applied to dendritic cell subset microanatomy in lymph nodes
Q41137548Histopathological findings and detection of Toll-like receptor 2 in cutaneous lesions of canine leishmaniosis
Q46540922Histopathology and analyses of inflammation intensity in the gills of mussels exposed to silver nanoparticles: role of nanoparticle size, exposure time, and uptake pathways
Q26744647Host Intracellular Signaling Events and Pro-inflammatory Cytokine Production in African Trypanosomiasis
Q26745544How Mouse Macrophages Sense What Is Going On.
Q42051486Human Coronaviruses: A Review of Virus-Host Interactions.
Q60938439Human Plasmacytoid and Monocyte-Derived Dendritic Cells Display Distinct Metabolic Profile Upon RIG-I Activation
Q37309932Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes
Q95819383Human Type I Interferon Antiviral Effects in Respiratory and Reemerging Viral Infections
Q41234493Human blood CD1c dendritic cells stimulate IL-12-independent IFN-γ responses and have a strikingly low inflammatory profile
Q87131050Human blood dendritic cell subsets exhibit discriminative pattern recognition receptor profiles
Q33826814Human decidual macrophages and NK cells differentially express Toll-like receptors and display distinct cytokine profiles upon TLR stimulation
Q89749294Human genetics of meningococcal infections
Q42152387Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA.
Q39013184Hydroxychloroquine restores trophoblast fusion affected by antiphospholipid antibodies
Q37084383Hydroxysafflor Yellow A Inhibits LPS-Induced NLRP3 Inflammasome Activation via Binding to Xanthine Oxidase in Mouse RAW264.7 Macrophages
Q34255700IBD-what role do Proteobacteria play?
Q40230945IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3.
Q47274901IFN-β: A Contentious Player in Host-Pathogen Interaction in Tuberculosis.
Q48266994IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology
Q98303246IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes
Q27008536IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
Q35023529IL-1α signaling is critical for leukocyte recruitment after pulmonary Aspergillus fumigatus challenge
Q62761935INH14, a Small-Molecule Urea Derivative, Inhibits the IKKα/β-Dependent TLR Inflammatory Response
Q45988243IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.
Q33611375IRAK4 Deficiency in a Patient with Recurrent Pneumococcal Infections: Case Report and Review of the Literature
Q37022835IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance
Q40488209IRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease.
Q94561551IRF-7 Mediates Type I IFN Responses in Endotoxin-Challenged Mice
Q37513344IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation
Q54117915Idelalisib impairs TREM-1 mediated neutrophil inflammatory responses.
Q34447799Identification and function of myeloid differentiation factor 88 (MyD88) in Litopenaeus vannamei
Q38060973Identification and utility of innate immune system evasion mechanisms of ASFV.
Q44759466Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages
Q40329067Identification of a Novel Splice Variant Isoform of TREM-1 in Human Neutrophil Granules.
Q26798033Identifying Novel Targets for Treatment of Liver Fibrosis: What Can We Learn from Injured Tissues which Heal Without a Scar?
Q36665677Identifying metabolite markers for preterm birth in cervicovaginal fluid by magnetic resonance spectroscopy
Q28601166IgG1 Fc N-glycan galactosylation as a biomarker for immune activation
Q92863312Immune Response Mechanisms against AAV Vectors in Animal Models
Q30250232Immune evasion of porcine enteric coronaviruses and viral modulation of antiviral innate signaling
Q42542433Immune receptor signaling: from ubiquitination to NF-κB activation
Q40044806Immune regulation of miR-30 on the Mycobacterium tuberculosis-induced TLR/MyD88 signaling pathway in THP-1 cells
Q38517886Immune response triggered by Brucella abortus following infection or vaccination
Q35023274Immune responses to human factor IX in haemophilia B mice of different genetic backgrounds are distinct and modified by TLR4.
Q34657561Immune therapy for human papillomaviruses-related cancers
Q89530611Immune-related miRNA-mRNA regulation network in the livers of DHAV-3-infected ducklings
Q47561286Immunity against hepatitis E virus infection: Implications for therapy and vaccine development
Q35424070Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice
Q24632664Immunodeficiency and autoimmunity: lessons from systemic lupus erythematosus
Q47550799Immunological Tolerance, Pregnancy, and Preeclampsia: The Roles of Semen Microbes and the Father
Q38242227Immunological and technical considerations in application of alginate-based microencapsulation systems
Q39198568Immunological effects of a novel RNA-based adjuvant in liver cancer patients
Q37990026Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes.
Q42569454Immunology. Orchestrating inflammasomes
Q37123761Immunosuppressive property within the Streptococcus pneumoniae cell wall that inhibits generation of T follicular helper, germinal center, and plasma cell response to a coimmunized heterologous protein
Q39214573Impact of host membrane pore formation by the Yersinia pseudotuberculosis type III secretion system on the macrophage innate immune response
Q90185646Impact of infection on transplantation tolerance
Q91173676Impaired antigen-specific lymphocyte priming in mice after Toll-like receptor 4 activation via induction of monocytic myeloid-derived suppressor cells
Q34950159Impaired blood dendritic cell numbers and functions after aneurysmal subarachnoid hemorrhage
Q47995810Implications of SNPs on toll-like receptor genes in malaria: what do we know?
Q35759651Inborn errors of anti-viral interferon immunity in humans
Q40383158Incidence of cervical human papillomavirus infection in systemic lupus erythematosus women.
Q48102522Increased Abundance of Plasmacytoid Dendritic Cells and Interferon-Alpha Induces Plasma Cell Differentiation in Patients of IgA Nephropathy
Q90626233Increased SAMHD1 transcript expression correlates with interferon-related genes in HIV-1-infected patients
Q33644230Increased expression of CD25, CD83, and CD86, and secretion of IL-12, IL-23, and IL-10 by human dendritic cells incubated in the presence of Toll-like receptor 2 ligands and Giardia duodenalis
Q61053414Increased influenza-specific antibody avidity in HIV-infected women compared with HIV-infected men on antiretroviral therapy.
Q40268002Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex.
Q40318493Inducible microRNA-214 contributes to the suppression of NF-κB-mediated inflammatory response via targeting myd88 gene in fish
Q52649839Induction and Subversion of Human Protective Immunity: Contrasting Influenza and Respiratory Syncytial Virus.
Q37949459Induction and evasion of type I interferon responses by influenza viruses
Q47626357Induction of antigen-specific TH 9 immunity accompanied by mast cell activation blocks tumor cell engraftment
Q37626826Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells
Q26800014Induction of innate immunity and its perturbation by influenza viruses
Q28545027Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii
Q64954407Induction of pro-inflammatory cytokines by 29-kDa FN-f via cGAS/STING pathway.
Q34701875Inefficient TLR4/MD-2 heterotetramerization by monophosphoryl lipid A
Q36895344Infection-induced IL-10 and JAK-STAT: A review of the molecular circuitry controlling immune hyperactivity in response to pathogenic microbes
Q41684112Inflammasomes and Cancer: The Dynamic Role of the Inflammasome in Tumor Development
Q90683704Inflammasomes in the pathophysiology of autoinflammatory syndromes
Q61802943Inflammasomes, Autophagy, and Cell Death: The Trinity of Innate Host Defense against Intracellular Bacteria
Q50127096Inflammation in Vein Graft Disease.
Q36803719Inflammation, fracture and bone repair
Q38200891Inflammatory response of macrophages in infection
Q42945799Influence of tumors on protective anti-tumor immunity and the effects of irradiation.
Q38018843Information processing during phagocytosis
Q35832150Inherited variation in pattern recognition receptors and cancer: dangerous liaisons?
Q40119941Inhibition of NF-κB activity by the porcine epidemic diarrhea virus nonstructural protein 1 for innate immune evasion.
Q37713902Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response.
Q35096709Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells.
Q33975195Inhibitory effect of tanshinone IIA on rat hepatic stellate cells
Q37939843Innate Immune Responses to AAV Vectors
Q26773329Innate Immunity and Immune Evasion by Enterovirus 71
Q52579155Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy.
Q38687463Innate Immunity: Orchestrating Inflammation and Resolution of Otitis Media.
Q59351679Innate Sensing of DNA Virus Genomes
Q37953311Innate and adaptive immune responses against Staphylococcus aureus skin infections
Q38560972Innate detection of hepatitis B and C virus and viral inhibition of the response
Q37262877Innate immune cell response upon Candida albicans infection
Q36511529Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly
Q37380130Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways
Q37678709Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand
Q33631244Innate immune recognition of flagellin limits systemic persistence of Brucella
Q36865871Innate immune reconstitution with suppression of HIV-1.
Q62485204Innate immune response in patients with acute Zika virus infection
Q27023055Innate immune responses in hepatitis C virus infection
Q38118170Innate immune responses in the CNS: role of toll-like receptors, mechanisms, and therapeutic opportunities in multiple sclerosis
Q27027584Innate immune responses to DNA viruses
Q30365302Innate immune sensing and response to influenza.
Q27002611Innate immune signaling in defense against intestinal microbes
Q27010187Innate immunity against Leishmania infections
Q27000453Innate immunity and its regulation by mast cells
Q38603671Innate immunity in CKD-associated vascular diseases.
Q39232871Innate immunity in Sjögren's syndrome.
Q92494838Innate immunity in allergy
Q37451325Innate immunity interactome dynamics
Q36482747Innate immunity to H5N1 influenza viruses in humans
Q37718852Innate immunity to adenovirus
Q48292170Innate immunity's path to the Nobel Prize 2011 and beyond
Q36283976Innate immunostimulatory properties of allergens and their relevance to food allergy
Q33900037Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection
Q39441971Innate sensing of foamy viruses by human hematopoietic cells
Q92501740Innate signaling within the central nervous system recruits protective neutrophils
Q34990211Inorganic polyphosphate suppresses lipopolysaccharide-induced inducible nitric oxide synthase (iNOS) expression in macrophages
Q28087310Insights into the antiviral immunity against grass carp (Ctenopharyngodon idella) reovirus (GCRV) in grass carp
Q37605215Insights on adaptive and innate immunity in canine leishmaniosis
Q30846313Integrative modelling of TIR domain-containing adaptor molecule inducing interferon-β (TRIF) provides insights into its autoinhibited state
Q34241809Integrin-mediated first signal for inflammasome activation in intestinal epithelial cells
Q33689702Interaction between Plasmodium Glycosylphosphatidylinositol and the Host Protein Moesin Has No Implication in Malaria Pathology
Q38944175Interaction of Bordetella pertussis filamentous hemagglutinin with human TLR2: identification of the TLR2-binding domain.
Q35014476Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis
Q61813504Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System
Q46237015Interferon Potentiates Toll-Like Receptor-Induced Prostaglandin D2 Production through Positive Feedback Regulation between Signal Transducer and Activators of Transcription 1 and Reactive Oxygen Species
Q37093160Interferon regulatory factor 3 is a key regulation factor for inducing the expression of SAMHD1 in antiviral innate immunity
Q37320379Interferon regulatory factor-1 in flagellin-induced reprogramming: potential protective role of CXCL10 in cornea innate defense against Pseudomonas aeruginosa infection
Q91345396Interferon target-gene expression and epigenomic signatures in health and disease
Q34114819Interferon-inducible effector mechanisms in cell-autonomous immunity
Q34405609Interferon-stimulated genes: a complex web of host defenses
Q40182958Interferon-β response is impaired by hepatitis B virus infection in Tupaia belangeri
Q43214205Interleukin-18 increases TLR4 and mannose receptor expression and modulates cytokine production in human monocytes
Q64105292Intermittent Fasting Exacerbates the Acute Immune and Behavioral Sickness Response to the Viral Mimic Poly(I:C) in Mice
Q28081406International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease
Q38573911Interplay between HIV-1 and Toll-like receptors in human myeloid cells: friend or foe in HIV-1 pathogenesis?
Q34212787Interplay between innate immunity and negative-strand RNA viruses: towards a rational model
Q91578240Interplays between Enterovirus A71 and the innate immune system
Q90390299Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression
Q38054086Intestinal antimicrobial peptides during homeostasis, infection, and disease
Q35830335Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells
Q91907950Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling
Q34850331Intracellular delivery of lipopolysaccharide induces effective Th1-immune responses independent of IL-12.
Q37925070Intracellular sensing of microbes and danger signals by the inflammasomes
Q64263180Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice
Q39043844Intratumoral Delivery of Immunotherapy-Act Locally, Think Globally
Q28709929Intrinsic antiviral immunity
Q53624062Invasive Streptococcus mutans induces inflammatory cytokine production in human aortic endothelial cells via regulation of intracellular toll-like receptor 2 and nucleotide-binding oligomerization domain 2.
Q38050450Jack of all trades: thymosin α1 and its pleiotropy
Q39287361Joint replacement surgery and the innate immune system
Q64943265Key mechanisms involved in ionizing radiation-induced systemic effects. A current review.
Q26822456Killing two birds with one stone: trans-kingdom suppression of PAMP/MAMP-induced immunity by T3E from enteropathogenic bacteria
Q36200269Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity
Q46680179Kinases conquer the inflammasomes
Q36976064Kinetics of the West Nile virus induced transcripts of selected cytokines and Toll-like receptors in equine peripheral blood mononuclear cells
Q36206938Kluyveromyces marxianus and Saccharomyces boulardii Induce Distinct Levels of Dendritic Cell Cytokine Secretion and Significantly Different T Cell Responses In Vitro
Q61808827L. Methanol Extract Has Anti-Inflammatory Activity Targeting Src/Syk via NF-κB Inhibition
Q34516808LGP2 expression is enhanced by interferon regulatory factor 3 in olive flounder, Paralichthys olivaceus
Q57055081LL-37 inhibits LPS-induced inflammation and stimulates the osteogenic differentiation of BMSCs via P2X7 receptor and MAPK signaling pathway
Q47317822LPS upregulates palmitoylated enzymes of the phosphatidylinositol cycle. An insight from proteomic studies.
Q59136167LPS-stimulated NF-κB p65 dynamic response marks the initiation of TNF expression and transition to IL-10 expression in RAW 264.7 macrophages
Q39206438LRRK2 and the Immune System
Q38939318LSM14A inhibits porcine reproductive and respiratory syndrome virus (PRRSV) replication by activating IFN-β signaling pathway in Marc-145.
Q28594149LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection
Q40145629Lavandula angustifolia Mill. Essential Oil Exerts Antibacterial and Anti-Inflammatory Effect in Macrophage Mediated Immune Response to Staphylococcus aureus
Q91904124Leishmania donovani Lipophosphoglycan Increases Macrophage-Dependent Chemotaxis of CXCR6-Expressing Cells via CXCL16 Induction
Q38873769Leishmania donovani influenced cytokines and Toll-like receptors expression among Sudanese visceral leishmaniasis patients
Q90638116Leucine Rich Repeat Kinase 2 and Innate Immunity
Q30412353Leucine-Rich Repeat (LRR) Domains Containing Intervening Motifs in Plants
Q90317183Leucine-rich repeats and calponin homology containing 4 (Lrch4) regulates the innate immune response
Q55208863Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells.
Q28389004Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids
Q55188236Lipids From Trypanosoma cruzi Amastigotes of RA and K98 Strains Generate a Pro-inflammatory Response via TLR2/6.
Q34071368Lipopolysaccharide (LPS) inhibits steroid production in theca cells of bovine follicles in vitro: distinct effect of LPS on theca cell function in pre- and post-selection follicles
Q88670253Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKϵ-IRF3 axis activation
Q37363183Lipopolysaccharide Attenuates Induction of Proallergic Cytokines, Thymic Stromal Lymphopoietin, and Interleukin 33 in Respiratory Epithelial Cells Stimulated with PolyI:C and Human Parechovirus
Q47956445Lipopolysaccharide regulates biosynthesis of cystathionine γ-lyase and hydrogen sulfide through Toll-like receptor-4/p38 and Toll-like receptor-4/NF-κB pathways in macrophages
Q29994846Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
Q34658112Liposomal lipopolysaccharide initiates TRIF-dependent signaling pathway independent of CD14.
Q38920945Lipoteichoic acids as a major virulence factor causing inflammatory responses via Toll-like receptor 2.
Q36977730Listeria monocytogenes: a promising vehicle for neonatal vaccination
Q37027482Lithium chloride promotes host resistance against Pseudomonas aeruginosa keratitis
Q57753328Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5
Q92659707Long non-coding RNA expressed in macrophage co-varies with the inflammatory phenotype during macrophage development and polarization
Q38769321Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity
Q34342336Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis
Q36421994Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease
Q38810913Lymph node - an organ for T-cell activation and pathogen defense.
Q27321636Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node.
Q35061594Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-κB translocation and MAPK/ERK phosphorylation
Q48327546M1 Means Kill; M2 Means Heal.
Q35600855M1 and M2 macrophages: the chicken and the egg of immunity
Q47275125MAPK/AP-1-Targeted Anti-Inflammatory Activities of Xanthium strumarium
Q42259864MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion
Q92446931MGL1 Receptor Plays a Key Role in the Control of T. cruzi Infection by Increasing Macrophage Activation through Modulation of ERK1/2, c-Jun, NF-κB and NLRP3 Pathways
Q36617801MRP8/14 enhances corneal susceptibility to Pseudomonas aeruginosa Infection by amplifying inflammatory responses.
Q34053805Macrophage- and neutrophil-derived TNF-α instructs skin langerhans cells to prime antiviral immune responses
Q27027100Macrophage: SHIP of Immunity
Q39331723Macrophages as Effectors of Acute and Chronic Allograft Injury
Q37147624Macrophages in tuberculosis: friend or foe.
Q41071548Macrophages recognize the Helicobacter pylori type IV secretion system in the absence of toll-like receptor signalling
Q37632332Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability
Q38585903Making sense of viral RNA sensing.
Q38314624Mannose receptor and macrophage galactose-type lectin are involved in Bordetella pertussis mast cell interaction
Q39044328Mannoside recognition and degradation by bacteria.
Q34575737Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection
Q38098884Mapping the crossroads of immune activation and cellular stress response pathways
Q41924275Marginal zone B cells are critical to factor VIII inhibitor formation in mice with hemophilia A.
Q36013705Mast Cells are Important Modifiers of Autoimmune Disease: With so Much Evidence, Why is There Still Controversy?
Q38647493Mechanism of Action of Probiotic Bacteria on Intestinal and Systemic Immunities and Antigen-Presenting Cells
Q88780114Mechanism of Activation of Enteric Nociceptive Neurons via Interaction of TLR4 and TRPV1 Receptors
Q37134468Mechanisms Underlying the Immune Response Generated by an Oral Vibrio cholerae Vaccine
Q28087160Mechanisms of Borrelia burgdorferi internalization and intracellular innate immune signaling
Q40567470Meet the terminator: The phosphatase PP2A puts brakes on IRF-3 activation
Q39411267Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88.
Q35936721Messenger functions of the bacterial cell wall-derived muropeptides
Q36994631Metabolic host responses to infection by intracellular bacterial pathogens
Q37257891Methylcrotonoyl-CoA carboxylase 1 potentiates RLR-induced NF-κB signaling by targeting MAVS complex
Q37351181MiR-146 and miR-125 in the regulation of innate immunity and inflammation
Q33913945MiR-146a negatively regulates dectin-1-induced inflammatory responses
Q38020839Mice, men and the relatives: cross-species studies underpin innate immunity
Q90221850MicroRNA-1294 inhibited oral squamous cell carcinoma growth by targeting c-Myc
Q58103548MicroRNA-221-5p Inhibits Porcine Epidemic Diarrhea Virus Replication by Targeting Genomic Viral RNA and Activating the NF-κB Pathway
Q40863421MicroRNA-381 Negatively Regulates TLR4 Signaling in A549 Cells in Response to LPS Stimulation
Q36685269MicroRNA-92a negatively regulates Toll-like receptor (TLR)-triggered inflammatory response in macrophages by targeting MKK4 kinase
Q35883959MicroRNA-induced negative regulation of TLR-5 in grass carp, Ctenopharyngodon idella
Q37729606MicroRNAs in the regulation of TLR and RIG-I pathways
Q34275780Microbe-specific C3b deposition in the horseshoe crab complement system in a C2/factor B-dependent or -independent manner
Q92617569Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization
Q38130307Microbial activation of gut dendritic cells and the control of mucosal immunity
Q90019254Microbial biomarkers for immune checkpoint blockade therapy against cancer
Q39099480Microbial recognition and danger signals in sepsis and trauma
Q38055345Microbial recognition and evasion of host immunity.
Q48208431Microglial activation and expression of immune-related genes in a rat ex vivo nervous system model after infection with Listeria monocytogenes
Q37949246Microglial cell origin and phenotypes in health and disease
Q89782356Microtubule-Mediated NLRP3 Inflammasome Activation Is Independent of Microtubule-Associated Innate Immune Factor GEF-H1 in Murine Macrophages
Q37907827Mitochondria in innate immunity
Q89967562Mitochondrial Interactome: A Focus on Antiviral Signaling Pathways
Q38907926Mitochondrial function, ornamentation, and immunocompetence
Q93062900Mitophagy and Innate Immunity in Infection
Q38073752Modern subunit vaccines: development, components, and research opportunities
Q35151746Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway
Q28079739Modulation of the Inflammasome Signaling Pathway by Enteropathogenic and Enterohemorrhagic Escherichia coli
Q49997050Modulators of innate immunity as novel therapeutics for treatment of chronic hepatitis B.
Q28552636Molecular Determinants of GS-9620-Dependent TLR7 Activation
Q58784853Molecular Targets in Hepatocarcinogenesis and Implications for Therapy
Q55397871Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine.
Q38593252Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction.
Q91555628Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses
Q37950957Molecular battle between host and bacterium: recognition in innate immunity
Q36041225Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling
Q38953543Molecular pathways driving disease-specific alterations of intestinal epithelial cells
Q94921992More Than Just a Barrier: The Immune Functions of the Airway Epithelium in Asthma Pathogenesis
Q38991040More than complementing Tolls: complement-Toll-like receptor synergy and crosstalk in innate immunity and inflammation
Q36157637Morphine modulation of toll-like receptors in microglial cells potentiates neuropathogenesis in a HIV-1 model of coinfection with pneumococcal pneumoniae
Q36890675Mouse embryonic stem cells are deficient in type I interferon expression in response to viral infections and double-stranded RNA.
Q37610646Mouse embryonic stem cells have underdeveloped antiviral mechanisms that can be exploited for the development of mRNA-mediated gene expression strategy.
Q26830597Mucins and toll-like receptors: kith and kin in infection and cancer
Q43091398Mucocutaneous leishmaniasis and an undesired passenger
Q37737825Multifaceted roles of TRIM38 in innate immune and inflammatory responses
Q40202938Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice
Q34361820Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases
Q39346211Multiple functions of the E3 ubiquitin ligase CHIP in immunity
Q36499739Mumps virus-induced innate immune responses in mouse Sertoli and Leydig cells
Q39098027Mutational analysis identifies residues crucial for homodimerization of myeloid differentiation factor 88 (MyD88) and for its function in immune cells.
Q44846074MyD88 knockout mice develop initial enlarged periapical lesions with increased numbers of neutrophils
Q37546441MyD88 signaling is directly involved in the development of murine placental malaria
Q28512466MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response
Q39081826Mycobacterial phenolic glycolipids with a simplified lipid aglycone modulate cytokine levels through Toll-like receptor 2.
Q84574057Mycobacterium indicus pranii mediates macrophage activation through TLR2 and NOD2 in a MyD88 dependent manner
Q28483659Mycoepoxydiene inhibits lipopolysaccharide-induced inflammatory responses through the suppression of TRAF6 polyubiquitination [corrected]
Q35840578Mycoplasma hyorhinis-Contaminated Cell Lines Activate Primary Innate Immune Cells via a Protease-Sensitive Factor
Q92714157Myeloid and Plasmacytoid Dendritic Cells and Cancer - New Insights
Q39142554NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases
Q37995678NF-κB: where did it come from and why?
Q35980771NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection
Q28507530NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
Q38261239NLRP3 inflammasome activation: CD36 serves double duty
Q26865199NOD-Like Receptors: Master Regulators of Inflammation and Cancer
Q48186747NOD1 downregulates intestinal serotonin transporter and interacts with other pattern recognition receptors
Q89206258NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation
Q58583890Nanoparticle Vaccines Against Infectious Diseases
Q35772526Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness
Q38683067Natural Nuclear Factor Kappa Beta Inhibitors: Safe Therapeutic Options for Inflammatory Bowel Disease
Q37722341Necrosis-dependent and independent signaling of the RIP kinases in inflammation
Q59355501Negative regulation of MAVS-mediated antiviral signaling by the mitochondrial protein LRPPRC during HCV infection
Q26823812Neonatal host defense against Staphylococcal infections
Q26824171Neonatal sepsis due to coagulase-negative staphylococci
Q28552480Network Analysis of Human Genes Influencing Susceptibility to Mycobacterial Infections
Q30662482Network fingerprint: a knowledge-based characterization of biomedical networks
Q39299529Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis.
Q40254144Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.
Q29616689Neutrophil recruitment and function in health and inflammation
Q34244806Neutrophils express distinct RNA receptors in a non-canonical way.
Q58905565New Aspects in Immunopathology of Mycobacterium tuberculosis
Q52592867New antimicrobial peptide kills drug-resistant pathogens without detectable resistance.
Q40131760New findings of Toll-like receptors involved in Mycobacterium tuberculosis infection
Q33721868New insights into TRP channels: Interaction with pattern recognition receptors
Q40158428Newcastle disease virus-like particles induce DC maturation through TLR4/NF-κB pathway and facilitate DC migration by CCR7-CCL19/CCL21 axis
Q38138089Next-generation therapeutic solutions for age-related macular degeneration
Q53698735No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases.
Q36880291Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin
Q36932454Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.
Q90003022Norovirus encounters in the gut: multifaceted interactions and disease outcomes
Q37626086Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling
Q34999938Novel drugs targeting Toll-like receptors for antiviral therapy
Q38212211Novel role of toll-like receptors in Helicobacter pylori - induced gastric malignancy
Q33900347Novel roles of cytoplasmic ICP0: proteasome-independent functions of the RING finger are required to block interferon-stimulated gene production but not to promote viral replication
Q91864937Nucleic Acid Sensing at the Interface Between Innate and Adaptive Immunity
Q95425660Nucleic Acid Sensing at the Interface Between Innate and Adaptive Immunity
Q28534779Nucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responses
Q39011657Nucleic acid sensing and innate immunity: signaling pathways controlling viral pathogenesis and autoimmunity
Q38021271Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination
Q38673412Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology
Q39725033Nucleotide-binding oligomerization domain-1 and -2 play no role in controlling Brucella abortus infection in mice
Q37064228Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection
Q57753388OAS1 and OAS3 negatively regulate the expression of chemokines and interferon-responsive genes in human macrophages
Q26998188Obstetrical antiphospholipid syndrome: from the pathogenesis to the clinical and therapeutic implications
Q37418679Olfactory bulb and hypothalamic acute-phase responses to influenza virus: effects of immunization
Q36586115Oligodeoxynucleotides expressing polyguanosine motifs promote antitumor activity through the upregulation of IL-2.
Q35765830On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death
Q38208315Oncolytic virus-mediated reversal of impaired tumor antigen presentation
Q40179542Oncostatin M induces RIG-I and MDA5 expression and enhances the double-stranded RNA response in fibroblasts
Q34427383Ontogeny of Toll-like receptor mediated cytokine responses of South African infants throughout the first year of life.
Q26774692Optimizing Outcomes in Immunocompromised Hosts: Understanding the Role of Immunotherapy in Invasive Fungal Diseases
Q28392127Oxidized phosphatidylserine: production and bioactivities
Q38816586PACT- and RIG-I-Dependent Activation of Type I Interferon Production by a Defective Interfering RNA Derived from Measles Virus Vaccine
Q39182894PI5P and PI(3,5)P2: Minor, but Essential Phosphoinositides.
Q47604204PTEN-L promotes type I interferon responses and antiviral immunity
Q33831408Palmitate has proapoptotic and proinflammatory effects on articular cartilage and synergizes with interleukin-1.
Q60947070Parasite Recognition and Signaling Mechanisms in Innate Immune Responses to Malaria
Q36553535Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells
Q38625740Parental exposure to bisphenol A and its analogs influences zebrafish offspring immunity
Q35032380Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans
Q36804679Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis
Q36784106Particulate adjuvant and innate immunity: past achievements, present findings, and future prospects
Q92011762Pathogenesis and Immune Response Caused by Vector-Borne and Other Viral Infections in a Tupaia Model
Q38750548Pathogenesis of Inflammatory Bowel Disease and Recent Advances in Biologic Therapies.
Q37264192Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell lines
Q26995283Pathogenesis of infection in surgical patients
Q26771860Pathophysiology of chronic rhinosinusitis, pharmaceutical therapy options
Q95841208Pattern Recognition Receptor Ligands as an Emerging Therapeutic Agent for Latent HIV-1 Infection
Q35927372Pattern Recognition Receptors in HIV Transmission
Q33358901Pattern recognition receptors and DNA repair: starting to put a jigsaw puzzle together
Q35363430Pattern recognition receptors in the gut: analysis of their expression along the intestinal tract and the crypt/villus axis
Q37728924Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance
Q35905385Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance
Q36086724Pellino-1 selectively regulates epithelial cell responses to rhinovirus.
Q36322355Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.
Q28513622Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
Q30700261Perioperative treatment with the new synthetic TLR-4 agonist GLA-SE reduces cancer metastasis without adverse effects
Q39425000Phagocytosis: A Fundamental Process in Immunity.
Q89551530Pharmacological Inhibition of Caspase-8 Suppresses Inflammation-Induced Angiogenesis in the Cornea
Q35312451Phenotypic, ultra-structural, and functional characterization of bovine peripheral blood dendritic cell subsets
Q59356542Phosphatase Cdc25A Negatively Regulates the Antiviral Immune Response by Inhibiting TBK1 Activity
Q64278393Phospholipid regulation of innate immunity and respiratory viral infection
Q34303351Phosphoproteomics combined with quantitative 14-3-3-affinity capture identifies SIRT1 and RAI as novel regulators of cytosolic double-stranded RNA recognition pathway.
Q38823721Physiological aspects of Toll-like receptor 4 activation in sepsis-induced acute kidney injury
Q40216716Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells.
Q26773952Plasmacytoid dendritic cells in allogeneic hematopoietic cell transplantation: benefit or burden?
Q35699010Plasmacytoid dendritic cells lead the charge against tumors
Q92405179Platelets in Sepsis: An Update on Experimental Models and Clinical Data
Q33404240Platelets in pulmonary vascular physiology and pathology
Q37690927Pneumonia, Acute Respiratory Distress Syndrome, and Early Immune-Modulator Therapy.
Q36098740Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5.
Q36476232Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia
Q38804315Poly(I:C) potentiates Bacillus Calmette-Guérin immunotherapy for bladder cancer
Q27001032Population genetic tools for dissecting innate immunity in humans
Q102063083Porcine haemagglutinating encephalomyelitis virus deactivates transcription factor IRF3 and limits type I interferon production
Q40102338Porcine parvovirus infection activates inflammatory cytokine production through Toll-like receptor 9 and NF-κB signaling pathways in porcine kidney cells
Q35607012Porous silicon microparticle potentiates anti-tumor immunity by enhancing cross-presentation and inducing type I interferon response
Q34298604Porphyromonas gingivalis exacerbates ligature-induced, RANKL-dependent alveolar bone resorption via differential regulation of Toll-like receptor 2 (TLR2) and TLR4.
Q44255321Porphyromonas gingivalis promotes neointimal formation after arterial injury through toll-like receptor 2 signaling
Q99238024Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4
Q35131335Positive feedback regulation of proliferation in vascular smooth muscle cells stimulated by lipopolysaccharide is mediated through the TLR 4/Rac1/Akt pathway.
Q60046861Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs
Q36048608Possible role of TLR4 and TLR9 SNPs in protection against congenital toxoplasmosis
Q38937786Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2 α
Q92648250Preclinical septic shock research: why we need an animal ICU
Q40156904Preexisting Salmonella-specific immunity interferes with the subsequent development of immune responses against the Salmonella strains delivering H9N2 hemagglutinin
Q36514286Presentation of phagocytosed antigens by MHC class I and II.
Q51737047Preterm Life in Sterile Conditions: A Study on Preterm, Germ-Free Piglets.
Q36906789Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci.
Q64071164Priming of HIV-1-specific CD8 T cells with strong functional properties from naïve T cells
Q37353574Prior TLR5 induction in human T cells results in a transient potentiation of subsequent TCR-induced cytokine production
Q38242452Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis
Q28534801Pro-inflammatory flagellin proteins of prevalent motile commensal bacteria are variably abundant in the intestinal microbiome of elderly humans
Q47551976Probiotics and Paraprobiotics in Viral Infection: Clinical Application and Effects on the Innate and Acquired Immune Systems
Q91940379Profiling and functional characterization of circulation LncRNAs that are associated with coronary atherosclerotic plaque stability
Q41870118Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration.
Q64232292Promising Recent Strategies with Potential Clinical Translational Value to Combat Antibacterial Resistant Surge
Q56977004Prospects in Innate Immune Responses as Potential Control Strategies against Non-Primate Lentiviruses
Q47258262Prostaglandin E2 as a Regulator of Immunity to Pathogens.
Q29620351Protective and pathogenic functions of macrophage subsets
Q36067731Protective role of Toll-like Receptor 3-induced type I interferon in murine coronavirus infection of macrophages.
Q49511036Protein Palmitoylation and Its Role in Bacterial and Viral Infections.
Q39233347Protein Tyrosine Phosphatases in Systemic Sclerosis: Potential Pathogenic Players and Therapeutic Targets.
Q28084032Protein kinase C in the immune system: from signalling to chromatin regulation
Q33728302Proteobacteria-specific IgA regulates maturation of the intestinal microbiota.
Q35988805Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes.
Q35249529Proteolytic disassembly of viral outer capsid proteins is crucial for reovirus-mediated type-I interferon induction in both reovirus-susceptible and reovirus-refractory tumor cells
Q33827807Punicalagin protects bovine endometrial epithelial cells against lipopolysaccharide-induced inflammatory injury
Q26797749Purinergic signaling and human immunodeficiency virus/acquired immune deficiency syndrome: From viral entry to therapy
Q28822592Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis
Q36611248Pyruvate Carboxylase Activates the RIG-I-like Receptor-Mediated Antiviral Immune Response by Targeting the MAVS signalosome
Q91935461RANKL blockade alleviates peri-implant bone loss and is enhanced by anti-inflammatory microRNA-146a through TLR2/4 signaling
Q59796823RIG-I Signaling via MAVS Is Dispensable for Survival in Lethal Influenza Infection
Q37687826RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection
Q41394269RIP2/RICK-dependent cytokine production upon Yersinia enterocolitica infection in macrophages with TLR4 deficiency
Q52593226RLRs and TLRs Signaling Pathways Cause Aberrant Production of Inflammatory Cytokines/Chemokines in an SFTSV Infection Mouse Model.
Q33790424RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events
Q26999252RNA mediated Toll-like receptor stimulation in health and disease
Q64105017RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection
Q38284081Radiation and inflammation
Q36083353Radiation takes its Toll
Q36005646Radiation, inflammation, and immune responses in cancer
Q37994838Recent advances in Toll-like receptors and anterior uveitis
Q24626339Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells
Q38061716Recent advances in understanding viral evasion of type I interferon
Q93204275Recent clinical trends in Toll-like receptor targeting therapeutics
Q38823065Recent progress in the development of Toll-like receptor (TLR) antagonists
Q37268198Receptor for advanced glycation endproducts signaling cascades are activated in pancreatic fibroblasts, but not in the INS1E insulinoma cell line: Are mesenchymal cells major players in chronic inflammation?
Q35163267Reciprocal regulation of reactive oxygen species and phospho-CREB regulates voltage gated calcium channel expression during Mycobacterium tuberculosis infection.
Q52608532Recognition of Double-Stranded RNA and Regulation of Interferon Pathway by Toll-Like Receptor 10.
Q38032312Recognition of bacterial infection by innate immune sensors
Q27010116Recognition of human oncogenic viruses by host pattern-recognition receptors
Q38081375Recognition of lipid A variants by the TLR4-MD-2 receptor complex
Q37925064Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity
Q38078138Recognition of pathogen-associated nucleic acids by endosomal nucleic acid-sensing toll-like receptors
Q34169579Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses
Q42337631Recombinant human annexin A5: a novel drug candidate for treatment of sepsis?
Q91582231Red Queen revisited: Immune gene diversity and parasite load in the asexual Poecilia formosa versus its sexual host species P. mexicana
Q41272014Red blood cell alloimmunization is influenced by the delay between Toll-like receptor agonist injection and transfusion.
Q38244572Redox regulation of inflammation: old elements, a new story
Q26849213Redox regulation of mitochondrial biogenesis
Q41074444Reduction of avian influenza virus shedding by administration of Toll-like receptor ligands to chickens
Q37590853Regular Voluntary Exercise Potentiates Interleukin-1β and Interleukin-18 Secretion by Increasing Caspase-1 Expression in Murine Macrophages.
Q47146914Regulation and Sensing of Inflammasomes and Their Impact on Intestinal Health
Q35920998Regulation of NF-κB by the CARD proteins
Q47550753Regulation of RIG-I Activation by K63-Linked Polyubiquitination
Q41977505Regulation of Toll-like receptor 4-mediated immune responses through Pasteurella multocida toxin-induced G protein signalling
Q38411808Regulation of immunity by Taeniids: lessons from animal models and in vitro studies
Q38223363Regulation of microRNA by hepatitis B virus infection and their possible association with control of innate immunity.
Q38042201Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers
Q38047077Regulators of innate immunity as novel targets for panviral therapeutics
Q57817927Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells
Q42115384Regulatory T cells in radiotherapeutic responses
Q42463251Regulatory role of PI3K-protein kinase B on the release of interleukin-1β in peritoneal macrophages from the ascites of cirrhotic patients.
Q45411446Reply: Moving forward in sepsis research
Q42357973Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses.
Q34819672Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production
Q97423592Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state
Q90886252Resolution of inflammation and mood disorders
Q38044665Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways
Q35194151Results of multicenter double-blind placebo-controlled phase II clinical trial of Panagen preparation to evaluate its leukostimulatory activity and formation of the adaptive immune response in patients with stage II-IV breast cancer
Q35136588Retromer promotes immune quiescence by suppressing Spätzle-Toll pathway in Drosophila
Q97529520Review on the Role of Host Immune Response in Protection and Immunopathogenesis during Cutaneous Leishmaniasis Infection
Q28828761Ribonuclease H1-dependent hepatotoxicity caused by locked nucleic acid-modified gapmer antisense oligonucleotides
Q91728183Robust induction of interferon and interferon-stimulated gene expression by influenza B/Yamagata lineage virus infection of A549 cells
Q38125198Role of CD14 in host protection against infections and in metabolism regulation.
Q38209327Role of Fused Mycobacterium tuberculosis Immunogens and Adjuvants in Modern Tuberculosis Vaccines.
Q90678746Role of Liver X Receptor in Mastitis Therapy and Regulation of Milk Fat Synthesis
Q35870208Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia
Q38240875Role of Toll-like receptors in Helicobacter pylori infection and immunity.
Q38544560Role of innate immune system in systemic sclerosis
Q26999064Role of innate immunity in neonatal infection
Q35027403Role of innate immunity in the pathogenesis of otitis media
Q21245486Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B
Q41346626Role of triggering receptor expressed on myeloid cells-1/3 in Klebsiella-derived pneumosepsis
Q37323336Role of yqiC in the Pathogenicity of Salmonella and Innate Immune Responses of Human Intestinal Epithelium
Q50045985Roles of HDACs in the Responses of Innate Immune Cells and as Targets in Inflammatory Diseases.
Q92854305Roles of Toll-Like Receptors in Nitroxidative Stress in Mammals
Q38232252Roles of cathelicidins in inflammation and bone loss
Q35746522SIV-infection-driven changes of pattern recognition receptor expression in mesenteric lymph nodes and gut microbiota dysbiosis
Q90814892SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association
Q35989436STAT1 deficiency redirects IFN signalling toward suppression of TLR response through a feedback activation of STAT3.
Q38579179STAT3: a critical component in the response to Helicobacter pylori infection.
Q63407933STING agonists activate latently infected cells and enhance SIV-specific responses ex vivo in naturally SIV controlled cynomolgus macaques
Q93088393STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus
Q49609103STING, DCs and the link between innate and adaptive tumor immunity.
Q36119950SUMO-Enriched Proteome for Drosophila Innate Immune Response
Q28552582Safety Assessment of Bacteroides uniformis CECT 7771 Isolated from Stools of Healthy Breast-Fed Infants
Q41951622Salivary histatin 3 inhibits heat shock cognate protein 70-mediated inflammatory cytokine production through toll-like receptors in human gingival fibroblasts
Q38219592Scale of health: indices of safety and efficacy in the evolving environment of large biological datasets
Q36357825Scavenger receptors target glycolipids for natural killer T cell activation
Q37258447Scavenging nucleic acid debris to combat autoimmunity and infectious disease
Q33554200Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding
Q34458906Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance
Q41770313Self-priming determines high type I IFN production by plasmacytoid dendritic cells
Q35361219Sensing of immature particles produced by dengue virus infected cells induces an antiviral response by plasmacytoid dendritic cells
Q37834944Sensing the enemy, containing the threat: cell-autonomous immunity to Chlamydia trachomatis
Q38419969Sequential Immune Responses: The Weapons of Immunity
Q35224597Sex differences in platelet toll-like receptors and their association with cardiovascular risk factors
Q89152500Short-Form Bomanins Mediate Humoral Immunity in Drosophila
Q64097047Short-chain Fatty Acids Inhibit Staphylococcal Lipoprotein-induced Nitric Oxide Production in Murine Macrophages
Q35784465Short-chain fatty acids induce pro-inflammatory cytokine production alone and in combination with toll-like receptor ligands
Q36343260Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity
Q26829757Siglecs as sensors of self in innate and adaptive immune responses
Q39236108Signaling Strategies of Malaria Parasite for Its Survival, Proliferation, and Infection during Erythrocytic Stage
Q91649408Silymarin inhibits Toll-like receptor 8 gene expression and apoptosis in Ramos cancer cell line
Q40235598Simian Immunodeficiency Virus Targeting of CXCR3+ CD4+ T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets.
Q44308797Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae.
Q42740986Single nucleotide polymorphisms in toll-like receptor genes and case-control association studies with bovine tuberculosis.
Q30539710Sisters in arms: myeloid and tubular epithelial cells shape renal innate immunity
Q26866098Skewed Helper T-Cell Responses to IL-12 Family Cytokines Produced by Antigen-Presenting Cells and the Genetic Background in Behcet's Disease
Q26769682Small Heterodimer Partner and Innate Immune Regulation
Q36012754Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation.
Q35051773Small molecule glutaminase inhibitors block glutamate release from stimulated microglia
Q40621223Soluble IL-6 Receptor and IL-27 Subunit p28 Protein Complex Mediate the Antiviral Response through the Type III IFN Pathway
Q38971847Soluble β-glucan from Grifola frondosa induces tumor regression in synergy with TLR9 agonist via dendritic cell-mediated immunity.
Q95315192Solute Carrier Family 37 Member 2 (SLC37A2) Negatively Regulates Murine Macrophage Inflammation by Controlling Glycolysis
Q41456346Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection
Q26861391Spinal interleukin-10 therapy to treat peripheral neuropathic pain
Q40478704Spleen contributes significantly to increased circulating levels of fibroblast growth factor 23 in response to lipopolysaccharide-induced inflammation.
Q40061204Splenic microRNA Expression Profiles and Integration Analyses Involved in Host Responses to Salmonella enteritidis Infection in Chickens.
Q39044882Spontaneous NF-κB activation by autocrine TNFα signaling: a computational analysis
Q52353653Src Family Kinases Regulate Interferon Regulatory Factor 1 K63 Ubiquitination following Activation by TLR7/8 Vaccine Adjuvant in Human Monocytes and B Cells.
Q26766421Staphylococcal Superantigens Spark Host-Mediated Danger Signals
Q64059286Staphylococcal Superantigens: Pyrogenic Toxins Induce Toxic Shock
Q57163788Staphylococcus aureus modulation of innate immune responses through Toll-like (TLR), (NOD)-like (NLR) and C-type lectin (CLR) receptors
Q38819131Statin pretreatment inhibits the lipopolysaccharide-induced epithelial-mesenchymal transition via the downregulation of toll-like receptor 4 and nuclear factor-κB in human biliary epithelial cells
Q38761791Stem and progenitor cell alterations in myelodysplastic syndromes
Q99631177Stimulus-specificity in the Responses of Immune Sentinel Cells
Q36627425Streptococcus pneumoniae Endopeptidase O (PepO) Elicits a Strong Innate Immune Response in Mice via TLR2 and TLR4 Signaling Pathways
Q89903049Streptococcus pneumoniae aminopeptidase N contributes to bacterial virulence and elicits a strong innate immune response through MAPK and PI3K/AKT signaling
Q47842696Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates
Q42424399Structure-Dependent Immune Modulatory Activity of Protegrin-1 Analogs.
Q49726907Structure-guided development of covalent TAK1 inhibitors.
Q91918184Subversion of host immune responses by otopathogens during otitis media
Q49723825Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production.
Q44519335Suppression of collagen-induced arthritis by intra-articular lentiviral vector-mediated delivery of Toll-like receptor 7 short hairpin RNA gene.
Q40101973Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1.
Q55475191Suppressor of IKKepsilon forms direct interactions with cytoskeletal proteins, tubulin and α‐actinin, linking innate immunity to the cytoskeleton.
Q92809462Surface Immunogenic Protein of Streptococcus Group B is an Agonist of Toll-Like Receptors 2 and 4 and a Potential Immune Adjuvant
Q37000243Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD.
Q41988798Synergistic effects of NOD1 or NOD2 and TLR4 activation on mouse sickness behavior in relation to immune and brain activity markers.
Q40460575Synergy between CD40 and MyD88 Does Not Influence Host Survival to Salmonella Infection
Q28085375Synthetic Nanoparticles for Vaccines and Immunotherapy
Q38072067Synthetic adjuvants for vaccine formulations: phytol derivatives
Q40280801Synthetic nanovaccines for immunotherapy.
Q37987289Systemic antibody responses to gut microbes in health and disease
Q27335125Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity
Q44133482T Helper 17 Promotes Induction of Antigen-Specific Gut-Mucosal Cytotoxic T Lymphocytes following Adenovirus Vector Vaccination
Q44048514T cell activation status determines the cytokine pattern induced by zymosan and bacterial DNA both in thymocytes and splenocytes
Q35667029T cell memory. Resident memory CD8 T cells trigger protective innate and adaptive immune responses
Q34171890T cell-macrophage interactions and granuloma formation in vasculitis.
Q36244299T lymphocytes and normal tissue responses to radiation
Q38767311TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1.
Q37745189TAK1 regulates resident macrophages by protecting lysosomal integrity
Q37162393TBK1 regulates prostate cancer dormancy through mTOR inhibition
Q38007258TH17 deficiency in human disease
Q40845561TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Mediates Antibacterial Defense during Gram-Negative Pneumonia by Inducing Interferon-x03B3.
Q37223021TLR Signalling Pathways Diverge in Their Ability to Induce PGE2.
Q30532238TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis.
Q38038940TLR signaling and DNA repair: are they associated?
Q34576048TLR-9 contributes to the antiviral innate immune sensing of rodent parvoviruses MVMp and H-1PV by normal human immune cells
Q38218114TLR-CD40 Cross-Talk in Anti-Leishmanial Immune Response
Q38887103TLR-induced activation of neutrophils promotes histamine production via a PI3 kinase dependent mechanism.
Q49551434TLR-induced secretion of novel cytokine IL-27 is defective in newly diagnosed type-2 diabetic subjects.
Q28586721TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification
Q64896109TLR2 Expression on Leukemic B Cells from Patients with Chronic Lymphocytic Leukemia.
Q91415313TLR2 and NODs1 and 2 cooperate in inflammatory responses associated with renal ischemia reperfusion injury
Q38172423TLR2 and TLR4 in autoimmune diseases: a comprehensive review
Q41810950TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro
Q35069416TLR2 ligands induce NF-κB activation from endosomal compartments of human monocytes
Q92512760TLR2 polymorphism (rs650082970) is associated with somatic cell count in goat milk
Q34936998TLR2, TLR4 and the MyD88 signaling are crucial for the in vivo generation and the longevity of long-lived antibody-secreting cells
Q35972372TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair
Q28353960TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology
Q36675252TLR3 immunity to infection in mice and humans
Q35800442TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection
Q36976363TLR3-induced placental miR-210 down-regulates the STAT6/interleukin-4 pathway
Q94545415TLR4 Cross-Talk With NLRP3 Inflammasome and Complement Signaling Pathways in Alzheimer's Disease
Q41593236TLR4 interaction with LPS in glioma CD133+ cancer stem cells induces cell proliferation, resistance to chemotherapy and evasion from cytotoxic T lymphocyte-induced cytolysis
Q38975045TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a
Q42122613TLR4/IFNγ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models
Q90680821TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease
Q92239398TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner
Q42199467TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7.
Q40082187TLR8 Couples SOCS-1 and Restrains TLR7-Mediated Antiviral Immunity, Exacerbating West Nile Virus Infection in Mice
Q93221565TLR8 and its endogenous ligand miR-21 contribute to neuropathic pain in murine DRG
Q47656395TLR8 combined withTLR3 or TLR4 agonists enhances DC-NK driven effector Tc1 cells
Q27026056TLR8: the forgotten relative revindicated
Q55399332TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons.
Q91838076TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes
Q35936144TLR9 and MyD88 are crucial for the development of protective immunity to malaria
Q36350923TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN.
Q36162455TLR9 is important for protection against intestinal damage and for intestinal repair
Q27300986TLR9-dependent and independent pathways drive activation of the immune system by Propionibacterium acnes
Q92123390TLRs in pulmonary diseases
Q34546515TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury
Q41844903TRIF mediates Toll-like receptor 2-dependent inflammatory responses to Borrelia burgdorferi
Q49223631TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing.
Q40118447TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF-TBK1 Interaction
Q38935940TRPM4 expression is associated with activated B cell subtype and poor survival in diffuse large B cell lymphoma
Q36712941Taming lupus-a new understanding of pathogenesis is leading to clinical advances
Q27342059Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis
Q99594459Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
Q38296340Targeting defective Toll-like receptor-3 function and idiopathic pulmonary fibrosis
Q37370733Targeting inflammasome/IL-1 pathways for cancer immunotherapy
Q48055643Targeting innate immunity for treatment of type 1 diabetes
Q33739020Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes
Q35176207Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer
Q92753898Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives
Q89451828Targeting toll-like receptor 4 signalling pathways: can therapeutics pay the toll for hypertension?
Q27010345Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases
Q64054757Techniques for Studying Decoding of Single Cell Dynamics
Q47260413Teleost-Specific TLR19 Localizes to Endosome, Recognizes dsRNA, Recruits TRIF, Triggers both IFN and NF-κB Pathways, and Protects Cells from Grass Carp Reovirus Infection
Q38813798The Arabidopsis PEPR pathway couples local and systemic plant immunity.
Q36941406The Balance between Conventional DCs and Plasmacytoid DCs Is Pivotal for Immunological Tolerance during Pregnancy in the Mouse
Q94398601The Biologic Response to Bearing Materials
Q42953049The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation
Q92650642The Challenge of Teaching Essential Immunology Laboratory Skills to Undergraduates in One Month-Experience of an Osteoimmunology Course on TLR Activation
Q37672847The Combination of MBP and BCG-Induced Dendritic Cell Maturation through TLR2/TLR4 Promotes Th1 Activation In Vitro and Vivo.
Q55134544The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome.
Q36300913The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.
Q37677971The Expression of Toll-Like Receptors in Patients with B-Cell Chronic Lymphocytic Leukemia.
Q36248293The Fab Fragment of a Human Anti-Siglec-9 Monoclonal Antibody Suppresses LPS-Induced Inflammatory Responses in Human Macrophages
Q38771520The Increased Expression of Toll-Like Receptor 4 in Renal and Skin Lesions in Lupus Erythematosus
Q90421576The Inhibitory Role of M2000 (β-D-Mannuronic Acid) on Expression of Toll-like Receptor 2 and 4 in HT29 Cell Line
Q64268511The Interaction Between Two Worlds: MicroRNAs and Toll-Like Receptors
Q43042897The Interactive Roles of Lipopolysaccharides and dsRNA/Viruses on Respiratory Epithelial Cells and Dendritic Cells in Allergic Respiratory Disorders: The Hygiene Hypothesis.
Q46412915The Intra-Dependence of Viruses and the Holobiont.
Q30855831The Lung is a Host Defense Niche for Immediate Neutrophil-Mediated Vascular Protection.
Q29615845The M1 and M2 paradigm of macrophage activation: time for reassessment
Q59793198The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus
Q66678832The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation
Q36102645The Microbiome and Immune Regulation After Transplantation
Q40355343The Molecular Basis for the Lack of Inflammatory Responses in Mouse Embryonic Stem Cells and Their Differentiated Cells.
Q37653873The Novel Toll-Like Receptor 2 Agonist SUP3 Enhances Antigen Presentation and T Cell Activation by Dendritic Cells.
Q36980637The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Q48332393The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis.
Q40237948The R753Q polymorphism in Toll-like receptor 2 (TLR2) attenuates innate immune responses to mycobacteria and impairs MyD88 adapter recruitment to TLR2.
Q42047850The RIG-I ATPase core has evolved a functional requirement for allosteric stabilization by the Pincer domain
Q36665778The RNA-binding protein Mex3B is a coreceptor of Toll-like receptor 3 in innate antiviral response
Q54322910The RP105/MD-1 complex is indispensable for TLR4/MD-2-dependent proliferation and IgM-secreting plasma cell differentiation of marginal zone B cells.
Q64250654The Relationship between Toll-like Receptors and -Related Gastropathies: Still a Controversial Topic
Q32183747The Role of Caveolin 1 in HIV Infection and Pathogenesis
Q39761927The Role of Lipopolysaccharide Structure in Monocyte Activation and Cytokine Secretion
Q95840732The Role of Microbiomes in Pregnant Women and Offspring: Research Progress of Recent Years
Q48093735The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and Cancer.
Q38962174The Role of Phagocytes and NETs in Dermatophytosis.
Q52632607The Role of Toll-Like Receptor Signaling in the Progression of Heart Failure.
Q57170572The Role of Toll-Like Receptor in Inflammation and Tumor Immunity
Q38860235The Roles of Type I Interferon in Bacterial Infection
Q92025114The Roles of the Gut Microbiota and Toll-like Receptors in Obesity and Nonalcoholic Fatty Liver Disease
Q26744559The Scavenger Receptor SREC-I Cooperates with Toll-Like Receptors to Trigger Inflammatory Innate Immune Responses
Q35665940The TLR4-TRIF pathway protects against H5N1 influenza virus infection
Q41915308The TLR7 agonist imiquimod induces bronchodilation via a nonneuronal TLR7-independent mechanism: a possible role for quinoline in airway dilation
Q38043290The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation
Q37662888The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin
Q36771989The Toll-like receptor 5 agonist entolimod suppresses hepatic metastases in a murine model of ocular melanoma via an NK cell-dependent mechanism
Q40076047The Us2 Gene Product of Herpes Simplex Virus 2 modulates NF-κB activation by targeting TAK1.
Q91890884The activation of bystander CD8+ T cells and their roles in viral infection
Q99241373The adaptor protein CARD9, from fungal immunity to tumorigenesis
Q27329515The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria
Q36862843The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation
Q38594314The blood-epididymis barrier and inflammation
Q26825196The clinical relevance of animal models in Sjögren's syndrome: the interferon signature from mouse to man
Q55338907The crucial roles of inflammatory mediators in inflammation: A review.
Q26796274The cytoskeleton in cell-autonomous immunity: structural determinants of host defence
Q33757762The early activation of CD8+ T cells is dependent on type I IFN signaling following intramuscular vaccination of adenovirus vector
Q27001581The effects of TLR activation on T-cell development and differentiation
Q59351013The endosomal Toll-like receptors 7 and 9 cooperate in detection of MHV68 infection
Q35399068The epithelial αvβ3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components
Q48344332The evolutionary characteristics and structural biology of Gallus toll-like receptor 21.
Q90590486The expanding landscape of inflammatory cells affecting cancer therapy
Q34553478The expression of Toll-like receptors and development of severe sepsis in patients with acute myeloid leukemias after induction chemotherapy
Q35187597The flagellar regulator TviA reduces pyroptosis by Salmonella enterica serovar Typhi
Q38097500The genetics of innate immunity sensors and human disease
Q35126599The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) production
Q37042237The host STING pathway at the interface of cancer and immunity
Q33934251The human long noncoding RNA lnc-IL7R regulates the inflammatory response
Q27026072The immune system as a sensor of the metabolic state
Q34871440The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.
Q27022093The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response, and regulatory T cells
Q42781164The impact of HIV infection on blood leukocyte responsiveness to bacterial stimulation in asymptomatic patients and patients with bloodstream infection
Q38013050The impact of infection and tissue damage in solid-organ transplantation
Q58264156The inflammation regulation effects ofEnterococcus faeciumHDRsEf1 on human enterocyte-like HT-29 cells
Q64945497The inflammatory function of human IgA.
Q38981754The inflammatory response triggered by Influenza virus: a two edged sword.
Q47553695The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.
Q48255915The islet-resident macrophage is in an inflammatory state and senses microbial products in blood.
Q34991453The level of viral infection of antigen-presenting cells correlates with the level of development of Theiler's murine encephalomyelitis virus-induced demyelinating disease
Q37345920The life cycle stages of Pneumocystis murina have opposing effects on the immune response to this opportunistic, fungal pathogen.
Q38013042The mammalian secreted RNases: mechanisms of action in host defence.
Q37249246The many faces of C/EBPδ and their relevance for inflammation and cancer
Q37495470The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids
Q35170799The microbiota, the immune system and the allograft
Q38727480The molecular mechanisms of TLR-signaling cooperation in cytokine regulation
Q42140878The molecular pathways underlying host resistance and tolerance to pathogens
Q36731249The multifaceted biology of plasmacytoid dendritic cells
Q41872019The nature of activatory and tolerogenic dendritic cell-derived signal 2.
Q38020956The neuroendocrine control of the innate immune system in health and brain diseases
Q52725381The non-haemostatic role of platelets in systemic lupus erythematosus.
Q33601748The peripheral blood proteome signature of idiopathic pulmonary fibrosis is distinct from normal and is associated with novel immunological processes
Q35564597The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice
Q38824186The potential of intravenous immunoglobulins for cancer therapy: a road that is worth taking?
Q36054671The potential of mesenchymal stromal cells as a novel cellular therapy for multiple sclerosis
Q42217334The rapid and sustained responses of dendritic cells to influenza virus infection in a non-human primate model.
Q38867621The regulation of inflammation by oxidized phospholipids
Q37583908The role of NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection
Q89700559The role of TLRs in cervical cancer with HPV infection: a review
Q38072995The role of cysteine proteinases and their inhibitors in the host-pathogen cross talk
Q33662836The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: are there opportunities to intervene?
Q34636651The role of flagella and chemotaxis genes in host pathogen interaction of the host adapted Salmonella enterica serovar Dublin compared to the broad host range serovar S. Typhimurium.
Q38056731The role of innate immune signals in immunity to Brucella abortus
Q94476127The role of innate immunity in the long-term outcome of lung transplantation
Q24599103The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use
Q26827408The role of macrophages and dendritic cells in the initiation of inflammation in IBD
Q36147431The role of pattern recognition receptors in the innate recognition of Candida albicans
Q26861263The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
Q38665495The role of toll-like receptors in B-cell development and immunopathogenesis of common variable immunodeficiency
Q35189391The stimulatory activity of plasma in patients with advanced non-small cell lung cancer requires TLR-stimulating nucleic acid immunoglobulin complexes and discriminates responsiveness to chemotherapy
Q33743861The stress granule component TIA-1 binds tick-borne encephalitis virus RNA and is recruited to perinuclear sites of viral replication to inhibit viral translation
Q54299597The suppression of TRIM21 and the accumulation of IFN-α play crucial roles in the pathogenesis of osteonecrosis of the femoral head.
Q93174792The tracking of lipopolysaccharide through the feto-maternal compartment and the involvement of maternal TLR4 in inflammation-induced fetal brain injury
Q35608944The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells
Q34364408The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis
Q27010599The translocation of nuclear molecules during inflammation and cell death
Q38809889The tumor suppressor PTEN has a critical role in antiviral innate immunity
Q33802952The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.
Q52558842The ubiquitin proteasome system as a potential therapeutic target for systemic sclerosis.
Q39199678The viral innate immune antagonism and an alternative vaccine design for PRRS virus
Q92460972The zinc-finger protein ZFYVE1 modulates TLR3-mediated signaling by facilitating TLR3 ligand binding
Q92757837Therapeutic Effect of Bifidobacterium Administration on Experimental Autoimmune Myasthenia Gravis in Lewis Rats
Q35683589Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis
Q26863283Therapeutic cancer vaccines: past, present, and future
Q39223774Therapeutic factor VIII does not trigger TLR1.2 and TLR2.6 signalling in vitro.
Q37991391Therapeutic modulation of miRNA for the treatment of proinflammatory lung diseases.
Q38881534Therapeutic targeting of Toll-like receptors: a review of Toll-like receptors and their signaling pathways in psoriasis
Q89495031Thoroughly Remold the Localization and Signaling Pathway of TLR22
Q59353365Three Main Inducers of Alphacoronavirus Infection of Enterocytes: Sialic Acid, Proteases, and Low pH
Q54207308Tissue expression of Toll-like receptors 2, 3, 4 and 7 in swine in response to the Shimen strain of classical swine fever virus.
Q38003021Tissue microenvironments define and get reinforced by macrophage phenotypes in homeostasis or during inflammation, repair and fibrosis.
Q35953024Tissue-specific mRNA expression profiles of porcine Toll-like receptors at different ages in germ-free and conventional pigs
Q38068399Tissues use resident dendritic cells and macrophages to maintain homeostasis and to regain homeostasis upon tissue injury: the immunoregulatory role of changing tissue environments.
Q40104707To Eat and to Be Eaten: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon Infection
Q89259174Toll-Like Receptor 4 (TLR4) Stimulates Synovial Injury of Temporomandibular Joint in Rats Through the Activation of p38 Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway
Q39016015Toll-Like Receptor 4 Signaling in High Mobility Group Box-1 Protein 1 Mediated the Suppression of Regulatory T-Cells
Q35745585Toll-Like Receptor 9-Mediated Inflammation Triggers Alveolar Bone Loss in Experimental Murine Periodontitis
Q38357504Toll-Like Receptor Pathways in Autoimmune Diseases
Q55516319Toll-Like Receptor-1 Single-Nucleotide Polymorphism 1805T/G Is Associated With Predisposition to Multibacillary Tuberculosis.
Q90026735Toll-Like Receptor-4 Antagonist (+)-Naloxone Confers Sexually Dimorphic Protection From Inflammation-Induced Fetal Programming in Mice
Q47095125Toll-Like Receptor-4 Signaling Drives Persistent Fibroblast Activation and Prevents Fibrosis Resolution in Scleroderma
Q37451783Toll-Like Receptor-Mediated Free Radical Generation in Clonorchis sinensis Excretory-Secretory Product-Treated Cholangiocarcinoma Cells
Q28817791Toll-Like Receptors 2 and 4 Cooperate in the Control of the Emerging Pathogen Brucella microti
Q33978723Toll-Like Receptors and Cancer: MYD88 Mutation and Inflammation.
Q93080297Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods
Q37669879Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice
Q50351017Toll-like Receptor 1/2 Agonist Pam3CSK4 Suppresses Lipopolysaccharide-driven IgG1 Production while Enhancing IgG2a Production by B Cells.
Q36208611Toll-like Receptor 10 in Helicobacter pylori Infection
Q38042942Toll-like Receptors in Chronic Lymphocytic Leukemia
Q34730338Toll-like receptor -1, -2, and -6 polymorphisms and pulmonary tuberculosis susceptibility: a systematic review and meta-analysis
Q37640854Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection
Q47135862Toll-like receptor 2 has a prominent but nonessential role in innate immunity to Staphylococcus aureus pneumonia
Q37596779Toll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathology.
Q36685148Toll-like receptor 2 mediates peripheral nerve injury-induced NADPH oxidase 2 expression in spinal cord microglia
Q38450410Toll-like receptor 3 (TLR3) and the development of type 1 diabetes mellitus.
Q90504963Toll-like receptor 3 activation increases voluntary alcohol intake in C57BL/6J male mice
Q90504943Toll-like receptor 3 dynamics in female C57BL/6J mice: Regulation of alcohol intake
Q41132115Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome
Q95514665Toll-like receptor 3 increases allergic and irritant contact dermatitis
Q37312225Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.
Q35792017Toll-like receptor 4 gene polymorphism is associated with chronic periodontitis
Q26795837Toll-like receptor 4 gene polymorphisms and susceptibility to colorectal cancer: a meta-analysis and review
Q40659533Toll-like receptor 4 signaling has a critical role in Porphyromonas gingivalis-accelerated neointimal formation after arterial injury in mice
Q40715928Toll-like receptor 9 regulates melanogenesis through NF-κB activation
Q35420431Toll-like receptor activation by helminths or helminth products to alleviate inflammatory bowel disease
Q38181176Toll-like receptor agonists: a patent review (2011 - 2013).
Q39061492Toll-like receptor genetic variants and colorectal cancer.
Q30620402Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.
Q37139589Toll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer
Q38173600Toll-like receptor regulation of intestinal development and inflammation in the pathogenesis of necrotizing enterocolitis
Q38432017Toll-like receptor signaling in parasitic infections.
Q38259564Toll-like receptor signaling pathways
Q37568467Toll-like receptor signaling regulates cisplatin-induced mechanical allodynia in mice
Q28589300Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis
Q38973178Toll-like receptors -4 and -5 in oral and cutaneous squamous cell carcinomas
Q54338198Toll-like receptors 2 and 4 mediate the capacity of mesenchymal stromal cells to support the proliferation and differentiation of CD34⁺ cells.
Q38832613Toll-like receptors and chronic inflammation in rheumatic diseases: new developments
Q51731647Toll-like receptors and cytokines in the brain and in spleen of dogs with visceral leishmaniosis.
Q43075865Toll-like receptors and their role in persistent pain
Q48118332Toll-like receptors elicit different recruitment kinetics of monocytes and neutrophils in mouse acute inflammation
Q27011462Toll-like receptors in antiviral innate immunity
Q53687316Toll-like receptors in immunity and inflammatory diseases: Past, present, and future.
Q38004493Toll-like receptors in leishmania infections: guardians or promoters?
Q37295411Toll-like receptors in prostate infection and cancer between bench and bedside
Q27010697Toll-like receptors in the host defense against Pseudomonas aeruginosa respiratory infection and cystic fibrosis
Q38131726Toll-like receptors in urothelial cells--targets for cancer immunotherapy
Q45207411Toll-like receptors promote inflammation in idiopathic inflammatory myopathies
Q37114498Toll-like receptors, triggering receptor expressed on myeloid cells family members and receptor for advanced glycation end-products in allergic airway inflammation
Q40905712Toll/IL-1 domain-containing adaptor inducing IFN-β (TRIF) mediates innate immune responses in murine peritoneal mesothelial cells through TLR3 and TLR4 stimulation
Q38245843Towards identifying novel anti-Eimeria agents: trace elements, vitamins, and plant-based natural products
Q47557198Towards the Application of Human Defensins as Antivirals
Q34742189Transcription analysis of the porcine alveolar macrophage response to porcine circovirus type 2.
Q34984258Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages
Q35631352Transcriptional Profiling of Host Gene Expression in Chicken Embryo Fibroblasts Infected with Reticuloendotheliosis Virus Strain HA1101.
Q90222416Transcriptional and chromatin regulation in interferon and innate antiviral gene expression
Q37977719Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes
Q34390332Transcriptional specialization of human dendritic cell subsets in response to microbial vaccines
Q92700295Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation
Q28504683Transepithelial migration of neutrophils into the lung requires TREM-1
Q57240408Translational Modeling of Antibacterial Agents
Q55510563Trauma-Induced Damage-Associated Molecular Patterns-Mediated Remote Organ Injury and Immunosuppression in the Acutely Ill Patient.
Q28067939Trial Watch: Immunostimulation with Toll-like receptor agonists in cancer therapy
Q57394699Trial Watch: Toll-like receptor agonists in cancer immunotherapy
Q33878578Trial Watch: Toll-like receptor agonists in oncological indications
Q43676807Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia
Q36302384Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-κB Pathways along with TNFR-Associated Factor 6
Q35585775Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination
Q37603408True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity
Q54206838Ts-Hsp70 induces protective immunity against Trichinella spiralis infection in mouse by activating dendritic cells through TLR2 and TLR4.
Q54570539Turning on the Lights inside Neutrophils.
Q38109656Tying the knot between cytokine and toll-like receptor signaling in gastrointestinal tract cancers.
Q38004932Type I IFN-mediated regulation of IL-1 production in inflammatory disorders.
Q37691992Type I Interferons as Regulators of Lung Inflammation
Q47138467Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences
Q39083884Type I interferon and NF-κB activation elicited by herpes simplex virus gH/gL via αvβ3 integrin in epithelial and neuronal cell lines
Q37114475Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensis live vaccine strain
Q38008369Type I interferons as ambiguous modulators of chronic inflammation in the central nervous system
Q34585998Type-I interferon is critical for FasL expression on lung cells to determine the severity of influenza
Q34039427Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.
Q26828015Tyrosine phosphorylation in Toll-like receptor signaling
Q89575106USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I
Q41834681Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response
Q49165915Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3.
Q34786031Ubiquitination of ECSIT is crucial for the activation of p65/p50 NF-κBs in Toll-like receptor 4 signaling
Q37143150Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex
Q35211600Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis
Q38212817Unconventional post-translational modifications in immunological signaling
Q35187585Uncoupling of pro- and anti-inflammatory properties of Staphylococcus aureus.
Q33953902Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils
Q34120040Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants
Q90726349Unmethylated CpG motif-containing genomic DNA fragment of Bacillus calmette-guerin promotes macrophage functions through TLR9-mediated activation of NF-κB and MAPKs signaling pathways
Q42487710Upregulation of Intestinal Mucin Expression by the Probiotic Bacterium E. coli Nissle 1917.
Q40193652Urban-rural differences in the gene expression profiles of Ghanaian children
Q59811551Use of next generation sequencing to investigate the microbiota of experimentally induced wounds and the effect of bandaging in horses
Q35498054Using Poly I:C as an adjuvant does not induce or exacerbate models of systemic lupus erythematosus
Q38916829Utilization of different anti-viral mechanisms by mammalian embryonic stem cells and differentiated cells
Q86509911VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis
Q48244778VEGF Requires the Receptor NRP-1 To Inhibit Lipopolysaccharide-Dependent Dendritic Cell Maturation.
Q55035385Validation of immunomodulatory effects of lipopolysaccharide through expression profiling of Th1 and Th2 biased genes in Newcastle disease virus vaccinated indigenous chicken.
Q40138819Variants in the non-coding region of the TLR2 gene associated with infectious subphenotypes in pediatric sickle cell anemia.
Q36827455Venezuelan equine encephalitis replicon particles can induce rapid protection against foot-and-mouth disease virus
Q35033144Viral immune evasion in dengue: toward evidence-based revisions of clinical practice guidelines
Q36456487Virotherapy, gene transfer and immunostimulatory monoclonal antibodies.
Q42261943Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING.
Q38626676Visual detection of Flavivirus RNA in living cells
Q35168069Visualizing toll-like receptor-dependent phagosomal dynamics in murine dendritic cells using live cell microscopy.
Q85084971Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation
Q24321402WDFY1 mediates TLR3/4 signaling by recruiting TRIF
Q85521723WITHDRAWN: Smurf2 negatively regulates IFN-á production through mediating IRF3 ubiquitination and degradation
Q36366663West Nile Virus Challenge Alters the Transcription Profiles of Innate Immune Genes in Rabbit Peripheral Blood Mononuclear Cells
Q26827754When ubiquitin meets NF-κB: a trove for anti-cancer drug development
Q92590052Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory disease
Q39020471Yeast virus-derived stimulator of the innate immune system augments the efficacy of virus vector-based immunotherapy.
Q90057880ZCCHC3 modulates TLR3-mediated signaling by promoting recruitment of TRIF to TLR3
Q64056313at Host Barrier Sites: Pattern Recognition Receptors and Beyond
Q33711685mRNA vaccine delivery using lipid nanoparticles
Q83227320macrophages switch to aerobic glycolysis to mount effective antibacterial defense
Q88911796miRNAs reshape immunity and inflammatory responses in bacterial infection
Q64064153pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG
Q36438385αvβ3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
Q48252525β-Arrestin 2 mediates the anti-inflammatory effects of fluoxetine in lipopolysaccharide-stimulated microglial cells
Q37578793β-arrestin protects neurons by mediating endogenous opioid arrest of inflammatory microglia

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