Cellular and molecular regulation of innate inflammatory responses

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Cellular and molecular regulation of innate inflammatory responses is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1034560344
P356DOI10.1038/CMI.2016.58
P932PMC publication ID5101451
P698PubMed publication ID27818489

P2093author name stringXuetao Cao
Juan Liu
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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathwayQ24306635
NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathwaysQ24309046
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune responseQ24317784
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASCQ24319706
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasomeQ24319799
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cellsQ24616649
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesQ24617969
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced deathQ24644712
Innate cell communication kick-starts pathogen-specific immunityQ26752790
Ubiquitin in the activation and attenuation of innate antiviral immunityQ26771789
Molecular mechanisms regulating NLRP3 inflammasome activationQ26778556
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Regulation of inflammasome signalingQ26996605
Measles virus hemagglutinin triggers intracellular signaling in CD150-expressing dendritic cells and inhibits immune responseQ37402444
Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice.Q37616722
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.Q37686404
Responses to LPS boost effector CD8 T-cell accumulation outside of signals 1 and 2.Q37714634
The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation.Q37733779
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Inflammasomes: far beyond inflammationQ37995069
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K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascadeQ38209104
Noncoding RNA and its associated proteins as regulatory elements of the immune system.Q38212814
Post-transcriptional coordination of immunological responses by RNA-binding proteins.Q38212815
Translational control of immune responses: from transcripts to translatomesQ38212816
Unconventional post-translational modifications in immunological signalingQ38212817
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Neutrophils at workQ38221176
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Dissecting the dendritic cell controversy in chronic hepatitis B virus infectionQ38264371
Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responsesQ38270733
The development and function of lung-resident macrophages and dendritic cells.Q38293022
IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity.Q51530407
A new receptor for LPSQ58379816
ILCs in the zoneQ58859200
Negative regulation of the type I interferon signaling pathway by synthetic Toll-like receptor 7 ligandsQ84025081
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responsesQ84174846
Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161Q84933191
Inflammatory ILC2 cells: disguising themselves as progenitors?Q86545431
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Control of adaptive immunity by the innate immune systemQ27026513
Respiratory epithelial cells orchestrate pulmonary innate immunityQ27687743
Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammationQ27700060
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA virusesQ27860455
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphatesQ27861007
Pattern recognition receptors and inflammationQ27861115
Homeostasis, inflammation, and disease susceptibilityQ28082739
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNAQ28118718
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory responseQ28242527
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammationQ28242537
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA virusesQ28391800
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signalingQ28505592
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogensQ28506322
Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20Q28508566
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune responseQ28510485
Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitisQ28511027
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathwaysQ28512993
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responsesQ28588300
The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptorsQ28589455
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathwaysQ28590675
Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activationQ28593417
NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STINGQ28975619
Toll-like receptors and their crosstalk with other innate receptors in infection and immunityQ29547722
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entryQ29615618
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responsesQ29616349
Inflammasomes in health and diseaseQ29616356
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acidQ29620015
Inefficient star formation in extremely metal poor galaxiesQ30303093
Single-cell technologies for monitoring immune systems.Q33692199
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritisQ34020424
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritisQ34020795
NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKKQ34027440
Inflammatory caspases are innate immune receptors for intracellular LPS.Q34041730
Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammationQ36767470
Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.Q36801851
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and toleranceQ36814061
NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.Q36863162
Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteriaQ36977474
G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell programQ37047314
Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellinQ37101139
NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammationQ37101151
NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4.Q37139809
Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infectionQ37178981
RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradationQ37213780
Long noncoding RNA #32 contributes to antiviral responses by controlling interferon-stimulated gene expressionQ37264066
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological toleranceQ38298765
The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells.Q38309617
The biology of innate lymphoid cellsQ38319907
IL-6 as a keystone cytokine in health and diseaseQ38433045
Guarding the frontiers: the biology of type III interferonsQ38550956
Regulatory dendritic cells in autoimmunity: A comprehensive reviewQ38563066
Autophagy and autophagy-related proteins in the immune systemQ38588827
NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutationsQ38750753
The tumor suppressor PTEN has a critical role in antiviral innate immunityQ38809889
Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis.Q38872144
Post-Translational Modification Control of Innate ImmunityQ38903391
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.Q38946818
Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β productionQ39000597
Identification of a role for TRIM29 in the control of innate immunity in the respiratory tractQ39330212
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathwayQ39706057
Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunityQ39725913
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta productionQ39774272
Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cellsQ40382473
Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis.Q40466317
The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formationQ40567547
iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.Q40610046
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensingQ40875210
The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathwaysQ40883748
Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cellsQ40899547
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicidaQ41429405
Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infectionQ41456346
A lectin S-domain receptor kinase mediates lipopolysaccharide sensing in Arabidopsis thaliana.Q41456359
The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6.Q41509672
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasomeQ41574826
Skin DCs cluster for efficient T cell activationQ41695487
TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitroQ41810950
Neutrophil sensing of cytoplasmic, pathogenic DNA in a cGAS-STING-independent mannerQ41971091
Reading the fine print: sequence-specific activation of cGAS.Q42121451
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.Q42135532
Rad50 and CARD9, missing links in cytosolic DNA-stimulated inflammationQ42217876
POP goes the inflammasome.Q42230412
A new RIDDle in DC-mediated cross-presentationQ42914308
Differential expression of the fractalkine chemokine receptor (CX3CR1) in human monocytes during differentiationQ43083885
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.Q43141233
Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO.Q45718626
High-dimensional analysis of the murine myeloid cell system.Q45956087
Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentationQ46090866
ILC development: TCF-1 reporting in.Q46138283
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonistsQ46602287
De-Mst-ifying microbicidal killingQ46651751
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talinQ46697060
Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow.Q47687570
Drosha cuts the tethers of myelopoiesisQ48117535
The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodesQ48309599
Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin.Q50779921
A PTENtial cause for the selectivity of oncolytic viruses?Q50896873
Corrigendum: Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract.Q51419414
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.Q34152180
Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10.Q34155771
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACEQ34247194
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSQ34247201
TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentationQ34416204
Immune cells in term and preterm laborQ34455630
Coordinated binding of NF-kappaB family members in the response of human cells to lipopolysaccharide.Q34509419
NLRX1 is a regulator of mitochondrial antiviral immunityQ34737001
IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells.Q34979676
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.Q35060864
Unifying immunology with informatics and multiscale biology.Q35134186
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activationQ35173133
Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsetsQ35213159
Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signalingQ35474544
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infectionQ35528340
The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitorQ35629731
Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competitionQ35629787
Intratumoral dendritic cells in the anti-tumor immune responseQ35833610
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.Q35866588
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virusQ35872309
Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosusQ35881985
Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING.Q35895670
Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell InteractionsQ36054488
TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow.Q36074418
Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infectionQ36108222
Runx3 specifies lineage commitment of innate lymphoid cellsQ36199803
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activityQ36200269
Neutrophil transcriptional profile changes during transit from bone marrow to sites of inflammationQ36302843
Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cellsQ36332123
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNAQ36345491
Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cellsQ36363466
Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responsesQ36389520
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6Q36420383
A new mouse strain for the analysis of invariant NKT cell functionQ36458138
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)711-721
P577publication date2016-11-01
P1433published inCellular and Molecular ImmunologyQ26842256
P1476titleCellular and molecular regulation of innate inflammatory responses
P478volume13

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