Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

scientific article

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.3268
P932PMC publication ID4618176
P698PubMed publication ID26414765
P5875ResearchGate publication ID282514854

P50authorDawang ZhouQ37382920
Terytty Yang LiQ42325546
Lanfen ChenQ56678878
Rongbin ZhouQ88031906
P2093author name stringChangchuan Xie
Hao Zhao
Jiahuai Han
Ping Wang
Joseph Avruch
Hong-Rui Wang
Sheng-Cai Lin
Xun Li
Jing Geng
Qinghua Chen
Kun-Yi Chien
Xiaozhen Wang
Randy L Johnson
Xiufeng Sun
Hongtan Wu
Shihao Zhang
Siyang Song
Lixin Hong
Qingxu Liu
Jinjia Zhang
Mingting Jiang
P2860cites workThe E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1Q24294840
Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesionQ24299123
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1Q24307232
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferationQ24308682
The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domainQ24311997
Cloning and characterization of a human protein kinase with homology to Ste20Q24337168
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life spanQ24338599
The hippo signaling pathway in development and cancerQ24603986
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutationQ24678428
The role of ubiquitylation in immune defence and pathogen evasionQ26860775
The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatmentQ27025661
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiologyQ27860991
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species productionQ28139177
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiencyQ28144652
Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPaseQ28269266
The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell deathQ28579594
NOX enzymes and the biology of reactive oxygenQ29547517
Toll-like receptors and their crosstalk with other innate receptors in infection and immunityQ29547722
Physiological roles of mitochondrial reactive oxygen speciesQ29620297
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at largeQ33342232
Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xLQ33819193
Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophagesQ34000569
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.Q34180844
Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell traffickingQ34347604
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.Q34379673
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)Q34681297
Current molecular models for NADPH oxidase regulation by Rac GTPaseQ34915029
Regulation of mammalian Ste20 (Mst) kinasesQ35122214
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundanceQ35621419
The phenotype of human STK4 deficiencyQ35885278
The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes.Q35894211
Protein kinases of the Hippo pathway: regulation and substratesQ36371333
Recognition and signaling by toll-like receptors.Q36527707
The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells.Q37010249
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammalsQ37105079
T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodesQ37267531
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.Q37297383
MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survivalQ37298578
The Hippo pathway: regulators and regulationsQ38083640
The Hippo pathway and human cancer.Q38087215
Pathogen recognition receptors: ligands and signaling pathways by Toll-like receptorsQ38097498
Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune diseaseQ39031565
CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complexQ39797161
Regulation of neuronal cell death by MST1-FOXO1 signalingQ39883289
Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiencyQ40816848
The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6.Q41509672
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogeneQ42064207
A cell-intrinsic role for Mst1 in regulating thymocyte egress.Q43289467
Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier functionQ43579834
Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymusQ61207271
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectreactive oxygen speciesQ424361
P304page(s)1142-1152
P577publication date2015-09-28
P1433published inNature ImmunologyQ1071725
P1476titleKinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity
P478volume16

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