The complex entanglement of Hippo-Yap/Taz signaling in tumor immunity

scientific article published on 07 January 2019

The complex entanglement of Hippo-Yap/Taz signaling in tumor immunity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41388-018-0649-6
P698PubMed publication ID30617303

P2093author name stringChunling Yi
Shannon M White
Shigekazu Murakami
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Mst1-FoxO signaling protects Naïve T lymphocytes from cellular oxidative stress in miceQ21091167
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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth controlQ24299106
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Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinomaQ34246014
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The Hippo Pathway Kinases LATS1/2 Suppress Cancer ImmunityQ34546530
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Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cellQ36170597
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activityQ36200269
STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinomaQ36266490
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Targeting YAP-Dependent MDSC Infiltration Impairs Tumor ProgressionQ36447669
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The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells.Q37010249
LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.Q37061204
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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.Q37331580
Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responsesQ37435081
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Dendritic cell MST1 inhibits Th17 differentiationQ37630340
Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacyQ37736296
Hippo effector YAP directly regulates the expression of PD-L1 transcripts in EGFR-TKI-resistant lung adenocarcinomaQ38401343
Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.Q38970419
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Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune diseaseQ39031565
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YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation.Q39155971
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The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathwayQ39394211
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Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy.Q40050674
Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockadeQ40272124
Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF.Q40885761
Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma.Q41858851
Organ size control is dominant over Rb family inactivation to restrict proliferation in vivoQ41892098
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Modulating F-actin organization induces organ growth by affecting the Hippo pathwayQ42760112
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Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.Q47234408
Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinomaQ47864262
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The Epithelial Circumferential Actin Belt Regulates YAP/TAZ through Nucleocytoplasmic Shuttling of MerlinQ47972634
Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity.Q48043368
YAP-induced PD-L1 expression drives immune evasion in BRAFi-resistant melanoma.Q48139568
The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells.Q48144535
Targeting IRF3 as a YAP agonist therapy against gastric cancer.Q48232435
Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamicsQ48277126
YAP regulates PD-L1 expression in human NSCLC cells.Q49569691
The Hippo pathway component TAZ promotes immune evasion in human cancer through PD-L1.Q50019997
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Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling mechanism.Q50896241
P433issue16
P304page(s)2899-2909
P577publication date2019-01-07
P1433published inOncogeneQ1568657
P1476titleThe complex entanglement of Hippo-Yap/Taz signaling in tumor immunity
P478volume38

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cites work (P2860)
Q95320552Correction of the tumor suppressor Salvador homolog-1 deficiency in tumors by lycorine as a new strategy in lung cancer therapy
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Q99371197Serum exosomal microRNA transcriptome profiling in subacute spinal cord injured rats
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Q84957646The Hippo Pathway and Viral Infections

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